LOCUS       NM_001174123            5103 bp    mRNA    linear   PRI 02-JUN-2022
DEFINITION  Homo sapiens chromosome 18 open reading frame 63 (C18orf63), mRNA.
ACCESSION   NM_001174123 XR_042010 XR_042011 XR_042012
VERSION     NM_001174123.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC090398.12 and AC008021.10.
            
            On May 17, 2019 this sequence version replaced NM_001174123.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR749350.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000579455.2/ ENSP00000464330.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-271               AC090398.12        122104-122374
            272-437             AC090398.12        124099-124264
            438-516             AC090398.12        126778-126856
            517-573             AC090398.12        128963-129019
            574-685             AC008021.10        96573-96684
            686-727             AC008021.10        97621-97662
            728-804             AC008021.10        99492-99568
            805-914             AC008021.10        107341-107450
            915-1011            AC008021.10        110658-110754
            1012-1097           AC008021.10        110867-110952
            1098-1281           AC008021.10        112145-112328
            1282-2304           AC008021.10        121872-122894
            2305-2394           AC008021.10        123083-123172
            2395-5103           AC008021.10        125107-127815
FEATURES             Location/Qualifiers
     source          1..5103
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18q22.3"
     gene            1..5103
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /note="chromosome 18 open reading frame 63"
                     /db_xref="GeneID:644041"
                     /db_xref="HGNC:HGNC:40037"
     exon            1..271
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            272..437
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     CDS             304..2361
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /codon_start=1
                     /product="uncharacterized protein C18orf63"
                     /protein_id="NP_001167594.1"
                     /db_xref="CCDS:CCDS54189.1"
                     /db_xref="GeneID:644041"
                     /db_xref="HGNC:HGNC:40037"
                     /translation="MNDSRQQSLFFITLPDLNKLCAVRIILSNKVADTEIRTIQMKMC
                     RQLLFLHQDILTSPVSGILNQIWVVMAIPFYKARKLNAYVEKYGAKMEAPQRVIPVIL
                     QNCLSYSFMARLAPAWNRTGHLLIQGRDFLSQMGKQSAVVLNINVTETQVCLSIEACT
                     IRLPAPELKEFEISQSIIKDFHANKHAVIERHSILSNWCYVLPSMKMGQIINIFHAIP
                     AACPFHSYGDFQRHWDALYGYKLPGDCGKIKIYCNIYFKMLGERTFTYPLSCIRSQPM
                     QFFPRVDSEVVLKSFLSDLKSKLPHICGFPIKMTSKPCYYTQELTKPNIQEHKVKPPN
                     LTTKKMLRASLTQATSRKPACAQSLLPCSVAVDHKVELSVSQPTSGIFSALHLQPESV
                     QGRKKSLSIRAPQVHSEVLMPNRGNTQVQHTNLSSQSNITPKFVPVFKNRLLQMNKNT
                     SVLGSPKRKQHDVTQSKLFSLKTSMIQHDKLNLGPAIKNRYSSNIQMQAANNLNQENS
                     RPLQEKNTESSENMTKFPSSRGKSTVSLNKNKQLSNSAVFVVSNNNLGVVKSAVDFQM
                     KGKENLTGKGITQILGKSHGSLKLKRQPHIFESDGETEDPRLLQQQSENQAKEVGTSD
                     HRLIVSKIAHRSKRKLCPESSKTSKKHHSDTVHYGQSSSSKKQILDSDKSKLKKSLII
                     HNA"
     exon            438..516
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            517..573
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            574..685
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            686..727
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            728..804
