LOCUS       NM_001300834             840 bp    mRNA    linear   PRI 12-FEB-2024
DEFINITION  Homo sapiens chromosome 1 open reading frame 162 (C1orf162),
            transcript variant 2, mRNA.
ACCESSION   NM_001300834 XM_005270475
VERSION     NM_001300834.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 840)
  AUTHORS   Adams,M.D., Kerlavage,A.R., Fleischmann,R.D., Fuldner,R.A.,
            Bult,C.J., Lee,N.H., Kirkness,E.F., Weinstock,K.G., Gocayne,J.D.,
            White,O. et al.
  TITLE     Initial assessment of human gene diversity and expression patterns
            based upon 83 million nucleotides of cDNA sequence
  JOURNAL   Nature 377 (6547 Suppl), 3-174 (1995)
   PUBMED   7566098
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG545926.1 and CA439311.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001300834.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site, compared to variant 1. The encoded isoform (2) is
            shorter than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DRR138517.604486.1,
                                           SRR5189667.271713.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000369718.4/ ENSP00000358732.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-512               BG545926.1         6-517
            513-840             CA439311.1         16-343              c
FEATURES             Location/Qualifiers
     source          1..840
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p13.2"
     gene            1..840
                     /gene="C1orf162"
                     /note="chromosome 1 open reading frame 162"
                     /db_xref="GeneID:128346"
                     /db_xref="HGNC:HGNC:28344"
     exon            1..47
                     /gene="C1orf162"
                     /inference="alignment:Splign:2.1.0"
     exon            48..95
                     /gene="C1orf162"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..451
                     /gene="C1orf162"
                     /note="isoform 2 is encoded by transcript variant 2;
                     transmembrane protein C1orf162"
                     /codon_start=1
                     /product="transmembrane protein C1orf162 isoform 2"
                     /protein_id="NP_001287763.1"
                     /db_xref="CCDS:CCDS72837.1"
                     /db_xref="GeneID:128346"
                     /db_xref="HGNC:HGNC:28344"
                     /translation="MGGNGSTCKPDTERQGTLSTAAPTTSPAPCLSNHHNKKHLILAF
                     CAGVLLTLLLIAFIFLIIKSYRKYHSKPQAPDPHSDPPAKLSSIPGESLTYASTTFKL
                     SEEKSNHLAENHSADFDPIVYAQIKVTN"
     exon            96..165
                     /gene="C1orf162"
                     /inference="alignment:Splign:2.1.0"
     exon            166..260
                     /gene="C1orf162"
                     /inference="alignment:Splign:2.1.0"
     exon            261..310
                     /gene="C1orf162"
                     /inference="alignment:Splign:2.1.0"
     exon            311..840
                     /gene="C1orf162"
                     /inference="alignment:Splign:2.1.0"
     regulatory      820..825
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1orf162"
                     /note="hexamer: AATAAA"
     polyA_site      840
                     /gene="C1orf162"
                     /note="major polyA site"
ORIGIN      
        1 agtcttagac gactgcgtcg tgctatgacc ggactttttc ttgaaagggg atgacagcat
       61 gggaggcaat ggctccacat gtaaacccga cactgaaaga caaggcactc tctccacagc
      121 agccccaaca actagccctg caccctgtct ctctaaccac cacaacaaaa aacatttaat
      181 ccttgccttt tgtgctgggg ttctactgac actgctgctg atagccttta tcttcctcat
      241 cataaagagc tacagaaaat atcactccaa gccccaggcc ccagatcctc actcagatcc
      301 tccagccaag ctttcatcca tcccagggga atcacttacc tatgccagca caactttcaa
      361 actctcagaa gaaaagagca atcacttggc tgagaaccat tctgcagact ttgaccccat
      421 tgtctatgct caaattaaag taacaaacta actcagcttt tccaatgagg cttgaatcca
      481 tttcctctca tctcagccct atcttcacac atcactttca cttttttaca aattttggac
      541 caccacctgt gtgaaactgc agtcggagtt gtttagatgt gatctggcaa tgctatccag
      601 catctttgga gaccaatggt cagtcttttc ctggccagag gaaagattga tggccctccc
      661 acttgaactg acagcctgtg agccccttgg gggcatagac tgccttcctt ggacccttcc
      721 aaagtgtgtg gtacagagct cagtgcacag agtattcacc cagcatcatg aatcaacttg
      781 ggaggagtca accaaatgaa caatctacca aaaatttcaa ataaagtcaa accccccaca
//
