LOCUS       NM_001389625            1443 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens chromosome 12 open reading frame 76 (C12orf76),
            transcript variant 4, mRNA.
ACCESSION   NM_001389625 NR_148516
VERSION     NM_001389625.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
REFERENCE   2  (bases 1 to 1443)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007546.6.
            
            On Jan 6, 2021 this sequence version replaced NR_148516.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC041968.1, DA686421.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000615315.2/ ENSP00000480634.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-160               AC007546.6         37836-37995         c
            161-1443            AC007546.6         30650-31932         c
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.11"
     gene            1..1443
                     /gene="C12orf76"
                     /note="chromosome 12 open reading frame 76"
                     /db_xref="GeneID:400073"
                     /db_xref="HGNC:HGNC:33790"
     exon            1..160
                     /gene="C12orf76"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..246
                     /gene="C12orf76"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 4; uncharacterized protein C12orf76"
                     /codon_start=1
                     /product="uncharacterized protein C12orf76 isoform 2
                     precursor"
                     /protein_id="NP_001376554.1"
                     /db_xref="CCDS:CCDS91748.1"
                     /db_xref="GeneID:400073"
                     /db_xref="HGNC:HGNC:33790"
                     /translation="MLRPALPWLYLGLCSLLVGEAEAPSPVDPLERSRPYAVLRGQNL
                     VLMGTIFSILLVTVILMAFCVYKPIRRR"
     exon            161..1443
                     /gene="C12orf76"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1421..1426
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C12orf76"
                     /note="hexamer: ATTAAA"
     polyA_site      1443
                     /gene="C12orf76"
                     /note="major polyA site"
ORIGIN      
        1 ctctctgctt ctgcagggct ggggaagatg ctgcgtccag cgttaccgtg gctgtacctt
       61 ggcctctgca gcctcctggt gggggaggca gaggccccga gccccgtgga tccgctggag
      121 cggagccggc cgtacgcggt gctgcgaggg cagaacctgg tgttgatggg aaccattttc
      181 agcatcctgc tggtgactgt catccttatg gcattttgtg tctacaagcc cattcggcgt
      241 cggtgacagc cagacaagtt cttcaatgag tatttgggaa taggataagt tgtgttgcac
      301 acaggccagt ggagaagttg gaaccaaaac tttcctactt ggaaatgacc tttggtctgg
      361 acagttggta aatgctaaat gaattagaag aaaacatgta ctagacatta ttttttccta
      421 acactgtagc gcaaataatt ggcccctgag tccgcttctc agtgtttctg actgtacttg
      481 ttaaaagtaa gacctgaaag ctccaaaggt cagtgtaaag atggagtgtt catgagaaag
      541 aaaacatggt aaccttgtga gtgcctgtaa gaaccacact gtaaagaact catcattaat
      601 gcttgaaaat gttattaaga aggagactta ccatgcagac attccctatt taagaaccat
      661 ttggttacag tgggttaaga atcacagatt ttttttttta atctcacctg agttagccta
      721 gaatgcgctg gttgcaaagt ggtgtcagct gtggggatct tgggccctcg ttcctcacct
      781 gcatcctgcc ctgcactcag gtgctccccc tgaagtcagg gtcacatcag gtagacctgt
      841 tactatatgc acctttggcc tggaatgctc tgaagttgga ctggaaatgt tactaggttg
      901 gcctgttaca aaaaggaccc catcctgctt aaacacattg atctcccttg ccctgcattt
      961 gagtctttct agcccacggt ctgaaacttg aggcagcttt ccagatttgg aatgtaaaag
     1021 gctcagtggg cactctgttc atccctgggt ggggagggcc cagccaacag aagtgcatgt
     1081 ccactgtgcg ggccagtgtg tgtttacaca aatttcatct cagctttgaa aatgctgcta
     1141 ttagtttcca ctgttggtga actggatttt ttcctcctat tgaaatgata ctttcatact
     1201 tataaagctg tcgtcaatat ttatttcaag gtgctagatt taattttgtt attaaattga
     1261 aatgcttatc ttgtgttcaa gcacagcact gattttaaca acctgcattt aatgtgaagt
     1321 aaccgaagta ggatactgta actgtgtaag gattttgttt gtaatcttgt aacattgaac
     1381 cattgaaatg ttcagttctt tgcttttgag caaaacgtca attaaaacta aagtaaaatc
     1441 cta
//
