LOCUS       NM_152474                915 bp    mRNA    linear   PRI 12-SEP-2020
DEFINITION  Homo sapiens chromosome 19 open reading frame 18 (C19orf18), mRNA.
ACCESSION   NM_152474
VERSION     NM_152474.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall
            R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Cote AG,
            Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF,
            Kishore N, Knapp JJ, Kovacs IA, Lemmens I, Mee MW, Mellor JC,
            Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A,
            Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG,
            Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S,
            Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A,
            Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van
            Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S,
            Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli
            D, Sheynkman GM, Simonovsky E, Tasan M, Tejeda A, Tropepe V,
            Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X,
            Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S,
            Hao T, Rak J, Tavernier J, Hill DE, Vidal M, Roth FP and Calderwood
            MA.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC033933.2.
            
            On May 17, 2019 this sequence version replaced NM_152474.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC033933.2, BI560027.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148093, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000314391.3/ ENSP00000321519.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-915               BC033933.2         4-918
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..915
                     /gene="C19orf18"
                     /note="chromosome 19 open reading frame 18"
                     /db_xref="GeneID:147685"
                     /db_xref="HGNC:HGNC:28642"
     exon            1..223
                     /gene="C19orf18"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..750
                     /gene="C19orf18"
                     /note="uncharacterized protein C19orf18"
                     /codon_start=1
                     /product="uncharacterized protein C19orf18 precursor"
                     /protein_id="NP_689687.1"
                     /db_xref="CCDS:CCDS12967.1"
                     /db_xref="GeneID:147685"
                     /db_xref="HGNC:HGNC:28642"
                     /translation="MDKVQSGFLILFLFLMECQLHLCLPYADGLHPTGNITGLPGSKR
                     SQPPRNITKEPKVFFHKTQLPGIQGAASRSTAASPTNPMKFLRNKAIIRHRPALVKVI
                     LISSVAFSIALICGMAISYMIYRLAQAEERQQLESLYKNLRIPLLGDEEEGSEDEGES
                     THLLPENENELEKFIHSVIISKRSKNIKKKLKEEQNSVTENKTKNASHNGKMEDL"
     exon            224..328
                     /gene="C19orf18"
                     /inference="alignment:Splign:2.1.0"
     exon            329..370
                     /gene="C19orf18"
                     /inference="alignment:Splign:2.1.0"
     exon            371..473
                     /gene="C19orf18"
                     /inference="alignment:Splign:2.1.0"
     exon            474..634
                     /gene="C19orf18"
                     /inference="alignment:Splign:2.1.0"
     exon            635..915
                     /gene="C19orf18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      893..898
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C19orf18"
                     /note="hexamer: AATAAA"
     polyA_site      915
                     /gene="C19orf18"
                     /note="major polyA site"
ORIGIN      
        1 agtagaactt cttgattcct cagataaata gaggacagat gctggactgt agctaagtat
       61 ttcctttcat ctacgggata aaatactgat aatttgagag tgatggacaa ggttcagagt
      121 ggtttcctca ttttgttttt gtttttaatg gaatgccaac ttcatttatg cttgccgtat
      181 gcagatggac tccatcccac tggaaacata acaggcttac caggcagtaa acggtcacaa
      241 ccacccagaa acatcaccaa agagcccaaa gtgttctttc ataaaaccca gttgcctggg
      301 attcaagggg ctgcctcgag atccacggct gcatccccta cgaaccccat gaaattcctg
      361 aggaataaag caataattcg gcatagacct gctcttgtta aagtaatttt aatttcgagc
      421 gtagccttca gcattgccct gatatgtggg atggcaatct cctatatgat atatcgactg
      481 gcacaggctg aggaaagaca acagctcgag tcactttata agaacctcag gataccgtta
      541 ttaggagatg aagaagaggg ctcagaggac gagggtgagt ccacgcacct acttccagag
      601 aacgaaaatg agctggaaaa gttcatccac tcagttatta tatcaaaaag aagcaaaaat
      661 attaagaaga aactgaagga agagcaaaac tcagtaacag aaaacaaaac aaagaatgcg
      721 tcacataatg gaaaaatgga agacttgtga acgcagacga cagaggtgcc ggctgaggca
      781 gaggagaaac tatgggggtg ctgggagact gagcctgtgg gcgtggcttg ctcccagaga
      841 accttatgga agaggacatc aaagaaagaa atgccagacc tgtatcccag aaaataaagc
      901 cacatgatat agcaa
//
