LOCUS       NM_001007537            1402 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens C1q and TNF related 9B (C1QTNF9B), transcript variant
            1, mRNA.
ACCESSION   NM_001007537 XM_370715
VERSION     NM_001007537.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1402)
  AUTHORS   Dong,F., Jiang,M., Zhang,Z., Li,F. and Lian,Y.
  TITLE     C1q/TNF-related protein-9 suppresses inflammation in synovial cells
            from patients with osteoarthritis
  JOURNAL   Scand J Rheumatol 51 (5), 368-373 (2022)
   PUBMED   34514937
  REMARK    GeneRIF: C1q/TNF-related protein-9 suppresses inflammation in
            synovial cells from patients with osteoarthritis.
REFERENCE   2  (bases 1 to 1402)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 1402)
  AUTHORS   Li,Z., Du,Y., Jia,L., Fan,J., Guo,R., Ma,X., Wang,X., Nie,S. and
            Wei,Y.
  TITLE     Association of C1q/TNF-Related Protein-9 (CTRP9) Level with
            Obstructive Sleep Apnea in Patients with Coronary Artery Disease
  JOURNAL   Mediators Inflamm 2020, 7281391 (2020)
   PUBMED   32831639
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1402)
  AUTHORS   Du,Y., Zhang,S., Yu,H., Wu,Y., Cao,N., Wang,W., Xu,W., Li,Y. and
            Liu,H.
  TITLE     Autoantibodies Against beta1-Adrenoceptor Exaggerated Ventricular
            Remodeling by Inhibiting CTRP9 Expression
  JOURNAL   J Am Heart Assoc 8 (4), e010475 (2019)
   PUBMED   30764693
REFERENCE   5  (bases 1 to 1402)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   6  (bases 1 to 1402)
  AUTHORS   Shi,Y., Qu,J., Zhang,D., Zhao,P., Zhang,Q., Tam,P.O.S., Sun,L.,
            Zuo,X., Zhou,X., Xiao,X., Hu,J., Li,Y., Cai,L., Liu,X., Lu,F.,
            Liao,S., Chen,B., He,F., Gong,B., Lin,H., Ma,S., Cheng,J.,
            Zhang,J., Chen,Y., Zhao,F., Yang,X., Chen,Y., Yang,C., Lam,D.S.C.,
            Li,X., Shi,F., Wu,Z., Lin,Y., Yang,J., Li,S., Ren,Y., Xue,A.,
            Fan,Y., Li,D., Pang,C.P., Zhang,X. and Yang,Z.
  TITLE     Genetic variants at 13q12.12 are associated with high myopia in the
            Han Chinese population
  JOURNAL   Am J Hum Genet 88 (6), 805-813 (2011)
   PUBMED   21640322
REFERENCE   7  (bases 1 to 1402)
  AUTHORS   Peterson,J.M., Wei,Z. and Wong,G.W.
  TITLE     CTRP8 and CTRP9B are novel proteins that hetero-oligomerize with
            C1q/TNF family members
  JOURNAL   Biochem Biophys Res Commun 388 (2), 360-365 (2009)
   PUBMED   19666007
  REMARK    GeneRIF: two novel human C1q/TNF family members, designated as
            CTRP8 and CTRP9B were described.
REFERENCE   8  (bases 1 to 1402)
  AUTHORS   Ghai,R., Waters,P., Roumenina,L.T., Gadjeva,M., Kojouharova,M.S.,
            Reid,K.B., Sim,R.B. and Kishore,U.
  TITLE     C1q and its growing family
  JOURNAL   Immunobiology 212 (4-5), 253-266 (2007)
   PUBMED   17544811
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445985.10.
            
            On Mar 1, 2023 this sequence version replaced NM_001007537.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the protein.