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            805..914
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1011
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1097
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1281
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..2304
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            2305..2394
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     exon            2395..5103
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5083..5088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /note="hexamer: AATAAA"
     polyA_site      5103
                     /gene="C18orf63"
                     /gene_synonym="DKFZP781G0119"
                     /note="major polyA site"
ORIGIN      
        1 actccgatga aggcagggca cgcggggcga gccgggagcg tctcctgagg gcagcgagga
       61 gggagctgag gcacgcgggc tctcaatcga cgccccacag agaccaagag gcctggcctt
      121 ggggggcagc tgcttgaagg aggcagagcg gaagcgaggg agactgctgg aggccctgcc
      181 gcccacccgc cctttcctcc ccctgaggag acgcctgacg catctgcagt gcaggaggcc
      241 gtgggcgtta gaagtgttgc ttttccagtt tgcctgattg ctgagacact cagtcaggaa
      301 agtatgaatg attctaggca gcagtctctg ttcttcatca cacttccaga tttaaacaaa
      361 ctctgtgctg tcagaataat actgagtaat aaggtggcag atactgagat taggactata
      421 caaatgaaga tgtgcaggca attgctgttt ttgcatcaag atattcttac atcacctgtg
      481 tctggaatat taaaccaaat ctgggtggtg atggcgatac cattttataa agcaagaaaa
      541 cttaatgcct atgttgaaaa atatggagct aagatggagg ctccacaaag agtaattcct
      601 gtaattcttc agaactgcct gtcatattca ttcatggcta gacttgctcc agcctggaat
      661 agaactggtc atctcttgat acaaggaaga gattttcttt ctcagatggg aaaacaaagt
      721 gctgttgtat taaacatcaa tgtaacagaa actcaagttt gtctaagtat agaagcttgc
      781 acaatcagac tgccagcacc tgagctaaaa gagtttgaga tttcccagag tattataaag
      841 gattttcatg ctaacaagca tgctgtcatt gagagacatt ccattttaag caactggtgc
      901 tacgttttgc caagtatgaa aatgggacaa attataaata tttttcatgc catccccgct
      961 gcctgtcctt ttcactcata tggagatttc cagagacact gggatgccct gtatggctat
     1021 aaacttccag gtgattgtgg aaaaattaaa atatactgca acatctattt caaaatgctc
     1081 ggagaaagga ccttcacata tcctctcagt tgcatcagaa gtcagcccat gcagttcttt
     1141 ccaagggtag attcggaagt tgtgttgaaa agttttcttt cagatttaaa atctaaactg
     1201 ccccatatat gtggatttcc cataaagatg acaagtaaac catgctacta cacacaagaa
     1261 ctaactaaac ctaatataca ggaacacaaa gtcaagccac ccaatttgac cactaaaaaa
     1321 atgcttaggg catctctgac tcaagccact tccagaaagc ctgcctgtgc tcaaagtctt
     1381 ctaccatgtt cagtagcagt ggaccacaag gtggagcttt cagtcagcca gccaacatca
     1441 ggcattttct cagctttgca tctccagcca gagtctgttc agggtagaaa gaaatccctg
     1501 tctatcaggg ctccacaagt acattcagaa gtattaatgc ccaacagagg aaatactcaa
     1561 gttcagcaca caaatcttag ctcccaaagc aacatcaccc ctaagtttgt accagttttc
     1621 aaaaatagat tgttacaaat gaacaaaaat acctcagtac ttggcagccc aaaaagaaaa
     1681 cagcatgatg tgacacaatc taaattgttt tcactcaaaa ctagtatgat ccagcatgac
     1741 aaactgaatt taggtccagc tataaaaaac cgttatagta gtaacattca gatgcaggct
     1801 gctaacaatt taaatcagga gaattccaga cctctgcaag aaaaaaatac agagtcttct
     1861 gaaaatatga caaaatttcc ctcttctcgt ggaaaatcga ctgtgagttt aaacaaaaat
     1921 aagcaactat ctaatagtgc agtatttgtg gtgtcaaata acaatttagg ggtggtaaaa
     1981 agtgctgttg acttccaaat gaaaggaaaa gaaaatttaa caggcaaagg tataacacaa
     2041 attttaggga aaagccatgg gtcactaaaa ctgaaaagac agccacacat ttttgaatca
     2101 gatggagaaa ccgaagatcc acgactgcta cagcagcaat cagaaaatca agctaaagaa
     2161 gttggtacaa gtgaccacag gttgatagta agcaaaatag cccacaggtc taaaagaaaa
