LOCUS       NM_001252507            7627 bp    mRNA    linear   PRI 28-JUL-2023
DEFINITION  Homo sapiens chromosome 14 open reading frame 132 (C14orf132),
            transcript variant 2, mRNA.
ACCESSION   NM_001252507
VERSION     NM_001252507.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7627)
  AUTHORS   Tiirats A, Viltrop T, Noukas M, Reimann E, Salumets A and Koks S.
  TITLE     C14orf132 gene is possibly related to extremely low birth weight
  JOURNAL   BMC Genet 17 (1), 132 (2016)
   PUBMED   27660052
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7627)
  AUTHORS   Oshikawa M, Tsutsui C, Ikegami T, Fuchida Y, Matsubara M, Toyama S,
            Usami R, Ohtoko K and Kato S.
  TITLE     Full-length transcriptome analysis of human retina-derived cell
            lines ARPE-19 and Y79 using the vector-capping method
  JOURNAL   Invest Ophthalmol Vis Sci 52 (9), 6662-6670 (2011)
   PUBMED   21697133
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC043593.1, AL137190.5, CA434364.1 and DB264577.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001252507.2.
            
            Transcript Variant: This variant (2) lacks a portion of the 5' UTR
            and 5' coding region, and uses an alternate translational start
            codon, compared to variant 1. The encoded isoform (b) has a
            distinct N-terminus and is shorter than isoform a. Both variants 2
            and 3 encode isoform b.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.190302.1,
                                           SRR1803612.204036.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000555004.3/ ENSP00000490729.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-757               BC043593.1         22-778
            758-7110            AL137190.5         52702-59054         c
            7111-7545           CA434364.1         17-451              c
            7546-7627           DB264577.1         391-472
FEATURES             Location/Qualifiers
     source          1..7627
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.2"
     gene            1..7627
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /note="chromosome 14 open reading frame 132"
                     /db_xref="GeneID:56967"
                     /db_xref="HGNC:HGNC:20346"
     exon            1..166
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /inference="alignment:Splign:2.1.0"
     CDS             140..391
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /note="isoform b is encoded by transcript variant 2"
                     /codon_start=1
                     /product="uncharacterized protein C14orf132 isoform b"
                     /protein_id="NP_001239436.1"
                     /db_xref="CCDS:CCDS81848.1"
                     /db_xref="GeneID:56967"
                     /db_xref="HGNC:HGNC:20346"
                     /translation="MDLSFMAAQLPMMGGAFMDSPNEDFSTEYSLFNSSANVHAAANG
                     QGQPEDPPRSSNDAVLLWIAIIATLGNIVVVGVVYAFTF"
     exon            167..7627
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5762..5767
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /note="hexamer: AATAAA"
     polyA_site      5786
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /note="major polyA site"
     regulatory      7425..7430
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /note="hexamer: ATTAAA"
