LOCUS       NM_001164446            6385 bp    mRNA    linear   PRI 24-MAY-2024
DEFINITION  Homo sapiens chromosome 6 open reading frame 132 (C6orf132), mRNA.
ACCESSION   NM_001164446 XM_930012
VERSION     NM_001164446.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6385)
  AUTHORS   Chen,C., Shen,N., Chen,Y., Jiang,P., Sun,W., Wang,Q., Wang,Z.,
            Jiang,Y., Cheng,W., Fu,S. and Wang,S.
  TITLE     LncCCLM inhibits lymphatic metastasis of cervical cancer by
            promoting STAU1-mediated IGF-1 mRNA degradation
  JOURNAL   Cancer Lett 518, 169-179 (2021)
   PUBMED   34273467
REFERENCE   2  (bases 1 to 6385)
  AUTHORS   Xie,T., Deng,L., Mei,P., Zhou,Y., Wang,B., Zhang,J., Lin,J.,
            Wei,Y., Zhang,X. and Xu,R.
  TITLE     Genome-wide association study combining pathway analysis for
            typical sporadic amyotrophic lateral sclerosis in Chinese Han
            populations
  JOURNAL   Neurobiol Aging 35 (7), 1778 (2014)
   PUBMED   24529757
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL096814.26, KF458156.1 and AL512274.9.
            
            On Nov 23, 2018 this sequence version replaced NM_001164446.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.2054657.1,
                                           SRR14038193.1048322.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968189,
                                           SAMEA1968540 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000341865.9/ ENSP00000341368.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                AL096814.26        157595-157631
            38-102              KF458156.1         1-65                c
            103-321             AL096814.26        157697-157915
            322-428             AL512274.9         72860-72966         c
            429-504             AL512274.9         54404-54479         c
            505-3625            AL512274.9         48651-51771         c
            3626-6385           AL512274.9         45307-48066         c
FEATURES             Location/Qualifiers
     source          1..6385
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p21.1"
     gene            1..6385
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /note="chromosome 6 open reading frame 132"
                     /db_xref="GeneID:647024"
                     /db_xref="HGNC:HGNC:21288"
                     /db_xref="MIM:620839"
     exon            1..321
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..3743
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /note="cervical cancer lymphatic metastasis-associated
                     lncRNA"
                     /codon_start=1
                     /product="uncharacterized protein C6orf132"
                     /protein_id="NP_001157918.1"
                     /db_xref="CCDS:CCDS47428.1"
                     /db_xref="GeneID:647024"
                     /db_xref="HGNC:HGNC:21288"
                     /db_xref="MIM:620839"
                     /translation="MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEG
                     TGGFDGIYYGDNRFNTVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDD
                     FADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGG
                     SPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPA
                     PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASP
                     PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA
