LOCUS       NM_182528               1905 bp    mRNA    linear   PRI 01-AUG-2024
DEFINITION  Homo sapiens complement C1q like 2 (C1QL2), mRNA.
ACCESSION   NM_182528
VERSION     NM_182528.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Lemaitre,R.N., King,I.B., Kabagambe,E.K., Wu,J.H., McKnight,B.,
            Manichaikul,A., Guan,W., Sun,Q., Chasman,D.I., Foy,M., Wang,L.,
            Zhu,J., Siscovick,D.S., Tsai,M.Y., Arnett,D.K., Psaty,B.M.,
            Djousse,L., Chen,Y.D., Tang,W., Weng,L.C., Wu,H., Jensen,M.K.,
            Chu,A.Y., Jacobs,D.R. Jr., Rich,S.S., Mozaffarian,D., Steffen,L.,
            Rimm,E.B., Hu,F.B., Ridker,P.M., Fornage,M. and Friedlander,Y.
  TITLE     Genetic loci associated with circulating levels of very long-chain
            saturated fatty acids
  JOURNAL   J Lipid Res 56 (1), 176-184 (2015)
   PUBMED   25378659
REFERENCE   2  (bases 1 to 1905)
  AUTHORS   Davila,S., Froeling,F.E., Tan,A., Bonnard,C., Boland,G.J.,
            Snippe,H., Hibberd,M.L. and Seielstad,M.
  TITLE     New genetic associations detected in a host response study to
            hepatitis B vaccine
  JOURNAL   Genes Immun 11 (3), 232-238 (2010)
   PUBMED   20237496
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 1905)
  AUTHORS   Wong,G.W., Krawczyk,S.A., Kitidis-Mitrokostas,C., Revett,T.,
            Gimeno,R. and Lodish,H.F.
  TITLE     Molecular, biochemical and functional characterizations of C1q/TNF
            family members: adipose-tissue-selective expression patterns,
            regulation by PPAR-gamma agonist, cysteine-mediated
            oligomerizations, combinatorial associations and metabolic
            functions
  JOURNAL   Biochem J 416 (2), 161-177 (2008)
   PUBMED   18783346
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC016673.5.
            
            On Nov 23, 2018 this sequence version replaced NM_182528.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF525315.1, BC043189.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA2145743
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000272520.4/ ENSP00000272520.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1166              AC016673.5         82107-83272         c
            1167-1905           AC016673.5         80764-81502         c
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q14.2"
     gene            1..1905
                     /gene="C1QL2"
                     /gene_synonym="C1QTNF10; CTRP10"
                     /note="complement C1q like 2"
                     /db_xref="GeneID:165257"
                     /db_xref="HGNC:HGNC:24181"
                     /db_xref="MIM:614330"
     exon            1..1166
                     /gene="C1QL2"
                     /gene_synonym="C1QTNF10; CTRP10"
                     /inference="alignment:Splign:2.1.0"
     CDS             483..1346
                     /gene="C1QL2"
                     /gene_synonym="C1QTNF10; CTRP10"
                     /note="complement component 1, q subcomponent-like 2;
                     C1q-domain containing protein; complement C1q-like protein
                     2; C1q/TNF-related protein 10; C1q and tumor necrosis
                     factor-related protein 10"
                     /codon_start=1
                     /product="complement C1q-like protein 2 precursor"
                     /protein_id="NP_872334.2"
                     /db_xref="CCDS:CCDS42737.1"
                     /db_xref="GeneID:165257"
