LOCUS       NM_080659               1104 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens chromosome 11 open reading frame 52 (C11orf52), mRNA.
ACCESSION   NM_080659
VERSION     NM_080659.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1104)
  AUTHORS   Yang,Y., Hwang,H., Im,J.E., Lee,K., Bhoo,S.H., Yoo,J.S., Kim,Y.H.
            and Kim,J.Y.
  TITLE     Flashlight into the Function of Unannotated C11orf52 using Affinity
            Purification Mass Spectrometry
  JOURNAL   J Proteome Res 20 (12), 5340-5346 (2021)
   PUBMED   34739247
  REMARK    Erratum:[J Proteome Res. 2022 Feb 4;21(2):557. doi:
            10.1021/acs.jproteome.1c00932.. PMID: 35048698]
REFERENCE   2  (bases 1 to 1104)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1104)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ102454.1 and BC008501.1.
            
            On Nov 22, 2018 this sequence version replaced NM_080659.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC008501.1, SRR1803612.393028.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000278601.6/ ENSP00000278601.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               BQ102454.1         37-164
            129-1104            BC008501.1         129-1104
FEATURES             Location/Qualifiers
     source          1..1104
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q23.1"
     gene            1..1104
                     /gene="C11orf52"
                     /note="chromosome 11 open reading frame 52"
                     /db_xref="GeneID:91894"
                     /db_xref="HGNC:HGNC:30531"
     exon            1..92
                     /gene="C11orf52"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..432
                     /gene="C11orf52"
                     /codon_start=1
                     /product="uncharacterized protein C11orf52"
                     /protein_id="NP_542390.2"
                     /db_xref="CCDS:CCDS8353.1"
                     /db_xref="GeneID:91894"
                     /db_xref="HGNC:HGNC:30531"
                     /translation="MGNRVCCGGSWSCPSTFQKKKKTGSQTRRTLKPQPQQLQQNLPK
                     GHETTGHTYERVLQQQGSQERSPGLMSEDSNLHYADIQVCSRPHAREVKHVHLENATE
                     YATLRFPQATPRYDSKNGTLV"
     exon            93..130
                     /gene="C11orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            131..192
                     /gene="C11orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            193..1104
                     /gene="C11orf52"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1085..1090
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C11orf52"
                     /note="hexamer: AATAAA"
     polyA_site      1104
                     /gene="C11orf52"
                     /note="major polyA site"
ORIGIN      
        1 ggaaatgcac aagcctcttg atgcataaaa acagctgggc tcccttggag acagagcgcc
       61 atgggaaacc gggtctgctg cggaggaagc tggagctgcc catcaacttt ccagaagaaa
      121 aagaaaacag gaagccaaac aagacggaca ctgaagccgc agccacaaca gctgcagcag
      181 aatctcccaa agggccatga aacaacagga catacgtatg aacgggtgtt acagcagcaa
      241 gggtctcaag agaggagtcc aggcctcatg tcggaagaca gcaacttaca ttatgctgac
      301 attcaagtgt gcagccgtcc ccatgcccgg gaagtgaaac acgtgcattt agaaaacgct
      361 acagagtatg cgacccttcg cttcccccag gccacacctc gctatgacag caagaacggg
      421 accctggtgt gagcgcttgg gaggaaggcc cagtccatcg ttaaccacta cacctgtggg
      481 ggagaaccta ctgctttggg gaattgggtg gcaacccagg gatgttgtcc acgttttaag
      541 cttaaagaac tccaaagccc ctggaattgt gggcgtccca ttttctcccc tggcctctta
      601 cttgccactg ttaggttgga gttaatagtt ggtttagcta tgggtggata gctaaactta
      661 gctatccaca tgaggttagg tggagtgtgc agggaggtag gtcttcgacc ccaccattgt
      721 tgctcctgct cttgcaaagt gcagaaagag caggtaaaaa gttagcccat aagcacgtgg
      781 gctgatcttg ttggacttta attaatggta tcctttttca cacaccttaa actccaaagc
      841 tgaaggggag gtgctccgga aaagcattct gagcttttac attcagacac tagggctggc
      901 ttgggccatt tcctcagtgg ctgagtcagg ttccagacct taacagacaa atgggggaag
      961 ggggctgagg cgtggaggaa acgctttcag gacctcaagt cagtgataac cgacagcaca
     1021 gtgaggcctg gaaacttccc tcggagggac tgttggctct cgcaggtgcg gggccgctag
     1081 gatcaataaa cggcctgaga aaca
//
