LOCUS       NM_001012984            1266 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens chromosome 16 open reading frame 86 (C16orf86), mRNA.
ACCESSION   NM_001012984 XM_370984
VERSION     NM_001012984.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1266)
  CONSRTM   Schizophrenia Working Group of the Psychiatric Genomics Consortium
  TITLE     Biological insights from 108 schizophrenia-associated genetic loci
  JOURNAL   Nature 511 (7510), 421-427 (2014)
   PUBMED   25056061
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010530.8, BC032064.1 and CA432406.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001012984.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.657716.1,
                                           SRR3476690.902001.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000403458.9/ ENSP00000384117.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                AC010530.8         135057-135079       c
            24-726              BC032064.1         1-703
            727-1266            CA432406.1         22-561              c
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.1"
     gene            1..1266
                     /gene="C16orf86"
                     /note="chromosome 16 open reading frame 86"
                     /db_xref="GeneID:388284"
                     /db_xref="HGNC:HGNC:33755"
     exon            1..259
                     /gene="C16orf86"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..1111
                     /gene="C16orf86"
                     /codon_start=1
                     /product="uncharacterized protein C16orf86"
                     /protein_id="NP_001013002.2"
                     /db_xref="CCDS:CCDS32468.2"
                     /db_xref="GeneID:388284"
                     /db_xref="HGNC:HGNC:33755"
                     /translation="MASAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLV
                     PAHEARGTQSEDQRPAGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPR
                     HGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRK
                     SLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEA
                     EAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVTPTHALAPLGEEAGEEPGG
                     LPSLGVSDHKAEVDKSTQVDIDKMLSVCTAPLVPPLSPQYK"
     exon            260..489
                     /gene="C16orf86"
                     /inference="alignment:Splign:2.1.0"
     exon            490..710
                     /gene="C16orf86"
                     /inference="alignment:Splign:2.1.0"
     exon            711..1266
                     /gene="C16orf86"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1244..1249
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C16orf86"
                     /note="hexamer: AATAAA"
     polyA_site      1266
                     /gene="C16orf86"
                     /note="major polyA site"
ORIGIN      
        1 gtagtttcgg ccgagggtgg gctccgcggt cgccggtttc tcttcccagc tctgccctcg
       61 cttgctggcc ggtctccggg gtcagcgcgg ggccaccatc cagccccttg gggcccgccc
      121 caagcagctg tcgaggacgc actcagcctg cgcagccatg gcctcggcag gggcggagag
      181 gcggccgggg gtccaggagg cgacggtcgt ggggcaggga cagctcacgg aggagcccgg
      241 cagcgctcag acctccgagt gtccagtggc gggagaccag ttcctggtgc ctgcccatga
      301 ggcccgcgga acccagagtg aagaccagcg cccagcaggc gcagcttcgg agtcggagct
      361 ccaggaggaa ggacccaagc tgggggagga gcggcccaag ccgcatgccg gggcgctaga
      421 ggagagaggc cccaggcccg tggtctccat tgtgaggccc cgtcatggtc caaagagaaa
      481 gcctgtcaag tctctcagcc tcccgggcct tcgtgcccat cttaaggctg aagctgagct
      541 gccacccaag ctgccgctgc aggaggagga gccagaggac agccagagtg agccctcacc
      601 atctgccaaa cagcacaaaa aagccaagaa gcgcaagagc ctgggggctc ccgtgctcca
      661 cgctgtggcc agcatggtgt ctgcaccctt agagacattg aggctggagc gaaaggccca
      721 gcgcctgcgg ccgctgtacc agtacgtcaa ctattgcaac cctgagctga accaggcagg
      781 gaagggggac ggggaggctg aggtggaggc agaggcagag ctggccccgg ttcccgagga
      841 gggaggtgtg gagcaactgc aggccttgct gcccttggca ggtgagctgg gcccaggcct
      901 cgctttgccc tgtcccagtc cactagtgac ccccacccat gccctggctc ccctcggaga
      961 ggaggctgga gaggagcctg ggggcttgcc cagcttgggg gtgagtgacc acaaggccga
     1021 ggtggataag tcaacccagg tggacatcga caagatgctg agtgtctgca ctgctccact
     1081 tgtccccccg ctctctcctc agtacaagtg actgtcccgc cccactggtg gctcccctcc
     1141 ttccacgcct gaatttggct tcaggcttcc tgtgggccta ggccctctgg tggcgggggc
     1201 aaatttggca cctgccccca cttgggactt tggtcttgct gaaaataaat atttttcttt
     1261 ttcaaa
//
