LOCUS       NM_001010859            1378 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens chromosome 22 open reading frame 42 (C22orf42), mRNA.
ACCESSION   NM_001010859 XM_086894
VERSION     NM_001010859.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1378)
  AUTHORS   Sivertsson,A., Lindstrom,E., Oksvold,P., Katona,B., Hikmet,F.,
            Vuu,J., Gustavsson,J., Sjostedt,E., von Feilitzen,K., Kampf,C.,
            Schwenk,J.M., Uhlen,M. and Lindskog,C.
  TITLE     Enhanced Validation of Antibodies Enables the Discovery of Missing
            Proteins
  JOURNAL   J Proteome Res 19 (12), 4766-4781 (2020)
   PUBMED   33170010
REFERENCE   2  (bases 1 to 1378)
  AUTHORS   Takamitsu,E., Otsuka,M., Haebara,T., Yano,M., Matsuzaki,K.,
            Kobuchi,H., Moriya,K. and Utsumi,T.
  TITLE     Identification of Human N-Myristoylated Proteins from Human
            Complementary DNA Resources by Cell-Free and Cellular Metabolic
            Labeling Analyses
  JOURNAL   PLoS One 10 (8), e0136360 (2015)
   PUBMED   26308446
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1378)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL008723.8, BU072847.1, CR456485.1 and CK818305.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001010859.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.121276.1, CR456485.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142586
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000382097.4/ ENSP00000371529.3
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AL008723.8         2149-2159           c
            12-47               BU072847.1         7-42
            48-852              CR456485.1         1-805
            853-1378            CK818305.1         47-572
FEATURES             Location/Qualifiers
     source          1..1378
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q12.3"
     gene            1..1378
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /note="chromosome 22 open reading frame 42"
                     /db_xref="GeneID:150297"
                     /db_xref="HGNC:HGNC:27160"
     exon            1..320
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..844
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /codon_start=1
                     /product="uncharacterized protein C22orf42"
                     /protein_id="NP_001010859.1"
                     /db_xref="CCDS:CCDS33639.1"
                     /db_xref="GeneID:150297"
                     /db_xref="HGNC:HGNC:27160"
                     /translation="MGSKLTCCLGPSGGLNCDCCRPDVGPCHECEIPETVAATAPAST
                     TAKPAKLDLKAKKAQLMQYLSLPKTPKMLKMSKGLDARSKRWLKIIWRRHGIWPLENI
                     GPTEDVQASAHGGVEENMTSDIEIPEAKHDHRPTEDVQVSAHGGVEENITSDIEISEA
                     KHDHHLVEDLSESLSVCLEDFMTSDLSESLSVSLEDFMTSGLSESLSVSLEDLMTPEM
                     AKERYEDYLCWVKMARSRLNEPISSQVLGLLRL"
     exon            321..395
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     exon            396..460
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     exon            461..488
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     exon            489..553
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     exon            554..581
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     exon            582..742
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     exon            743..770
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     exon            771..1378
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1358..1363
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /note="hexamer: AATAAA"
     polyA_site      1378
                     /gene="C22orf42"
                     /gene_synonym="dJ90G24.6"
                     /note="major polyA site"
ORIGIN      
        1 agtcggtagc tggccgtaga aggaggagga gctccgacta cattctgtcc ttgtgcctct
       61 tggacttttt tgtgtgttta ggtgcccaat ggggagcaaa ctgacttgct gcctgggccc
      121 cagcgggggc ctcaactgtg actgctgcag gccagatgtg ggaccctgcc atgagtgtga
      181 gattcctgag actgtggcag ccacagcacc agcatccacc actgcaaagc ctgccaaatt
      241 ggatttgaaa gctaagaagg cccaactcat gcagtacctc agcctcccga agacgccgaa
      301 gatgctgaag atgtccaaag gtttggacgc ccgctccaag cgctggttaa aaataatatg
      361 gagacggcac gggatttggc ctctagaaaa tataggtccc actgaagatg tgcaggcgtc
      421 tgcacacggc ggtgtggagg agaatatgac atcagatatt gaaatacctg aggccaagca
      481 cgaccaccgt cccactgaag atgtgcaggt gtctgcacac ggcggtgtgg aggagaatat
      541 aacgtcagat attgaaatat ctgaggccaa gcacgaccac catttggtcg aagatctcag
      601 tgaaagccta tctgtctgtc ttgaagactt catgacatcg gatctcagtg aaagcctatc
      661 tgtctctctt gaagacttca tgacatcagg tctcagtgaa agcctatctg tctctcttga
      721 agacctcatg acaccggaga tggcaaagga gagatatgaa gattacctct gctgggttaa
      781 gatggcacgg tctcggctca atgaacccat cagcagccag gttctaggac ttctccggct
      841 ttagtgttcc aagtagctgg gattacagac gcctgccatc acgcccagct caaatcattt
      901 tatgaatgca tatttccatc tgggtgaaaa aaaaatcaca agcctctctc tcttcctact
      961 gagcacctgt gaacagtgac ctgcagtttg tggctgcagc cagtcctctt gcagcctggt
     1021 gttcttacat ttcattctga ggctcacatt ctcagtcacc atgcagaaga acacccgccc
     1081 catcctgggt cattacagag tgggtcaatc catctgctgc atctgaagag ctgggtccag
     1141 cttctacagt gaatccatat atttctgtat ttcctggata aggaagagca aaggagctga
     1201 gctggtggag gaagaagaac taatattaac tgactcctta ttttgtgcta gtactgtgct
     1261 agttacatat tttatctcat gtaattctta ccaaactgta agggggtttc ggagtgatgg
     1321 agacaatatt gatgttatct ccattttagg gtgagaaaat aaaggctcag aaatgtta
//
