LOCUS       NM_001017923            2935 bp    mRNA    linear   PRI 07-JAN-2025
DEFINITION  Homo sapiens dopamine receptor interacting protein 1 (DORIP1),
            mRNA.
ACCESSION   NM_001017923 XM_005267315 XM_071793
VERSION     NM_001017923.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2935)
  AUTHORS   Yang,X., Hu,Y., Liu,Y., Liu,W., Zhao,X., Liu,M. and Tang,H.
  TITLE     C14orf28 downregulated by miR-519d contributes to oncogenicity and
            regulates apoptosis and EMT in colorectal cancer
  JOURNAL   Mol Cell Biochem 434 (1-2), 197-208 (2017)
   PUBMED   28455792
REFERENCE   2  (bases 1 to 2935)
  AUTHORS   Zhan,L., Kerr,J.R., Lafuente,M.J., Maclean,A., Chibalina,M.V.,
            Liu,B., Burke,B., Bevan,S. and Nasir,J.
  TITLE     Altered expression and coregulation of dopamine signalling genes in
            schizophrenia and bipolar disorder
  JOURNAL   Neuropathol Appl Neurobiol 37 (2), 206-219 (2011)
   PUBMED   20874815
  REMARK    GeneRIF: our data suggest: (i) C14ORF28, GNB2L1, MLLT3, DRD2 and
            DARPP-32 are important in the pathogenesis of schizophrenia and
            bipolar disorder
REFERENCE   3  (bases 1 to 2935)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL049870.3, BM849739.1 and BU624091.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001017923.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.190362.1,
                                           SRR1660807.250020.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000325192.8/ ENSP00000326846.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AL049870.3         48324-48352
            30-526              BM849739.1         10-506
            527-1190            BU624091.1         19-682              c
            1191-2935           AL049870.3         56562-58306
FEATURES             Location/Qualifiers
     source          1..2935
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q21.2"
     gene            1..2935
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /note="dopamine receptor interacting protein 1"
                     /db_xref="GeneID:122525"
                     /db_xref="HGNC:HGNC:19834"
     exon            1..294
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /inference="alignment:Splign:2.1.0"
     exon            295..819
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             296..1228
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /codon_start=1
                     /product="uncharacterized protein C14orf28"
                     /protein_id="NP_001017923.1"
                     /db_xref="CCDS:CCDS32069.1"
                     /db_xref="GeneID:122525"
                     /db_xref="HGNC:HGNC:19834"
                     /translation="MKTLFEEIKASIKNNYNQDRSFCRPVLPWGGVFTIKAGRKAVSC
                     TPLYVEIRLKNTCTIDGFLMLLYVILNENENFPRELSLHFGREFVDCFLYLMDTYSFT
                     TVKLLWIWDKMEKQQYKSEVHKASLIIDLFGNEHDNFTKNLENLMSTIQESYCSNWRC
                     PTRVQEDQQRTININPPQEIPHGNLIRLAVNELFCSKIELCEEHGCGGLREFSQRIFC
                     HGAPPFVVLNMQHWKSEDLAYVPYYLDLSDHKYLLEGATLFNKEEHHYSAAFQIGGHW
                     MHYDGLRNVNLILLNKPPEFLLLSSLVYIRATEK"
     exon            820..909
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1044
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..2935
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1228..1233
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /note="hexamer: AATATA"
     polyA_site      1247
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /note="major polyA site"
     regulatory      1462..1467
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /note="hexamer: AATAAA"
     polyA_site      1481
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /note="major polyA site"
     regulatory      2901..2906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
                     /note="hexamer: AATAAA"