                     PSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPP
                     APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSP
                     ENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR
                     LPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI
                     RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTT
                     LLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTP
                     LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEA
                     TRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPG
                     EPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVG
                     AALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPN
                     KWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSN
                     KREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGA
                     PPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSS
                     PNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAP
                     AAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS"
     exon            322..428
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /inference="alignment:Splign:2.1.0"
     exon            429..504
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /inference="alignment:Splign:2.1.0"
     exon            505..3625
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /inference="alignment:Splign:2.1.0"
     exon            3626..6385
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      4087
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /note="major polyA site"
     regulatory      5816..5821
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /note="hexamer: TATAAA"
     polyA_site      5837
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /note="major polyA site"
     regulatory      6361..6366
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
                     /note="hexamer: CATAAA"
     polyA_site      6385
                     /gene="C6orf132"
                     /gene_synonym="bA7K24.2; LncCCLM"
ORIGIN      
        1 atttcccggc aagcggcggc gcccgcagca cctgttgccc ggtgcgcggg cggggaggac
       61 ggcgggggac atggcctggt agagtcccct ggggagaccg tgctgagttc agtccggggc
      121 agggcagggc gagggaggga aggtccttcc ctggcgcccg cgcgggctgc ggcagcatga
      181 aaaagaagca gacggtgcag ggcaccttca gcaaactctt cgggaagaag cacaccacga
      241 cccccagcac ctccctctac gccaccaatc cgccctggat cttcacccag gaggccccgg
      301 aggaggggac cgggggcttc gatggcatct attatggaga caatcggttt aacacagtga
      361 gcgagtcagg aacagccacg ctgaaagctc ggccaagagt ccggcccctg ctgaccttcc
      421 ttccgctgaa tgcccaggaa aaccatgggc tggctgtgcc caccccctcg gttccagatg
      481 attttgcaga caaagaagtg acaggtacca gctcactagt caatggcaac ctccgactgt
      541 acagctctgt gggtgacctg aggcctggac aatatggcca ggatctactc atccccccac
      601 ctcccccagg cccagcccca gggccccctc aggacatttc agaacctcca ggggggtcgc
      661 cactgccatc tccaccttcc acagcacccc caccacctcc cctgctgctg gaacccccac
      721 ccccgcccag catggcccca cctccacccc cagtattgga ggccctatcc ccaccacaca
      781 ctctttcctc cccatccata cccacccctc ctgacttcat tccccctgcc ccacccttgg
      841 cctttctagc ccccccaccg cctcctgtgc cagccccagc acccccagct ccagcatctc
      901 ctcacacagt ggggactcgt ctctttcccc ctgggggtgt caccaagtgg aaatcagatg
