LOCUS       NM_001144994            3629 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens chromosome 2 open reading frame 72 (C2orf72), mRNA.
ACCESSION   NM_001144994 XM_001129456 XM_001132119 XM_001715135
VERSION     NM_001144994.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3629)
  AUTHORS   Hillier,L.W., Graves,T.A., Fulton,R.S., Fulton,L.A., Pepin,K.H.,
            Minx,P., Wagner-McPherson,C., Layman,D., Wylie,K., Sekhon,M.,
            Becker,M.C., Fewell,G.A., Delehaunty,K.D., Miner,T.L., Nash,W.E.,
            Kremitzki,C., Oddy,L., Du,H., Sun,H., Bradshaw-Cordum,H., Ali,J.,
            Carter,J., Cordes,M., Harris,A., Isak,A., van Brunt,A., Nguyen,C.,
            Du,F., Courtney,L., Kalicki,J., Ozersky,P., Abbott,S.,
            Armstrong,J., Belter,E.A., Caruso,L., Cedroni,M., Cotton,M.,
            Davidson,T., Desai,A., Elliott,G., Erb,T., Fronick,C., Gaige,T.,
            Haakenson,W., Haglund,K., Holmes,A., Harkins,R., Kim,K.,
            Kruchowski,S.S., Strong,C.M., Grewal,N., Goyea,E., Hou,S., Levy,A.,
            Martinka,S., Mead,K., McLellan,M.D., Meyer,R., Randall-Maher,J.,
            Tomlinson,C., Dauphin-Kohlberg,S., Kozlowicz-Reilly,A., Shah,N.,
            Swearengen-Shahid,S., Snider,J., Strong,J.T., Thompson,J.,
            Yoakum,M., Leonard,S., Pearman,C., Trani,L., Radionenko,M.,
            Waligorski,J.E., Wang,C., Rock,S.M., Tin-Wollam,A.M., Maupin,R.,
            Latreille,P., Wendl,M.C., Yang,S.P., Pohl,C., Wallis,J.W.,
            Spieth,J., Bieri,T.A., Berkowicz,N., Nelson,J.O., Osborne,J.,
            Ding,L., Meyer,R., Sabo,A., Shotland,Y., Sinha,P., Wohldmann,P.E.,
            Cook,L.L., Hickenbotham,M.T., Eldred,J., Williams,D., Jones,T.A.,
            She,X., Ciccarelli,F.D., Izaurralde,E., Taylor,J., Schmutz,J.,
            Myers,R.M., Cox,D.R., Huang,X., McPherson,J.D., Mardis,E.R.,
            Clifton,S.W., Warren,W.C., Chinwalla,A.T., Eddy,S.R., Marra,M.A.,
            Ovcharenko,I., Furey,T.S., Miller,W., Eichler,E.E., Bork,P.,
            Suyama,M., Torrents,D., Waterston,R.H. and Wilson,R.K.
  TITLE     Generation and annotation of the DNA sequences of human chromosomes
            2 and 4
  JOURNAL   Nature 434 (7034), 724-731 (2005)
   PUBMED   15815621
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009407.8, DA141613.1, AF007149.1, AF070612.1, DB303203.1 and
            AV658788.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001144994.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.258699.1,
                                           SRR1803613.153293.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000373640.5/ ENSP00000362743.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-593               AC009407.8         23152-23744
            594-1145            DA141613.1         1-552
            1146-2279           AF007149.1         590-1723
            2280-3134           AF070612.1         767-1621
            3135-3609           DB303203.1         1-475               c
            3610-3624           AV658788.1         637-651
            3625-3629           AC009407.8         35344-35348
FEATURES             Location/Qualifiers
     source          1..3629
