LOCUS       NM_017924               2914 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens chromosome 14 open reading frame 119 (C14orf119),
            mRNA.
ACCESSION   NM_017924
VERSION     NM_017924.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 2914)
  AUTHORS   Guo,X., Zhu,L., Zhao,X., Wu,X., Yang,J., Huang,J., Gu,L. and Su,L.
  TITLE     Influence of the rs6736 Polymorphism on Ischemic Stroke
            Susceptibility in Han Chinese Individuals via the Disruption of
            miR-7-1 Binding to the C14orf119 Gene
  JOURNAL   J Mol Neurosci 72 (3), 459-467 (2022)
   PUBMED   34510374
  REMARK    GeneRIF: Influence of the rs6736 Polymorphism on Ischemic Stroke
            Susceptibility in Han Chinese Individuals via the Disruption of
            miR-7-1 Binding to the C14orf119 Gene.
REFERENCE   3  (bases 1 to 2914)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA605680.1, BC061637.1, AL117258.4 and BC009645.1.
            
            On Nov 23, 2018 this sequence version replaced NM_017924.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.291503.1,
                                           SRR1660809.138986.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000319074.6/ ENSP00000322238.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                DA605680.1         32-65
            35-947              BC061637.1         1-913
            948-2609            AL117258.4         144930-146591       c
            2610-2914           BC009645.1         2536-2840
FEATURES             Location/Qualifiers
     source          1..2914
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..2914
                     /gene="C14orf119"
                     /note="chromosome 14 open reading frame 119"
                     /db_xref="GeneID:55017"
                     /db_xref="HGNC:HGNC:20270"
     exon            1..115
                     /gene="C14orf119"
                     /inference="alignment:Splign:2.1.0"
     exon            116..2914
                     /gene="C14orf119"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..539
                     /gene="C14orf119"
                     /note="My028 protein"
                     /codon_start=1
                     /product="uncharacterized protein C14orf119"
                     /protein_id="NP_060394.1"
                     /db_xref="CCDS:CCDS9588.1"
                     /db_xref="GeneID:55017"
                     /db_xref="HGNC:HGNC:20270"
                     /translation="MPLESSSSMPLSFPSLLPSVPHNTNPSPPLMSYITSQEMKCILH
                     WFANWSGPQRERFLEDLVAKAVPEKLQPLLDSLEQLSVSGADRPPSIFECQLHLWDQW
                     FRGWAEQERNEFVRQLEFSEPDFVAKFYQAVAATAGKD"
     regulatory      921..926
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C14orf119"
                     /note="hexamer: AATAAA"
     polyA_site      947
                     /gene="C14orf119"
                     /note="major polyA site"
     regulatory      1038..1043
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C14orf119"
                     /note="hexamer: AATAAA"
     polyA_site      1057
                     /gene="C14orf119"
     polyA_site      1106
                     /gene="C14orf119"
     regulatory      1552..1557
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C14orf119"
                     /note="hexamer: AATAAA"
     polyA_site      1581
                     /gene="C14orf119"
     regulatory      2895..2900
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C14orf119"
                     /note="hexamer: AATAAA"
     polyA_site      2914
                     /gene="C14orf119"
ORIGIN      
