LOCUS       NM_001145011            4017 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens chromosome 16 open reading frame 96 (C16orf96),
            transcript variant 1, mRNA.
ACCESSION   NM_001145011 XM_001715874 XM_296817 XM_940260
VERSION     NM_001145011.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4017)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
REFERENCE   2  (bases 1 to 4017)
  AUTHORS   Martin,J., Han,C., Gordon,L.A., Terry,A., Prabhakar,S., She,X.,
            Xie,G., Hellsten,U., Chan,Y.M., Altherr,M., Couronne,O., Aerts,A.,
            Bajorek,E., Black,S., Blumer,H., Branscomb,E., Brown,N.C.,
            Bruno,W.J., Buckingham,J.M., Callen,D.F., Campbell,C.S.,
            Campbell,M.L., Campbell,E.W., Caoile,C., Challacombe,J.F.,
            Chasteen,L.A., Chertkov,O., Chi,H.C., Christensen,M., Clark,L.M.,
            Cohn,J.D., Denys,M., Detter,J.C., Dickson,M.,
            Dimitrijevic-Bussod,M., Escobar,J., Fawcett,J.J., Flowers,D.,
            Fotopulos,D., Glavina,T., Gomez,M., Gonzales,E., Goodstein,D.,
            Goodwin,L.A., Grady,D.L., Grigoriev,I., Groza,M., Hammon,N.,
            Hawkins,T., Haydu,L., Hildebrand,C.E., Huang,W., Israni,S.,
            Jett,J., Jewett,P.B., Kadner,K., Kimball,H., Kobayashi,A.,
            Krawczyk,M.C., Leyba,T., Longmire,J.L., Lopez,F., Lou,Y., Lowry,S.,
            Ludeman,T., Manohar,C.F., Mark,G.A., McMurray,K.L., Meincke,L.J.,
            Morgan,J., Moyzis,R.K., Mundt,M.O., Munk,A.C., Nandkeshwar,R.D.,
            Pitluck,S., Pollard,M., Predki,P., Parson-Quintana,B., Ramirez,L.,
            Rash,S., Retterer,J., Ricke,D.O., Robinson,D.L., Rodriguez,A.,
            Salamov,A., Saunders,E.H., Scott,D., Shough,T., Stallings,R.L.,
            Stalvey,M., Sutherland,R.D., Tapia,R., Tesmer,J.G., Thayer,N.,
            Thompson,L.S., Tice,H., Torney,D.C., Tran-Gyamfi,M., Tsai,M.,
            Ulanovsky,L.E., Ustaszewska,A., Vo,N., White,P.S., Williams,A.L.,
            Wills,P.L., Wu,J.R., Wu,K., Yang,J., Dejong,P., Bruce,D.,
            Doggett,N.A., Deaven,L., Schmutz,J., Grimwood,J., Richardson,P.,
            Rokhsar,D.S., Eichler,E.E., Gilna,P., Lucas,S.M., Myers,R.M.,
            Rubin,E.M. and Pennacchio,L.A.
  TITLE     The sequence and analysis of duplication-rich human chromosome 16
  JOURNAL   Nature 432 (7020), 988-994 (2004)
   PUBMED   15616553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC023830.9.
            
            On Sep 25, 2020 this sequence version replaced NM_001145011.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.3243909.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144120
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000444310.5/ ENSP00000415027.3
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-570               AC023830.9         26048-26617
            571-675             AC023830.9         41269-41373
            676-756             AC023830.9         44417-44497
            757-843             AC023830.9         44680-44766
            844-2305            AC023830.9         44882-46343
            2306-2391           AC023830.9         48648-48733
            2392-2502           AC023830.9         49723-49833
            2503-2577           AC023830.9         56747-56821
            2578-2742           AC023830.9         57875-58039
            2743-2861           AC023830.9         61374-61492
            2862-2924           AC023830.9         62013-62075
            2925-3017           AC023830.9         62932-63024
            3018-3177           AC023830.9         64059-64218
            3178-3277           AC023830.9         64412-64511
            3278-3358           AC023830.9         68992-69072
            3359-4017           AC023830.9         69808-70466
FEATURES             Location/Qualifiers
     source          1..4017
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..4017
                     /gene="C16orf96"
                     /note="chromosome 16 open reading frame 96"
                     /db_xref="GeneID:342346"
                     /db_xref="HGNC:HGNC:40031"
     exon            1..570
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..3576
                     /gene="C16orf96"
                     /codon_start=1
                     /product="uncharacterized protein C16orf96"