     polyA_site      7457
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
     regulatory      7533..7538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /note="hexamer: AAGAAA"
     polyA_site      7545
                     /gene="C14orf132"
                     /gene_synonym="C14orf88"
                     /note="major polyA site"
ORIGIN      
        1 agaagcccag agacagccga gtgcgccgtg cggtctccgg acgctcgctg ctcagcccga
       61 tccccgccaa ctgtgcaggc ggctgacccg cagcggcagc ggcagcagcg aggactcgag
      121 cgctggctgc agcgacacca tggatctctc ctttatggcc gcgcagctgc ccatgatggg
      181 gggagctttc atggactcgc ccaacgagga cttcagcacc gagtactccc tgtttaactc
      241 ctctgccaat gtccacgcgg ctgccaatgg ccagggccag ccggaagatc ctcctcggtc
      301 ctccaacgac gccgtcttgc tatggattgc catcatagct acgctgggga acatcgtggt
      361 ggtgggcgtg gtgtatgcct tcaccttctg aggacggcac accctgcacc accatggggt
      421 gaggcttggc acgtagctct gacttgctgt cggcctttgg cttctcctgt gttctagaac
      481 caggagtttt gaccaggggc ggcggccgtc cttctggaat ttctccccag cagccctgat
      541 ttcaaatatc ccatgttgtg gtcaagctga gtcagaagac atggaagtat gggcctcctg
      601 cccctagagg catgacgggg caaggccttc agagggcaga ttggggatcc ttgaaactac
      661 attccaggaa catgggacca gatgagacag ctagttaagt ttaaaacata gacatgattt
      721 gatgatcgct tgctggtggt aaataatcac tcgtgtgtct tgtttttatg caaacttatc
      781 gaacctaggg cgtggggtgc tggggcaaga gcagccctca gaacttcagt gttcctgacc
      841 caattctggt ttcacattca gtcccttggc catctagtag ggccattgga tgttcctagt
      901 ttgactttga aatggcacct ttgccaccag acacctggtc ccttccaaga cccaagtgca
      961 ttgggagacc cagggatggg gggttactgg taataggtgg ggtttctggg ggtgttgttg
     1021 gtggttttta tctcctggtc ggactttctc ttctttttaa gaagaggaga ggatgtcttt
     1081 aagagctaga tgtgccaggc agtggactct tcaggccacc cacgtgagaa tgctgtttct
     1141 tctctgagga atcgtggaat tttaaagatg aacaagattc acatccactg aattattcaa
     1201 cggatgggtc agaaaggggg gtgatttgcc tgtggtcacc aggcaggttt gtggaggagt
     1261 cggaacagaa agatgtgtcc tcactctcag ctcactgagc tctctgcccc aactaagcac
     1321 ttccctgagg aggttgctga gaagctgccc tcaggagaat gtccaggcat cttgaaggtg
     1381 ggtgcgagat tggcaggctg ctcagatacc cgtcctttac attcagtgtg gataccgtgc
     1441 attctcctga agctgtgaaa gtgcttctgc ccaagccact tccttaaatt ctgaaatatc
     1501 agcatctggg gtcctggcaa gcaaggaagc ttccaagtaa aaaccagaga gaagggcaca
     1561 cttttctttc ttcattagga aatcttattg cacaggaacc acccccaccc ccacccccca
     1621 caccttccca aggcagcatc ccagtgcaga tagagtggga aaggtcccag aagggggctc
     1681 actcacctct aggcccagag aggctttctc ctcactttat acactgcaaa aacagaagaa
     1741 ttgtgtcaat aacaccctct gtagtggaga aacttaaaaa gctggttagg aagctctcgt
     1801 gtatatttag agacaattac aagaaagctg gacttgccgc tgtggtctca ggagaaatga
     1861 gtgttcttga tgacaggcaa agggacatct tagttgtcca gaagcggcac tcttccctgg
     1921 aagccgccat gttaatagga ttactagcct ggctccagac agtgcctgct catggctgcc
     1981 agttcttacc gatcacatct gtcactgcca ccgtatatca tctgccagtg catcagctta
     2041 aggggaggtc acgagtgcaa aagaacctga cccttgacaa tgagggagaa gggacatgga
     2101 ccacctgtct ggaattcctg gaatcactgg cagggtggag gctgggctgg ggagttagcc
     2161 gcggtgtgcg tgaatggctc tgtctccagc aagtctctct ccatcaaacc ccaggtctgc
     2221 cccataagca agatctttaa cagatggatg tctccatgag aaaacccaag gcgagaagcc
     2281 cagagccatg gcggggttgc ttgacgtcct catggagtca ctctgcccca catgctcaaa
