LOCUS       NM_144645                908 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens chromosome 4 open reading frame 36 (C4orf36),
            transcript variant 1, mRNA.
ACCESSION   NM_144645
VERSION     NM_144645.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Wade,T.D., Gordon,S., Medland,S., Bulik,C.M., Heath,A.C.,
            Montgomery,G.W. and Martin,N.G.
  TITLE     Genetic variants associated with disordered eating
  JOURNAL   Int J Eat Disord 46 (6), 594-608 (2013)
   PUBMED   23568457
REFERENCE   2  (bases 1 to 908)
  AUTHORS   Kwee,L.C., Liu,Y., Haynes,C., Gibson,J.R., Stone,A.,
            Schichman,S.A., Kamel,F., Nelson,L.M., Topol,B., Van den
            Eeden,S.K., Tanner,C.M., Cudkowicz,M.E., Grasso,D.L., Lawson,R.,
            Muralidhar,S., Oddone,E.Z., Schmidt,S. and Hauser,M.A.
  TITLE     A high-density genome-wide association screen of sporadic ALS in US
            veterans
  JOURNAL   PLoS One 7 (3), e32768 (2012)
   PUBMED   22470424
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093827.3.
            
            On Nov 23, 2018 this sequence version replaced NM_144645.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016746.1, BI459738.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000295898.8/ ENSP00000295898.3
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               AC093827.3         45053-45292         c
            241-378             AC093827.3         44326-44463         c
            379-533             AC093827.3         40991-41145         c
            534-669             AC093827.3         40628-40763         c
            670-908             AC093827.3         29075-29313         c
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q21.3"
     gene            1..908
                     /gene="C4orf36"
                     /note="chromosome 4 open reading frame 36"
                     /db_xref="GeneID:132989"
                     /db_xref="HGNC:HGNC:28386"
     exon            1..240
                     /gene="C4orf36"
                     /inference="alignment:Splign:2.1.0"
     exon            241..378
                     /gene="C4orf36"
                     /inference="alignment:Splign:2.1.0"
     CDS             314..667
                     /gene="C4orf36"
                     /codon_start=1
                     /product="uncharacterized protein C4orf36"
                     /protein_id="NP_653246.2"
                     /db_xref="CCDS:CCDS3615.1"
                     /db_xref="GeneID:132989"
                     /db_xref="HGNC:HGNC:28386"
                     /translation="MAYGVPRKNTVKTILRGSCYNVQEPWDIALLAKTWSTNLANIKL
                     PFLEEISFGGSVQLTKCTTIKDGLLPSAESIKLEREYEVKRLCKLKCQENTSKEIQLL
                     LRERPAGLRRPLPSK"
     exon            379..533
                     /gene="C4orf36"
                     /inference="alignment:Splign:2.1.0"
     exon            534..669
                     /gene="C4orf36"
                     /inference="alignment:Splign:2.1.0"
     exon            670..908
                     /gene="C4orf36"
                     /inference="alignment:Splign:2.1.0"
     regulatory      889..894
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C4orf36"
                     /note="hexamer: TATAAA"
     polyA_site      908
                     /gene="C4orf36"
                     /note="major polyA site"
ORIGIN      
        1 agactcggcg cccgcggcga gcgggaagga ggcgtgtgcc tgcggcgcgg ccccgaggcg
       61 tgtgcgcggc catgtgcgct tagcgcagcg cgctcttacc tcagtacccc ggccgcgacc
      121 ctccgagccc ctggagcccg ggtaaccagg ccgccggcgc cggctcgcgg ggacccgcca
      181 ccctggaagc cccgcgcaca cagcgcattc ctggcgagtc ggaggcaggg tggggcccag
      241 gtaaagtgaa cagagttatc tgtgacattc catcaggcac ctatgtaacg aaatcatacc
      301 gtaataactc accatggcgt atggagtgcc aagaaagaac acagtgaaaa ccattttgcg
      361 gggcagttgt tataatgtac aggaaccttg ggatattgca ttgcttgcaa agacctggtc
      421 cacaaaccta gccaatatca agttgccttt cttggaagaa atttcatttg gtggttctgt
      481 gcagctcaca aaatgtacca ccattaaaga tggactgctc ccttctgcag aatctatcaa
      541 actcgaaagg gagtatgaag tgaagcgtct ttgtaaactg aagtgtcaag aaaatacatc
      601 taaggaaatt cagcttctcc tgagggaaag gccagccggt ttgagaagac ctcttccatc
      661 taaatgacac ctgaagcgcg gattgtagat gaagaaactc agcagcgccg gcgggaactg
      721 cttctcctgg gccgcccagg acccgctccc ggccccggcc gtcgctgcgc tgcagccatc
      781 ctggcccggc ccccacctca ggaagcctcc cacggcccgc ccagagaccg agaaaatctc
      841 ttaatttcag tggaactcag tttgtttctc tttttaaaca ttgccagtta taaatgtatt
      901 ttatttta
//
