LOCUS       NM_001351622            1807 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens chromosome 3 open reading frame 85 (C3orf85),
            transcript variant 1, mRNA.
ACCESSION   NM_001351622
VERSION     NM_001351622.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1807)
  AUTHORS   Figueiredo,J.C., Hsu,L., Hutter,C.M., Lin,Y., Campbell,P.T.,
            Baron,J.A., Berndt,S.I., Jiao,S., Casey,G., Fortini,B., Chan,A.T.,
            Cotterchio,M., Lemire,M., Gallinger,S., Harrison,T.A., Le
            Marchand,L., Newcomb,P.A., Slattery,M.L., Caan,B.J., Carlson,C.S.,
            Zanke,B.W., Rosse,S.A., Brenner,H., Giovannucci,E.L., Wu,K.,
            Chang-Claude,J., Chanock,S.J., Curtis,K.R., Duggan,D., Gong,J.,
            Haile,R.W., Hayes,R.B., Hoffmeister,M., Hopper,J.L., Jenkins,M.A.,
            Kolonel,L.N., Qu,C., Rudolph,A., Schoen,R.E., Schumacher,F.R.,
            Seminara,D., Stelling,D.L., Thibodeau,S.N., Thornquist,M.,
            Warnick,G.S., Henderson,B.E., Ulrich,C.M., Gauderman,W.J.,
            Potter,J.D., White,E. and Peters,U.
  CONSRTM   CCFR; GECCO
  TITLE     Genome-wide diet-gene interaction analyses for risk of colorectal
            cancer
  JOURNAL   PLoS Genet 10 (4), e1004228 (2014)
   PUBMED   24743840
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1807)
  AUTHORS   Zheng,J.S., Arnett,D.K., Lee,Y.C., Shen,J., Parnell,L.D.,
            Smith,C.E., Richardson,K., Li,D., Borecki,I.B., Ordovas,J.M. and
            Lai,C.Q.
  TITLE     Genome-wide contribution of genotype by environment interaction to
            variation of diabetes-related traits
  JOURNAL   PLoS One 8 (10), e77442 (2013)
   PUBMED   24204828
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC063923.21 and KF457669.1.
            
            On Apr 2, 2019 this sequence version replaced NM_001351622.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189664.146843.1,
                                           SRR5189664.86398.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000622536.6/ ENSP00000489642.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                AC063923.21        132684-132697       c
            15-23               KF457669.1         1-9
            24-76               KF457669.1         112-164
            77-210              AC063923.21        121030-121163       c
            211-1807            AC063923.21        118015-119611       c
FEATURES             Location/Qualifiers
     source          1..1807
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q13.13"
     gene            1..1807
                     /gene="C3orf85"
                     /note="chromosome 3 open reading frame 85"
                     /db_xref="GeneID:401081"
                     /db_xref="HGNC:HGNC:53432"
     exon            1..23
                     /gene="C3orf85"
                     /inference="alignment:Splign:2.1.0"
     exon            24..76
                     /gene="C3orf85"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..300
                     /gene="C3orf85"
                     /note="uncharacterized protein C3orf85"
                     /codon_start=1
                     /product="uncharacterized protein C3orf85 precursor"
                     /protein_id="NP_001338551.1"
                     /db_xref="CCDS:CCDS87119.1"
                     /db_xref="GeneID:401081"
                     /db_xref="HGNC:HGNC:53432"
                     /translation="MAYKMLQVVLCSTLLIGALGAPFLLEDPANQFLRLKRHVNLQDY
                     WDPDHSSDVWVNTLAKQARETWIALKTTAQYYLDMNTFTFDMSTAQ"
     exon            77..210
                     /gene="C3orf85"
                     /inference="alignment:Splign:2.1.0"
     exon            211..1807
                     /gene="C3orf85"
                     /inference="alignment:Splign:2.1.0"
     regulatory      614..619
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C3orf85"
                     /note="hexamer: ATTAAA"
     polyA_site      633
                     /gene="C3orf85"
                     /note="major polyA site"
     regulatory      1640..1645
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C3orf85"
                     /note="hexamer: AATATA"
     polyA_site      1658
                     /gene="C3orf85"
                     /note="major polyA site"
ORIGIN      
        1 gtctcagctc acagggcttc caggatcatg gcctataaaa tgcttcaagt agtcctgtgc
       61 tcaacattgc ttatcggagc attgggagcg ccatttttgt tggaagaccc tgcaaaccag
      121 ttcctacgtc tcaaaagaca tgtaaatttg caggattact gggacccaga tcacagttca
      181 gatgtgtggg taaacacact ggctaagcag gctcgtgaaa catggattgc tttgaaaaca
      241 acagcacagt attatttgga tatgaatacc ttcacctttg acatgtctac tgcccagtaa
      301 atatgttttc ctggttaaag caggaggatg aagatggcag aggttggaat ggcattgtgc
      361 caaaaccatg ggttttagag atctgagggt atatccatgc tgtttactac attatttatt
      421 atgtctgtct caaagttgtt gaaaacagta gttatgaaaa cccatgtagg aaactggaat
      481 aagacattct caataaatgg tagttctcaa aaaaagaact aaaaaaaaaa aaggctgtag
      541 taataacatt taccaaaacg atggcattta tgggaaaagg aaagcaaaaa cataaacaaa
      601 gaaaagtagt ttcattaaac cactctgttc atagctttta ctctctattg cctcttcttt
      661 gagagagttt tttaattcaa agaaggacag ggagctctca aatggagctg atcctcttct
      721 ctcttcttca gtgcttgtcg cattcttaag tcagtcgatt ttaaaaccat gactttgaaa
      781 cgtttttcat caaaggtgta ctgctgagtg gagaatacag ccttacctta atacaacaag
      841 tagatagtgg ctaggaactc aatggaagtc attcacttgt aagtgcaaac ttcttccaag
      901 ttttgtaaaa tttttgtaag ctttgcattc tgttccacaa tttattgatg tttgttttaa
      961 tgtgaaataa cagttttgac tcactggcca ggcacatttt ataatttttt caattaaaac
     1021 tgaaaaattg gccataggga aaagtggact gcatttatcc tataactttc ctaatattca
     1081 tggattacca cctcagtttg agaagcattg agatgataca actaattgcc aagattgccc
     1141 cccaaaatca caggtaaatg gaatttttgt cttcagaagt ctatttatct ccattctcta
     1201 ttctctattt tagttgttct ctcgaacaat ttatttttac cttttaaggt aaatggaaac
     1261 atttccctaa gaccttagtt gatcttatgt ggtcttaaaa caatcttaag cactttttga
     1321 gtggcaagta aatcagaaaa accaaatgcc aagaagttga ctggaaggac tttggcctca
     1381 gcaatttctt ctccaaaagg acactgacag ctgctcagtg tttcacattt cccatcctat
     1441 ggcctagagg tgttttcagt gagaaattta aggctaattt ataacttatt aagttaactg
     1501 ctatccattt ccaataaata tgaacataga tttttaaatt acatctgaac aaacaaaaca
     1561 aagatgatga atcatttagt tttgcagtgg gaaataagtt tgagattgta cataaatata
     1621 tcttcagtgt tttaccaata atatacattt tactaacaca aagtttcatt ctttaattat
     1681 ttaataaaaa attgagaatg tctgtgtatt agggttctcc agagaaacag aaccaatagg
     1741 atatgtatat atagagatgc tcctcaacat acgatggcgt tacatcccaa taaacccgtc
     1801 acacgct
//