     2341 tcttccctct ggccccacat ccctaggagg gcctgacccc tgtaaagata caggaggcag
     2401 ctccctggcc tccaaatggc ccatggagat ggcagtcggg agacagggtt ctgtgtttgc
     2461 tgcggtgaag ggaggagaag gcaggaggaa aaaggatggc ttctagccct gaagaggact
     2521 ccagcatccc aggcaccggg tgcttctggc tgcagttttc cctatggagg cccctcagcc
     2581 tccagcccta acataaatgt cggttaaatt cagttttcaa gcctctctcc cttttcagtg
     2641 tcagagcagt agatggtcca gggcattgga ggcctcgacc actctgcatt gcagattaca
     2701 gtgacttcct cggggttgcc ccatcttggt ctcctgtggt ttcttcatca gctttttttt
     2761 taccagcatc tctcaaataa caatgaagat agatatgccc attagtgtct gattaaggag
     2821 caaaggctgg atttctggcc acagcgagct gcactctccc tcctgcctca gccggggtcc
     2881 gtcttagcag tttggaaagg ggaaaaagat gccggtcctc actgcttaag ttttgtgtcc
     2941 aggtgccact agacttgcat gcacactaac tccttacaat caccacacag catcatcgcc
     3001 ccagtgcaca gatgaggaac cagaggctca gaggagtgaa gttgccttcc tgaggtcaca
     3061 cagcatgaaa gtgatgagct aggatttgaa tctgggaagt tgggctctag agccagactg
     3121 tactgccttc tgccacactg tactgccttc tgtgactggg tggcacctcc agggcacatt
     3181 tacacaaggc cctgaatctg cagaggctgt ttctcaagat gcccgtcatg gtgtggcctg
     3241 ggccagctct ggcttccaca ggtccctgac tgtcctcaga gtggaacatg ctcaacctcc
     3301 cgcccactgc tctctctctg cccagatttc aggggtgccg gtccccaagg cctgccccct
     3361 tctttaagac tgaactcaag tctccttgga aggccccggt gaagctccca gagactggtt
     3421 ttcttgggat gcaggcagaa ggggaccctc cctggccaac acccaggagc ccagcagaag
     3481 cacccacacg tagaaagagg ctcactacag ccagaagtgc agagtcagag tcctgggacc
     3541 atcttgttct gcaaggtgac cccaggctcc ccaggacagg ggagagggat cgtcctcatt
     3601 cagactctag ctggggcctc tgtactggct tctccctggg tggggttgcc tgttacatag
     3661 ctgtgcctca gagaaagggt cctgcatttt ctggaatgtt ctctgtgctt acccctctgt
     3721 gtgcccctcc attgctcctc tacaagcaat taggtgattc aaaagagcaa cttaggctgg
     3781 gtgcagtgac tcacacccgt aatcccggca ctttgggagg ccgaggcggg cagggacagg
     3841 agttcaagac cagcctggcc aacatggtga aaccctgtct ctacaaaaaa tacaaaaatt
     3901 aaccagacat tgtggcatgt gcctgtaatc ccagctactc aggaggctga cacaggagaa
     3961 ttgcttgaac caggaggcgg aggctgcagt gagctgagat tgtgccactg cactccagcc
     4021 tgggcaacag aacgagactc tgtctcaaaa aaaaaaaaaa agaaaagaaa aaaaaaaaga
     4081 gcaacttact gctttgtgag gttgtgagtg gccaccactg aaggtctttg agaagaggcc
     4141 agacgccgct gtagccaggc ctgtcttaag aggacttgtg cttccaggga cccaggcagg
     4201 atgatggcgc agctcttcct actccaagcc aatgctgtcc ttcccctttc ccatgaaatc
     4261 aaggtcaaga ggcaaataag actccctgct ccactctacc ccccagagag aaatgattct
     4321 cgctcctttc agatccccca ggatctgagg gagaaaggat gggaggaggg gcagcagcat
     4381 ttcgctggaa aggcagcaga tgcttttcca gccccggttc agctggaagg cttggaggct
     4441 ggccagacca ctctggcgtc tcctgaagtg ggtccctgga gaccgaagag gctcagtgga
     4501 gtctgtctgt tgtcagcact gctgcctgat ccctgcaaga caaatggcac tttccttctt
     4561 cagaagcatc atctgccttc attattagca gtaatattat tcccagttat tattcttacc
     4621 ggtgccagtt ttgcacatct ttttgttgct ctatttgtgt ctcatttact tctcaaattg
     4681 cccctggggg caggaatgag gatgcagaga gatgcacgtt aattactgtc gcatttttct
     4741 gtggagaaaa ctgaggccag ggctgaacgc tcacagctaa ggagctgtga ttcagaccca
     4801 gttctgtcag ctctagaggc accctgcatc atgcccacca gggtgatccc cctgggatgg
     4861 accatctcgg gatatgaggc ctcggaggct ggggttgaga tttggtcctg aagagcttat
     4921 agccagattg ccacattcaa gtgtaagtcc aggaaagggg caggcggcag tgcacaggga