     2221 ttatgtccag agtcttccaa aacttcaaag aagcatcatt ccgatactgt gcactatggc
     2281 caatccagtt cttctaagaa gcagatactt gactcggata aatcaaaact taagaaatct
     2341 ctcatcattc ataatgctta gaacatggac ctgaaagaag gaaatgtcta ccagagatga
     2401 gcattctgaa tataggatga acactcttcc agatgcctct cacactcctg tgaccatgaa
     2461 atcagctcta cttactgctg tggaacctcc tttttcactt gacagtttct ttttattgtt
     2521 tgcatagcat cttgttgtat gtgggtttct gtatttaact agtcccctat tgatagacac
     2581 ttcagttctt cccaactttt cactattaca acatcatgta gtctgcagat ctttgcaaaa
     2641 tatccaatga tcttatacag tagttttgat agttgaaaat atctttattt tgcccttatt
     2701 gaaattatca aaccacataa agcacagata agagtatgaa gaacctctaa gtacctatca
     2761 cccagatcta ccagttatta atattttgcc actgtttcat ctgttcctca cagacatgct
     2821 tttttttgct ataatctttt aaagcaaatt caagacatca tataatttta cccataaaca
     2881 ccaaagtgta tatatttcta acataagata tagtatattt tttaagaaaa aaagaatgtg
     2941 tatatatata ttacattttg gggatctcta ctatatctct gcaggctcac taaatttcac
     3001 ttttgctttt atatgcaaat taacaggaag ccctgaataa atgtaaaagc tatttctcaa
     3061 caaaactgga gcctttattg gggtggagat ttctgtttcc accagtactc attagcatct
     3121 tctgtgtgcc aggcagtggg gacaacactg tgtccatggc agaaatggat gagacagccg
     3181 tggcctgagc ccctgagtgc tggtggtcta gtctcaagca aattcattct gggttcctgg
     3241 cacagactta gggatatgta tgtattgaag catatgtcca gaatgacctt ctagtccata
     3301 ttacaaataa attatctaac atttgaaaaa aagagaaaca gaagtggagc ttctcagaca
     3361 atgaatatta ttctggcttt caaacatttt atatgtttga tatacgaaat attatataat
     3421 tgttgtaata tatttaaaag aaaccaaaat cttcattggc tattccactg aaacaataat
     3481 tacataaaaa tagccactag agatccaagt ataagttgaa ctctgatttt gtaaatgtga
     3541 tttattgtct ccaccacttt actaaaccat tgcaattaaa agcaaaagta aacaaactct
     3601 ccttcaaacg ttaaatgtta actcctgctc ctgaaattgt gtttagttaa ttaatttgct
     3661 atataccttt attgtaagca tttctgtttt ccagaattat ctctatttcc caattatttt
     3721 accattttca taaggataag cattttgtct gaagcccatt ttgagtgtgc ttttctcatt
     3781 ccaaagtttg tattatagat atctagtaga ctgttataaa gagtggtatg tcattttgtt
     3841 tatgaggcta tggtgaaaat aacattagta aatatgcatt tttgatgagc acagtcatcc
     3901 acagcatgta atcattccta aaaccagcct tccccactgt tccatacatt cccaggccac
     3961 cttcctgcta ctgcccagtc actatgcctc aggtaatgga cacttacttt attattacac
     4021 tgagcaaaat aatgaaaacc atacatccac tgctgaagtg gtattaacat cttccagttc
     4081 tttatataaa taatcttgat agcccctcct atactccatt agtgtctaaa atttagaata
     4141 tatagtatag tacttgagtt tagatcaatg ttaacctaca tggcaaaacc tgccatgttt
     4201 agtgtatttt tttgtataaa gtaggtttga tttttatctt acaatattta tcctaatgaa
     4261 agttataaaa atatatgcat atatttatat gtgagattta atatagatag gtatatagat
     4321 tgttgatttc atatttcatg ttccaagaag aggttctaga tcaaatttct gtgttcagaa
     4381 tcaccagaga aatcaattaa gattttggtt cattttaaac attgcaattt ttgaaagcca
     4441 agataattcc aaatctaatt agggaaagct acattttact tctttgtgta agttattggt
     4501 gatttatatg cagtatggac catcctcccc ccagaaatta ttcttatatt ccaattgtgc
     4561 attagtttta gaaccatttt aattttaaaa ccataagaaa ataattttat gtttgcctat
     4621 gtccaggagc tgaagaaatc agcgattact ttaaaaaata tatggcaatg tcaaaataaa
     4681 tgccaagaat catatttcta ggaatgcaaa agtgcttctc atatactcat atattaggtt
     4741 tcacagtatt ggttgcttac tatatttgtt tttattttta ttatatatca taattacaca
     4801 tttttatttg catttgttgc ttattgtagt aaaaaggtaa aaaaaaaatg aacttgttaa
     4861 tgattagctt ttatttgact aaccagttga ccaattttgc tctgttttca aattgcatat
     4921 gatggggtat tatgctgaaa ctgctaatat attgggtatt tattgatact taggaatagt
     4981 cagtatttat aaatatttaa gaatgtcatg gtccttatgt tttgatgttt aaaatgttca
     5041 ctttgttgta cgttacatag tgtcttattc aaaattgaaa ataataaagg tatttctaat
     5101 aga
//
