LOCUS       NM_001168390            4765 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens chromosome 10 open reading frame 105 (C10orf105),
            transcript variant 2, mRNA.
ACCESSION   NM_001168390 XM_001716040 XM_001723289
VERSION     NM_001168390.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4765)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL731541.6 and AK074172.1.
            
            On May 31, 2019 this sequence version replaced NM_001168390.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK074172.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AL731541.6         82596-82621         c
            27-287              AK074172.1         1-261
            288-4765            AL731541.6         56472-60949         c
FEATURES             Location/Qualifiers
     source          1..4765
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q22.1"
     gene            1..4765
                     /gene="C10orf105"
                     /note="chromosome 10 open reading frame 105"
                     /db_xref="GeneID:414152"
                     /db_xref="HGNC:HGNC:20304"
     exon            1..123
                     /gene="C10orf105"
                     /inference="alignment:Splign:2.1.0"
     exon            124..4765
                     /gene="C10orf105"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..530
                     /gene="C10orf105"
                     /codon_start=1
                     /product="uncharacterized protein C10orf105"
                     /protein_id="NP_001161862.1"
                     /db_xref="CCDS:CCDS44430.1"
                     /db_xref="GeneID:414152"
                     /db_xref="HGNC:HGNC:20304"
                     /translation="MSTEGPSLASSPAISPLAFLSAPVTPGTLAEATDPLPMLIALAC
                     IFLLLATCLLFMTLCKPAALDPSRRRAHECMPHHPGSPSEPQLRLWKRLGSLRLSLHS
                     FRHGRPTVPRQPLPGPEDNRSHCDYMESTKM"
     regulatory      4737..4742
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C10orf105"
                     /note="hexamer: AATAAA"
     polyA_site      4765
                     /gene="C10orf105"
                     /note="major polyA site"
ORIGIN      
        1 aagagcatat tgttttgtgt ctgtggctcg ggcttcttgt ggagaggcag gagagtgaag
       61 gcctgccgcg ggtgaggcct ccagtccacg gacggccaca ggccactgcg gctggaatca
      121 caggagccat gagcacagag ggccccagcc tcgccagctc cccagccatc agccccctcg
      181 cctttctctc agctcccgtc actcccggga cccttgcaga ggcaactgac cccctcccca
      241 tgctcatcgc cctggcctgc atcttcctcc tgctggccac ctgtctgctg ttcatgacgc
      301 tctgcaagcc ggccgcgctg gacccgagcc gccgcagggc tcacgagtgc atgccccacc
      361 accctgggag ccccagtgag ccccagctcc ggctctggaa gcgcctgggc tccttgcgcc
      421 tctccctgca cagcttccgc catggccggc ccaccgtccc tcgacagccc ctgccgggcc
      481 ccgaggacaa ccgcagccac tgtgactaca tggaatctac caagatgtaa tggggtgtcc
      541 acaaacatgc ccccacatcc ccctaggtct acctgtagat cctcctgctt cagagaccgg
      601 tgctgcaggc tgcaggaaga cagtggccca agcagtctgg gacacacact caccccccga
      661 agctccttgc atgcccaggc cagcgccctt tcccaaagat gatcctcaga agagcacctt
      721 cctctctgca gaccccctcg ctgctgcttg atgaaagact tctggtcaag agatgtgcac
      781 tcgtggtcat ctgggccttt ggcctgaggc tccacagggt acaacctggg gctcgtaacc
      841 acctcctaga agcagcaccc tcgctcgcca cagaagcctt gccctccagg tgccaaagcc
      901 cagcatggag aagttgccaa atggcaaagg ttccctttag tcaagtgaaa tgctcagcct
      961 acaccggggc caagacactg tcctggcatc tgtgctggcc cagtgctggg gcaaaacctc
     1021 ggggctctct tccttgggtt tcccgggtgc tgccagcatc tgcctggtgc cctgtgggag
     1081 cagctgcctc cctcctggtg gaacagatgc ctgggtgcca gctgggagga ggagcaaaca
     1141 gggctctcca agcatggtct tggcagccgt cttggtggcc cctcttcagg gcacccacgt
     1201 tgggatcaat caggaaggga ttgaagatga tcgaggaggc tcccttcaga ggccagggcg
     1261 ggtgctgtga cagagtggca agaggcaggg catttccagc agctggaggt gatgccacct
     1321 ggactcggag gaggacagct cacagcagct ccacacctca cccagggaaa gcggcagcct
     1381 ccccgagggt gggatggtct ggacctctcc aggacagctg tggggtccca agtcctgccc
     1441 acactaggga tgctatctgt ggttttggtg agtgctttgc tgatgacccg tcaaagcagt
