LOCUS       NM_207645               5867 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens chromosome 11 open reading frame 87 (C11orf87), mRNA.
ACCESSION   NM_207645
VERSION     NM_207645.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5867)
  AUTHORS   Tran,M.T.M.T., Yeh,K.T., Chuang,Y.M., Hsu,P.Y., Low,J.T.,
            Kumari,H., Lee,Y.T., Chen,Y.C., Huang,W.H., Jin,H., Lin,S.H. and
            Chan,M.W.Y.
  TITLE     Methylomic analysis identifies C11orf87 as a novel epigenetic
            biomarker for GI cancers
  JOURNAL   PLoS One 16 (4), e0250499 (2021)
   PUBMED   33886682
  REMARK    GeneRIF: Methylomic analysis identifies C11orf87 as a novel
            epigenetic biomarker for GI cancers.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5867)
  AUTHORS   Niu,J., Zhang,B., Cui,K., Gao,Y., Li,Z. and Qian,Z.
  TITLE     Suppression of miR-147b contributed to H37Rv-infected macrophage
            viability and migration in tuberculosis in vitro
  JOURNAL   Microb Pathog 144, 104125 (2020)
   PUBMED   32179078
  REMARK    GeneRIF: Suppression of miR-147b contributed to H37Rv-infected
            macrophage viability and migration in tuberculosis in vitro.
REFERENCE   3  (bases 1 to 5867)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 5867)
  AUTHORS   Etemadikhah,M., Niazi,A., Wetterberg,L. and Feuk,L.
  TITLE     Transcriptome analysis of fibroblasts from schizophrenia patients
            reveals differential expression of schizophrenia-related genes
  JOURNAL   Sci Rep 10 (1), 630 (2020)
   PUBMED   31959813
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5867)
  CONSRTM   Schizophrenia Working Group of the Psychiatric Genomics Consortium
  TITLE     Biological insights from 108 schizophrenia-associated genetic loci
  JOURNAL   Nature 511 (7510), 421-427 (2014)
   PUBMED   25056061
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK303693.1, BC035798.1, DA232989.1, AB096240.1, AK091086.1 and
            DA221578.1.
            
            On May 17, 2019 this sequence version replaced NM_207645.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.229281.1,
                                           SRR1803613.285277.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144333, SAMEA2145743
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000327419.7/ ENSP00000331581.6
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AK303693.1         71-80
            11-2398             BC035798.1         1-2388
            2399-2682           DA232989.1         276-559
            2683-4100           AB096240.1         1861-3278
            4101-5812           AK091086.1         1266-2977
            5813-5867           DA221578.1         483-537
FEATURES             Location/Qualifiers
     source          1..5867
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q22.3"
     gene            1..5867
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /note="chromosome 11 open reading frame 87"
                     /db_xref="GeneID:399947"
                     /db_xref="HGNC:HGNC:33788"
     exon            1..74
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /inference="alignment:Splign:2.1.0"
     exon            75..5867
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /inference="alignment:Splign:2.1.0"
     CDS             334..927
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /note="uncharacterized protein C11orf87; neuronal integral
                     membrane protein 1"
                     /codon_start=1
                     /product="uncharacterized protein C11orf87 precursor"
                     /protein_id="NP_997528.2"
                     /db_xref="CCDS:CCDS31672.1"
                     /db_xref="GeneID:399947"
                     /db_xref="HGNC:HGNC:33788"
                     /translation="MSARAPKELRLALPPCLLNRTFASPNASGSGNTGARGPGAVGSG
                     TCITQVGQQLFQSFSSTLVLIVLVTLIFCLIVLSLSTFHIHKRRMKKRKMQRAQEEYE
                     RDHCSGSRGGGGLPRPGRQAPTHAKETRLERQPRDSPFCAPSNASSLSSSSPGLPCQG
