LOCUS       NM_153269               1576 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens chromosome 20 open reading frame 96 (C20orf96),
            transcript variant 1, mRNA.
ACCESSION   NM_153269
VERSION     NM_153269.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1576)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 1576)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   3  (bases 1 to 1576)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB226405.1, AK097394.1, EL734555.1, BC134417.1, DB320878.1 and
            AA921838.1.
            
            On Nov 23, 2018 this sequence version replaced NM_153269.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK097394.1, SRR3476690.11310.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000360321.7/ ENSP00000353470.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 DB226405.1         29-29
            2-448               AK097394.1         1-447
            449-919             EL734555.1         150-620
            920-1274            BC134417.1         906-1260
            1275-1575           DB320878.1         1-301               c
            1576-1576           AA921838.1         8-8                 c
FEATURES             Location/Qualifiers
     source          1..1576
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20p13"
     gene            1..1576
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /note="chromosome 20 open reading frame 96"
                     /db_xref="GeneID:140680"
                     /db_xref="HGNC:HGNC:16227"
     exon            1..160
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..1232
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C20orf96"
                     /codon_start=1
                     /product="uncharacterized protein C20orf96 isoform 1"
                     /protein_id="NP_695001.2"
                     /db_xref="CCDS:CCDS12994.1"
                     /db_xref="GeneID:140680"
                     /db_xref="HGNC:HGNC:16227"
                     /translation="MAHVLQKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQ
                     QANSLHTSKMKTLTRVQPVFHFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWLMK
                     TSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI
                     LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHE
                     YSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAE
                     TQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVI
                     FEDVLLRRPKCTPDMDVILNIPVEEPLPF"
     exon            161..209
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            210..327
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            328..446
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            447..605
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            606..705
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            706..863
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            864..965
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1052
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1171
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1576
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1554..1559
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /note="hexamer: AATAAA"
     polyA_site      1576
                     /gene="C20orf96"
                     /gene_synonym="dJ1103G7.2"
                     /note="major polyA site"
ORIGIN      
        1 gaaagcatcg ggtctcggga cttctgagtg gcctgggtta ccgcgcgatc tacactgaga
       61 caaggaagtt ggaaaagccg agtagttata ccagaagatc agggtctcac agactcgcaa
      121 cttctcttcc attttcccca atggcgcatg tcttacaaaa acccaagcac tctgggactc
      181 actccatagt ccaggagttc caggttccgg attatgttcc atggcagcag tccaagcagg
      241 aaaccaagcc atctactctg cctccagtcc aacaagccaa cagccttcat acaagcaaaa
      301 tgaagacttt gactagggtc caaccagtgt ttcacttcaa gcccactacg gtggtgacaa
      361 gctgccagcc gaagaatcca agagaactac atagaaggcg gaagttggac cctgggaaga
      421 tgcatgccaa aatctggtta atgaagacct cgctcaggag cgggagggcc gctctgcgag
      481 agctccgaag ccgtgagaac ttcctcagca agctcaaccg ggagctgatc gagaccatcc
      541 aggagatgga gaacagcacg accctgcacg tgcgggccct gctgcagcag caggacaccc
      601 tggcgaccat catcgacatc ttggagtact caaacaagaa gaggctgcag caattgaaat
      661 ctgagcttca ggagtgggaa gaaaagaaga aatgcaagat gagctatctt gagcagcagg
      721 cagagcagct gaatgccaag attgagaaga cccaggagga agtgaacttc ctgagcactt
      781 acatggacca tgagtattcc atcaagtctg tccagatctc cactcttatg cgccagctgc
      841 agcaggttaa ggacagccag caggatgagc tggatgacct cggtgagatg cgcagaaagg
      901 tcctggaatc cttgtctgac aagattcaga agaagaagaa aaaaattctg agttctgtgg
      961 tggcggaaac ccagcgtccc tatgaagagg ctctcctaca gaagatgtgg gaaagccagg
     1021 acttcctgaa atgcatgcaa aggttcagag aaattattga ccagtttgag gagaacatgc
     1081 ctgtattaag ggccgaggtg gaagagctcc aagcccagac ccgggaaccc cgagaggtca
     1141 tatttgagga tgttctgctt cggagaccca agtgcacccc agacatggat gtcatcctca
     1201 acattcctgt ggaagagcca ctacccttct agatggcagt gccatgggcc gccctcccct
     1261 cctgctctct tcccagcacc tggagccttg gatcatttac ttccaggacc ggatctccat
     1321 tcagaccctg atctacagtc tccctgctcc ctctgccctt cctccctctt tctttccctc
     1381 cctccctccc tcccttcttc cccccttccc ttccctcctc cttccttcct cctctccctc
     1441 cctccctcct ttctttcttc ctgtggtttt ttcctctctt cttcccttct ttctggttgg
     1501 tgctgctggg ccaggtggga atttctgatt aaatctgcta ttcctttttt accaataaag
     1561 ctggatttac atttgc
//