     polyA_site      2935
                     /gene="DORIP1"
                     /gene_synonym="C14orf28; c14_5270; DRIP-1; DRIP1"
ORIGIN      
        1 ggaggtcgtg ccgaatcttc ctccgtaata agaagcgacg tgtcccactg tcctggctcc
       61 gtgggtccag tgagattggg cctgggcgct ggagctgctg tggctcccgc cgcggcggct
      121 gccatggagg ccatgccaga gcccagaact cacgccgggg gaggccgaga cagccggcgg
      181 tactcataga tgaggcagcg gcggcggcgg cggcggcggc agcccgggct ctccatgagc
      241 aggcggcggc ggcgacgggt gcggcggcac cggcagtttt cggtccccag ggaggatgaa
      301 gacactgttt gaagagatca aagcatcaat taaaaataac tataaccaag atcgatcatt
      361 ttgtaggcct gttcttcctt gggggggtgt ttttactatc aaagctggcc gcaaagcagt
      421 atcctgtaca ccactctatg ttgaaataag actgaaaaat acctgcacca tagatggatt
      481 cttgatgtta ttatatgtca ttcttaatga aaatgaaaac ttccctaggg aactctctct
      541 tcattttggt agagagtttg tagactgttt tctttactta atggacacct acagttttac
      601 aactgtgaag ctactttgga tttgggacaa gatggaaaaa cagcaataca aatctgaagt
      661 ccataaagct tcattaataa ttgatttgtt tgggaatgag catgataatt ttacaaaaaa
      721 tcttgaaaat ctcatgtcta ccattcaaga gagttactgt tccaactggc gatgcccaac
      781 tcgagtgcag gaggatcagc agcgcacaat taatataaat cctccccaag aaattccaca
      841 tggaaacttg ataagactgg ctgtgaatga gttattctgt tccaagattg aactgtgtga
      901 agagcatggg tgtggtggct taagagaatt ttcccaacga attttctgcc atggggcacc
      961 cccttttgtt gtcttaaata tgcaacattg gaaatctgaa gatctggcgt atgtacccta
     1021 ttacttggat ttgtctgatc acaagtattt gttggaaggt gccacattat ttaacaaaga
     1081 ggaacatcat tattctgcag ctttccagat tggtggacat tggatgcact atgatgggct
     1141 cagaaatgtg aatttaattt tgttaaataa acccccagag tttctcctct tgtcatcatt
     1201 ggtttatatt cgagcaacag agaaataaat atagattgat gctaaaagtt gttttccctc
     1261 ctgcccatgc tctcccagat gaagggcttt tattttgtgt atacttggta tccaagaaaa
     1321 tagttcaact atactagttt cagaagtgta ttttcagtgt ttaaccccag gtaaatgttt
     1381 tatatagagg atctgtgcaa aaatgtttgt aattttttta tatttcctga gttattttta
     1441 tatgagcata ttttatgttg gaataaaata tatcttgtgg cctttgtatt ttttatttat
     1501 atgtacctca aagattttta caattctgtc tttgaattca agaaatactt tgtcatctga
     1561 attctaaatt tttctttttg gatattcgag taaaacctag gtaaaagtat tttaagttta
     1621 tataatttaa cagttcaaaa tatatctgac tgtatttctt tgccctacct cactataatc
     1681 caaagtgcac tatttgatct agtatggatt tgaatgtaca atttatcgat ggcttagttt
     1741 attagttcga tttgcctagt atccctgcag caatttttta aaatgtctga gaaatttttc
     1801 agagcttaaa ctatttcttt ataatggcaa attactttta actacttcct aaagtattat
     1861 aaacctgcca gtggatttta agtgatagct aagcttccaa gcttaattca cgttattaca
     1921 aataaattat ataactatct taaatgttta tcttataatt aaatgtaatt tgaaatgctc
     1981 taatgtattt tgcagataaa acaactataa acaatattag gcaactggat gtttactagt
     2041 gtcggactag caatagaaat gcactttaaa tatatattta aggggaaatg cgtgcctgga
     2101 aatacttctt ttcctagtga agttttatat tgacacagag aaaagaatac ttaaaatttt
     2161 gagtgatgtc tactggcttc cttgtaagta gtgattgata gcatgcggct ttgacttgca
     2221 atacaaatca ttacgatttt atagttatca gaacattacg tttctttata aagaccctaa
     2281 ggtcactctt ctttttgcaa cttaagggaa aaaatattct caagggaaaa tactttttga
     2341 aatttatcac cattttagtg tttacatttc aataaatagt tcacttcagg tttgggattg
     2401 agattagttg caatatattt agaagctcct acatgacagc acagatcact gccatctgct
     2461 gaactgctaa agtgcttggt gccatgttga gaaaacttac ccaagaatgg ataaatatgg
     2521 gtgaaacatt actgagaatg cctcacgtta gcaaatacta tgaaaattct tgtttatata
     2581 tcaaactgat ttattttaca aaaaaaaaaa attcacccca agatttattt agtttcccaa
     2641 gtgtatctga ttaggattta atttagagta aacttttctg gggacacctg attgcatgaa
     2701 ctgaagtata caataacaca aatattacag taaacataaa tggtgtcatt aacaaaatta
     2761 ttcctaatgc agatttattc tttcaggaaa tgcactttat ttggaatact agtttatcat
     2821 gaaacaatga cttacctacc tcacagggtt gttgtgagga ttaagatgtt tgttaaaatc
     2881 ttgactacct tgaacatgct aataaaaaaa catttttcta cctcttttat ttgca
//