                     PCAPPPPPPASSPQGAHAASSCLDTAGEGLLQTVVLS"
     regulatory      5375..5380
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /note="hexamer: AATAAA"
     polyA_site      5395
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /note="major polyA site"
     regulatory      5793..5798
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /note="hexamer: AATAAA"
     polyA_site      5814
                     /gene="C11orf87"
                     /gene_synonym="LOH11CR1A; NEURIM1"
                     /note="major polyA site"
ORIGIN      
        1 actccacgct ttctgcagcc gccactgcag ccgcgcggcg ggggctccct ccttgcagcc
       61 agccggcggt ccagcctggt gcctctgcaa aggaaagggg agcgtggaga cgtgttcgag
      121 gtggtatcgg cgaggatctc tcgggcgccg ctcactcctt ggtcgccttg cttgccagca
      181 gttgctccct tagtccttgg ctcgctcgca caccccctcc cgctacaggg agcagttttg
      241 ggtggcgtgg gctccgtcct cttcttggct ggtaggaacg gtgtgcccaa gaggggaagc
      301 ctagtgggcc tggcccctcc cagccccgcg ccaatgagtg ccagggcgcc gaaggagctg
      361 aggctggcgt tgccgccgtg tctcctcaac cggacctttg cttcccccaa cgccagcggc
      421 agcggcaaca cgggtgcccg cggcccaggc gcagtaggca gcggcacctg catcacgcag
      481 gtgggacagc agctcttcca gtccttctcc tccacgctgg tgctgattgt cctggttacc
      541 ctcatcttct gcctcatcgt gctgtccctc tccactttcc acatccacaa gcgtaggatg
      601 aagaagcgga agatgcagag ggctcaggag gaatatgagc gggatcactg cagcggcagc
      661 cgcggtggcg gggggctgcc ccgacctggc aggcaggccc caacccacgc aaaggaaacc
      721 cggctggaga ggcagccccg ggactctccc ttctgcgccc cttccaacgc ctcgtcgttg
      781 tcctcttcgt cccctggcct cccgtgccag ggtccctgtg ctcctccgcc tccaccgcca
      841 gcctccagtc cccaaggagc acacgcagct tcctcctgtt tggacacagc tggcgagggc
      901 cttttgcaaa cggtggtact gtcctgatcg tctagcccct ctcgttcccc gtcctcgttt
      961 ccagcatctt tgccaccctt gcttttttcc ttcttccttc cttttccatt ttcctctggc
     1021 ccctctttcc tcttcctggt ttccttacct gccctcccct tactcttgtt tctcctccgc
     1081 cgaggcactg tgcggtattt gtaaatattg ggcgaggaaa gtctcggaag aagaaataac
     1141 gctgataata atactttatt aatatttata gtaattatta taatactaat aacacaatcc
     1201 aagcgcatga caaatcacat aatttctaac tgtcaatgga ggatgcatct tcccattcca
     1261 ccccgcgctc ccctcaatta ggaggagaaa ccgcacaagc taccaaatat ataaaaggca
     1321 ttgattcccg gagcaaaggg aggggagggg gcccggtaat gtacatagct gtcaagttaa
     1381 gatttagttt ccttccttcc cctctgaccc ctaagctttc acttttcctt tagcttccct
     1441 ttcctcccca ttcccaccct cagccgggct caggcaatag tatattataa agaaaatgtc
     1501 tacattaagc accaggactg caagaggcca tagagaatag tccccggaaa gtgtttatga
     1561 caggtacccc tcgccagtcc gcccatttct caccctttgg ttaaccatta cattttccag
     1621 gacagagcat ttaatttact ttttaaaatg accctcgctg gccgagcata agtacgttaa
     1681 aatctttaaa tgagtttttt ttaaaaagct aacgctttca ttccctgccc cgcccccacc
     1741 cgtacacctt tgacttgtga cattttcagg atttacaaag gatctgggag ctgtccagcc
     1801 aggtctggtg ctgaagtcgc ctcaccgttc tgattacttc ctctagttgt gaaggcagag
     1861 gaggggctgt tttggaaagt gactattctg gcttttggtt gggttctttc ttctttttct
     1921 acaatcgagt tagcgtgtac tattggtttt cttattatta aacattgcat aagttacctt
     1981 ttttgtaaaa aaaaaaaagt attaggtgat gtgcagtact gaaagtgcag tatctaacca
     2041 actagaacgt ttgttttatt tttagaacaa gtgcaccttt gttatatatt tagtatattg
     2101 gtaccaaata cagaaaaaaa ctatagttct gtactatgtc ctccaaactg tatattattg
     2161 ttcttaattt ccagctgttg atataatggt taccactgga tgagaaattc agtggtgcag
     2221 acctggcttc tgctgtttcc agaagtgttc ttttgtacct tattctgtag tagactgtta
     2281 taaaaagatg acacacacgc tttatttttt cttttgcaaa taatagaaaa aacacaacca
     2341 cagaaacaaa caaataatgg atgtgcaaga atgccatcta ttaaaaacat ggttaatatt
     2401 taaacagtgc ctgtagttct ccctgcatgc agttaccacc tggaggcagt ggtgtgtgtg
     2461 cttgcttgta ctgtatgtgg ttggggatga gactggtggg gatgttgggc aatttggatg
     2521 ataagacatg cgaatttcaa gaaaagctag atccagtaat tacttatagg atacaaatgt
     2581 ttgcagcttg tttgtttagt tacaaatctg tgcctgcagc aaaagaaagg ctctctttct
     2641 cagtctgtcc taacttcact gaacatacaa aaatactgag aaaaaaagaa agtgagaaaa
