LOCUS       NM_001207067            6511 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens basic leucine zipper and W2 domains 1 (BZW1),
            transcript variant 1, mRNA.
ACCESSION   NM_001207067
VERSION     NM_001207067.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6511)
  AUTHORS   Zhang,W., Zhang,N., Yang,Z., Zhang,X., Sun,A., Wang,L., Song,X.,
            Geng,Z., Li,J. and Hu,J.
  TITLE     [Overexpression of BZW1 promotes invasion and metastasis of gastric
            cancer cells by regulating Wnt/beta-catenin signaling and promoting
            epithelial-mesenchymal transition]
  JOURNAL   Nan Fang Yi Ke Da Xue Xue Bao 44 (2), 354-362 (2024)
   PUBMED   38501421
  REMARK    GeneRIF: [Overexpression of BZW1 promotes invasion and metastasis
            of gastric cancer cells by regulating Wnt/beta-catenin signaling
            and promoting epithelial-mesenchymal transition].
REFERENCE   2  (bases 1 to 6511)
  AUTHORS   Luo,A., Qiao,N., Hu,K., Xu,H., Xie,M., Jiang,Y. and Hu,J.
  TITLE     BZW1 is a prognostic and immunological biomarker in pancreatic
            adenocarcinoma
  JOURNAL   Medicine (Baltimore) 103 (5), e37092 (2024)
   PUBMED   38306570
  REMARK    GeneRIF: BZW1 is a prognostic and immunological biomarker in
            pancreatic adenocarcinoma.
REFERENCE   3  (bases 1 to 6511)
  AUTHORS   Qi,H., Zheng,Z. and Liu,Q.
  TITLE     Activation of BZW1 by CEBPB in macrophages promotes eIF2alpha
            phosphorylation-mediated metabolic reprogramming and endoplasmic
            reticulum stress in MRL/lpr lupus-prone mice
  JOURNAL   Cell Mol Biol Lett 28 (1), 79 (2023)
   PUBMED   37828427
  REMARK    GeneRIF: Activation of BZW1 by CEBPB in macrophages promotes
            eIF2alpha phosphorylation-mediated metabolic reprogramming and
            endoplasmic reticulum stress in MRL/lpr lupus-prone mice.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6511)
  AUTHORS   Li,Z., Ge,Y., Dong,J., Wang,H., Zhao,T., Wang,X., Liu,J., Gao,S.,
            Shi,L., Yang,S., Huang,C. and Hao,J.
  TITLE     BZW1 Facilitates Glycolysis and Promotes Tumor Growth in Pancreatic
            Ductal Adenocarcinoma Through Potentiating eIF2alpha
            Phosphorylation
  JOURNAL   Gastroenterology 162 (4), 1256-1271 (2022)
   PUBMED   34951995
  REMARK    GeneRIF: BZW1 Facilitates Glycolysis and Promotes Tumor Growth in
            Pancreatic Ductal Adenocarcinoma Through Potentiating eIF2alpha
            Phosphorylation.
REFERENCE   5  (bases 1 to 6511)
  AUTHORS   Singh,C.R., Glineburg,M.R., Moore,C., Tani,N., Jaiswal,R., Zou,Y.,
            Aube,E., Gillaspie,S., Thornton,M., Cecil,A., Hilgers,M.,
            Takasu,A., Asano,I., Asano,M., Escalante,C.R., Nakamura,A.,
            Todd,P.K. and Asano,K.
  TITLE     Human oncoprotein 5MP suppresses general and repeat-associated
            non-AUG translation via eIF3 by a common mechanism
  JOURNAL   Cell Rep 36 (2), 109376 (2021)
   PUBMED   34260931
REFERENCE   6  (bases 1 to 6511)
  AUTHORS   Li,S., Chai,Z., Li,Y., Liu,D., Bai,Z., Li,Y., Li,Y. and Situ,Z.