        1 gtgggctgcc gggctggccc agcttagggt tttcaggaaa tttggaagct gccgcagtag
       61 ttggagtcta aggactcgtg acaatcttcg ggtgcccttc gagagaaaag gggaggatgc
      121 cactggagtc atcctcttca atgccactat ccttcccatc tctcttaccc tcagtaccac
      181 acaatactaa cccttcccct cctctgatgt cttacatcac ctcccaggag atgaagtgta
      241 ttcttcactg gtttgccaat tggtcaggtc cccagcgtga acgtttccta gaggacctgg
      301 tagctaaggc agtgccagaa aaattacaac cactgctgga tagtctggag cagcttagtg
      361 tgtctggggc agaccgacca ccttctatct ttgagtgcca gctacatctt tgggatcagt
      421 ggtttcgagg ctgggctgag caggagcgca atgaatttgt cagacagctg gagttcagtg
      481 agccagactt cgtggcaaag ttttaccaag cagtggctgc tacagctggt aaggactgat
      541 aggcattcag accaaagaag ataaccatag ctgatggagc catgactctc tacaatgata
      601 actcaattca aatgtgtcgc ctaaagctct ggaactggta ttccaaccag ctgaccgaac
      661 tcactgacca gtacaggcat ggttatttca acattaatag catgtcaact ggactcctat
      721 ttgtaaatgt tatcaatcta agcaatccag ctcatcagtc tactagtttg cttctttccg
      781 agagatgtca agtcctcaag aatttgatgg cttcttctgc agctataacc acaaggaacc
      841 tacacattgt aactcaagtc cactgctggc tcatgaaatg tgtaaagtag aaccctcctt
      901 cccgagaaat aagacaggac aataaaaggt ggcgtttttg tactttacct ggattccatt
      961 ggctggtttt accactccta tcagattgta gtgtaattgt gtgatacgca aaccattagt
     1021 tttcccagtg atgatttaat aaaattatga aaaatcagga gagggagata attagttgct
     1081 tcctccttca cactgtttga atcgaactcg cggtgacttt tttttttttt taaaaacatg
     1141 ggttgtcact taagtttgga gtgcagtggc atgatcatca gtgagcgtga gatcactgta
     1201 acctcaaatt ctaggctgaa gtaatctttc tgcctcagtc tcctgagtat ctaggactac
     1261 aggcccgcac aacaatatct ggctaatttt taaattattc tgtagataca ggggtcatgc
     1321 tacgttttct agtctggtct tgaactgctg gcctcaagcg atccattctc accttggcct
     1381 cccaaagtgc tgggattaca ggcatgaacc atcatacctg gcctttttct aaggcatatg
     1441 tatgtgatat tcttggaact ggtagcaggt gttcctattc tgtaagtttg ctttacaaca
     1501 atacgaaaat aagtgacaat ttacaggttg aacaatttat ttttgtacca aaataaagaa
     1561 tggatcttta gaactgtaaa acttcaccct tttttcattg ccaggctata taatattgac
     1621 aaccggggaa agaggcattc caaagaaagt agaaattaag tatacacaat agattttcca
     1681 tccagttgtc tcacaagaaa ttattctctt ccttaccccc tgtcatgttc tgggcaacat
     1741 cacacctccc ttattcctct aactgggacc cttgtgctgt ggagctctgg tgaatggtaa
     1801 gaggcagatg gtctcacagg aagagtggct cttttctggt aggctgtggt tcccattaca
     1861 cccaccagga ttagcagcat taggcagagt cccatggaca gccttaggtg ggtcatggag
     1921 ggattatggt ctgaagtaac cagcaaccta ggaacataga aggtaatatt tggcatggaa
     1981 taatgcctag ccttagtaga taaagcggca ttaccttttt tttttttttt ttttggagac
     2041 aaggtcttgg tctgttgccc aggctggagt gcagtggtgt gatcttggct caccgtaatc
     2101 tccgcctccc aggctcaagc aattctcctg cctcaacctt ccgaatagct gggactacag
     2161 gcgcacgccg caccaccacg tctggctaag gggctttacc cttaaagata gagctcatga
     2221 agccccgcct catccaagca ttaagctaaa caggaaatca ttaagaggga ctatcgaacc
     2281 ttaaagtaga aataagatca agatctaagt cttctagcat cttatattat tggaagaaga
     2341 cctaacttgg cagcaaggga agtggcttaa gggaagagtc agtctatgtt ctttaggtag
     2401 ctagacacaa tccctaacag tgcttaagaa aggaaggggg ctgggagtgg tggcagtggc
     2461 tcccagcact ttgggaggca gaggccggtg ggttgcttta gctcaggagt tggagacaag
     2521 cctgggcaac atggtgaaac tgtctctatc aaaaatacaa aaattagctg gcatggtggt
     2581 gtgcacctgt agtcccagct acttgggaag ctgaggtggg ggaatcactt gagcctaggg
     2641 aggtcgaggc cacagtgagc tgagatcacc ccactgcatt ccagcctggg tgacagagcg
     2701 agaccctgtc tcaaaaaaga agaagaaaaa ggtgggggga ggggactaag atccctatgt
     2761 cctagagatg ggggaatgtg ttattgtatg ggaggaggga gtcaggtagt gacgggactg
     2821 gatgatcgtg ttagggatct ttgttctctg aaacgcaacc ctgtctagga caatatacac
     2881 gtgagtgagt gcttaataaa tttaatttca aaca
//
