LOCUS       NM_144602               1087 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens chromosome 16 open reading frame 78 (C16orf78), mRNA.
ACCESSION   NM_144602
VERSION     NM_144602.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1087)
  AUTHORS   Tao,S., Wang,Z., Feng,J., Hsu,F.C., Jin,G., Kim,S.T., Zhang,Z.,
            Gronberg,H., Zheng,L.S., Isaacs,W.B., Xu,J. and Sun,J.
  TITLE     A genome-wide search for loci interacting with known prostate
            cancer risk-associated genetic variants
  JOURNAL   Carcinogenesis 33 (3), 598-603 (2012)
   PUBMED   22219177
REFERENCE   2  (bases 1 to 1087)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007614.7, HY001804.1, BC021181.2 and AI478870.1.
            
            On May 17, 2019 this sequence version replaced NM_144602.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.259636.1,
                                           ERR279839.6122.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000299191.4/ ENSP00000299191.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AC007614.7         57970-57973         c
            5-98                HY001804.1         1-94
            99-1066             BC021181.2         6-973
            1067-1087           AI478870.1         22-42               c
FEATURES             Location/Qualifiers
     source          1..1087
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q12.1"
     gene            1..1087
                     /gene="C16orf78"
                     /note="chromosome 16 open reading frame 78"
                     /db_xref="GeneID:123970"
                     /db_xref="HGNC:HGNC:28479"
     exon            1..286
                     /gene="C16orf78"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..934
                     /gene="C16orf78"
                     /codon_start=1
                     /product="uncharacterized protein C16orf78"
                     /protein_id="NP_653203.1"
                     /db_xref="CCDS:CCDS10738.1"
                     /db_xref="GeneID:123970"
                     /db_xref="HGNC:HGNC:28479"
                     /translation="MSEQQMDLKDLMPTKRKYMWKTAEDRRMSDLTCVLEWLERRQGK
                     KKQAPEKQKPKVVTVLKRNKKKEEKKGKGLMTARGGNRRDTETSQQALGKRFRKDAAS
                     YRSLYGVEQKGKHLSMVPGSYIKDGPKKSDTDIKDAVDPESTQRPNPFRRQSIVLDPM
                     LQEGTFNSQRATFIRDWSNKMPDMAYERKLKSLMEKSTEPKMETMRMLKPEEVLSCRY
                     LRLSKENIRTLLKLCKDAGMNVDIHPHMVEEDIDAKKVFTGIPSMAL"
     exon            287..406
                     /gene="C16orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            407..530
                     /gene="C16orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            531..786
                     /gene="C16orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            787..1087
                     /gene="C16orf78"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1065..1070
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C16orf78"
                     /note="hexamer: AACAAG"
     polyA_site      1069
                     /gene="C16orf78"
                     /note="major polyA site"
     polyA_site      1087
                     /gene="C16orf78"
ORIGIN      
        1 actctgccct ttatgttcac atctggaggc cacaccctac cttctaagtc accaggccat
       61 caagtccaga caaagggatc gaaagagtga gacagtgcca gccacctccc acccaagcca
      121 ctagcaagac tccacaatgt cagagcaaca aatggacctg aaggatttaa tgcccacaaa
      181 gaggaaatac atgtggaaga ctgctgaaga taggcgcatg tctgacctca cctgtgtgct
      241 ggagtggctg gagcggaggc aggggaagaa gaaacaagct cccgagaagc aaaagcccaa
      301 agtggtgaca gtccttaaac gaaataagaa gaaggaagag aagaaaggca aaggcctcat
      361 gacagcacgg ggagggaacc gcagggacac ggagacttcc cagcaggcct taggaaagag
      421 attcaggaag gacgccgcct cctaccgaag cctctatgga gtggagcaaa aggggaaaca
      481 cctcagcatg gtccctggca gctacatcaa ggatggcccc aagaaatctg atacagacat
      541 caaggatgca gtcgacccag agtccactca gcggccaaac ccattccgtc gacaaagcat
      601 tgtcttagat cccatgttac aggagggtac ctttaacagc cagagggcaa ccttcataag
      661 agactggtcc aacaagatgc ctgacatggc ttacgaacgc aagctaaaga gcctcatgga
      721 gaaaagcacc gaacctaaga tggaaaccat gaggatgttg aagccagagg aggtgctgag
      781 ctgccgatac ctgaggttat ccaaggagaa cattcggacc ttgctcaagt tgtgcaagga
      841 tgcaggaatg aatgtggata tccaccccca catggtcgaa gaggacatag atgctaaaaa
      901 ggtgttcacc ggaataccca gcatggccct ctaaatagct cctctcgcca ccaccttcag
      961 gctccttctg tcatgggacc cttcacctcc agatgccatc ctctggcaca ctacaagtgg
     1021 tccttccaac ttagtgcatc cctttagaaa gtaagcaatc agaaaacaag cctcggctgt
     1081 gtgatca
//