     4981 tttatcagtt ccagaacctc acagtgataa gaggctttag agagcatcta atcgagacct
     5041 ttaatttttc ggggagagca gctgaggccg tgtggaaaat tagtggagag ctgacaagtg
     5101 tctgggctcc tggcccaggg gtccgtggtc cagcacgttg tgcgttcagt gggaagcaaa
     5161 gggcttgccc gggattacct gccccagccc cgaggtgggt tgtgctccct gcagctgcca
     5221 tcggcccgct ttgcttcgtc ctggcagatg cccagtgatt gtccccgagc aagtgccagg
     5281 gttgggctga gctgctatga cagggaggcc cagggagttc tgctcaggga gccaaaggga
     5341 acagccagat cctgaatgtt ctatgttcac ctgccccagc cccacccacc ctggcccact
     5401 ccacaggccc ctgaccatgg tcactcacgg agagggatgg aggagaaggt ggttgaactg
     5461 agtactgaga acccagagga cagagcccac agcttccaag caggaaaagg gacctctctg
     5521 aaaaatctgg ataaccagaa ttatcacagc accttctcat tcccagcgcg tccttctgag
     5581 ctcagacctt gagcatttac tgggtttctt tttgaggaag agggaaagtg acaaaggaca
     5641 aaacaatgca aatcttcatg actgaagacg atcaaagact ccctggagcg agaaaacagt
     5701 tactgccaga agcagaatgg aagagccaaa aagtacacaa aatggacgcc ataaattctg
     5761 aaataaaagt gtatgatgtg ttctgagtca ctgtagaagt catgcattta ttatcaagat
     5821 agaaaagagc agagaatgac gtggacattg gtcctcggag aggctgcgta ggtggtgcgg
     5881 tccccggggg attctggatg ctggtctttt gaccgtggcg gcagcctcgc gcctgcccgg
     5941 atggctccat ccagacattt ggcaaggctg tcatctgctc ttgggtcctt tttcaagctg
     6001 atttcctgcc tccccaagag gaggtttgag ccccattctg ccttggaaat aaatcctgac
     6061 agatgtgcac agcatatttg cagggaattt gcaggcctcg attattgggg gaatcagagc
     6121 ccattccaca ccgagcccca tccacgtggc tgagcaacac ccctgtgtcc cctgtatctg
     6181 tctcactggc tgtctttctc ccagtttctt aaagaaccac accattactg cgtttgccgt
     6241 tcgaagcgtt gtcccaacaa tgcagatggt tctgacaagg gctctatatg ctggcagaag
     6301 ggagcttcca accttttaac ttgaggaaaa tgaatctctg agaggcttga gagtgttgcc
     6361 aggtggagct tttcaggaga caggggtctt gagcccagga cacctaacta tcgagttttc
     6421 actaggagac ttagtggtgg ctttcatgag gccagtcgtt ctcaaggaag ggctgggggc
     6481 catcagcaat gtctggagac atttttgatt ctcacagctt ggtggggact gctattggta
     6541 tctcatgggt ggaggccagg gatgccaccg aacatcctac aatgcacagg gcagcccccc
     6601 acaaataaga attatccagc cccaaaatgc caatagtgcc gaggtcaggg gaccctgtgc
     6661 tggccatcct atctctgatt ctgaaactat gcatgctttc cacttttccc catttgtgag
     6721 tcattgagta aattaaagct cttctgagca gcagcagtga tcatggtcac tgccctgcgt
     6781 tcaaataatg cgagctgagg acagtgatct gcaactccca gcatgtcatg tggtctctta
     6841 gaaatccatg tgactgtttc caccatcttg ggcatttgtg gggaccccca gactggaggg
     6901 agaaagccct acaaagtgga tgggagtgtg gggctgaact tttccctacc cttaactttg
     6961 tgtctctggg acctccaggg acctggcccc tcaccaatgc atatgaagag tatgcttggg
     7021 gaagagctta ggaatggggt gggcatggga gtgctgggta gcagcctttg agcaaatctg
     7081 catcttctct tatttctgac ctttttccac gtgcccagtc ctatttctgc cagttgaagg
     7141 catactaata ttctttatac tatttaatct tttgcagaaa ccttactatt ataacttgct
     7201 actctccaga taccaattct tcatgccgag agcatcggaa atgtttttgt gtcttactga
     7261 tgttttcatg atcaacttgt aaatgtaagc agttgacttc ataaaaggta ttttaactat
     7321 tcttggagtc ctttgctacc caagcacctg gtttcaccat gcgatcactg acttctctac
     7381 agtgaagact ctttcttaat aaaggatttc gctgtgctct tttgattaaa aatatctaac
     7441 cttaaaagac gtaaaaatgt atctgtgaaa tctcactttg ttagcgttgc tgctgttgtc
     7501 attttctatt atgataactg aaaagagaaa agaagaaaac atgaactcct ctgtgtctgg
     7561 ttctcatctg tgctttatgc aaaggagatg atctactcag ctttaaatgg ctcagcccca
     7621 gcgtcac
//