                     /protein_id="NP_001138483.1"
                     /db_xref="CCDS:CCDS53986.1"
                     /db_xref="GeneID:342346"
                     /db_xref="HGNC:HGNC:40031"
                     /translation="MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKK
                     VLSGDEDFLQTSQVVIMPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLP
                     STAQLLEASQGTARPVQDLWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTIT
                     ALRKEVDMLKNMLDKVHPERMDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDM
                     VLWSGLHDAMFTSEIGSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQL
                     LQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEP
                     VPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRR
                     WPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQ
                     LAAVQVKGEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDV
                     PKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEAQPKAPQSALHRLKT
                     TAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGPLGVFADVL
                     GAGPSRGATESQILGDDSEIYEILSPSYSAASIGPDPALSQAMVATKQAMSPEDKKRA
                     VKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLANMGGPSSLGTTVDILQKKIGS
                     LQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRMDEFKTLQAQIKRLEMNKV
                     NKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGILFKVTIHEDSWKKAMEE
                     LSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAAGFRRKLFKRVKCIS
                     CDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQWLQLQDLGIQEDC
                     QQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGILYKGRVNSQR
                     GAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTM
                     PARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPANP"
     exon            571..675
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            676..756
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            757..843
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            844..2305
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            2306..2391
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            2392..2502
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            2503..2577
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            2578..2742
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            2743..2861
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..2924
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            2925..3017
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            3018..3177
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            3178..3277
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            3278..3358
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     exon            3359..4017
                     /gene="C16orf96"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3952..3957
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C16orf96"
                     /note="hexamer: AATACA"
     polyA_site      3971
                     /gene="C16orf96"
                     /note="major polyA site"
     regulatory      3993..3998
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C16orf96"
                     /note="hexamer: TATAAA"
     polyA_site      4017
                     /gene="C16orf96"
                     /note="major polyA site"
ORIGIN      
        1 agaacagagg ccattcctcc ctgactgctg tgactcacca ccaccccagg cctctgagga
       61 ccagtccatg tagctctcgg aaccactgaa agctacccct tgtccttgag gacacctgga
      121 accccagccc cactgaccca ccctggcagg atgagcttct cactcacgtt caccgagctg
      181 gccaacatcg ccatcccaca gtgcggggtg ctgaacttca aggccctgca cctcctgctg
      241 cacggcatct tggagcacat ccacatggcc gagctcaaga aagtcctctc aggcgatgag
      301 gacttcctgc agacctcgca ggtggtcatc atgcccaggg aaggagacgc ccagcctatc
      361 ctcaacccca tgaagaggct cagcaatgtc ttcgaccacg tggtgagccg cctcgacaag
      421 ttggagaacc agctggccct gctgcaggac ctgccctcca ctgcccagct gctggaagcc
      481 agccagggca ctgcccggcc cgtccaggac ctgtggcatc tgatcaagct ccggaagatg
      541 gtggagggtc atgatgaagt catggccaag tcaatgcaga ccctgcagga cttgctcact
