LOCUS       NM_032800               3726 bp    mRNA    linear   PRI 14-FEB-2024
DEFINITION  Homo sapiens chromosome 1 open reading frame 198 (C1orf198),
            transcript variant 1, mRNA.
ACCESSION   NM_032800 NM_031428
VERSION     NM_032800.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3726)
  AUTHORS   Gevaert,K., Goethals,M., Martens,L., Van Damme,J., Staes,A.,
            Thomas,G.R. and Vandekerckhove,J.
  TITLE     Exploring proteomes and analyzing protein processing by mass
            spectrometric identification of sorted N-terminal peptides
  JOURNAL   Nat Biotechnol 21 (5), 566-569 (2003)
   PUBMED   12665801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL118511.25.
            
            On Jul 29, 2019 this sequence version replaced NM_032800.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.76004.1,
                                           SRR1803616.194260.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000366663.10/ ENSP00000355623.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-342               AL118511.25        61397-61738         c
            343-393             AL118511.25        48885-48935         c
            394-936             AL118511.25        36571-37113         c
            937-3726            AL118511.25        30336-33125         c
FEATURES             Location/Qualifiers
     source          1..3726
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q42.2"
     gene            1..3726
                     /gene="C1orf198"
                     /note="chromosome 1 open reading frame 198"
                     /db_xref="GeneID:84886"
                     /db_xref="HGNC:HGNC:25900"
     exon            1..342
                     /gene="C1orf198"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..993
                     /gene="C1orf198"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C1orf198"
                     /codon_start=1
                     /product="uncharacterized protein C1orf198 isoform 1"
                     /protein_id="NP_116189.1"
                     /db_xref="CCDS:CCDS1587.1"
                     /db_xref="GeneID:84886"
                     /db_xref="HGNC:HGNC:25900"
                     /translation="MASMAAAIAASRSAVMSGNRPLDDRERKRFTYFSSLSPMARKIM
                     QDKEKIREKYGPEWARLPPAQQDEIIDRCLVGPRAPAPRDPGDSEELTRFPGLRGPTG
                     QKVVRFGDEDLTWQDEHSAPFSWETKSQMEFSISALSIQEPSNGTAASEPRPLSKASQ
                     GSQALKSSQGSRSSSLDALGPTRKEEEASFWKINAERSRGEGPEAEFQSLTPSQIKSM
                     EKGEKVLPPCYRQEPAPKDREAKVERPSTLRQEQRPLPNVSTERERPQPVQAFSSALH
                     EAAPSQLEGKLPSPDVRQDDGEDTLFSEPKFAQVSSSNVVLKTGFDFLDNW"
     exon            343..393
                     /gene="C1orf198"
                     /inference="alignment:Splign:2.1.0"
     exon            394..936
                     /gene="C1orf198"
                     /inference="alignment:Splign:2.1.0"
     exon            937..3726
                     /gene="C1orf198"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3703..3708
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1orf198"
                     /note="hexamer: AATAAA"
     polyA_site      3726
                     /gene="C1orf198"
                     /note="major polyA site"
ORIGIN      
        1 aggccgggca tggcgtccat ggcggcggcg atcgcggctt cgcgctcggc ggtcatgagc
       61 gggaaccggc ctctggacga ccgggagcga aagcgcttca cttacttctc gtcgctgagc
      121 cccatggcca ggaagatcat gcaggacaag gagaagatcc gcgagaagta cgggcccgag
      181 tgggcgcggc tgccgcccgc gcagcaggac gagatcatcg accggtgcct ggtggggccg
      241 cgcgccccgg cgccccgaga ccccggggac tcggaggagc tcacgcgctt ccccggcttg
      301 cgcgggccca cgggccagaa ggtggtgcgc ttcggggacg aggatctaac ttggcaagat
      361 gagcactctg cccctttctc ctgggaaaca aagagtcaga tggagttcag tatctccgcc
      421 ctatccatcc aggagccgag caacggcacc gccgccagcg agcccagacc actgtccaaa
      481 gcttcccagg gctcccaggc cctcaagtcc tcccaaggca gcaggtcctc cagcctggac
