LOCUS       NM_001145132             721 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens chromosome 5 open reading frame 52 (C5orf52), mRNA.
ACCESSION   NM_001145132
VERSION     NM_001145132.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Schmutz,J., Martin,J., Terry,A., Couronne,O., Grimwood,J.,
            Lowry,S., Gordon,L.A., Scott,D., Xie,G., Huang,W., Hellsten,U.,
            Tran-Gyamfi,M., She,X., Prabhakar,S., Aerts,A., Altherr,M.,
            Bajorek,E., Black,S., Branscomb,E., Caoile,C., Challacombe,J.F.,
            Chan,Y.M., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Glavina,T., Gomez,M., Gonzales,E., Goodstein,D.,
            Grigoriev,I., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Israni,S.,
            Jett,J., Kadner,K., Kimball,H., Kobayashi,A., Lopez,F., Lou,Y.,
            Martinez,D., Medina,C., Morgan,J., Nandkeshwar,R., Noonan,J.P.,
            Pitluck,S., Pollard,M., Predki,P., Priest,J., Ramirez,L.,
            Retterer,J., Rodriguez,A., Rogers,S., Salamov,A., Salazar,A.,
            Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N., Wheeler,J.,
            Wu,K., Yang,J., Dickson,M., Cheng,J.F., Eichler,E.E., Olsen,A.,
            Pennacchio,L.A., Rokhsar,D.S., Richardson,P., Lucas,S.M.,
            Myers,R.M. and Rubin,E.M.
  TITLE     The DNA sequence and comparative analysis of human chromosome 5
  JOURNAL   Nature 431 (7006), 268-274 (2004)
   PUBMED   15372022
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008694.6, BG721329.1 and AI187821.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001145132.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HY200598.1, BG721329.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000409999.4/ ENSP00000387027.3
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-204               AC008694.6         116638-116841
            205-353             BG721329.1         8-156
            354-380             AC008694.6         120256-120282
            381-473             BG721329.1         184-276
            474-717             AI187821.1         12-255              c
            718-721             AC008694.6         125260-125263
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q33.3"
     gene            1..721
                     /gene="C5orf52"
                     /note="chromosome 5 open reading frame 52"
                     /db_xref="GeneID:100190949"
                     /db_xref="HGNC:HGNC:35121"
     exon            1..294
                     /gene="C5orf52"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..562
                     /gene="C5orf52"
                     /codon_start=1
                     /product="uncharacterized protein C5orf52"
                     /protein_id="NP_001138604.1"
                     /db_xref="CCDS:CCDS47329.1"
                     /db_xref="GeneID:100190949"
                     /db_xref="HGNC:HGNC:35121"
                     /translation="MTQPTRPSVTCDQGSSTIGGTAAQATTSSSATSGSNYQRDRLGR
                     RPEIGVGGQPQICFPRPRSAQQPVLFSLMNSSEAAMKKTLPKSHLSRVIIHDNRITQR
                     IYEMEVSALEKTKKKISHYYEHLKKKFMTEQLRKLGRWREESVNSNRYLTFGIPPPV"
     exon            295..403
                     /gene="C5orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            404..721
                     /gene="C5orf52"
                     /inference="alignment:Splign:2.1.0"
     regulatory      685..690
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C5orf52"
                     /note="hexamer: AATAAA"
     polyA_site      721
                     /gene="C5orf52"
                     /note="major polyA site"
ORIGIN      
        1 actccgcgtc agcgcgcgcc cacctaggtg ggctggcaac cagccaccag tttccaactc
       61 tttctccaac agggaagccg caatgacaca gccgactagg ccctcggtca cctgtgacca
      121 gggatcctcc acgatcggcg ggaccgccgc ccaggcgacc accagttcca gcgccacctc
      181 gggttcgaac taccagcgcg atagactcgg ccgccgccca gaaatcggcg tagggggtca
      241 gccgcagatc tgctttccgc ggccgaggtc cgcgcagcag ccggtgctgt tcagcttaat
      301 gaattccagt gaagcagcga tgaaaaaaac tttacccaag agccatttat ctcgggtgat
      361 tattcatgat aaccgcatca cacaacgaat ctatgagatg gaggtgagcg ctttagagaa
      421 gaccaagaaa aagatcagcc actactatga acacctgaaa aaaaagttca tgacagagca
      481 gctcagaaag ctcgggcgat ggagagagga atccgtgaac agcaaccggt acttaacctt
      541 cgggatacca ccaccagttt aaactccagt ctcccaagaa aggccaacca ccctagttct
      601 ggcaaaggga tctgccccag ggtcacgatg acaccagtgt gacccgagga gaactagtaa
      661 ctacaaccta cacaactgta gaacaataaa cagaaaccag cagacagcgg agcataataa
      721 a
//