            
            ##Evidence-Data-START##
            CDS exon combination :: EL734395.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA2147596, SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000713589.1/ ENSP00000518885.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-85                AL445985.10        64449-64533         c
            86-190              AL445985.10        64153-64257         c
            191-376             AL445985.10        63852-64037         c
            377-439             AL445985.10        61170-61232         c
            440-1402            AL445985.10        58130-59092         c
FEATURES             Location/Qualifiers
     source          1..1402
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q12.12"
     gene            1..1402
                     /gene="C1QTNF9B"
                     /gene_synonym="CTRP9B"
                     /note="C1q and TNF related 9B"
                     /db_xref="GeneID:387911"
                     /db_xref="HGNC:HGNC:34072"
                     /db_xref="MIM:614148"
     exon            1..85
                     /gene="C1QTNF9B"
                     /gene_synonym="CTRP9B"
                     /inference="alignment:Splign:2.1.0"
     exon            86..190
                     /gene="C1QTNF9B"
                     /gene_synonym="CTRP9B"
                     /inference="alignment:Splign:2.1.0"
     exon            191..376
                     /gene="C1QTNF9B"
                     /gene_synonym="CTRP9B"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..1212
                     /gene="C1QTNF9B"
                     /gene_synonym="CTRP9B"
                     /note="collagen triple helix repeat-containing;
                     C1q/TNF-related protein 9B; complement C1q and tumor
                     necrosis factor-related protein 9B; C1q and tumor necrosis
                     factor related protein 9B"
                     /codon_start=1
                     /product="complement C1q and tumor necrosis factor-related
                     protein 9B precursor"
                     /protein_id="NP_001007538.1"
                     /db_xref="CCDS:CCDS31947.1"
                     /db_xref="GeneID:387911"
                     /db_xref="HGNC:HGNC:34072"
                     /db_xref="MIM:614148"
                     /translation="MRIWWLLLAIEICTGNINSQDTCRQGHPGIPGNPGHNGLPGRDG
                     RDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGSRGSPGKHGP
                     KGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGLPGPMGPIGKP
                     GPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIGETLVLPKSAFTVGLTVLSKFPSSD
                     VPIKFDKILYNEFNHYDTAVGKFTCHIAGVYYFTYHITVFSRNVQVSLVKNGVKILHT
                     RDAYVSSEDQASGSIVLQLKLGDEMWLQVTGGERFNGLFADEDDDTTFTGFLLFSSQ"
     exon            377..439
                     /gene="C1QTNF9B"
                     /gene_synonym="CTRP9B"
                     /inference="alignment:Splign:2.1.0"
     exon            440..1402
                     /gene="C1QTNF9B"
                     /gene_synonym="CTRP9B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caactacgaa catggacatc tgttctagtc cttgctttca attattttgt gtagatgcac
       61 agcagtggaa ttgctggatc agatgcttga agagtggttc caatcacaag tgttaccttc
      121 caaggacaat gtcatcctgg taataaccag cttgctcccc tgccctgagt cttctgccaa
      181 gtctgtccag ttcagtctgt catctgaacc atgaggatct ggtggcttct gcttgccatt
      241 gaaatctgca cagggaacat aaactcacag gacacctgca ggcaagggca ccctggaatc
      301 cctgggaacc ccggtcacaa tggtctgcct ggaagagatg gacgagacgg agcgaagggt
      361 gacaaaggcg atgcaggaga accaggatgt cctggcagcc cggggaagga tgggacgagt
      421 ggagagaagg gagaacgagg agcagatgga aaagttgaag caaaaggcat caaaggtgat
      481 caaggctcaa gaggatcccc aggaaaacat ggccccaagg ggcttgcagg gcccatggga
      541 gagaaaggcc tccgaggaga gactgggcct caggggcaga aggggaataa gggtgacgtg
      601 ggtcccactg gtcctgaggg gccaaggggc aacattgggc ctttgggccc aactggttta
      661 ccgggcccca tgggccctat tggaaagcct ggtcccaagg gagaagctgg acccacgggg
      721 ccccagggtg agccaggagt ccggggaata agaggctgga aaggagatcg aggagagaaa
      781 gggaaaatcg gtgagactct agtcttgcca aaaagtgctt tcactgtggg gctcacggtg
      841 ctgagcaagt ttccttcttc agatgtgccc attaaatttg ataagatcct gtataatgaa
      901 ttcaaccatt atgatacagc agtggggaaa ttcacgtgcc acattgctgg ggtctattac
      961 ttcacctacc acatcactgt tttctccagg aatgttcagg tgtctttggt caaaaacgga
     1021 gtaaaaatac tgcacaccag agatgcttac gtgagctctg aggaccaggc ctctggcagc
     1081 attgtcctgc agctgaagct cggggatgag atgtggctgc aggtgacagg aggagagagg
     1141 ttcaatggct tgtttgctga tgaggacgat gacacaactt tcacagggtt ccttctgttc
     1201 agcagccagt gacagaggag agtttataaa tctgccagac catccatcag aatcagcttg
     1261 ggatgaactt attcagatgg ttttacttta ttaattcctc caattattac aataatcata
     1321 aaaaggtgaa aacggaaaag ttattcccaa aactgattct atgtaactta ctatttttcc
     1381 aggagtaaat atttaaaata gc
//
