LOCUS       NM_032137               3286 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens chromosome 3 open reading frame 20 (C3orf20),
            transcript variant 1, mRNA.
ACCESSION   NM_032137
VERSION     NM_032137.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3286)
  AUTHORS   Nishizawa,D., Nagashima,M., Kasai,S., Hasegawa,J., Nakayama,K.,
            Ebata,Y., Fukuda,K.I., Ichinohe,T., Hayashida,M. and Ikeda,K.
  TITLE     Associations between the C3orf20 rs12496846 Polymorphism and Both
            Postoperative Analgesia after Orthognathic and Abdominal Surgeries
            and C3orf20 Gene Expression in the Brain
  JOURNAL   Pharmaceutics 14 (4), 727 (2022)
   PUBMED   35456561
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3286)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 3286)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB064418.1, AC090957.1 and BC038406.1.
            
            On May 17, 2019 this sequence version replaced NM_032137.4.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC038406.1, AL834386.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000253697.8/ ENSP00000253697.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                DB064418.1         43-53
            12-12               AC090957.1         40115-40115
            13-38               DB064418.1         55-80
            39-185              BC038406.1         1-147
            186-186             AC090957.1         47206-47206
            187-3286            BC038406.1         149-3248
FEATURES             Location/Qualifiers
     source          1..3286
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p25.1"
     gene            1..3286
                     /gene="C3orf20"
                     /note="chromosome 3 open reading frame 20"
                     /db_xref="GeneID:84077"
                     /db_xref="HGNC:HGNC:25320"
                     /db_xref="MIM:619992"
     exon            1..112
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            113..274
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            275..894
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     CDS             411..3125
                     /gene="C3orf20"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C3orf20"
                     /codon_start=1
                     /product="uncharacterized protein C3orf20 isoform 1"
                     /protein_id="NP_115513.4"
                     /db_xref="CCDS:CCDS33706.1"
                     /db_xref="GeneID:84077"
                     /db_xref="HGNC:HGNC:25320"
                     /db_xref="MIM:619992"
                     /translation="MSYIKSNLELYQQYTAMAPKLLARISKLLMICQNAGISVPKGIR
                     NIFEFTWEELISDPSVPTPSDILGLEVSFGAPLVVLMEPTFVQVPTLKKPLPPPPPAP
                     PRPVLLATTGAAKRSTLSPTMARQVRTHQETLNRFQQQSIHLLTELLRLKMKAMVESM
                     SVGANPLDITRRFVEASQLLHLNAKEMAFNCLISTAGRSGYSSGQLWKESLANMSAIG
                     VNSPYQLIYHSSTACLSFSLSAGKEAKKKIGKSRTTEDVSMPPLHRGVGTPANSLEFS
                     DPCPEAREKLQELCRHIEAERATWKGRNISYPMILRNYKAKMPSHLMLARKGDSQTPG
                     LHYPPTAGAQTLSPTSHPSSANHHFSQHCQEGKAPKKAFKFHYTFYDGSSFVYYPSGN
                     VAVCQIPTCCRGRTITCLFNDIPGFSLLALFNTEGQGCVHYNLKTSCPYVLILDEEGG
                     TTNDQQGYVVHKWSWTSRTETLLSLEYKVNEEMKLKVLGQDSITVTFTSLNETVTLTV
                     SANNCPHGMAYDKRLNRRISNMDDKVYKMSRALAEIKKRFQKTVTQFINSILLAAGLF
                     TIEYPTKKEEEEFVRFKMRSRTHPERLPKLSLYSGESLLRSQSGHLESSIAETLKDEP
                     ESAPVSPVRKTTKIHTKAKVTSRGKAREGRSPTRWAALPSDCPLVLRKLMLKEDTRAG
                     CKCLVKAPLVSDVELERFLLAPRDPSQVLVFGIISSQNYTSTGQLQWLLNTLYNHQQR
                     GRGSPCIQCRYDSYRLLQYDLDSPLQEDPPLMVKKNSVVQGMILMFAGGKLIFGGRVL
                     NGYGLSKQNLLKQIFRSQQDYKMGYFLPDDYKFSVPNSVLSLEDSESVKKAESEDIQG
                     SSSSLALEDYVEKELSLEAEKTREPEVELHPLSRDSKITSWKKQASKK"
     exon            895..1035
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1155
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1288
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1570
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1723
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..1844
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            1845..1976
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            1977..2100
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            2101..2350
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            2351..2654