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q37.1"
     gene            1..3629
                     /gene="C2orf72"
                     /note="chromosome 2 open reading frame 72"
                     /db_xref="GeneID:257407"
                     /db_xref="HGNC:HGNC:27418"
     exon            1..677
                     /gene="C2orf72"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..931
                     /gene="C2orf72"
                     /codon_start=1
                     /product="uncharacterized protein C2orf72"
                     /protein_id="NP_001138466.1"
                     /db_xref="CCDS:CCDS46539.1"
                     /db_xref="GeneID:257407"
                     /db_xref="HGNC:HGNC:27418"
                     /translation="MERELEALAARLARPAEPPFQALVEAAGGRGQVLLVGELWEREQ
                     SRALLRDFARAVFPPEPGAAKPGGAAAEGAGPGAARGAQRAARAAGAAGAAAAAARAI
                     RSPLVFVLCRASSLAAREPRRRLREMLRDVRGRRRAGAALVGVLVAEAGPEDAVAPGL
                     RLLEALLRAVFGRQAGGPVQAAAYCPGLPASCLAVQAAACRALQAAGAGQPVEGAWER
                     PGLPGLLACFSWGPWSRRKNQDVAACRSSAQEDFQEPEEELPLTAIFPNGDCDDLGRG
                     SKACDGVVHTPAEPTGDSR"
     exon            678..791
                     /gene="C2orf72"
                     /inference="alignment:Splign:2.1.0"
     exon            792..3629
                     /gene="C2orf72"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2824..2829
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C2orf72"
                     /note="hexamer: ATTAAA"
     polyA_site      2848
                     /gene="C2orf72"
                     /note="major polyA site"
     regulatory      3585..3590
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C2orf72"
                     /note="hexamer: AATAAA"
     polyA_site      3629
                     /gene="C2orf72"
ORIGIN      
        1 gcgcccgggc cgcggcggcc gcagagggcg ggcggcggcc agcatggagc gcgagctgga
       61 ggcgctggcg gcccggcttg cgcgccctgc cgagccgccc ttccaggcgt tggtggaagc
      121 ggcggggggc cgcgggcagg tgctgctggt gggcgagctg tgggagcgcg aacagagccg
      181 cgcgctgctg cgggacttcg cacgggcggt gttcccgccg gagccaggcg cggccaagcc
      241 gggcggcgcg gcggcagagg gcgcggggcc cggggcggcg cgcggggcgc agagggcggc
      301 gagggcggct ggggcggcgg gggcggcggc ggcggcggcg cgcgccatcc gctcgccgct
      361 ggtcttcgtg ctgtgccgcg cgtcgtcgct ggccgcccgg gagccgcggc gccgcctgcg
      421 ggagatgctg cgggacgtgc gcggccggcg gcgggccggg gcggcgctgg tcggggtgct
      481 ggtggccgag gccgggccag aggacgcggt ggcgccgggg ctgcggctgc tggaggcgct
      541 gttgcgcgcc gtgttcggcc gccaggcggg ggggcccgtg caggcggccg cctactgccc
      601 cggcctcccg gcctcctgcc tggccgtcca ggcggccgcc tgcagggccc tgcaagccgc
      661 cggagccggg caaccagtgg aaggagcctg ggagaggcca ggcctccccg gactgctagc
      721 ctgcttttcc tggggtccct ggagccggag gaagaaccag gatgttgctg cctgcagaag
      781 ctcagctcag gaagacttcc aggaacctga ggaggagctg ccactaacag ccatatttcc
      841 caatggagac tgtgatgacc ttggaagggg gtcaaaagcc tgtgatggag tcgtacacac
      901 tcctgctgag cccaccggag actcaagatg aaggctggac ccttgcgctg tccctggctc
      961 taacctacag actggggcct ggctccgtct tactggcccc caggtctcca tggagactgc
     1021 agaaaccccc gcctgctgga ggcctgccac actcacagtt accagctaga cagtggggct
