LOCUS       NM_001010912            1088 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens chromosome 10 open reading frame 120 (C10orf120),
            mRNA.
ACCESSION   NM_001010912 XM_374835
VERSION     NM_001010912.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   He,J., Su,L., Wang,W., Li,Y., Meng,L., Tan,C., Lin,G., Tan,Y.Q.,
            Zhang,Q. and Tu,C.
  TITLE     C9orf131 and C10orf120 are not essential for male fertility in
            humans or mice
  JOURNAL   Dev Biol 497, 11-17 (2023)
   PUBMED   36871790
  REMARK    GeneRIF: C9orf131 and C10orf120 are not essential for male
            fertility in humans or mice.
REFERENCE   2  (bases 1 to 1088)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1088)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL731543.9, BC065903.1 and AL704711.1.
            
            On May 17, 2019 this sequence version replaced NM_001010912.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.158582.1,
                                           SRR5189667.349682.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329446.5/ ENSP00000331012.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                AL731543.9         6524-6547           c
            25-1085             BC065903.1         5-1065
            1086-1088           AL704711.1         625-627
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.13"
     gene            1..1088
                     /gene="C10orf120"
                     /gene_synonym="bA318C4.1"
                     /note="chromosome 10 open reading frame 120"
                     /db_xref="GeneID:399814"
                     /db_xref="HGNC:HGNC:25707"
     exon            1..232
                     /gene="C10orf120"
                     /gene_synonym="bA318C4.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1064
                     /gene="C10orf120"
                     /gene_synonym="bA318C4.1"
                     /codon_start=1
                     /product="uncharacterized protein C10orf120"
                     /protein_id="NP_001010912.1"
                     /db_xref="CCDS:CCDS31302.1"
                     /db_xref="GeneID:399814"
                     /db_xref="HGNC:HGNC:25707"
                     /translation="MIREWKNDCQRIEKQRASDTMVQERKNEKPVRIFNTNSSFQDQA
                     PTCCQEDLSSASPLRIWSKFYRSDPRIALGKYSPLEKEILRLGGIHTIAARRLLAYKQ
                     EEECRMLKELQLLSPDYKQAMEYKKKHSSPCAICVPLEKIWTAKVIAPLEAFKMPQRE
                     QVNVSKHIERMRLARALGNHQPLPYIERFTRSSFLSGVGLGPMAKNKARRKEDNYDTH
                     NCDDANQDKKEEAEGKNTKRREIKMNVVFKSKEPKKCLTYHGNDRKSFLPAKKPERSI
                     AGLTNRNLFCISEFPGDLMLMNQDFISRRDHFSDLVKTYSLEEESIWKERMRKATPYH
                     Y"
     exon            233..308
                     /gene="C10orf120"
                     /gene_synonym="bA318C4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            309..1088
                     /gene="C10orf120"
                     /gene_synonym="bA318C4.1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1060..1065
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C10orf120"
                     /gene_synonym="bA318C4.1"
                     /note="hexamer: ATTAAA"
     polyA_site      1088
                     /gene="C10orf120"
                     /gene_synonym="bA318C4.1"
                     /note="major polyA site"
ORIGIN      
        1 gtcttagaaa caaactccag gtgtgaacac ctcccgtcct agcttattgc cggagtatga
       61 tcagagaatg gaagaatgac tgtcagagga ttgaaaaaca gagggctagt gacacaatgg
      121 tgcaagaaag gaagaatgaa aagccagtta gaatatttaa taccaactct tcctttcagg
      181 atcaagcccc aacgtgttgc caagaggatc tgagttctgc ttcaccgttg cggatatgga
      241 gcaaattcta cagatcagac ccacggattg cccttgggaa atactccccc ttggaaaaag
      301 agatcctacg tctaggtggc attcacacca tagcagcaag aaggcttttg gcttacaagc
      361 aagaggaaga atgcagaatg ctcaaggaac tacagttgct gtctccggac tacaaacaag
      421 caatggagta taaaaagaaa cattcctctc cttgtgctat ttgtgtaccc ctagaaaaaa
      481 tatggacagc aaaggtgatt gcgcccctgg aggcatttaa aatgccacaa cgagagcagg
      541 tgaacgtcag taagcacata gagaggatga ggcttgctcg ggctctggga aatcatcagc
      601 ctttacccta cattgaaagg tttacacgct cctcatttct gtctggggtg ggcctgggtc
      661 caatggcaaa aaataaggcc agacgaaagg aagacaacta tgacacccat aattgtgatg
      721 atgccaacca agataagaaa gaggaggcag agggaaaaaa cacaaaaaga cgagaaataa
      781 aaatgaatgt agttttcaag tcaaaagaac caaaaaaatg tttaacatac catggaaatg
      841 atcgcaaatc attcctcccc gcaaagaaac cggaacggtc catcgcaggc ctaacaaacc
      901 gaaatctttt ctgcatatca gaattccctg gtgacttaat gctaatgaat caggatttta
      961 tatcacggag agaccacttc agtgatctgg tcaagaccta cagcctggaa gaagagagta
     1021 tctggaaaga gcgcatgcgt aaagcaactc cttatcatta ttaaagtttt atttgttgcc
     1081 cagggtaa
//
