LOCUS       NM_018111                742 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens chromosome 19 open reading frame 73 (C19orf73), mRNA.
ACCESSION   NM_018111
VERSION     NM_018111.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Rolland,T., Tasan,M., Charloteaux,B., Pevzner,S.J., Zhong,Q.,
            Sahni,N., Yi,S., Lemmens,I., Fontanillo,C., Mosca,R., Kamburov,A.,
            Ghiassian,S.D., Yang,X., Ghamsari,L., Balcha,D., Begg,B.E.,
            Braun,P., Brehme,M., Broly,M.P., Carvunis,A.R., Convery-Zupan,D.,
            Corominas,R., Coulombe-Huntington,J., Dann,E., Dreze,M., Dricot,A.,
            Fan,C., Franzosa,E., Gebreab,F., Gutierrez,B.J., Hardy,M.F.,
            Jin,M., Kang,S., Kiros,R., Lin,G.N., Luck,K., MacWilliams,A.,
            Menche,J., Murray,R.R., Palagi,A., Poulin,M.M., Rambout,X.,
            Rasla,J., Reichert,P., Romero,V., Ruyssinck,E., Sahalie,J.M.,
            Scholz,A., Shah,A.A., Sharma,A., Shen,Y., Spirohn,K., Tam,S.,
            Tejeda,A.O., Wanamaker,S.A., Twizere,J.C., Vega,K., Walsh,J.,
            Cusick,M.E., Xia,Y., Barabasi,A.L., Iakoucheva,L.M., Aloy,P., De
            Las Rivas,J., Tavernier,J., Calderwood,M.A., Hill,D.E., Hao,T.,
            Roth,F.P. and Vidal,M.
  TITLE     A proteome-scale map of the human interactome network
  JOURNAL   Cell 159 (5), 1212-1226 (2014)
   PUBMED   25416956
REFERENCE   2  (bases 1 to 742)
  AUTHORS   Lamesch,P., Li,N., Milstein,S., Fan,C., Hao,T., Szabo,G., Hu,Z.,
            Venkatesan,K., Bethel,G., Martin,P., Rogers,J., Lawlor,S.,
            McLaren,S., Dricot,A., Borick,H., Cusick,M.E., Vandenhaute,J.,
            Dunham,I., Hill,D.E. and Vidal,M.
  TITLE     hORFeome v3.1: a resource of human open reading frames representing
            over 10,000 human genes
  JOURNAL   Genomics 89 (3), 307-315 (2007)
   PUBMED   17207965
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008687.5, BC069750.1 and BC051004.1.
            
            On Nov 23, 2018 this sequence version replaced NM_018111.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK001352.1, BC051004.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000408991.4/ ENSP00000386230.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC008687.5         130449-130451       c
            4-495               BC069750.1         1-492
            496-742             BC051004.1         498-744
FEATURES             Location/Qualifiers
     source          1..742
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.33"
     gene            1..742
                     /gene="C19orf73"
                     /note="chromosome 19 open reading frame 73"
                     /db_xref="GeneID:55150"
                     /db_xref="HGNC:HGNC:25534"
     exon            1..742
                     /gene="C19orf73"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..511
                     /gene="C19orf73"
                     /codon_start=1
                     /product="putative uncharacterized protein C19orf73"
                     /protein_id="NP_060581.2"
                     /db_xref="CCDS:CCDS42589.1"
                     /db_xref="GeneID:55150"
                     /db_xref="HGNC:HGNC:25534"
                     /translation="MRLKVGFQGGGCFRKDALCLEGGVSARWARAPHSAPLRPPRELH
                     AAPPPATPTQTVVRPAGFPRRTRLMVRSAPPTQRPPTGSGCVSGLWRKGLGLRPQTLL
                     RVGSVVLSSAPALRPRLGPCLRPPPSD"
     regulatory      703..708
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C19orf73"
                     /note="hexamer: AATAAA"
     regulatory      720..725
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C19orf73"
                     /note="hexamer: AATAAA"
     polyA_site      725
                     /gene="C19orf73"
                     /note="major polyA site"
     polyA_site      742
                     /gene="C19orf73"
                     /note="major polyA site"
ORIGIN      
        1 gatgatgtca cctggagcga gtagcgcgcg gcgtggaacg cgagtcgcga ccccggctcc
       61 cggcagtggc gcgcactagc cctcgcgccg cacgggacac gagggctggg cgggcagcgg
      121 gatgaggcta aaggttggat ttcaaggcgg gggctgcttc cggaaagacg cgctgtgttt
      181 ggaaggtgga gtgagcgccc ggtgggcgag ggcacctcat tctgcacccc tgcgcccgcc
      241 tcgggaactg cacgcggcac ccccacccgc gactcccacg cagacagtag tgcggcctgc
      301 agggttcccc cggcggacga ggctaatggt tcgctccgcc ccgcccacac agaggccgcc
      361 cactggctcc ggctgcgttt caggactctg gaggaaggga cttggccttc gccctcagac
      421 gctcttaagg gtaggcagcg ttgtcctcag ttctgcccca gcactcagac ccagactggg
      481 tccctgcctc cgccctccgc cctcggacta gtctcttgga agccggcctg tctccgcctt
      541 cagacctagg gagaggtctt aacctctgtt ctcagactct ggaaaaggct tctcaacggc
      601 ttggcctgac ctcagctcct cgcattccct ccacatctca agacaccaac ccagggatgc
      661 aggacagaca cacagacact cagtgagggt caaatatctt taaataaagt gccaggaaca
      721 ataaatactg tacaggaaga ga
//