  TITLE     BZW1, a novel proliferation regulator that promotes growth of
            salivary muocepodermoid carcinoma
  JOURNAL   Cancer Lett 284 (1), 86-94 (2009)
   PUBMED   19446954
  REMARK    GeneRIF: BZW1 is a novel factor, promoting the growth of MEC cells
REFERENCE   7  (bases 1 to 6511)
  AUTHORS   Beausoleil,S.A., Villen,J., Gerber,S.A., Rush,J. and Gygi,S.P.
  TITLE     A probability-based approach for high-throughput protein
            phosphorylation analysis and site localization
  JOURNAL   Nat Biotechnol 24 (10), 1285-1292 (2006)
   PUBMED   16964243
REFERENCE   8  (bases 1 to 6511)
  AUTHORS   Mitra,P., Vaughan,P.S., Stein,J.L., Stein,G.S. and van Wijnen,A.J.
  TITLE     Purification and functional analysis of a novel
            leucine-zipper/nucleotide-fold protein, BZAP45, stimulating cell
            cycle regulated histone H4 gene transcription
  JOURNAL   Biochemistry 40 (35), 10693-10699 (2001)
   PUBMED   11524015
  REMARK    GeneRIF: Stimulates cell cycle regulation of histone H4 gene
            transcription.
REFERENCE   9  (bases 1 to 6511)
  AUTHORS   Machado,R.D., Pauciulo,M.W., Fretwell,N., Veal,C., Thomson,J.R.,
            Vilarino Guell,C., Aldred,M., Brannon,C.A., Trembath,R.C. and
            Nichols,W.C.
  TITLE     A physical and transcript map based upon refinement of the critical
            interval for PPH1, a gene for familial primary pulmonary
            hypertension. The International PPH Consortium
  JOURNAL   Genomics 68 (2), 220-228 (2000)
   PUBMED   10964520
REFERENCE   10 (bases 1 to 6511)
  AUTHORS   Hoja,M.R., Wahlestedt,C. and Hoog,C.
  TITLE     A visual intracellular classification strategy for uncharacterized
            human proteins
  JOURNAL   Exp Cell Res 259 (1), 239-246 (2000)
   PUBMED   10942595
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL833518.1, AB074176.1, AC007163.3 and AC005037.2.
            
            On Nov 22, 2018 this sequence version replaced NM_001207067.1.
            
            Transcript Variant: This variant (1) represents the predominant
            transcript and encodes isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.180610.1,
                                           SRR1660803.196126.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000409600.6/ ENSP00000386474.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1690              AL833518.1         321-2010
            1691-1701           AB074176.1         456-466
            1702-3019           AL833518.1         2022-3339
            3020-3150           AC007163.3         201-331             c
            3151-6511           AC005037.2         187148-190508       c
FEATURES             Location/Qualifiers
     source          1..6511
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q33.1"
     gene            1..6511
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /note="basic leucine zipper and W2 domains 1"
                     /db_xref="GeneID:9689"
                     /db_xref="HGNC:HGNC:18380"
                     /db_xref="MIM:619252"
     exon            1..81
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            82..155
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..1351
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /note="isoform 1 is encoded by transcript variant 1; basic
                     leucine-zipper protein BZAP45; basic leucine zipper and W2
                     domain-containing protein 1; putative protein product of
                     Nbla10236; eIF5-mimic protein 2"
