LOCUS       NM_020643               1866 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens chromosome 11 open reading frame 16 (C11orf16), mRNA.
ACCESSION   NM_020643
VERSION     NM_020643.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Amid,C., Bahr,A., Mujica,A., Sampson,N., Bikar,S.E.,
            Winterpacht,A., Zabel,B., Hankeln,T. and Schmidt,E.R.
  TITLE     Comparative genomic sequencing reveals a strikingly similar
            architecture of a conserved syntenic region on human chromosome
            11p15.3 (including gene ST5) and mouse chromosome 7
  JOURNAL   Cytogenet Cell Genet 93 (3-4), 284-290 (2001)
   PUBMED   11528127
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK074455.1, AC026894.7 and CA310676.1.
            
            On May 17, 2019 this sequence version replaced NM_020643.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK223377.1, AK074455.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144333
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000326053.10/ ENSP00000318999.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-430               AK074455.1         155-584
            431-571             AC026894.7         60894-61034
            572-692             AK074455.1         726-846
            693-1258            AC026894.7         61988-62553
            1259-1332           AK074455.1         1413-1486
            1333-1333           AC026894.7         66575-66575
            1334-1866           CA310676.1         18-550              c
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..1866
                     /gene="C11orf16"
                     /note="chromosome 11 open reading frame 16"
                     /db_xref="GeneID:56673"
                     /db_xref="HGNC:HGNC:1169"
     exon            1..47
                     /gene="C11orf16"
                     /inference="alignment:Splign:2.1.0"
     exon            48..232
                     /gene="C11orf16"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1469
                     /gene="C11orf16"
                     /codon_start=1
                     /product="uncharacterized protein C11orf16"
                     /protein_id="NP_065694.2"
                     /db_xref="CCDS:CCDS7794.1"
                     /db_xref="GeneID:56673"
                     /db_xref="HGNC:HGNC:1169"
                     /translation="MESSTGPRMPLLKYCSVATSLKAPGWDGAAPPWDLSFTYPFALQ
                     APWLTGHKPLARHASSCPCLHVADPAWQGPGWLGRAGDAANTWVLARREADGFYYRAQ
                     IKATPELERQGVLLVEFEAPLVAGPKLPAQQQRVVLEEDVIPLSPSVGYSLRPGDKVL
                     ALWEPGQQQYGPGTVLLGLEMRDPQRASKEKEITVHFWNGKAAKVPLGGVQSVSLTIW
                     KKAVERLHKSFTREHPRPLHWAPCCSLLGPITGRITNELPPDAPFLCPLCHHHACCQL
                     LCQGCLCGCPPCGTTWWPLTRTSEVMARELPELEPTAQLLPLEGPKEEKVAMHAPLAV
                     SSSSSSSCEQDGVENDLEMGPPQRLMVNSAVNTDPIFLEMPLRQSGLCQPEWRYWKRN
                     GPEPCLGKPGTRYSNICKEEKDHKQQRAQTAVVGTTKELVSKATHMKPPRTPPGEAEH
                     RKRSQSLAICQWNKNSR"
     exon            233..389
                     /gene="C11orf16"
                     /inference="alignment:Splign:2.1.0"
     exon            390..624
                     /gene="C11orf16"
                     /inference="alignment:Splign:2.1.0"
     exon            625..1269
                     /gene="C11orf16"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1491
                     /gene="C11orf16"
                     /inference="alignment:Splign:2.1.0"
     exon            1492..1866
                     /gene="C11orf16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1846..1851
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C11orf16"
                     /note="hexamer: AATAAA"
     polyA_site      1866
                     /gene="C11orf16"
                     /note="major polyA site"
ORIGIN      
        1 agaaggagcc tgaggctgag gtggaggctg ggagtttggg gctgtgggtg gatcctctga
       61 aggccatgga atcctccacg gggcccagga tgcctttgct caaatactgc agcgtggcca
      121 caagcctgaa ggcccctggc tgggacggtg ctgctccacc ttgggacctc tccttcacct
      181 acccctttgc cctccaagca ccctggctca ccgggcacaa gccccttgca aggcatgcct
      241 cttcttgccc atgtctccac gttgccgacc cagcatggca ggggcctggc tggctgggaa
      301 gagctggaga tgctgccaac acatgggtcc tagcaagaag ggaagcagat ggtttttact
      361 accgggccca aataaaggcc actcccgagc tggagagaca gggggtcctg cttgtggaat
      421 tcgaggctcc tcttgtcgca ggcccaaagc tgccagccca gcagcagaga gtggtcttag
      481 aagaggatgt cattcctctc tcaccatctg taggatactc actgagacca ggggataagg
      541 tgctggcact ctgggagcca ggccaacagc agtatggccc tggcactgtt cttttgggct
      601 tggagatgag agatccccag agagcatcaa aggaaaaaga aatcactgtt catttctgga
      661 atggcaaagc tgctaaagtg cccctaggtg gggtccagtc ggtgtccctg accatctgga
      721 agaaggctgt ggagaggctg cacaagtctt tcaccaggga gcaccccagg ccccttcact
      781 gggccccttg ctgctctctg ctagggccaa tcactgggcg catcactaat gagcttcctc
      841 cggatgctcc attcctgtgc cctctctgcc accatcatgc ctgctgccag ctactgtgcc
      901 agggctgcct ctgtggctgc ccgccatgtg gcacgacttg gtggcctcta accaggacct
      961 cagaagtcat ggccagagaa cttccagagt tggagcccac agcacagctt ttgcccctgg
     1021 aaggtcctaa agaggagaaa gtagcaatgc acgctcccct ggctgtttct tcctcctcat
     1081 cctcctcctg tgaacaagac ggtgtggaga atgatctgga gatgggccct ccccagagac
     1141 tgatggtgaa cagtgcagtc aacacagatc ccatctttct tgagatgcct ctgagacaga
     1201 gtggcctctg ccagcctgag tggaggtatt ggaagagaaa cgggcctgag ccatgccttg
     1261 ggaagccagg aacaagatat tccaacatct gcaaagaaga aaaggatcac aaacagcaga
     1321 gagcacaaac tgcagtagtg gggactacca aggagctggt ctcgaaagca acccacatga
     1381 agccaccgcg gaccccgcca ggggaagctg aacacagaaa gcggagtcag agccttgcaa
     1441 tatgtcagtg gaacaagaat tcccgttaga ctaagagccc tgaggatcta ggtaaagaat
     1501 aaacatggta aatattcgag gagagttata cagagtggct gacaaggcct tcttcaacgg
     1561 aaggaggcag aggacaggcc acaggtaaca gtcaaataac caccagtatc tccaccccac
     1621 gaagacctcc ctgcagataa gcagcaggaa ggcacctgtt gtgagggcta taggaatgtg
     1681 ggatcctgcc ctggggctcc ctgccagggc cctggtgaaa ctgctttaag atgcctcttc
     1741 cgtggaagag ggggtcagcc tgctttgggc aaatgtgtcc acagccactc tgccaccttc
     1801 ccataaagcc tagttgtaca tgagtgacat tttgtttcac ctcttaataa aaatgaattc
     1861 tcttca
//