     2701 taagataaat attttattat tttctaatgc cagacaaggc catctatgtt agaaatggaa
     2761 gtagtctata gttatttacc accttgtttc ctttggttga atgacagaag aagccagaag
     2821 catattacaa tattaattat atgcagtgac atctcttctt ggaaatcaag cctttgacag
     2881 ctattcaaat ttttggaaaa tgtatgaatg aaagtgatct gcaaaaagct ctaccaagag
     2941 agtccttact atcctgcagg gtgtaaggca acagtgcccc tatgagcatc cctctcccaa
     3001 gcaactcatt gttctaaatt gtctacttgg tccagacata tgtgctctta tccagaggaa
     3061 acattacctc taatattttt ggtcatctat taaattgccc aagctcagtt tgcatctttt
     3121 ataaaaataa tttaataaac ttaattttaa tcacccataa gataatcacc tttcctgaag
     3181 cacagaagat catcattgaa gcatgccatc ttgtaatatt aggaagacca ggtataatct
     3241 ttgggtacaa tatattaaac aatgaaccag tttttctcca gtgccttagt cacttcctag
     3301 taataggtaa aagagtgcat taactccctc aggccactag ggaatcctgt agtgcatcag
     3361 agttctacac tgtacatcag aatgactaag gcactgtgaa gaagaaagtc cattgatttt
     3421 tgtagcttac cctcatccag tggtagctct ttaatacctt attacagaat gacttttgga
     3481 cttgaaattt gaatagaatc agggtcccag aagggagctt catcatttcc aatgagctcc
     3541 aataagtgca tggatattac tttctttccc ttatttggtg cactttctac agcgaataat
     3601 ttcccatttt attaaagcaa taagatgttc tgttgtgagc agtgctggat aacgattcca
     3661 ttttcttggt gctgaagcta cgcatatgtt cttgccttat gaatcatagt atattcaagg
     3721 catgcaataa taatcccctt ccaaggagca gcctgtacac tctgtggggg taattatgaa
     3781 attgtcctac atcatttctc cccaaaggaa tgcaaggagc aagagaaata aaagcattat
     3841 gtatattgta aaacaaatga tctcaatacc tctcaacgtg ggcacacatc tgtaatacac
     3901 ttttattgtg caactttaaa tgtgtgtgcc tttctccatt aattgactgt agtttaatat
     3961 ttttaatagt gctctgtgta aagatgatgc agtttgtgag tcagatttca tactgagctt
     4021 aatatactca aaacctaagc ttccagtggt attacttgtg atttttttat gagatagaga
     4081 attacatgaa attctagtaa tccagtttcc acacaaaatt atttcaataa gcacatatcc
     4141 aagcaatttg tacagacctt gtttaaagca ctgcttctta tagggctcaa ttggcagtct
     4201 caggagcttg ggatgctacc aacagggcat ttaggttttc atttttatga aacaaaaggc
     4261 aatctggaaa tagctaaatt tattttaagg attttattca ctgatgtccc gtcaaactaa
     4321 atgcttcaaa cccctatagc tacagcttaa cttctgcact tgctattcag tattaataag
     4381 gtggcatgct tgattcttat tgtttttaaa aatgagaaaa tttggagaga gaatactatt
     4441 atgtcaacgg tacaagactc tgaatcttga agatgtagat ggatataata tttagacttt
     4501 atatacaccc atagatatgt atttatatat gcatacgttt tgtataaatt tacaattgac
     4561 tttttgtatt ctcttttctg tcattacaag aatgagatgg aaaccaaaat agttgttcca
     4621 tcctcttacc caaagaggat actgaaaagt ccggtatgtg catgcacttg tttctctggg
     4681 gtcaaatctg aatgactttc tctttaataa tgaaagggga gagtcctggt tagcttggaa
     4741 aattggtaat tagataagct tcctttccta ggttagtgac tcaaatgtag caatgataat
     4801 aaagttatga ccatatcaat gtggtctaaa tatctagatg gaaagcaaaa atatccagaa
     4861 gaggtttagg gccatctaga ccacaaacct ggaacctgga ttgtggtttg atttttttca
     4921 ttttcaacct atatgttgtg tagaaataca atttatatct gcatagctaa aggtaaagtg
     4981 aaaatatgac cattatctgt ttagtttgag aaatcatttt tggataatat ggataaatta
     5041 gctttaagaa acttctttga catctgactt ttccaccatt tctatctgta tcaattgtat
     5101 taattagata atggttaaat ttttattttt ttatcatgta gacatatgct ttcatgcttt
     5161 tctgtgggtg aaagttgaac aattgctagc tgatattatg tggaagttac aggttaaagt
     5221 agaaccagaa attttaatat aatctgatca ggttccttag tcccattccc atgtgaatct
     5281 gaactttgaa tttgaatctg aaaggcctac ttatttgggc cattttttgt tggaacttgt
     5341 gattgtaact cacagatgtt tcagttcata ttagaataaa ttgcccaatc tataagagag
     5401 tgtttaatca ttggaatgaa tgtaaatctg attctgattt ggttatttat ttgataacat
     5461 ttgagaaaca gctaatgtgg cttgacatca atacttatta atgtcttcaa cctaataata
     5521 caattggtgt catgtatgaa tgcttagctg acaataagaa tttaatcaac tttatttgga
     5581 gacaatgact tatcaaggag gtcctaccca tttgtggtag ggatatttcc cttacagttg
     5641 tgattacaag ggattgtttc tatagagaga tgaacagcaa caacagtgac aatgatgaca
     5701 acagaaaaac tgacttttga acttgagtat atccaataga tagaagaaaa aagatattag
     5761 aattcatgga aattttgttt tgcttttcta tcaataaaag agttttcttg ttaattggct
     5821 ttttggacac tatttccttg ccaatttaat gtacaatata ccaggat
//
