LOCUS       NM_182517               1486 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens chromosome 1 open reading frame 210 (C1orf210),
            transcript variant 1, mRNA.
ACCESSION   NM_182517
VERSION     NM_182517.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1486)
  AUTHORS   Aturaliya,R.N., Kerr,M.C. and Teasdale,R.D.
  TITLE     A Novel Type III Endosome Transmembrane Protein, TEMP
  JOURNAL   Cells 1 (4), 1029-1044 (2012)
   PUBMED   24710541
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1486)
  AUTHORS   Orvedahl,A., Sumpter,R. Jr., Xiao,G., Ng,A., Zou,Z., Tang,Y.,
            Narimatsu,M., Gilpin,C., Sun,Q., Roth,M., Forst,C.V., Wrana,J.L.,
            Zhang,Y.E., Luby-Phelps,K., Xavier,R.J., Xie,Y. and Levine,B.
  TITLE     Image-based genome-wide siRNA screen identifies selective autophagy
            factors
  JOURNAL   Nature 480 (7375), 113-117 (2011)
   PUBMED   22020285
REFERENCE   3  (bases 1 to 1486)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093420.2, BM784450.1, BC041633.1 and BM273035.1.
            
            On May 17, 2019 this sequence version replaced NM_182517.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DRR138523.432833.1, BC041633.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2147920, SAMEA2150585
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000523677.6/ ENSP00000430918.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC093420.2         100490-100491       c
            3-13                BM784450.1         1-11
            14-901              BC041633.1         1-888
            902-902             AC093420.2         97371-97371         c
            903-982             BC041633.1         890-969
            983-1245            BM273035.1         235-497             c
            1246-1480           BC041633.1         1234-1468
            1481-1486           AC093420.2         96787-96792         c
FEATURES             Location/Qualifiers
     source          1..1486
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.2"
     gene            1..1486
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /note="chromosome 1 open reading frame 210"
                     /db_xref="GeneID:149466"
                     /db_xref="HGNC:HGNC:28755"
                     /db_xref="MIM:620582"
     exon            1..138
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /inference="alignment:Splign:2.1.0"
     exon            139..255
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..578
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /codon_start=1
                     /product="type III endosome membrane protein TEMP"
                     /protein_id="NP_872323.1"
                     /db_xref="CCDS:CCDS481.1"
                     /db_xref="GeneID:149466"
                     /db_xref="HGNC:HGNC:28755"
                     /db_xref="MIM:620582"
                     /translation="MNETNKTLVGPSELPTASAVAPGPGTGARAWPVLVGFVLGAVVL
                     SLLIALAAKCHLCRRYHASYRHRPLPETGRGGRPQVAEDEDDDGFIEDNYIQPGTGEL
                     GTEGSRDHFSL"
     exon            256..1486
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      802..807
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /note="hexamer: AACAAA"
     polyA_site      821
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /note="major polyA site"
     regulatory      1452..1457
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /note="hexamer: AATAAA"
     polyA_site      1486
                     /gene="C1orf210"
                     /gene_synonym="TEMP"
                     /note="major polyA site"
ORIGIN      
        1 actccgcgga ttgtgcacag ttcttgaagg tgggaacaga agagaaggcc cgggggggcc
       61 ggggaggggg tacccaggct ctgcacagta cccaaggggc ttctggcagc aggaaggaag
      121 ctacacatca gagttgggga cttgtgccct ggggctgcct ggcatctggg ggcctcctca
      181 gagccagggc tctttctggt tgaggctgag actcactggt gtcatcaggc ccctccatga
      241 atgagacaaa caaaacactt gttgggcctt cggagctccc cacagcgtct gctgtggccc
      301 ctggcccagg cactggggct cgggcatggc ctgtgctggt aggatttgtg ctgggggctg
      361 tggtcctctc gctcctcatt gcacttgctg ccaaatgcca cctctgccgc cgataccatg
      421 ccagctaccg gcaccgccca ctgcctgaga caggaagggg aggccgccca caggtggctg
      481 aagatgagga tgatgatggc ttcatcgagg acaattacat tcagcctggg actggcgagc
      541 tggggacaga gggtagcagg gaccacttct ccctctgagc tcccatcttt agaccctccc
      601 cactccctcc atgcctgaca gcttaaggac agtggttatg acatgggggc cttgaacctc
      661 agggacagag gtggctgggg cttaaaggtt ggccagggat ggagtaaacc ccacttccct
      721 gacactagcc agcaaagtga caatgaccct ctcttgctca ataactctca actgttccct
      781 gctgttctca ggataaagcc aaacaaaggc ttgagtgtgg acataaggcc ctctgtgatc
      841 atgcctctcg gcctcttggt ttcttttctt gccttcccct actttactgt cgaaatcaat
      901 gttattctcc ctcccaccac ttcccatgca gtttccccag gcacctttgc tcacattggt
      961 ccccctgcct acgctactct tctcctaaat cctctatgac tgtgatggcc tgcctacctg
     1021 ccagcatttc aaatatgccc agatggtaac atttgtgcag gtgaaaacca gtgccaagct
     1081 tccttttttt ttttttcctg agacggagtc tcactctgtt gcccaggctg gagtgcaatg
     1141 gcacatcttg gctcactgca acctccgcct cctgggttca agcgattctc ctgcttcagc
     1201 ctcctgagta gctgggatta caggcatccg ccaccacgcc cagctaattt ttatattttt
     1261 agtagagacg aggtttcgcc atattggcca ggatggtctc gaactcttga cctcaggtag
     1321 tccgccttcc tcggcctccc aaagtgctgg gattacaggc gtgagccacc atgcccggcc
     1381 agcttcttaa tgaaatattt tcctataaat aaagtgggta atccggttat aatatgtttt
     1441 tcacaggaat taataaatct attttcattt tgaataaaaa taaaaa
//
