LOCUS       NM_001353554            1168 bp    mRNA    linear   PRI 09-JUN-2024
DEFINITION  Homo sapiens chromosome 11 open reading frame 86 (C11orf86),
            transcript variant 1, mRNA.
ACCESSION   NM_001353554
VERSION     NM_001353554.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1168)
  AUTHORS   Cheng,Y., Kang,X.Z., Cheng,T., Ye,Z.W., Tipoe,G.L., Yu,C.H.,
            Wong,C.M., Liu,B., Chan,C.P. and Jin,D.Y.
  TITLE     FACI Is a Novel CREB-H-Induced Protein That Inhibits Intestinal
            Lipid Absorption and Reverses Diet-Induced Obesity
  JOURNAL   Cell Mol Gastroenterol Hepatol 13 (5), 1365-1391 (2022)
   PUBMED   35093589
REFERENCE   2  (bases 1 to 1168)
  CONSRTM   Psychiatric GWAS Consortium Bipolar Disorder Working Group
  TITLE     Large-scale genome-wide association analysis of bipolar disorder
            identifies a new susceptibility locus near ODZ4
  JOURNAL   Nat Genet 43 (10), 977-983 (2011)
   PUBMED   21926972
  REMARK    Erratum:[Nat Genet. 2012 Sep;44(9):1072. Fullerton, Janice M
            [added]; Hyoun, Phil L [corrected to Lee, Phil H]; Meng, Fan Guo
            [corrected to Meng, Fan]]
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY168701.1, AK026328.1 and AP003176.2.
            
            On Jun 3, 2019 this sequence version replaced NM_001353554.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7346977.639910.1,
                                           SRR5189658.82492.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2142348
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000683896.1/ ENSP00000506734.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-388               HY168701.1         2-389
            389-800             AK026328.1         413-824
            801-801             AP003176.2         120742-120742
            802-1163            AK026328.1         826-1187
            1164-1168           AP003176.2         121105-121109
FEATURES             Location/Qualifiers
     source          1..1168
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.2"
     gene            1..1168
                     /gene="C11orf86"
                     /gene_synonym="FACI"
                     /note="chromosome 11 open reading frame 86"
                     /db_xref="GeneID:254439"
                     /db_xref="HGNC:HGNC:34442"
     exon            1..335
                     /gene="C11orf86"
                     /gene_synonym="FACI"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..410
                     /gene="C11orf86"
                     /gene_synonym="FACI"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C11orf86; fasting and CREB-H
                     induced"
                     /codon_start=1
                     /product="uncharacterized protein C11orf86 isoform 1"
                     /protein_id="NP_001340483.1"
                     /db_xref="CCDS:CCDS91512.1"
                     /db_xref="GeneID:254439"
                     /db_xref="HGNC:HGNC:34442"
                     /translation="MGTGLRSQSLREPRPSYGKLQEPWGRPQEGQLRRALSLRQGQEK
                     SRSQGLERGTEGPDATAQERVPGSLGDTEQLIQAQRRGSRWWLRRYQQQVRRRWESFV
                     AIFPSVTLSQPASP"
     exon            336..1168
                     /gene="C11orf86"
                     /gene_synonym="FACI"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1144..1149
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C11orf86"
                     /gene_synonym="FACI"
                     /note="hexamer: AATAAA"
     polyA_site      1168
                     /gene="C11orf86"
                     /gene_synonym="FACI"
                     /note="major polyA site"
ORIGIN      
        1 agagggccag tgtcttgctg aggggccgga gcagtcctgt gcctgcagcc tccggagcca
       61 tgggaacagg gctgcgaagt cagtccttgc gagagccccg accctcctat ggaaagctgc
      121 aggagccctg ggggaggccc caggagggcc aactccgcag ggcgctaagc ctcagacagg
      181 ggcaagagaa gtccaggtcc cagggcctcg agagaggcac agaagggcca gatgccactg
      241 cccaggagcg ggtgccgggg agcctggggg acacagagca gctgatccaa gcccagcgaa
      301 gaggcagccg gtggtggctg aggcggtacc aacagcaggt aagaagaagg tgggagagct
      361 ttgtcgccat cttccccagc gtgactctga gtcagccggc ctccccgtag cccacactgg
      421 gcaccatcag ctaaagatgc tggaagccat cgtggccccc ttgctgtgcc tggaccagcc
      481 caccgtgtct gctgacctac ctcttcacag ctctctggac tttggctggg tggccctagg
      541 aggcttctgc caccagctca ctggagtcgc cacgtggctg ccactcttag ctctggccct
      601 tccactccag cactagctct ctttgaagat cccagcaggg tcaaaaagaa gggggctcag
      661 ctgtctgccc tctgggcttg ggtaggggcc ttggactatg attctatgaa ggtttagaag
      721 aagcctgccc ggaatggggg ctgtggacgc tcctgcccca cacgaccagc tgtcaacttc
      781 caggacggag cttgatgaag ccagacccat ggccgagagg ctcacggacg ttgcctggtc
      841 actgggccat gacccaactg cccttcttgt cagttgctga tggtgggcca gggcgcaggt
      901 ctccctccca gatggtgagc cctctggggc aaggaccaca gctgggtggc cctcctggct
      961 gagcactctg tgctgaaaac ctttgaacct cacggtgtcc tgatgaagga agcagaggaa
     1021 gtcttcctcc ctgtgtgaca gagggggaaa ctgaggccca gagtggggaa gggatttctt
     1081 ggttttgaca tctccgaccc caccccaccc catccagtgt ccagcactgg agtcgaacac
     1141 agtaataaag atgctgagaa aaagtcaa
//
