LOCUS       NM_173525               1154 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens chromosome 11 open reading frame 42 (C11orf42), mRNA.
ACCESSION   NM_173525
VERSION     NM_173525.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Pineau,C., Hikmet,F., Zhang,C., Oksvold,P., Chen,S., Fagerberg,L.,
            Uhlen,M. and Lindskog,C.
  TITLE     Cell Type-Specific Expression of Testis Elevated Genes Based on
            Transcriptomics and Antibody-Based Proteomics
  JOURNAL   J Proteome Res 18 (12), 4215-4230 (2019)
   PUBMED   31429579
REFERENCE   2  (bases 1 to 1154)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC022762.8, BC031612.1 and AA781757.1.
            
            On May 17, 2019 this sequence version replaced NM_173525.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.64056.1, BC031612.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000316375.3/ ENSP00000321021.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AC022762.8         121792-121802
            12-782              BC031612.1         1-771
            783-783             AC022762.8         126736-126736
            784-1151            BC031612.1         773-1140
            1152-1154           AA781757.1         7-9                 c
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..1154
                     /gene="C11orf42"
                     /note="chromosome 11 open reading frame 42"
                     /db_xref="GeneID:160298"
                     /db_xref="HGNC:HGNC:28541"
     exon            1..131
                     /gene="C11orf42"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..1061
                     /gene="C11orf42"
                     /codon_start=1
                     /product="uncharacterized protein C11orf42"
                     /protein_id="NP_775796.2"
                     /db_xref="CCDS:CCDS7759.1"
                     /db_xref="GeneID:160298"
                     /db_xref="HGNC:HGNC:28541"
                     /translation="MLVGTPNLLTLDEADATWTLIKDKVIEEHFGPNAVAVPFLSDAA
                     CYDLLGVLVKQSRPAHTRLALPGRQGRRALKPVGPLPSLLEQAGSEGAFAHCTREYSP
                     NGRAERAYEETRMLDGQPCKIRLHMGDLRKKVAFLLLPPGQVSLQQTLPWLRSTHSIY
                     VIYQVFSCSWLQLGLTSTAREPQLLRLLRSLPVAFSCLKFSLQSKGVLGPQKPLTKDP
                     LPHGANWVRPNLSIMPPLAPTSAPADTTEAADVPPPVPAPPTPPPQEGPEDKPTRFSY
                     KGRNPFWRGPQILSENWLFSPRSPPPGAQGGGPRDPDGHSMSLPLLQGLSSEFDSDD"
     exon            132..930
                     /gene="C11orf42"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1154
                     /gene="C11orf42"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1124..1129
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C11orf42"
                     /note="hexamer: AATAAA"
     polyA_site      1154
                     /gene="C11orf42"
                     /note="major polyA site"
ORIGIN      
        1 gggctgcctg gggttcctgc agcagccact gccctgccca atccctccca taccccacca
       61 tgttggtggg tacccccaac ctgctgacac tggatgaagc tgatgccacc tggaccctca
      121 tcaaggataa ggtcatcgag gagcactttg ggcccaatgc agtagcagta cctttcctgt
      181 cagatgcagc ctgctatgac ctactgggtg tgctggtaaa acagtcccgc ccagcccata
      241 cccgcctggc tttgccaggt cggcagggcc ggagggcact gaaaccagtg gggccactac
      301 caagcctcct ggagcaggca ggatctgagg gtgccttcgc ccactgcact cgggaatact
      361 caccaaatgg ccgagcagag agagcctatg aagagacgcg aatgttggat ggacagccct
      421 gcaagatccg cctacatatg ggtgacctgc gcaagaaggt tgccttcctg ttgctgccac
      481 cagggcaggt gagcctacag cagactcttc cctggctccg aagcacccac agcatctatg
      541 tcatctacca ggtcttctct tgttcctggc tgcagctggg gctgacgtct acagcccgtg
      601 agccccagct cctccggcta cttcggtcat tacctgttgc cttctcctgc ctcaagtttt
      661 cactgcagtc taagggcgtg ctgggaccac agaagcctct cactaaagac ccattgcccc
      721 atggggccaa ctgggtcaga cccaacctca gcatcatgcc gcctctggcc cccacatcag
      781 cacctgctga tacaactgaa gctgctgatg tgcccccacc tgtcccagcc ccacctacgc
      841 cacctcccca ggaagggcca gaggacaaac ccaccagatt ctcctacaag ggccgaaacc
      901 ccttctggag ggggccccag atactgtcag agaactggct cttcagcccc cgcagccctc
      961 caccaggagc ccagggtggg ggccccaggg accccgacgg gcactccatg tccctgcccc
     1021 tgctgcaggg tctatcctca gagttcgaca gtgacgactg aagctgaagc aaaagattcc
     1081 gggggcaaag cccccaagat ctggcatagg ggtactggtc tctaataaac atcagctgct
     1141 gctcccccaa acca
//