     1501 cccaccccag gatgggcttc tcagaatccc aaacccttga cctctcctca caacgcgagg
     1561 gttaaacact ttggtcaggt cccaaatttg aagggtgggc agagggagga cctgggctgc
     1621 ccagctcctg tcccagtcag ctggccagga tcccaccaca aagctgcccc acccccatcc
     1681 tgctgtgacc cacagtgcag ccagccacgt ctccccaagg agtgagctct ggcttgccac
     1741 tccccagctc caaaaccttc actggctccc taatgccaaa tggatatagc caaagctcct
     1801 cagcgcagtg tgcagtgccc tctgggagct ggctccaatt aatctttcta gcctcatctt
     1861 gatccaaaac tccaggaaaa ctgaaagacc tgtcacccac taactgtggc ttatgcttca
     1921 cacacaccca ctctgtgaag ccctcctgcc tggagccgcc cctactgtct cctacctctc
     1981 ttggggagga aaaggaacat tctcttggca gcatgggtcc tttttgtcta tgtcttctct
     2041 ttcctaccag cttgggagct tgcagagagc cagacattgt ccagcccctc actttgactc
     2101 cccagttctg tgcacagaag tatgaggctt ctgtgtacag agtgaagcgt ggcccagcct
     2161 gggtgtgtcc ccaccctctg aggcaggagt cttggtggaa gctggcataa cacagagcct
     2221 catcttccct cagatgactc tagaaagatt tctctccaag caggctctat tggagaagcc
     2281 cactgtccct tccttccaag tcaatctgat ctcaaaaagt gagtccggct tcacaagaaa
     2341 cttaccaaga ggaccttgga gaagtcatcc tgagacgctg catttctccc tgagaaatgg
     2401 gagaactcag ggctgcccta tattaactcg ctggctctag gatttcagta agagtagtat
     2461 tgtgtaaata gaaaccaagt ctttgggttt agaaagtggg gcaggcctcc tccctaaggg
     2521 ttttgttcct tcctcccttc ctgctcagta acctcttcct ggtttgcttc ccctggggcc
     2581 tccctgcaaa tcctaggctg gattcagcct gtagccatcc acctcaccag caggccctgc
     2641 tggccactag gcactgtctt cctggaggtt ggggtggggg ttgaggctgc cctgaggcct
     2701 gaagaaggaa aagtccagga gggggagggc tctcaattgg gtttcaggca ccaggccagg
     2761 ggggtatgct ccaagtcctc acaagctgag gccctgatcg agagaaccct ctacttcctc
     2821 cttctggagc tagccaccac actctcgcaa atcctcaggg ctttctgggc tctctgtgtt
     2881 tctgggagtc agctccctgc tccccagccc tttcctgccc gcctcctggt cccgatgcag
     2941 ggaggggagc attgccagcc tcccacgctt ctgtccctcc caagcccggg agcctgcccc
     3001 agtgggcagg cccagattcc ctgtttggct cagcctccga gtcggaaacc ccatagttgg
     3061 taaagagact cattcactcc gggcctccct ccccacccag caactgaggc ctctgggcag
     3121 aggtgtgggt gcacacccaa attgttttca gggtcctccc ttctctccct ctgagccttg
     3181 gagctgttgc gcctgctccc tgggcaaagg agccctttct tcttgtgcct gtttacttcc
     3241 caagagggga gcctcggcca agggctctgt gaaagcagct ctgttctggg ccttgctggg
     3301 ccctggctct cttctcaact cctttccggg aaattgtgac gtctctttct ccccgctact
     3361 ctgaaaggcc cttctgggtg gggcgggaga tatgcagggg gaggccaagt cttcctcctg
     3421 tttgtgggga gccagagccc tatcctcagc tctgcaacct gggggcccac actccctggg
     3481 atgggagagg gcctgggtcc ccctttcccc acagcacctt ccagagcagc ggacccaccc
     3541 tgggccccca cctgcttccg cctctggtgc cactgagcat gtgccctcag ggccgtgtgt
     3601 ggctccgcct cccccagccc accacctgcc ccagaggcca cgggccacct gcctgcaaga
     3661 tgctgtggcc ttcagggatg tcctcaggga cgctggcctc atagctgctc tgcagaaaga
     3721 tgggccggtt gtcattcaca tccaggacag tgacgaacac ggtggctgtg cccgtgtgtc
     3781 gcttccctac agggccgttg tctgtgggag ttgaaggaag acaggtgtta gcagctgcct
     3841 gagagagggg cacacttcct gtgactttgc acactcccgg gcaccggcca gagaggtgcc
     3901 ctgttccgcc ccatctgccc tagcctttgc aaggggtgac ttccttttta gcttaggaat
     3961 aacactaaca gtatcaaata cttagataac accatgtgcc agccattctt ctaacccatt
     4021 cagtcctcac agcaacccca tgaagcagac actttactgt catccccatt ttacagagga
     4081 ggtaactgag gcactcaagt ggattgaatg atggctccca aaaaaaacag acccatgtta
     4141 aacccctggg aacctgtgaa gattaattta tttgggaaaa gggcctttga aaatgtaatt
     4201 acgttaagga tcttgagaag tgatcatcct gggtgagctg ggtggcccat aaacccaatg
     4261 gcaagtgtcc ttacaagaga aaggcagagg gacatttgag acagagagga ggaggccaca
     4321 tgcagatgga ggcagaggct ggagttatgc tgccacaagc caccgaatgc ctagcgactc
     4381 cagaaactgg gacggtcaag gactgattct ctctagagcc tttggaggaa gcgtgaccct
     4441 gccgacacct taatttctaa cttctggcct tgagaaccag gagagaatac acttctgctg
     4501 ttttaagttt gtggtagttt gtcgtggcaa atttaggatg cagatacagg tactaagagc
     4561 aaaaagccaa ctgctgtcag ggactggcgg gtatagcacc tgggtcaaac acctggatgg
     4621 gccccgctgg aagggcagct gtcctccact ccagtccaca gcggacaggc agaatgtggg
     4681 cccagagaca ccagatcttc tgatttctca tgagaaattg aacatctgag cttttaaata
     4741 aaatctcctg atctttaaac tttca
//
