LOCUS       NM_001010868            1344 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens chromosome 6 open reading frame 163 (C6orf163), mRNA.
ACCESSION   NM_001010868 XM_116497
VERSION     NM_001010868.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1344)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL096817.12.
            
            On Nov 22, 2018 this sequence version replaced NM_001010868.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.218168.1,
                                           ERR3218367.244227.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000388923.5/ ENSP00000373575.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-435               AL096817.12        46891-47325
            436-530             AL096817.12        50890-50984
            531-638             AL096817.12        52472-52579
            639-841             AL096817.12        58379-58581
            842-1344            AL096817.12        67039-67541
FEATURES             Location/Qualifiers
     source          1..1344
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q15"
     gene            1..1344
                     /gene="C6orf163"
                     /note="chromosome 6 open reading frame 163"
                     /db_xref="GeneID:206412"
                     /db_xref="HGNC:HGNC:21403"
     exon            1..435
                     /gene="C6orf163"
                     /inference="alignment:Splign:2.1.0"
     CDS             288..1277
                     /gene="C6orf163"
                     /codon_start=1
                     /product="uncharacterized protein C6orf163"
                     /protein_id="NP_001010868.2"
                     /db_xref="CCDS:CCDS55042.1"
                     /db_xref="GeneID:206412"
                     /db_xref="HGNC:HGNC:21403"
                     /translation="MIRNSDYKNFVCCAVCNKIIPPAPFGKTFKRIHEYKPLKTRFYT
                     HKDILDIGANILKKEEQFQEDILREHIAKAEAEVWAQANERQKQAVEKALEEANDRHK
                     IEIQILKEEHQKDLQEVTAKTKTEMYQNMDDEMKREHLAAEQRMVHRIQRIMMECHRE
                     KVEAVEKARAEERHIAQEAIQAQKSKAVEEIVNTGVTVIKDEKTSVARLMREKEHEMS
                     ILYGIAQRQRQEEVQEVLQEAEKTHQATLGNMMDKLANTQGELLSIAKQLGIMTNWKD
                     FLEEELQETRMAFQKYINYTFPKLSPGHADFILPERKKTPSNLVIKENKTTLD"
     exon            436..530
                     /gene="C6orf163"
                     /inference="alignment:Splign:2.1.0"
     exon            531..638
                     /gene="C6orf163"
                     /inference="alignment:Splign:2.1.0"
     exon            639..841
                     /gene="C6orf163"
                     /inference="alignment:Splign:2.1.0"
     exon            842..1344
                     /gene="C6orf163"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1324..1329
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C6orf163"
                     /note="hexamer: AATAAA"
     polyA_site      1344
                     /gene="C6orf163"
                     /note="major polyA site"
ORIGIN      
        1 aagttaacaa cttaatgcta gagtctggga aggagcaact acttaaatct tcccaaatct
       61 ggtgcccata ccttctatgg caggggcttt tagcaccatt ctttaacgtt agacacataa
      121 ccacagccta atcacttgaa ccatttaatc cttaccagcc tctagcatta tcctaaaacc
      181 ctgaacctct tccagctttc ttaaactttc agcttttctt gaaacgactt tttctgattc
      241 taagattatt ttaactgtaa gtaggagaag acatctgaaa tttaactatg atcagaaatt
      301 cagattacaa aaactttgtt tgctgtgctg tttgtaataa aataattcca ccagcccctt
      361 ttggaaaaac cttcaaacgg atccatgaat acaagccact taagacacgc ttttacactc
      421 acaaagacat actagatatt ggggcaaata ttctgaaaaa agaagagcag tttcaagaag
      481 atatactcag agaacacatt gcgaaagcag aagctgaagt atgggctcag gctaatgaac
      541 gtcaaaaaca agcagtggag aaagcacttg aagaagcaaa tgacagacac aaaattgaaa
      601 ttcagatttt gaaagaggaa catcagaaag atttacagga agtgacagct aaaactaaga
      661 cagagatgta tcaaaacatg gatgacgaaa tgaagagaga gcacttggct gcagaacagc
      721 gcatggtcca cagaatccaa aggattatga tggaatgcca cagagagaag gtcgaagctg
      781 tggagaaagc cagggctgaa gaaagacaca tcgcccagga agcaatccag gcccagaaaa
      841 gcaaagccgt ggaggaaatt gtgaatactg gtgtcacagt tattaaggat gagaagacca
      901 gtgtggcccg actgatgagg gaaaaagaac atgaaatgag catcctctat ggcatagctc
      961 agaggcagag gcaagaagag gtacaggaag tgcttcaaga agcagagaaa acacatcagg
     1021 ccactcttgg caatatgatg gataaactgg ctaacaccca gggggagctg ctgtctatag
     1081 caaaacaact gggaatcatg acaaattgga aagatttcct agaggaggaa ttacaggaaa
     1141 ccaggatggc atttcaaaaa tacatcaatt atacctttcc taagctttca ccaggacatg
     1201 cagattttat tctgccagaa agaaagaaaa caccttctaa tcttgttatt aaggagaaca
     1261 aaacaactct tgattagaag tcttcagttg aaattccact acaaaagaca tcattccaga
     1321 ctaaataaat ttactcaaaa acca
//
