LOCUS       NM_001358661            3733 bp    mRNA    linear   PRI 30-OCT-2022
DEFINITION  Homo sapiens chromosome 17 open reading frame 113 (C17orf113),
            mRNA.
ACCESSION   NM_001358661
VERSION     NM_001358661.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC105024.8,
            HY042004.1 and DN831705.1.
            
            On May 17, 2019 this sequence version replaced NM_001358661.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7346977.1774442.1,
                                           SRR3476690.869758.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA2144120
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000587304.3/ ENSP00000490245.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC105024.8         72369-72370         c
            3-231               HY042004.1         1-229
            232-541             AC105024.8         64837-65146         c
            542-1217            DN831705.1         51-726
            1218-3733           AC105024.8         60001-62516         c
FEATURES             Location/Qualifiers
     source          1..3733
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.2"
     gene            1..3733
                     /gene="C17orf113"
                     /note="chromosome 17 open reading frame 113"
                     /db_xref="GeneID:110806298"
                     /db_xref="HGNC:HGNC:53437"
     exon            1..45
                     /gene="C17orf113"
                     /inference="alignment:Splign:2.1.0"
     exon            46..775
                     /gene="C17orf113"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..2260
                     /gene="C17orf113"
                     /note="transmembrane protein C17orf113"
                     /codon_start=1
                     /product="uncharacterized protein C17orf113"
                     /protein_id="NP_001345590.1"
                     /db_xref="CCDS:CCDS86598.1"
                     /db_xref="GeneID:110806298"
                     /db_xref="HGNC:HGNC:53437"
                     /translation="MVPPGKKPAGEASNSNKKCKRYFNEHWKEEFTWLDFDYERKLMF
                     CLECRQALVRNKHGKAENAFTVGTDNFQRHALLRHVTSGAHRQALAVNQGQPPFEGQA
                     EGGGACPGLATTPASRGVKVELDPAKVAVLTTVYCMAKEDVPNDRCSALLELQRFNLC
                     QALLGTEHGDYYSPRRVRDMQVAIASVLHTEACQRLKASPYVGLVLDETRDWPESHSL
                     ALFATSVSPCDGQPATTFLGSVELQEGEATAGQLLDILQAFGVSAPKLAWLSSSLPSE
                     RLGSVGPQLRATCPLLAELHCLPGRTDPEPPAYLGQYESILDALFRLHGGPSSHLVPE
                     LRAALDLAAIDLAGPRPVPWASLLPVVEAVAEAWPGLVPTLEAAALASPVAGSLALAL
                     RQFTFVAFTHLLLDALPSVQKLSLVLQAEEPDLALLQPLVMAAAASLQAQRGSGGARL
                     QGFLQELASMDPDASSGRCTYRGVELLGYSEAAVRGLEWLRGSFLDSMRKGLQDSYPG
                     PSLDAVAAFAAIFDPRRYPQAPEELGTHGEGALRVLLRGFAPAVVRQRALGDFALFKR
                     VVFGLGRLGPRALCTQLACAHSELHELFPDFAALAALALALPAGAGLLDKVGRSRELR
                     WWGQSGAGEGRGGHMVKIAVDGPPLHEFDFGLAVEFLESGWGEGFLGSQLT"
     exon            776..3733
                     /gene="C17orf113"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3286
                     /gene="C17orf113"
     regulatory      3709..3714
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C17orf113"
                     /note="hexamer: AATAAA"
     polyA_site      3733
                     /gene="C17orf113"
                     /note="major polyA site"
ORIGIN      
        1 gcggccagag cgtccaccgc ccaagatggt ggctcctgtg tctcctctcc caccggcaga
       61 gcaggaataa actctccagg cttagatgga tgggccctgt tagcctggcg ggctgccccc
      121 agcctgcctc cccatcaact ctccttgtca agggaggtgc ctgtgtgtgg gggaggcagg
      181 ggggcaagag cattcaggtg ggggttgggg gttccttgct gagagagcaa gaatggtgcc
      241 cccagggaag aaaccagcgg gagaggcctc caactccaac aagaagtgta agcgttactt
      301 caacgagcac tggaaagagg agtttacctg gctggacttt gactatgagc ggaagctgat
      361 gttctgcctc gagtgccgcc aggccctggt acggaacaag catggcaaag ccgaaaacgc
      421 cttcactgtg ggcacagaca acttccagcg ccacgccctg ctgcgccacg tgacctcagg
      481 agcccaccgc caggctctgg ctgtcaacca gggccagccc ccttttgagg gccaggctga