                     /codon_start=1
                     /product="eIF5-mimic protein 2 isoform 1"
                     /protein_id="NP_001193996.1"
                     /db_xref="CCDS:CCDS56156.1"
                     /db_xref="GeneID:9689"
                     /db_xref="HGNC:HGNC:18380"
                     /db_xref="MIM:619252"
                     /translation="MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETG
                     TDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQE
                     DLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLAN
                     GTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMEL
                     FPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIIL
                     YVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQ
                     GQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSV
                     FLEQMKKFVEWLKNAEEESESEAEEGD"
     exon            156..332
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            333..427
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            428..493
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            494..629
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            630..739
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            740..910
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1057
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1196
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1319
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..6511
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2804..2809
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /note="hexamer: AATAAA"
     polyA_site      2831
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /note="major polyA site"
     regulatory      2988..2993
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /note="hexamer: AATAAA"
     polyA_site      3019
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /note="major polyA site"
     polyA_site      3194
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
     regulatory      6473..6478
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
                     /note="hexamer: AATAAA"
     polyA_site      6511
                     /gene="BZW1"
                     /gene_synonym="5MP2; BZAP45; Nbla10236"
ORIGIN      
        1 agttccggtc gcagaggaga caccgccgca gttgccggta catcggggat ttctggctct
       61 ttcctcttcg ccttaaattc gggtgtcttt tatgaataat caaaagcagc aaaagccaac
      121 gctatcaggc cagcgtttta aaactagaaa aagagatgaa aaagagaggt ttgaccctac
      181 tcagtttcaa gactgtatta ttcaaggctt aactgaaacc ggtactgatt tggaagcagt
      241 agctaagttt cttgatgctt ctggagcaaa acttgattac cgtcgatatg cagaaacact
      301 ctttgacatt ctggtggctg gtggaatgct ggccccaggt ggtacactgg cagatgacat
      361 gatgcgtaca gatgtctgcg tgtttgcagc ccaagaagat ctagagacca tgcaagcatt
      421 tgctcaggtt tttaacaagt taatcaggcg ctacaaatac ctggagaaag gttttgaaga
      481 tgaagtaaaa aagctgctgc tgttcttgaa gggtttttca gagtcggaga ggaacaagct
      541 agctatgttg actggtgttc ttctggctaa tggaacactt aatgcatcca ttcttaatag
      601 cctttataat gaaaatttgg ttaaagaagg agtttcagca gcttttgctg tgaagctctt
      661 taaatcatgg ataaatgaaa aagatatcaa tgcagtagct gcaagtcttc ggaaagtcag
      721 catggataac agactgatgg aactctttcc tgccaataag caaagtgttg aacacttcac
      781 aaaatatttt actgaggcag gcttgaaaga gctttcagaa tatgttcgga atcagcaaac
      841 catcggagct cgtaaggagc tccagaaaga acttcaagaa cagatgtccc gtggtgatcc
      901 atttaaggat ataattttat atgtcaagga ggagatgaaa aaaaacaaca tcccagagcc