      541 gccctgggcc ccaccaggaa ggaggaggaa gcgtcattct ggaagatcaa tgctgagcgg
      601 tcccgagggg aggggcctga ggccgagttc cagtcgctga cccctagcca gatcaagtcc
      661 atggagaagg gggaaaaggt cttgcctccc tgctaccggc aggaacctgc cccgaaggac
      721 agggaggcca aggtggaaag gcccagcacc ctccgtcagg agcagcgtcc tcttcccaac
      781 gtgagcaccg aacgtgagag accccagcct gtccaggcct tcagcagtgc actgcacgag
      841 gctgccccct cccagctcga ggggaagctg ccatctcctg atgtcaggca ggacgatggg
      901 gaagacaccc tgttctcgga acccaagttt gcacaggtca gctcaagtaa tgtcgtcttg
      961 aagacgggat ttgattttct ggacaattgg taaaatgtat tagaaaaata caatgaagaa
     1021 ccctaaaatg ttttccaaag tggtgtggtg gaggaggata aaaagggcca ccttttccta
     1081 tgtattttac tggtttcttg acactctttt cttaatcatt tggaaactgg tcaatattgc
     1141 cagatttttt tcttttttgg tagaaccaga tatatatgct attttcagtg atttgataac
     1201 agaagttttc catttggaat ttttaaggtc tgttaataat tcaggagatc ttgtaaataa
     1261 aacttctgtt cccagctcca cccaactttc cccctcctca aaggatgtgt ttcaaccatg
     1321 tcacaaaaat catataagtg atttccatct ccttctccat tattccccct cccccctccg
     1381 ctttttaccg tatgggttcc ttttggtggg tgattgaggg tgatgttatc agccatgaca
     1441 tcagcatgct ggctgtgacc ccggaaagac tggcccccag cgacgttctc agccagcgct
     1501 cgcagctgtc cggggcttct ctggcagaag ccatgtctct cacatcatgt gccagcctcc
     1561 accctcacgc catttccagg gaacagactg cgggtatgta gcagtgtagt ctttaacctg
     1621 ctctgataca tattcagagt atggattgtt gtttaaaaag agttgcatgt ttaaagagtt
     1681 ttgtactagc ttttcattat tttgtatcta gattatcaac aatggggcta ccactttcct
     1741 tggttttata tccatttcct cttggaagtt cttgttgctt atgtgacctg ttggttgttc
     1801 cccggactgg gcacctacag gagtcagggc agacggcaga tgtggctgga ggtcagggct
     1861 cttctgctta gttgtgttag agtcttccag catgggactg atgggagcag tgggcattct
     1921 ttatcccaag ggctagccag gttgcgtcat gacggacctt ccccagccct gaccaccacc
     1981 agaagtggaa gagtggagtt tgcggtcaac tcagcagtgc ccatggagac ctgcgtggtg
     2041 tcagagcagc agtatctctt ggagctggtg cagacaccaa ggctgcccag tggtacaacg
     2101 tggtccacct cccctaggga agctgctgca ctcagaggct gtcctgccca gtggcccctg
     2161 agccgtgtga gcctgcagga ggcgtctgag cagagcctca agcccggtat ggcgccatct
     2221 ccatgttgcc atcactgcgt tctcacctga agccttaatc tttgcgacac ctgccagtga
     2281 gcgctcggtt tcaataccaa agtgtgtctt cttctttttt tttttttttt aaatgcctgt
     2341 ttcataggac cttctgaaat gatttccaga atattttatc tggctccaaa ataaagcaca
     2401 tagcaactca cctcaacccc tcatcatctc caggaaagtt tctgccaaag ctgtggcata
     2461 gccaactttt gatttggttc ttgccaattg ttttatgtcc ctaaacctca tttggatcct
     2521 tggggtatag ttttatcttt ctgcttcagt gatttactgt aacttttcaa atattggttc
     2581 tttctgtacc atttaagtat agttgatata tgtgaggcaa aaaaaggttt cagcatggtg
     2641 gtgagggaaa aaggagctta gaaatcccag ttggcacagc ctgggcaagc gccagctccc
     2701 ctcagggcta acggcactgt tcacacaggg atcctcagaa tcagcggcca cctgcctcca
     2761 ccttctgcct ggagggcatg gggctgttgt agaacctatg gtagcaaatg tatatgtatg
     2821 agtttgtatt ctgtagtgtt ggtgtagcac agaagaaaga cctgtgtcct agagagtagg
     2881 ccaaggtgat ctgcctcttc tattgggaga aattctaatt tctttcccac tttctcaaca
     2941 agcccaatat tccctccaag ttcttcttgg tgctgagggc tgtaggaatt attgaaagct
     3001 tctgcctcac ttagtatcgt ctggggccca gcacccagca ataactctaa taatgtttct
     3061 taatggtata gcctcctgag attaaatgta aaatcaaaaa ttaggaaatc ttggagggag
     3121 tcctcaagtt gtattgcttt gctgtgcttt tggaagaagg gacgacctgg aggacacagg
     3181 ctcctgtgtg ggtcttcatc ctgcctgacc ggcagatctt cctctacacc ttgggcaaag
     3241 tctatgcgaa gatggtttct tagctctcca tttgccatga ttttcctccc attcatcatg
     3301 agggagtttc tcaaaccagg agtttatatt tattttttag aaaatacaca cttttcagga
     3361 gaaacctgag catgattttg gattctccac ctccccccag tctctgcacc tgggattcag
     3421 ctcaaggatt cagtgtcttc atttttacaa aagttccccc aagaaatcag caaccagcct
     3481 ctgtttcatc tgggagcccc tcccttggcc ccctgggttt gggggtgctg ccctactggg
     3541 aacagcgggg gtctgtcacc cgtctgagcc gcacccccct gtgtggattt caggaagagc
     3601 ctccctttct ttgcgtctcc ctttctttaa ttaacatttt caaaagtaat aaattcttac
     3661 tgacgacttg taacttagtc atattttata cttgtagcct ttaataaagc catttaaaaa
     3721 atgcta
//