      961 tagcactgaa tggcaggcag gcagaggcca ccagagccag ccccccgaga agccctgctg
     1021 agccaaaggg gagcgccctg ggacctaacc cagagcccca tctcaccttc ccccgttctt
     1081 tcaaagtgcc tcccccaacc ccagtcagga cttcgtccat cccagttcag gaagcacaag
     1141 aggctccccg aaaggaagag ggggccacca agaaggctcc cagccgactc ccactgcctc
     1201 ccagcttcca catccgcccc gcctcccagg tctacccaga cagggccccc gagccagact
     1261 gccctgggga gctcaaggcc acagcaccag ccagcccaag gcttggccag tcccagtccc
     1321 aagcagatga acgagctggg actccgcctc cagcccctcc cctgccccct cctgcacccc
     1381 ccctccctcc cccagcaccc ccacttcccc cagctgcacc tcctttgccc tgtgctcaga
     1441 aggcagccca tccacctgct gggtttacaa aaacccctaa atccagctct cctgctctca
     1501 aacccaaacc caaccccccc agcccagaga acacagcgtc ttcagcacct gtggactgga
     1561 gggaccccag ccagatggaa aagctgcgga acgagctggc agcctatctc tgtggctcca
     1621 ggagagagga ccgattcctc agtcacaggc caggcccaac agtggcccct cagagcaagg
     1681 agggcaagaa gggcccccgc ctgcctgaga aggagactct cctgagcctg ccagcaaagg
     1741 acactccccc aggtgttcct gaaaagagtc ttggcggcag cagcctgaca gagacagagg
     1801 ctgcccccag cctgaccctg ccctctgtgg actacattcc ccaagactct ccaactccca
     1861 gtgtgcggca gatccggaat gagctggagg cccggctctc ctcagcagca gagaaggagg
     1921 ctaagcccag cataggatct ctgcccccta agcctcggct agaaggggga agaatttgtg
     1981 aaaacggggc tgatgatgac aaactctcca agcctgtggc caagaatctg ccacctcaat
     2041 ccaccaccct gctgccaact acatcactcc agcccaaggc tatgttggga ccagccatac
     2101 cacccaaggc cacacctgag ccagccatac cacccaaggc tacactttgg ccagccacac
     2161 cacccaaggc cacacttggg ccagccacac cactcaaggc cacatctggg ccaaccacac
     2221 cactcaaggc cacatctggc cctgccatag catctacagc cacaactctg cccaccacca
     2281 catcccaact gatggcagag aaggactcag gcccagctgg ccagccagag aagccagcat
     2341 ctcaagaagt ttccactccc tcccaggcaa ggggagaggg gtccccctca gaggccacta
     2401 ggctgcccac acagggagcc cgctcatctg cagccttccc accaaagaca tctcctggtg
     2461 gaggagaggt gccatgtctc tacaagcccc actgccacca gagcagcctc agccgtgagg
     2521 ttgctgtggt gatgcccacc ctggccagag gaggggctgc agggccaggg gagcccgtgg
     2581 aggtgaagga gcccccaggg ctgccagcca agcctcctgc ctcggcccag cccactgatg
     2641 aactcctcag gcacccggtg actggggagg tggtggagcg gggctcgccg atggccctgc
     2701 tcctggcggc caggcagagg gctcagaagg gaaggtctgt aggggctgcc ctgggtcggt
     2761 cctctctgcc aggaagtctc cgtgaccaca gccaccaagc cgaggccagc tctgacagca
     2821 tcttccacag ccagggcacg cccaactcct tcactgtggt gcccaagtta cccaaggagg
     2881 ctgagaagga ctccccgctg acgaccgaaa tacccaataa gtgggggccg cggctgggaa
     2941 gagacgcaga gggcacagag ctgagccgca ggcacaactg gacaaagcca gagccccagg
     3001 cccctgtggc ctgggaaaga gtagctccct ccaacctccc ccagggccac ccgctgccca
     3061 agtccttctc ctccccacct tctccttcga acaagaggga ggaggaggag gaggagttca
     3121 acttcgaggt catcccaccg ccgccagagt tcagcaatga ccctgagccc ccggccccgg
     3181 ccctccagta tctgggccgc cagagctccc ctccccggaa caactactca gacttgaggc
     3241 agctcccgaa cgctggcccc ggggcgcccc cggctctcgg cttctcgcgc tttcccgcgg
     3301 gcgcgcgcta cgccggggct gggggcctgg agcgcttctc gggagggggc cgctcgctca
     3361 taaagaagcg cctgtacgtc ggggagccgc accgaggccc agggctaccc cacggtggca
     3421 ccggccgcag cctgagctct cccaactgct tcgggccgca gcccggaggc cccgagatgc
     3481 ggcgcgtgaa ctcggcgggt cgcgcgcccc ccggaggcct gcacgcgccg aggctgtccc
     3541 tggagggcgc cgcccggggc gccgcggagg ccaagcacaa agcgcccggc agcgccgact
     3601 acggcttcgc cccagctgcc ggcaggtctc cctacaccac cacccgctat ggaagcccca
