LOCUS       NM_080825                522 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens chromosome 20 open reading frame 144 (C20orf144),
            mRNA.
ACCESSION   NM_080825
VERSION     NM_080825.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 522)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX378327.2 and DQ080434.1.
            
            On Nov 22, 2018 this sequence version replaced NM_080825.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX378327.2, DQ080434.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375222.4/ ENSP00000364370.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 BX378327.2         42-50
            10-522              DQ080434.1         53-565
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q11.22"
     gene            1..522
                     /gene="C20orf144"
                     /gene_synonym="dJ63M2.6"
                     /note="chromosome 20 open reading frame 144"
                     /db_xref="GeneID:128864"
                     /db_xref="HGNC:HGNC:16137"
     exon            1..145
                     /gene="C20orf144"
                     /gene_synonym="dJ63M2.6"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..481
                     /gene="C20orf144"
                     /gene_synonym="dJ63M2.6"
                     /note="bclt; bcl-2-like protein from testis"
                     /codon_start=1
                     /product="uncharacterized protein C20orf144"
                     /protein_id="NP_543015.1"
                     /db_xref="CCDS:CCDS13223.1"
                     /db_xref="GeneID:128864"
                     /db_xref="HGNC:HGNC:16137"
                     /translation="MGNYSSHKRTKAPKQARKERPADMDKAWWKSFLNHLTRKKPATR
                     IVLILPLDKRQPLANAGQRIDYASGAGLGSPAAPRLRGAGEGSEREPRMPVLLLLRRQ
                     EARRPEEGGARAALSWPRLLSRFRSPGKAPREAGPAEEQPRKRCRCPRPQL"
     exon            146..522
                     /gene="C20orf144"
                     /gene_synonym="dJ63M2.6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      504..509
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C20orf144"
                     /gene_synonym="dJ63M2.6"
                     /note="hexamer: AATAAA"
     polyA_site      522
                     /gene="C20orf144"
                     /gene_synonym="dJ63M2.6"
                     /note="major polyA site"
ORIGIN      
        1 agtggtgacc agccctgcca tgggaaacta tagttcccac aaaaggacca aagcacccaa
       61 gcaggcccgc aaggagaggc cggctgacat ggacaaggcc tggtggaaat cgttcctcaa
      121 ccacctcact cggaagaagc cggctaccag gatcgtgctg attctccccc tggacaagcg
      181 gcagccgctg gccaacgctg ggcaacggat tgactacgcg tccggcgctg ggctgggctc
      241 cccggcggca cccagattgc gcggagcggg cgaaggtagc gagcgcgagc cgaggatgcc
      301 ggtactgctg ctgctgcggc ggcaagaggc gcggcggccg gaagagggcg gggccagggc
      361 agctctgagc tggccgcggc tgctctcgcg cttccggtcc ccggggaagg ctccccgcga
      421 agccggcccc gccgaggagc agccgcgcaa acggtgccgc tgccctcgcc cgcagcttta
      481 aacgcttggc ccggaccccg cccaataaag agtgcgtggc aa
//