      541 aggtggaggg gcctgcccag gcctggctac gacccctgcc tccaggggcg tcaaggtgga
      601 gttagacccg gccaaagtgg ctgtgctgac tactgtgtac tgcatggcaa aggaggatgt
      661 gcccaatgac cgctgctctg ccctgctcga gctgcagagg ttcaacctgt gccaggcact
      721 gctgggcaca gagcatggcg attactacag tcccaggagg gtgagggaca tgcaggtggc
      781 cattgccagt gtcttgcaca cagaggcctg ccagcgcctg aaggcatccc catatgtggg
      841 gctggtgttg gacgagacca gagactggcc ggagtcacac agcctggccc tgtttgccac
      901 ttcagtgtcc ccctgtgatg gccagcccgc caccaccttc ctgggcagtg tggagctaca
      961 ggagggcgag gccactgctg gccagctctt ggacatcctg caggctttcg gcgtatctgc
     1021 acccaagctg gcctggctca gctcaagcct ccccagtgag cgcctgggga gtgtgggccc
     1081 acagctccgg gccacttgcc cactgctggc agagctgcat tgtctccctg gccggacaga
     1141 tcctgagccc ccggcctact tgggtcaata tgagagcata ttggatgccc tattccgcct
     1201 ccatggtggc cctagttccc acttggtccc tgagctccgg gcagcactgg accttgcagc
     1261 tattgacttg gcagggcctc ggccagtgcc ctgggcctcc ctgctgcctg tagtggaagc
     1321 agtggccgag gcctggcctg gcctggtgcc caccctggag gctgcagccc ttgcctcacc
     1381 tgtggcgggg tcactggccc tggccctgcg ccagttcacc ttcgtggcct tcacccacct
     1441 gctgctggat gccctgccct ctgtgcagaa gctctccctt gtcctgcagg cagaagagcc
     1501 ggacttggcc ttgctgcagc ctctggtgat ggcggctgcg gcctccctcc aagctcagcg
     1561 cggctcaggt ggggcccgcc tccagggctt cctgcaggaa ctggcatcca tggaccctga
     1621 cgccagcagc ggacgctgca cctaccgcgg cgtggagctg ctcggttact ccgaggctgc
     1681 ggtccggggc ttggagtggc tccggggatc cttcctggac tccatgcgga agggcctaca
     1741 ggactcctac cccgggcctt cgctggacgc cgtggccgcc ttcgcagcga tcttcgaccc
     1801 ccgacgctac ccgcaggcgc cggaggagct gggcacgcat ggcgaggggg cgctgcgggt
     1861 gctgctgcgc ggctttgctc ctgccgtggt gcgccagcgg gcgctgggcg acttcgcgct
     1921 gtttaagcgc gtagtattcg gccttgggcg gctcggcccg cgggccctgt gcacccagct
     1981 ggcgtgcgcg cactcggagc tgcacgagct cttccccgac ttcgccgccc tagccgcctt
     2041 ggctttggcg ctgcccgcgg gcgctggcct gctggacaag gtcggccgca gccgggagct
     2101 gcggtggtgg gggcagagtg gggccgggga aggccggggg ggccacatgg tgaagatcgc
     2161 agtggatggg cccccgctgc acgagtttga cttcgggttg gctgtggagt tcttagagag
     2221 tgggtgggga gagggcttcc tggggtcgca gctcacctga gggtggcctc cttccctcgg
     2281 cccatccagc ctggggccct gggcactgta agggccaacc tagacttgac catgctgcac
     2341 ccaagatgat ctgctgactg cagcctccca ggggcctgag gccatccacc cgcccttctg
     2401 gagcttccca ccaacccccc ccaccctgtg ggctgtggag gaagggactg gctcaagagg
     2461 ggcctgggcg ggtgggcaga gatgctagga tctggggtac cctaaatcat tcctggcctt
     2521 tacacagtta gatgaggagt agctcaccct tttcccttct ggactcgggg caagtttggg
     2581 tccccccaaa gatgggagtt tttggcttgg ggaaggaaga ctaggtcttg gaaattgagt
     2641 ggctgaggga acggacactg gtccttggtc cttggctgtt tctttctttt tcttttcttt
     2701 ttttttcttt ttttgagatg gagtcttgct ctgtcgccca ggctggagtg cagtggtgtg
     2761 atcttggctc actgcaacct ctgcctcctg ggttcaagca attctcctgc ctcagcctcc
     2821 tgagtagctg ggattacagg cgcctgccac catgcctggc taacttatgt atttttagta
     2881 gagacagggt ttcaccatgt tggccaggct ggtctcgaac tcctgacctc aagtgatcca
     2941 cctgcctcgg cctcccaaaa tgctgggatt acaggcatga gccactgcgt ctggtccttg
     3001 gctgtttctt agccccactc ctggcagtgt ctcttctctt cagctatgac tggggagtag
     3061 atgaccgtgc ttgtttctga cacacagcac agtgtcctct ctgtacacaa gctggtggtt
     3121 caagggccaa tggttccaga gagatagtgg ttcccttcct tccctcctca ccaataggca
     3181 gcctcaggcc ttttctgtgt ataactgtgt atatagacat aaaaacctac aaatgtgaaa
     3241 taaatctatg ctatctttca tagtgttacc acacaaacat ctaaaaggac tacttttggt
     3301 tttgcaatga cagggtcgaa aaaagcccca gatgggctgg attttttttt ttttctgata
     3361 ttttcttcct caaagtccag ttgctctcca agttcctacc cctcccctgc ccttgcctca
     3421 gacctttaag accaaagact gcaaaaccac agtgctgtac ctgccacctc caaggactgg
     3481 cgtcgaggcc caacccagga atgttggctt atttacctcc tgggggaagc agtttaggcc
     3541 tcatcagagc tggggagcac atcccttcag agcccatggg tttcccattc cctcctgtca
     3601 gccctggcca tgaaatcctg gggatctgga gggagggagg atagttagag agtgagaggg
     3661 gcgagggcta gccttttcct aatacccctg ggtttgagtt taatttgcaa taaaatggaa
     3721 tcccagcaca tca
//
