LOCUS       NM_001080531             904 bp    mRNA    linear   PRI 15-FEB-2024
DEFINITION  Homo sapiens chromosome 4 open reading frame 51 (C4orf51), mRNA.
ACCESSION   NM_001080531 XM_929540
VERSION     NM_001080531.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Vlaikou,A.M., Manolakos,E., Noutsopoulos,D., Markopoulos,G.,
            Liehr,T., Vetro,A., Ziegler,M., Weise,A., Kreskowski,K.,
            Papoulidis,I., Thomaidis,L. and Syrrou,M.
  TITLE     An interstitial 4q31.21q31.22 microdeletion associated with
            developmental delay: case report and literature review
  JOURNAL   Cytogenet Genome Res 142 (4), 227-238 (2014)
   PUBMED   24733116
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093864.3 and AC107212.5.
            
            On Dec 23, 2019 this sequence version replaced NM_001080531.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DY655030.1, DY654883.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000438731.7/ ENSP00000391404.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-291               AC093864.3         98273-98563
            292-365             AC093864.3         114686-114759
            366-424             AC107212.5         18703-18761
            425-485             AC107212.5         20961-21021
            486-559             AC107212.5         21684-21757
            560-904             AC107212.5         24245-24589
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q31.21"
     gene            1..904
                     /gene="C4orf51"
                     /note="chromosome 4 open reading frame 51"
                     /db_xref="GeneID:646603"
                     /db_xref="HGNC:HGNC:37264"
     exon            1..291
                     /gene="C4orf51"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..667
                     /gene="C4orf51"
                     /codon_start=1
                     /product="uncharacterized protein C4orf51"
                     /protein_id="NP_001074000.1"
                     /db_xref="CCDS:CCDS47140.1"
                     /db_xref="GeneID:646603"
                     /db_xref="HGNC:HGNC:37264"
                     /translation="MSHYFYLTPQILLPFSPLTSQEFDLIRRKAGASWQDETRWSDSS
                     VTTYTGSYRKKQLDKSMCSQFSFRAGQHEPECKQMSLTNSSACHLLCWAGTQETTDIK
                     GLFPDITRPFKKSFDVKHGVAHQIWDFGDCFPTPPNYGKYCVRPKKPAQEALINYSRR
                     GKGVLKHLHGRCDSESKVCSSEDSEADRYSDYGWGGPSSPFN"
     exon            292..365
                     /gene="C4orf51"
                     /inference="alignment:Splign:2.1.0"
     exon            366..424
                     /gene="C4orf51"
                     /inference="alignment:Splign:2.1.0"
     exon            425..485
                     /gene="C4orf51"
                     /inference="alignment:Splign:2.1.0"
     exon            486..559
                     /gene="C4orf51"
                     /inference="alignment:Splign:2.1.0"
     exon            560..904
                     /gene="C4orf51"
                     /inference="alignment:Splign:2.1.0"
     regulatory      881..886
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C4orf51"
                     /note="hexamer: ATTAAA"
     polyA_site      904
                     /gene="C4orf51"
                     /note="major polyA site"
ORIGIN      
        1 aattcttcat tatgcagagg acttgacaag ttgttttcca gagaggccgt tcgtagttat
       61 gtcacactac ttctacttga ctccacaaat tcttctgccc tttagccctc ttacttctca
      121 agagtttgat ctgatcagac gcaaggctgg agcatcttgg caggatgaaa cacgatggtc
      181 agattcttcc gtgacaacat acacaggcag ttaccggaaa aaacaactgg acaagtccat
      241 gtgcagccaa ttttctttta gagcaggaca gcatgagcct gagtgtaaac agatgtcatt
      301 gacaaacagt tctgcctgtc atcttctctg ctgggctggt acccaagaga ctacagatat
      361 caaaggacta ttccctgata taaccaggcc ctttaaaaag tcatttgatg tcaagcatgg
      421 agtggcacat caaatttggg attttggtga ttgttttccg acacctccaa attatggaaa
      481 atactgtgtg agacctaaaa agccagcaca ggaggccctg ataaactaca gtcgacgagg
      541 gaaaggtgtc ctaaagcatc ttcatggacg gtgcgattct gaaagcaagg tttgctcatc
      601 tgaggattca gaagctgatc gatactccga ttatggctgg ggaggaccct catcgccatt
      661 taactgagtt ggaaaatgaa gccacaaggc tggaggcgtg gagtttgctt aataaacaac
      721 tttgaggtat ggggccctcc caacaccctc cccccacccg ccccgcccag gaacgtctgg
      781 accctggcag gttggctttc tgggacaatt ccatgggctt catttatcag ttttttccct
      841 ttttaattgg tggagagaga caaaagtttt tataatcttt attaaatttt cctttttaaa
      901 taaa
//