     3661 tcaacacgtt caccgtgagg cctgggaccc gccatcccat ctcctatgtc tgctcagggg
     3721 cccatcggaa agccacctcc tgagccaggg gttctcttag ctctactcca acaaactgtg
     3781 tctttaagga tctgggcact tgtttcttgt ggggggtggg aggtacacag caggtgttgg
     3841 gcgacctgac tcagacacag aggagtcttt gatccccaaa gaccaacgat gagaagcagt
     3901 ggcccaggaa gaccgagagt gggcttctgt ttcccaaagc gctggtgtga ctgtggactg
     3961 tttacacgtg gggggtggga ggggaaggag ggtagagaga aggaaccatt aaggacctgg
     4021 gcgctgagtt tctgctctct ggtactatct gctttagcaa gagttattta aaacagtttt
     4081 acaagcacgg cctactgagc aggttctgaa agcaaggggt ggggcactga ctgaactgga
     4141 acccatcgag atagctgtga ttgcctgtca ggcccttgca aagggctgag gcccagctct
     4201 gtctggtggg tgtgcagggc accgaaggga gatctttagc ctccatcacc tgccatccca
     4261 agcaagagtg gacacctggg gttcctagcc gcattgaggt gggaccagga atgtgtatgt
     4321 ataacatgtg gagaaggacc atgtgtgggg tggggagtga agctcccaca tgtggaatgg
     4381 aagccctttg cattggccaa gggcagaggt gggagattga tggttcattt ttccttggcc
     4441 ctagccctta gctacaggga ggcctagaga gaggacactt ggcaagttta ggatgggaaa
     4501 caaggttaag cctggctttg ctattcagac ctgtgcagcc ctgattttgg ggactgggcc
     4561 caaggagcca tgagtcttag gcttgacact aggggcctta catggccagg tctcatatgg
     4621 gatttggaga aggcattttt cctaacactg atactacaag tcaccaatac tcttgatgcc
     4681 ttaagatgct agaaagcctt ggagagtgga ggcagcagag atgggaatgg aggtctgaag
     4741 aagcttgctg ctgttgggga atgtgtttgg gaaagtcaag agtggtagga ttggttggct
     4801 gggcgcggtg gctcacacct gtaatcccag cactttggga ggccgaggcc ggtggatcac
     4861 ttgaggtcag aagttcgaga ccagcctgcc caaatggtga aaccccatct ctactaaaaa
     4921 tacggaaaaa aaaaaaaaaa gagtgctagg attgggccag ttaagagcag gggagacctg
     4981 gctgggcatg gtggctcaca cctgtaattc tagcactttg ggaggctgag gcgggtggat
     5041 catgaggtca agagattaag accatcctgg cctacatggc gaaaccctgt ctctactaaa
     5101 aataaaaaaa tgacctgggc atggtggtgg gcgcctgtag tcccagctac tcggggcgct
     5161 gaggcaggag aatcgctcga acccaggagg tggaggttgc agtgagccga gattgcacaa
     5221 ttgcactcca gcctggcgac agagcgagac tcgtctcaaa aaaaaaaaaa aaaaaaaaaa
     5281 aaggagcagg ggagacctat cagtagggtg accacgtgtc ctttgcctgg gcagtccagg
     5341 tttatgcttg ttttccagtg aattagaccc ccttccactt ttcaaaaaag tcctggttta
     5401 gatgctgtga tcaccaaaca tatcaggaaa caatattcct tggtcttgct tccctatctt
     5461 caggtactgg tgggccaaat tcctgggacc aggtcaaggt gggctgcctc agtaagaagg
     5521 aaggactgga gagtgcccat ttcagaggag caggctggtg ggggccagcc agaaagtagt
     5581 tccctttggg gggaagatgt tggaccttta ttatttgtgg taaccagccg aggctggttg
     5641 tcaggacagc aggtgagcca ctttagggaa gaaagtgcag gggtgggtgg atgcccagat
     5701 taccaaggcc agccaccctg atggggtagg gtctggttat ctgtgttcaa gaagcaaatc
     5761 ccaccccagc cccagcacta gctctctatg tatgtatttt ccctgtacaa tgttttataa
     5821 aagagatcat taatttatct gctatgttaa ggctcgaggg gtggggcgta gactctcagc
     5881 tgtatattgc tctggggtgg gcagggaagg ctgagtctca cttgacttgg aagataaaca
     5941 ggccagtttg gactggcctc cagctccgtg gctgtgtttg tctaacaagg atttgggtaa
     6001 ctactggata caagccactg tgcttagtat ggatagactg ccatcagctc acccacatga
     6061 ctcctgttca tggcaagcta atagtctgtc tggtggaaga ggattgaaaa agcacacaaa
     6121 aacatcataa attacaagga gtagtaagaa ggaaaaaaca gggaacgtga gagaataact
     6181 agcgagtggg gagaggagtg gatttacttt aacagggtag tcagggaagg cctcttgtgg
     6241 tggtgacata ctgatttagg caaagcgtcc agcacgtgcc tagcgcttag tagttgctca
     6301 gcaaatggca tctttgggtg atgaatacct cacatttgta tatggcctgt cacagttttc
     6361 cataaagctt ttttttttaa ggcca
//
