LOCUS       NM_001080474            3052 bp    mRNA    linear   PRI 25-JUL-2022
DEFINITION  Homo sapiens chromosome 2 open reading frame 78 (C2orf78),
            transcript variant 1, mRNA.
ACCESSION   NM_001080474 XM_371500
VERSION     NM_001080474.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC092653.3 and AC136006.5.
            
            On May 20, 2021 this sequence version replaced NM_001080474.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000409561.2/ ENSP00000387124.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               AC092653.3         194316-194539
            225-974             AC136006.5         152598-153347
            975-3052            AC136006.5         154192-156269
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p13.1"
     gene            1..3052
                     /gene="C2orf78"
                     /gene_synonym="COG5373; hCG1989538"
                     /note="chromosome 2 open reading frame 78"
                     /db_xref="GeneID:388960"
                     /db_xref="HGNC:HGNC:34349"
     exon            1..224
                     /gene="C2orf78"
                     /gene_synonym="COG5373; hCG1989538"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..2896
                     /gene="C2orf78"
                     /gene_synonym="COG5373; hCG1989538"
                     /codon_start=1
                     /product="uncharacterized protein C2orf78"
                     /protein_id="NP_001073943.1"
                     /db_xref="CCDS:CCDS46338.1"
                     /db_xref="GeneID:388960"
                     /db_xref="HGNC:HGNC:34349"
                     /translation="MHWLASATQTSASIVSSSLLSAVDVSSSLTMSEYFQNTSLPGTA
                     NSRQFSLPVVSNAAFLTGSISNFSRASAPAISSAWLQPSASGTSFQPLMGSAYLYQHS
                     STTMLSGVTGQSHICTSAASYPGVFEWDSTASTVKKSSSLRDFTVTVIDQNTAVSSMS
                     MTAQYYKTSDTNTMVPLYPSLSASLVQGTLTQIPNQQGHNLSLPCQIGSQVYYYNQGT
                     LGPQLSCLQSYGSVSYTGYRASAHQPEMVMVLKEVQPTNVLPPVSTSGMYYSVSSQPI
                     TETSVQVMETSLGMDTSLGLQSPSQTFCLPQTPEFSKSFSSRNTQTLESNPSPELGDI
                     SITPVQSPTNLLTLSPAPSQEKNENENLDEIKTNLSKPLDVHQILIGNQDPPLLPVEI
                     PDIHPLLACIDPLGQEEQPGSENANLRNKSLSLEDQGIFENGIESSSDLADITTWVED
                     TYLPPIFSSLQDLDQPESPSAKKAKDTSAIKVNQVQEKSCVIKGHSDQVRKNKHKASE
                     PIQGAPKAKIQPKNPECLLEREVVVGSATVSNSASVNKAKHSSNKPHKAASSRISKTK
                     SHGQEKTKGNRKNSSKKSEESKQSGKKVKVEEKQTIPNMKRKKNQPELSQKTLKKPRS
                     SLGMHMLESVQVFHALGKKIDMKTGFSSSRTLGSSSNTQNRQPFPALKPWLDIQHEGK
                     GPEKIQVKAQKLDGSAEKECTSPSHSELPPPGKVKLIPLPFLTLDQPQARHVSRRPNP
                     LASRRPAVAYPARPDSTNSAQSNAVNPSRPAPTNTSLTGPATPAQPISAKATQPSSAN
                     PTQPTVPQSAASRPSAYKTSSCSSLQREPVSTAVTSLRSLPKPQNQFLIQDFSLQPRP
                     WRKPTVPEPVMSTPITEEQRPEREAMKRKAQQERENAAKYTSLGKVQFFIERERDMEI
                     AEYYGYTI"
     exon            225..974
                     /gene="C2orf78"
                     /gene_synonym="COG5373; hCG1989538"
                     /inference="alignment:Splign:2.1.0"
     exon            975..3052
                     /gene="C2orf78"
                     /gene_synonym="COG5373; hCG1989538"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3028..3033
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C2orf78"
                     /gene_synonym="COG5373; hCG1989538"
                     /note="hexamer: AATAAA"
     polyA_site      3052
                     /gene="C2orf78"
                     /gene_synonym="COG5373; hCG1989538"
                     /note="major polyA site"
ORIGIN      
        1 attctcccac caaaccgacc accacctggt agcatcttgg ggtttcctgg gcgtggcctg