     1081 tactaagaca agcaggacct aaaacagtgt ctcccctggg aacctactcc ccacccagca
     1141 tttgctaagt ctgatcacag ggaggttatt ttgtctctct gtctcggttt ctctgagcca
     1201 ctgagacaga tggctgtccg ctttgaggct ctgcagagct gtggcacccc atggtgtgtc
     1261 tgcagtgttc tgggcacatg catgggcacc catcgttgag agtgcagctg ggaagaactc
     1321 tgaaccagaa gtcatcagag ctgaggcatg gccttgaaca tgtcactcag tctctggggc
     1381 ttctgtttca caaatgcatg agggggccac cagcccagtg gctttaaacc aggggcaggt
     1441 tgtccctcca ggcagcattg gaaatgtgtg tgtgttgagg gggtcacagt gactgtgggg
     1501 gcacccctgg catctagtgg gcatcccaca atgtgcagaa cagtctctga cagcaaagaa
     1561 ttggtccatt caatgccaat tgtagtacct ttgagacatt ctggctgagc caatgccttc
     1621 tccctgtcag agtcccccag agcagagagg gtcaggcttc cctggacctt ggctcccaga
     1681 gcaagccaaa ataaagacta cactgttgcc ttgggggctt gtcgggccag ggccaagacg
     1741 gtctgcgtgc tgcagggcca ggacagaaat agccacacat gccggtgaga acaaagagcc
     1801 tctttctttc tcatgttgac atcgactttc tgtgccaagt cctttgggta taaggatgct
     1861 agggaattcc tataggcacc aaacagaagg aaagctaggg gcttggacta ctgggtatag
     1921 gacttgctct agctctcagg tcctagccca agctcaatgc aaacacagcc cctccgggct
     1981 ctctgtttct gtgaggttct ggaatccctt cctctgtgtc cgtgagtctg acagaatcga
     2041 tgatgttccc ttagagctgg gaaatccatg tgtttattca cggagggaac tcaccattac
     2101 ctcccttgtc ttctttgcct gccttggaga aatccagagt cttcggaatg gcaaaggcag
     2161 ctcctggatt tccctggagg ggaggcacta gctgagggaa gtagctccct tcattcatga
     2221 tgcacagttt acgcagcaga cacacaactg cgcctactat ttgctcggtg ccctgcaagg
     2281 tgctgcctaa ctttgatttg ttatttcagc tctctccagg atagtgccaa atggtgcaat
     2341 gggaaacctg ttttgctggg gggctctaga tcactggctc cagaactccc ggctgccagg
     2401 gtagccccta cccccagccc cttgctcctg gacagcagtg ggtctcacct ttagcctctg
     2461 cccccagttc tggtctgacc caacagaggg gctctatgat attaagaagg ggcccttcct
     2521 gctctgtgcc tcaacctatt ctccataata gggagtctaa tcctattcct tccctgcctg
     2581 atgaggatgg tgtgaggatg aggaggacgg catctcattt ggggcttttt ggcagtgggc
     2641 ctcattttaa tcctgcaggg ctgcctgcca gtggatctat ccagctgctt ccttgtagcc
     2701 aagaatgagt tcaatgaatt gtgattcact gattttattg attttgtttt aaaacaggga
     2761 gactggtatt tttgaagctg ctatcatttt ctatttcttt attaatttct ttgtaatcat
     2821 cttattaaag ttttcttatt tagtgggaga gggagctttg tttaagtttg gaatttgcct
     2881 aaggcagaag ttataaggct tcataacctt ttgtatgtat tgccaatatt tgaaacttgg
     2941 gagattacgt ataaaaaata cctagttttc tgggtggagg atggggcatg ctgtcatctc
     3001 aagtctgctg cggctcaccc ccaccacctt taccccctcc cccgcccttc ccatccccca
     3061 ctgcacttca ctcatgtaag acgtctgccc ggtgctggtc caggcgggca tgtgagtttg
     3121 tagcctctgc tccaaaggat ggtttacaca ttattttttc attaccttca gtattcctgt
     3181 gaatggttca agagagaaag tcttcattta ctaagatttg ggttctgcct cccaagtgac
     3241 aatacggggc tgagatccct ctcagcttct ttgagatgtg gccaccataa gcatcatcgt
     3301 tgtagggaca gtctcattgc tgtcttctag cagacagaag agttaggtgc cagaaaggac
     3361 aatcttgatg gtgggtcccc tccctgaagg actttaagaa ggcataaagg ggttggggtg
     3421 gagggtggcg tgtgaaggag gaggcccttg attaggtcag tggtccctgg gagccatcgg
     3481 cgagaggcct ccagccgggt gacagtctgg gctctcgggt actaatcttt ctaatatggc
     3541 agtggttgtg gcacttctga cttgaattga taattctcat atctaataaa accaagaagt
     3601 acctcgttga tatcttatag aaaacaaaa
//
