LOCUS       NM_152319                904 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens chromosome 12 open reading frame 54 (C12orf54), mRNA.
ACCESSION   NM_152319
VERSION     NM_152319.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC089987.26, BQ429029.1, BC031670.2 and BF510008.1.
            
            On Jun 2, 2019 this sequence version replaced NM_152319.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.325922.1,
                                           SRR5189667.271011.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000548364.7/ ENSP00000447109.1
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 AC089987.26        129083-129087       c
            6-79                BQ429029.1         4-77
            80-764              BC031670.2         1-685
            765-894             BF510008.1         16-145              c
            895-904             AC089987.26        115061-115070       c
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.11"
     gene            1..904
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /note="chromosome 12 open reading frame 54"
                     /db_xref="GeneID:121273"
                     /db_xref="HGNC:HGNC:28553"
     exon            1..79
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            80..201
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..520
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /codon_start=1
                     /product="uncharacterized protein C12orf54"
                     /protein_id="NP_689532.1"
                     /db_xref="CCDS:CCDS8764.1"
                     /db_xref="GeneID:121273"
                     /db_xref="HGNC:HGNC:28553"
                     /translation="MAQHPCQDQEQKVEMTSKQQRSTSIEETMRPQEKQVTITETLWD
                     QVLTVFKDIQKELQEDARIRGMSNCSMTPMTSAPRTGSIRPPDSLMTPKLRRLQFSSG
                     EQPSGGRIHNLKTQLFSQSAYYPGP"
     exon            202..232
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            233..271
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            272..304
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            305..329
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            330..378
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            379..560
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            561..904
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      747..752
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /note="hexamer: AATAAA"
     polyA_site      766
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /note="major polyA site"
     regulatory      884..889
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
                     /note="hexamer: CATAAA"
     polyA_site      904
                     /gene="C12orf54"
                     /gene_synonym="HSD-29; HSD-30"
ORIGIN      
        1 gttgtgagat ggggctcaaa taggaaaaag tctaggggtg aaggagtggg gcaaagtgta
       61 atttggggaa ccaagcaggg gcctggagct atctccatct tcagctccag agtccttggt
      121 ttctgtctga gaacaaatgg cacagcatcc ctgccaggat caggaacaaa aggtagaaat
      181 gacctccaag cagcagagaa gcacatccat agaagagaca atgagaccac aggaaaaaca
      241 ggtaaccatc actgaaaccc tgtgggacca ggtgctgaca gtttttaagg atatacaaaa
      301 ggagctgcag gaagatgctc ggattcgagg gatgagcaac tgctccatga cacccatgac
      361 atcagcaccc aggactggaa gcataaggcc tccagattcc ttgatgaccc caaagttgag
      421 aagattgcag ttcagctctg gagagcagcc atcaggaggc cgtatccaca acctgaagac
      481 acagctcttc agtcaatcag cttactaccc tggaccctaa ctctacaatc aaggaagaag
      541 gacatctctg cttccgccag cacagcttca gttggggaag atattagcag acatcatcac
      601 tgaacccaga agagagggtg gtgcccatga gtggagatgc cagggtctat ggctgaaact
      661 gggaacttgg aaatcaagtg agacccaagc aaggaaacca actgccaaag caaggaaacc
      721 agcttggttt ggcaaacagc tgatgaaata aatgtgacgt agaagacttg ccttcctggt
      781 tcttcctggg ctgtggaatg ggtagtgata gaatttccaa gtatgatagt gcatttggtt
      841 caaagaacag cactgtagca tgggagaacc tgcactataa tgtcataaac tcaatctgac
      901 tttg
//