                     /db_xref="HGNC:HGNC:24181"
                     /db_xref="MIM:614330"
                     /translation="MALGLLIAVPLLLQAAPRGAAHYEMMGTCRMICDPYTAAPGGEP
                     PGAKAQPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPR
                     GPPGEKGDSGRPGLPGLQLTAGTASGVGVVGGGAGVGGDSEGEVTSALSATFSGPKIA
                     FYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTS
                     MWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKY
                     STFSGFLLYPD"
     exon            1167..1905
                     /gene="C1QL2"
                     /gene_synonym="C1QTNF10; CTRP10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1882..1887
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1QL2"
                     /gene_synonym="C1QTNF10; CTRP10"
                     /note="hexamer: ATTAAA"
     polyA_site      1905
                     /gene="C1QL2"
                     /gene_synonym="C1QTNF10; CTRP10"
                     /note="major polyA site"
ORIGIN      
        1 agagcgcgcc gcggagccgg ggcgccctca ctgcgctagg agccccacta aacccagcgg
       61 agcggagcct ggcgggaggc agcgccgcgg agccagcgcc ggacgccgca agcagactcc
      121 ccggccagcg caagcactcc ctggccggcg ccggaccctc ggggcgccgg attcgtcttg
      181 tgtgccccac gtcatgcgcg cgggcgtccg cggctctccc gaccagcccc agcgcggtgg
      241 gcccaggctc agaggtcccg gcgcctctcg ctgaagtagt tgggtagccg gggctggggg
      301 tcgccacgtc gggggcgcgg ccaggacccg cggagccggt ccccgagcgc ggggagcggg
      361 gccgcccgcg ccgccccacc attacctccc cgggcggcaa ggaggagctg gtggcggtcg
      421 cctcccggct gtggcagcgg cggcggcgtg cctgcctggc ggccgtcggc gtactcttgg
      481 ccatggcgct cgggctgctc atcgccgtgc cgctgctgct gcaggcggcg ccccgaggcg
      541 ccgcgcacta tgagatgatg ggcacctgcc gcatgatctg cgacccttac actgccgcgc
      601 ccggcgggga gcccccgggt gcaaaggcgc agccacccgg acccagcacc gccgccctgg
      661 aagtcatgca ggacctcagc gccaaccctc ctcctccttt catccaggga cccaagggcg
      721 acccggggcg accgggcaag ccagggccgc gggggccccc tggagagccg ggcccgcctg
      781 gacccagggg ccctccggga gagaagggcg actcggggcg gcccgggctg ccagggctgc
      841 aactgacggc gggcacggcc agcggcgtcg gggtggtggg cggcggggcc ggggtaggtg
      901 gcgattccga gggtgaagtg accagtgcgc tgagcgccac cttcagcggc cccaagatcg
      961 ccttctatgt gggtctcaag agcccccacg aaggctatga ggtgctgaag ttcgatgacg
     1021 tggtcaccaa cctcggcaat cactatgacc ccaccacggg caagttcagc tgccaggtac
     1081 gcggcatcta cttcttcacc taccacatcc tcatgcgcgg cggcgacggc accagcatgt
     1141 gggcggacct ctgcaagaac gggcaggtcc gggccagcgc cattgcacag gacgccgacc
     1201 agaactacga ctacgccagt aacagcgtgg tgctgcactt ggattcaggg gacgaagtgt
     1261 atgtgaagct ggatggcggg aaggctcacg gaggcaataa taacaagtac agcacgttct
     1321 cgggctttct tctgtacccg gattaggggc gcggggggtg cgaggcgggg tggctgcagg
     1381 ccgcccggtc tccgcccggg cgcggctcct tggcaaaggc cactctcgat tcataacact
     1441 tcctgacatc tcctttggaa aagacaaatc cctgcgtcct ccctgccccg ctcctggcct
     1501 cagtgcgtct gcgacccacc acgctcaggg ctgtgctcct ggtctccatc cccatcccgg
     1561 caagggagga agggacgccc gagcccttga ggcggcggca cagactttgc aaacctgatt
     1621 agactggaca ggcagggccg ggagcctgcc ctcctcagac agcctcctcc cagtgcctag
     1681 aagcggaggg ctccgggccc tggccaggga ggtaggccag agggagcgcg ggcttcctgg
     1741 ggcgtccttc tttgtgaccc gaaatacttg tgcagatttc cctgtccatc agccaaaacc
     1801 ccacccacag cagaattcca gcaaacagaa aattcacctc tccacaccgc attccctcct
     1861 gactcagact caccgcgatg cattaaatta tgtttttaga ctatg
//