      601 gatcttcatg cactccaggt caccatcaca gccctcagaa aagaagtgga catgctgaag
      661 aacatgcttg acaaggtaca cccagaaaga atggacatct ttgctgaaga cttcaaaata
      721 cagaactgga agatggttgc actgcagcgg gaagtggctt ctctccagaa taagtttaaa
      781 accatcccca aaaccgagga catggtgctc tggagtggcc ttcatgatgc catgttcacc
      841 tcagaaattg gttcatcacc actggacctg tggcagtctg tagagcagct cccagaggct
      901 gccctggccc agaccaccaa gtaccttgaa gctactcgtg ccatccaggt ctccgagccc
      961 gtccaaaacc cccagctact gcagactgtc tggcattatg aggtcccaga gctcctcccg
     1021 gagggctcat ctgcccaagc agtttcactc agcagagccc aggagccagc gcagcctccg
     1081 gccctcacgc ctgagtctgc acctgggtgc acaactgaat ttgcacctgg gcctgcacct
     1141 gggactgaac ctgtgccagg actggagctg gggctggagc tggagcctgt gcctgccctg
     1201 gggcctgtcc cagggcccag tgtgacacct gggtccttgc cagcaccttg gcctgtgctt
     1261 ggacctgtgc ctgccccagg tgcccagcct ccaccactgg gagactggcc tgcactccca
     1321 agacgctggc ctcttcccca aggctggccc agggtgggct cttggcctct gtgggactta
     1381 ggtgtcctgc ggccaactca gccccaaccc tccagggccc caccaccagc cactgagttt
     1441 ggctcattgt ggcctcgacc actccagcca tatcagtctc gccagggaga agccctccag
     1501 ctcgcagctg tccaagtaaa gggggaggaa aatgatgtcc ccagcctaag gggccttcgg
     1561 gagagggccc gcaaggatgg ggcccccaag gatagaactc gcaaggatgg ggtccccaaa
     1621 gatagaggtg gcaaggatgt ggaccccaag gatagagctc acaaggatga tgtccccaaa
     1681 gatagaggtg gcaaggatgt ggaccccaag gatagagctc acaaggatga tgtccccaaa
     1741 gatagaggtg gcaaagatgg ggaccccaag gatagagttg gcaaggatgg ggcccccaag
     1801 gaagcacagc ctaaggctcc ccagtctgcc cttcaccggc tgaaaaccac cgctgccatc
     1861 gccgccgctg ccgccgcagc ctacgccgct gccacatcct ccgctgccca ggcagccaaa
     1921 gttgctgcca agtttgtcaa ggatgcccca gccaccaaaa tggccgccat tgcaacagac
     1981 acggctgcag ctgggcccct aggggtcttt gcagatgtcc tgggtgcagg gccttcccgg
     2041 ggagccacag aatcccagat cttgggcgat gattccgaaa tctacgaaat cctctctccc
     2101 tcctactctg ctgccagcat cggtcccgat ccagccctgt cccaggccat ggtggctacc
     2161 aagcaggcca tgagccctga agacaagaag agggctgtca agtattccat gagccacata
     2221 gcccagatac ctgtcaaaca cgactctctg aaggaagaat ttgcccagct gtcctgtaac
     2281 ctgaaccagc gcttgagtta tctagccaat atgggaggtc cttccagcct cgggacaaca
     2341 gtggacatat tgcagaaaaa gattggcagc ctccagaaat ctaggctcaa ggaggaagaa
     2401 cttgagagaa tttggggcaa ccaaatagag atgatgaagg atcgctacat cactttggac
     2461 aaggcggtgg agaacctgca gattcgcatg gatgagttca agactctcca ggctcaaatc
     2521 aaaagactgg aaatgaacaa ggtgaataag agcacgatgg aggaggagct gagagagaaa
     2581 gctgacagga gtgccctggc aggcaaggca agccgcgttg acctggagac tgtggccttg
     2641 gagctgaacg agatgattca gggcatactc ttcaaggtca cgatccatga ggacagctgg
     2701 aagaaggcta tggaggagct cagcaaggac gtgaacacca agttagtcca cagtgatctg
     2761 gatcccttga agaaagaaat ggaagaggtc tggaaaatcg tccggaagct gctgattgag
     2821 ggcttaagac tggatcctga cagtgctgct ggctttagga ggaagctgtt caagcgcgtg
     2881 aagtgcatct cctgtgaccg gcctgtggag atgatgactg gcccacagct gatcaccatc
     2941 cgcaaagccc acctgctgtc ccggctgcgg ccagccagcg ccaacagctg cgagtacttg
     3001 cagcggcaac agatgaggga acagcagtgg ctgcagctcc aggacctcgg tatccaggag
     3061 gattgtcagc aggactgggg tgatggcccc caaaacgcca ccagcctcaa gtgcaagtcc
     3121 tgcaacctgt tgacgctcta tccctacggg gatccccacg tgatcgacta tgacagcgcc
     3181 gaggtggaca tcctgggcgt ggatgggatc ctgtacaaag gccgcgtgaa cagccagcgt
     3241 ggggctcagc ccttggccgt cgcaaaggag ctggcagctg tgaaggctcc atctcccccg
     3301 tcacaaagcc tgtatgaccg tgtgcactcc agtgccctat ttggcgccat ctgccccccc
     3361 ctgtgccccc gctccagtgc ctgctcagct gcctcgggcc ctcacctgac gatgccagct
     3421 cgaccacctt ccctgccacc tctgctgctg ctgccaccgc tgattccatc cctaagggac
     3481 ccccagcagg ccccagggtc caccaggctc tcaagagctc cacacattga gtcccgagtc
     3541 ggcaggaagc cccccgagga gcccgccaac ccgtgagccc caccccgctg cgccccccat
     3601 cgccaagtcc cctccacgtc cgaggctgag gcccatgtgg ccctcccact cccaccaagt
     3661 cccctccaca tcggaggctg aggcctatgt ggccccccac ccccaccccc accaagtccc
     3721 ctccatgtcc gaggctgagg ctcatgcgcc cccccccatc cctaccaagt cccctccacg
     3781 tccgaggctg agacccatat gcccccccca cccccaccaa gtcccgtccc cggctgagac
     3841 ccagggccct gagcctggcc cagaaagggt gctggggccc tggatagagg ggaggggtct
     3901 gtgtagggga cccccatgct gacccagtgg ctgttttatc ctgtgcatat aaatacaaac
     3961 agcacagtgc acattctcat tctacattgt catataaaca cagctttcta gagtgaa
//
