LOCUS       NM_001008739             557 bp    mRNA    linear   PRI 16-FEB-2025
DEFINITION  Homo sapiens peroxisomal biogenesis factor 39 (PEX39), mRNA.
ACCESSION   NM_001008739 XM_496809
VERSION     NM_001008739.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Pedrosa,A.G., Reglinski,K., Lismont,C., Kors,S., Costello,J.,
            Rodrigues,T.A., Marques,M., Linka,N., Argyriou,C., Weinhofer,I.,
            Kocherlakota,S., Riccio,V., Ferreira,V., Di Cara,F., Ferreira,A.R.,
            Francisco,T., Azevedo,J.E. and Ribeiro,D.
  TITLE     Peroxisomes : novel findings and future directions
  JOURNAL   Histochem Cell Biol 159 (5), 379-387 (2023)
   PUBMED   37160800
REFERENCE   2  (bases 1 to 557)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 557)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 557)
  AUTHORS   Chen,S., Fragoza,R., Klei,L., Liu,Y., Wang,J., Roeder,K., Devlin,B.
            and Yu,H.
  TITLE     An interactome perturbation framework prioritizes damaging missense
            mutations for developmental disorders
  JOURNAL   Nat Genet 50 (7), 1032-1040 (2018)
   PUBMED   29892012
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035587.5 and BC051007.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001008739.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC094854.1, BQ671656.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000408925.4/ ENSP00000386146.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 AL035587.5         60583-60587
            6-557               BC051007.1         1-552
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p21.1"
     gene            1..557
                     /gene="PEX39"
                     /gene_synonym="C6orf226"
                     /note="peroxisomal biogenesis factor 39"
                     /db_xref="GeneID:441150"
                     /db_xref="HGNC:HGNC:34431"
     exon            1..557
                     /gene="PEX39"
                     /gene_synonym="C6orf226"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..339
                     /gene="PEX39"
                     /gene_synonym="C6orf226"
                     /note="uncharacterized protein C6orf226"
                     /codon_start=1
                     /product="peroxisomal biogenesis factor 39"
                     /protein_id="NP_001008739.1"
                     /db_xref="CCDS:CCDS43463.1"
                     /db_xref="GeneID:441150"
                     /db_xref="HGNC:HGNC:34431"
                     /translation="MERPRSPQCSAPASASASVTLAQLLQLVQQGQELPGLEKRHIAA
                     IHGEPTASRLPRRPKPWEAAALAESLPPPTLRIGTAPAEPGLVEAATAPSSWHTVGP"
     regulatory      536..541
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PEX39"
                     /gene_synonym="C6orf226"
                     /note="hexamer: AATAAA"
     polyA_site      557
                     /gene="PEX39"
                     /gene_synonym="C6orf226"
                     /note="major polyA site"
ORIGIN      
        1 gcattacacg ccggtcagga ttcgcgaccc gacatggagc gtccccgcag tccccaatgc
       61 tcggccccgg cctctgcctc agcttcggtt accctggcgc agctcctgca gctggtccag
      121 cagggccagg aactcccggg cctggagaaa cgccacatcg cggcgatcca cggcgaaccc
      181 acagcgtccc ggctgccgcg gaggcccaag ccctgggagg ccgcggcttt ggctgagtcc
      241 cttccccctc cgaccctcag gataggaacg gccccggcgg agcctggctt ggttgaggca
      301 gcgactgcgc cttcttcatg gcatacagtg ggcccctgag gttccaggtc ctttgcggcg
      361 gcgatctgga gggcgtggct acaggacccg ggatgccatt cagttactca tcttttatgc
      421 tttcgtcctg acctgtctca actagacttg ctcctgcaac caccatgggg gttttgcatt
      481 tacatttgtg gaccatgtta cagttaagaa aaatcctgtt tcagtcctta tatgtaataa
      541 aatgttttat gatgtaa
//
