LOCUS       NM_001394591            1560 bp    mRNA    linear   PRI 06-AUG-2024
DEFINITION  Homo sapiens C2 calcium dependent domain containing 4D (C2CD4D),
            transcript variant 2, mRNA.
ACCESSION   NM_001394591 XM_016999989
VERSION     NM_001394591.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL589765.19.
            
            On Apr 28, 2021 this sequence version replaced XM_016999989.2.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000694868.1/ ENSP00000511551.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               AL589765.19        162039-162195       c
            158-1560            AL589765.19        160193-161595       c
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.3"
     gene            1..1560
                     /gene="C2CD4D"
                     /gene_synonym="FAM148D"
                     /note="C2 calcium dependent domain containing 4D"
                     /db_xref="GeneID:100191040"
                     /db_xref="HGNC:HGNC:37210"
     exon            1..157
                     /gene="C2CD4D"
                     /gene_synonym="FAM148D"
                     /inference="alignment:Splign:2.1.0"
     exon            158..1560
                     /gene="C2CD4D"
                     /gene_synonym="FAM148D"
                     /inference="alignment:Splign:2.1.0"
     CDS             389..1450
                     /gene="C2CD4D"
                     /gene_synonym="FAM148D"
                     /note="family with sequence similarity 148, member D"
                     /codon_start=1
                     /product="C2 calcium-dependent domain-containing protein
                     4D"
                     /protein_id="NP_001381520.1"
                     /db_xref="CCDS:CCDS44224.1"
                     /db_xref="GeneID:100191040"
                     /db_xref="HGNC:HGNC:37210"
                     /translation="MWLLEKAGYKVGAAEPAARWAPSGLFSKRRAPGPPTSACPNVLT
                     PDRIPQFFIPPRLPDPGGAVPAARRHVAGRGLPATCSLPHLAGREGWAFLPESPHTRR
                     RESLFHGPPPAPAGGLPAAQSRLHVSAPDLRLCRAPDSDTASSPDSSPFGSPRPGLGR
                     RRVSRPHSLSPEKASSADTSPHSPRRAGPPTPPLFHLDFLCCQLRPTRESVLRLGPRG
                     GQLRLSTEYQAGPGRLRLRLVSAEGLPRPRSRPGSGGGGCCVVLRLRPRVRPREQQSR
                     VVKCSANPIFNEDFFFDGLGPPDLAARSLRAKVLDRGAGLRRDVLLGECETPLIALLP
                     PLGGGLGPGSSLAPTHLSL"
     regulatory      1538..1543
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C2CD4D"
                     /gene_synonym="FAM148D"
                     /note="hexamer: AATAAA"
     polyA_site      1560
                     /gene="C2CD4D"
                     /gene_synonym="FAM148D"
                     /note="major polyA site"
ORIGIN      
        1 agacgcggga tgcggtaggg ctgggaggcg cgggagctgg acggtcaggg ctactggggg
       61 tgggattctg tgtccccggg aggtgcgtct ccttggacca gcccagggtg tcctgaggtc
      121 agcagccagg tgtgtcccct ggctgccagg agcagaaccc cccagactgc gccgcccttt
      181 ctttttctgc tcaaataggg gtccgcgctc ccagtgggtc cggagaccgg ggcgcggtgg
      241 ctgaccgccc ggtgtacgcc agcatcactc acctctgact cctctgcgct cctcgcccag
      301 ccccgctccg ccgagcactc ccatctgaga cgggatttgg accctctcgg ccctgcggaa
      361 ttcggaattc cattacccca cccaccgcat gtggctcttg gaaaaagctg gctataaggt
      421 gggggccgcg gagcctgcgg cccgttgggc gccttccggc ctgttctcca agcgtcgcgc
      481 cccgggcccg cccacaagcg cctgccccaa cgtcctcacc ccggatcgca tcccgcagtt
      541 cttcatcccg cctcggctcc cggacccggg cggcgcagtg cccgcggccc ggcggcacgt
      601 ggcggggcgc ggcctccccg cgacctgctc gctgcctcac ctggcgggcc gcgaaggctg
      661 ggccttcctg cccgagagcc cgcacacgcg ccggcgggaa tccctgttcc acgggccgcc
      721 acctgccccg gccgggggac tccccgcggc gcagtcccgg ctgcacgtct ccgccccgga
      781 cctgcgcctc tgccgggccc ccgacagcga cacggcctcg tcgccggact cgtcgccctt
      841 cggctccccg cggccaggcc tgggccggcg ccgggtgtcc aggcctcact ctctgtcccc
      901 agaaaaagcg agctcggccg ataccagccc gcactcgccg cgccgcgccg ggccgcccac
      961 gccgccgctc ttccacctgg acttcctgtg ctgccagctg cggcccacgc gcgagagcgt
     1021 gctgcgcctg gggccccgcg gcgggcagct gcggctctcc accgaatatc aggccgggcc
     1081 cgggcggctg cggctgcgcc tagtgagcgc cgagggcctg ccccggccgc ggtcccgccc
     1141 cgggagcggc ggcggcggct gctgtgtggt gctgaggctg cggccccgcg tccggccgcg
     1201 ggagcagcag agccgcgtgg tcaagtgcag cgccaacccc atcttcaacg aggatttctt
     1261 tttcgacggg ctcggccccc cggacctggc cgcccgcagc ctgagagcca aggtgctaga
     1321 caggggcgcg ggacttcgca gggatgtgct gctgggggag tgcgagacgc ccctcattgc
     1381 gctgctgccc ccgctgggtg ggggactagg tcccgggtca tccctggcgc ccacccatct
     1441 cagcctgtag cctgagcccc tggcttcctc aggacgtctc cactgtgtct gcagtccaca
     1501 ttctttccac cctgcccggc ttgtatttat ttttgctaat aaaatgtccc cttgtcctta
//