       61 taaatttgta tcatcacaag gggccagtga ccagtaacca gtgaccagtg gccttcatac
      121 tggacacatg cactggttgg cttcagccac ccagacatcc gctagtatcg tctcttcttc
      181 ccttctatct gcagttgatg tttcttcttc tctgaccatg tcagaatatt tccaaaatac
      241 gtctttacct ggaactgcaa attctcggca gttctctctt cctgtggtga gcaatgcagc
      301 tttcttaaca ggaagcatct ccaacttctc cagagcctct gctccagcca tcagctcagc
      361 atggctacag ccatcagcct ctggcacctc cttccagcca ctcatgggca gtgcctacct
      421 ttaccaacat tctagcacaa ctatgttgtc tggggttact ggccagagcc atatctgtac
      481 ttcagctgcc tcttatccag gcgtttttga gtgggatagt acagcaagca cagtaaagaa
      541 gtcatcctca ctcagggact tcactgtgac tgtcattgat cagaacacag ctgtctcttc
      601 catgtctatg acagcccagt attataaaac ttcagatacc aatactatgg tccctctgta
      661 tccatcacta tctgccagcc ttgttcaggg gacactaact caaattccaa atcagcaggg
      721 ccataacctg tcacttccct gccagatagg aagccaggtc tattactata atcaaggcac
      781 actggggcct caactatcct gcctgcaatc ttatggctct gtgtcataca caggatatag
      841 ggcttctgcc catcaaccag aaatggtgat ggtgctgaag gaggttcagc ccacaaatgt
      901 cctaccacca gtctctactt ctgggatgta ttactctgtg tcttctcaac ccatcacaga
      961 aaccagtgtt caagtgatgg aaacttccct ggggatggat acttccctgg gattgcaatc
     1021 tccaagccag acattttgtc tgccacaaac tccagaattc tccaagtcct tcagtagcag
     1081 aaatacccag acacttgaga gtaacccatc acctgagctt ggggacattt caataactcc
     1141 agtccagagt cctactaatc tcttgacact gtctccagct ccaagccagg aaaaaaatga
     1201 gaatgagaat ttggatgaga ttaaaaccaa cctttcaaag cctctagatg tccaccagat
     1261 cctaatagga aatcaagatc ctccactact tcctgtagaa atccccgata ttcacccgct
     1321 tctggcctgc attgatcctc ttggccaaga ggagcagcct ggttctgaaa atgccaatct
     1381 aagaaataag agcctgagtc ttgaggacca agggatattt gaaaatggga ttgagtctag
     1441 cagtgatttg gcagacatca ctacatgggt ggaggatact tacctccccc cgatcttcag
     1501 ttccttacaa gatcttgacc aacctgaaag tccctcagca aagaaagcca aagataccag
     1561 tgccatcaag gtaaatcagg tgcaggaaaa gtcatgtgtc ataaagggtc actctgatca
     1621 agtcaggaag aacaagcata aagcttccga gcctatccag ggtgctccca aggccaaaat
     1681 ccagccaaag aacccagagt gcctattaga gagagaagtg gttgttggca gtgctacagt
     1741 cagtaacagc gcttctgtga acaaggccaa gcattctagc aacaaacctc acaaggctgc
     1801 atccagcagg atcagcaaaa ctaagagcca tgggcaggaa aagaccaaag ggaacagaaa
     1861 gaacagctcc aagaaatctg aagagagtaa gcagtcaggg aaaaaagtca aggtagaaga
     1921 gaagcaaacc attcccaata tgaaacggaa gaaaaatcaa cctgagctta gccaaaagac
     1981 ccttaaaaag ccccgaagct ccctaggcat gcacatgcta gagtccgtgc aagttttcca
     2041 tgcactcggg aaaaagatcg atatgaaaac tggattctct tcctccagga ccctgggaag
     2101 ctcaagcaac acccaaaacc gccagccatt cccagctctc aaaccatggc tggatatcca
     2161 acatgagggt aaaggcccgg agaaaattca agtcaaggcc cagaaactag atggtagtgc
     2221 tgaaaaagag tgtacatctc catcccactc tgagttgcca ccacctggga aggtcaagtt
     2281 gatacctttg ccctttctga ccctggacca acctcaagct cgacatgttt ctcggcggcc
     2341 aaaccctcta gcctcacgta ggcctgctgt ggcttaccct gctcgacctg attctactaa
     2401 ctcagctcaa tcgaatgcag tcaatccatc ccgaccagct cctaccaaca catctttgac
     2461 aggtcctgcc acaccagctc agccaatttc agccaaagca acccaaccca gttcagccaa
     2521 ccctacccag cctactgtcc ctcaatctgc tgcttctagg ccatcagcct acaaaacatc
     2581 atcttgttct tctctgcagc gggagcctgt ttccactgct gtgaccagtc tccggtcact
     2641 gcccaagcct caaaatcaat ttctaatcca agacttcagc ctccaacccc gtccatggag
     2701 gaaacccact gttcctgagc cagtaatgtc aacgcccatc acagaagagc agaggccaga
     2761 gcgtgaggcc atgaagagaa aggctcaaca agagcgtgag aatgctgcca aatacacctc
     2821 tttggggaaa gtgcagtttt tcattgaaag ggaaagagat atggaaattg ctgaatacta
     2881 tggctacaca atctaagagc tgagattgtt ggttttactt tggataccgc tggttttcca
     2941 catatataga tagatactaa tttatttatt ctgatatatt tttaaaacat aataaagaaa
     3001 tgtaatagaa ttgattaata gataagtaat aaagaggcct tttgagtttt ga
//