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            2655..2762
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            2763..2905
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            2906..3040
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
     exon            3041..3286
                     /gene="C3orf20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagttaaca caacctggag tagcccatgc catactgtgt ccttttaagt cagtaaattg
       61 aactaagtcg gttattcggc aagcagttcc tataaaaaac tacatggcta agatgtacac
      121 gttggataat tccatgccca tcttggcatt gcgaccagga gcttctgcat cccttgcttc
      181 caaagcgaac cagtgaaaca tctttttatt cttgcaggtt cttaatgatt gaccacaagc
      241 agatctttca ccctcggatc tctagctaca aaaggaacca ctggctcaat gacctgtaag
      301 ggccgtttca gcacatccat tctgtccatc tccaagcctt caccgtaggg aagaactttt
      361 gctctcagtc acctctcaga gagctctctt tatagctgaa ggtccctctc atgagttaca
      421 tcaagagtaa cctagaatta tatcagcaat acacagccat ggcccccaag ctactggccc
      481 gcatctccaa actcctcatg atctgccaga atgcaggcat ttctgtacca aaaggcatca
      541 gaaacatctt tgagttcact tgggaagagc tcatcagtga cccttcagtg cctaccccgt
      601 ccgacatctt gggcctggag gtcagctttg gagcccccct ggtggtgctc atggaaccca
      661 cctttgtgca ggtccccaca ctgaagaagc cactacctcc accaccacca gcaccaccac
      721 gtccagtgct gctggcaacc actggggcag ccaagcgctc caccctctct cccaccatgg
      781 cccgtcaggt gcgcacccac caggagaccc tgaacaggtt tcagcagcag tccatccacc
      841 tgctgacgga gctcctcaga ctgaagatga aggccatggt ggagtctatg tcggtgggtg
      901 ccaacccctt ggacatcacc aggcgctttg tggaggccag ccagctcctc cacctcaatg
      961 ccaaggagat ggccttcaac tgcctgatca gcacagccgg gagaagtggc tacagcagcg
     1021 gacagttgtg gaaagagtcc ctcgcaaaca tgtccgccat tggggtgaac tcgccttacc
     1081 agctgatcta ccactcttcc acagcctgtc tgagcttttc tctctctgct ggaaaagaag
     1141 ccaagaagaa aataggcaaa tctagaacta cagaagatgt cagcatgccg cccctgcatc
     1201 gaggagtggg aacccctgcc aacagcctgg agttcagcga cccctgccct gaggcccggg
     1261 agaagctgca ggagttgtgt cgccacatag aagctgaaag ggccacatgg aaagggagga
     1321 atatctccta ccccatgatc ttacgaaact acaaggcaaa gatgccctct catctaatgt
     1381 tggcccgcaa aggagactct cagaccccgg gtttacatta ccctcccact gcaggtgctc
     1441 agactctcag ccccacctct cacccatctt ctgccaacca tcatttcagt cagcattgtc
     1501 aagaggggaa ggcacccaag aaggccttca agtttcatta caccttctat gatggctcct
     1561 ccttcgttta ctatccctct ggaaacgtcg ctgtatgtca gatccccaca tgctgcagag
     1621 ggagaaccat cacctgcctc tttaatgaca tacctggatt ctccttgctg gccctattca
     1681 atactgaagg ccagggctgt gttcactaca acctaaaaac cagttgccca tatgtcttaa
     1741 tcttggatga ggaaggtggg accaccaatg accagcaggg ctatgtagtc cacaagtgga
     1801 gctggacttc caggacagag accctgcttt ccctggaata caaggtgaat gaggaaatga
     1861 aactaaaggt actgggacag gactccatca cagtcacctt cacctccctg aatgagacag
     1921 taacactcac tgtgtcggcc aacaattgtc cccatggaat ggcatatgac aaacggctga
     1981 accgcagaat cagcaacatg gacgacaagg tgtataagat gagccgagcc ctggctgaga
     2041 tcaagaagcg gtttcagaag acagtgactc agttcattaa ttctatcttg ctggccgcag
     2101 gtctgtttac cattgaatat cccaccaaaa aggaggagga agaatttgtt cggttcaaga
     2161 tgagatccag aactcatccc gagcggctcc ccaagctaag tttatactca ggagaaagtc
     2221 ttttacgatc tcagtcaggc cacctggaat cctcaattgc agagactttg aaggatgagc
     2281 ctgagtctgc tcctgtgagc ccagttcgga agaccaccaa aatccacacc aaagccaagg
     2341 tcacatccag agggaaggcc cgcgaggggc gcagccccac caggtgggcg gccttgccct
     2401 cagactgccc gctggtgctg cggaagctca tgctcaagga agacacccgt gctggctgca
     2461 agtgcctggt gaaggcgccc ctggtctctg acgtggagct ggagcgcttc ctgttggcgc
     2521 cccgagaccc cagccaagtg ctggtgtttg ggatcatctc aagccagaac tacaccagca
     2581 ctgggcagct ccagtggctg ctgaacactc tctacaacca ccagcagcgg ggccgtggct
     2641 ccccctgcat ccagtgccgg tatgactcct accgcctgct gcagtatgac ctggacagcc
     2701 ccctgcagga ggaccctccc ctgatggtga agaagaactc tgtggtgcag gggatgattc
     2761 tgatgtttgc cggggggaag ctcatttttg ggggccgtgt tttgaatgga tatggcctca
     2821 gcaagcagaa tctgctgaaa cagatcttcc ggtctcaaca ggattacaag atgggctact
     2881 tcctgccgga tgactacaaa ttcagtgttc ccaactctgt cctgagcctg gaggattctg
     2941 aatcagtcaa gaaagccgag tcagaagata tccaaggaag cagctcctca ttggccctgg
     3001 aagactatgt ggagaaggag ttatctctgg aggctgagaa gacaagagag cctgaagtgg
     3061 agctacatcc tctcagcagg gacagcaaga taactagttg gaagaagcag gcctccaaga
     3121 agtagcgcca tcctggcagc agccaagtga gccaggcccc ggcccggggt gctggggctt
     3181 cttgccagcc cagccctgcc tccccggtct cccaccctgt cctccaagct tctataataa
     3241 accagcgggc ctccagcatt ggggtgaggc tctggggaag gacaga
//