      961 agttgtcatc ggaatagtct ggtcaagtgt aatgagcact gtggaatgga acaaaaaaga
     1021 ggagcttgta gcagagcaag ccatcaagca cttgaagcaa tacagccctc tacttgctgc
     1081 ctttactact caaggtcagt ctgagctgac tctgttactg aagattcagg agtattgcta
     1141 tgacaacatt catttcatga aagccttcca gaaaatagtg gtgctttttt ataaagctga
     1201 agtcctgagc gaggagccca ttttgaagtg gtataaagat gcacatgttg caaaggggaa
     1261 gagtgttttc cttgagcaaa tgaaaaagtt tgtagaatgg ctcaaaaatg ctgaagaaga
     1321 atctgaatct gaagctgaag aaggtgactg aattttgaaa ctacaccctc agtaaagcaa
     1381 acaggagttg tagataaaat gtcatgtctc atgtgtcctg gttcttacat cttcctacct
     1441 ccctgtatca agcatgatat aagggctttc atggcaaatt ttattttaac tgtttctatg
     1501 gttgctggaa atgttgggtt tagtttctaa aaccatgttt taagtagcta caggagctat
     1561 agatttgaat ctaatgttgc attagtcttt tcagttatct tctacctcct gtattttcta
     1621 ctgtaataat gtaatttaag gccttccaca atgaacagtt cactttattc cctgggtttt
     1681 ctataaacag ttttaaggat atgatttggt taaaaaataa tttgttataa aaattctgtt
     1741 tgcaaattaa actggaaaag tatccagagt ctcaaaaggc aatgatttgt gagataatat
     1801 ggcatgcccg gagccctgct catcaatgaa aaacccatat gtaataatcg aattcattta
     1861 acatgaatct tgagtacgtg gaccattgct tgcatgttaa ctttttgttt tgttttgttt
     1921 tgttttgttt tgcattttta actccagata tcctaaagct caattgtttg gtctctggtt
     1981 ttcatcctta gagaagccat ggagaacaga cttgaaaagt ttaggaaatc ataatgtggc
     2041 agaggtggtg ggaagaagaa agttgagctt tttccccttg agaaacttct gcatttagtt
     2101 tctatctttc caggcaaaac aaatgggtat tcttttcata caaccatttt caaatgaacc
     2161 ttagaaaagt cttaacattt aaggtatttt atgcacagaa tacacttaga ttgataggaa
     2221 agaactcgta atggagtttg agtaaagaaa atgactgatg tactaaaccc agtaaaaatt
     2281 gttgaaaatg ttaaaggtca gcatgttcta attgggaatc tagatatagc ttagatttcc
     2341 tattggctta gagtatttgc tataacaaat gaagtgcaat gacaattata tattcctact
     2401 cggtcatact ggactggctt cgttctctta atatactcag taatgactca agcctctggc
     2461 tattaacata ccctagttgc cgttttttaa ttgccatgag ccaaatactt cttggtatac
     2521 aattgatcca tttattttaa tggctgcctt ttcattttca tcttttcttg ctgctaccca
     2581 tctatgtatg tagtcattgg ggggaaaatg tagccacatt ttttatggga agactttgtg
     2641 ttaaaagtga acattttgaa ggtttttaac tggtgaaact agcctggaat aatgccacca
     2701 gagactgagt ggaaatcgcc ccttttgaag gtgccattct tatgagccaa aagtttgtca
     2761 tttaaaagtt cattttgagg gaataacatg taatataatt tgaaataaag gtatagtaac
     2821 cttaaaaaga acattataac tgattgttgt gaatggggtg aatttgttaa aatgagtaac
     2881 tttgataaag tttttcatgc acaggcaaaa tgtattcact agatttctac gtagtgatct
     2941 gcttttactt tgtaatttgt agttctcaaa agactttttt ttaaaaaaat aaagtccata
     3001 cttacactta ggctttatac atcagtcttt ttttttttaa attccatgtt aatacctagt
     3061 ggtattgtat gttgtgtgtt cagatgtctt tactgtatct gtataccatt aagtaataat
     3121 tagactccca aactgtaaac cacctacaca gaattctggt gtagctaaaa ctacattaat
     3181 atttctacaa ccaattcatt gcatgtttct tccatacaaa gtgtgccatt ttatactgtg
     3241 tatagtgaaa aagtgtgtca tcttccagaa ctacattatt atctttgatc gtagtttgtt
     3301 tcttcataat gacactgtag tgtttactta gtagaacatt atagtaagtg gatatcactt
     3361 gtgacagtaa tagtgtaaag aaagggaatg ctttataaaa agattgcaga ttccattcca
     3421 tataaaaaga ttccattctg aatcttaagt ggtaatttta gaattcaggt gccagtgcca
     3481 gcctatggcc tcaagtatgt aattcttaat atagatgtta aattgtactt ttaattatga
     3541 ttggataaat gttttttcta actgtcagtt tctaaggctg tctccttaga aactaaatga
     3601 gtttttagag ctggttgtaa gtttcttagc cttactctgt gagttataga tgttatttca
     3661 ttctatatat agatgtttat tccattctta tttaaaaaaa aaaacctcca tataccaaaa
     3721 atgctacagg atattttgaa atagcatatt ttagttaggg gaaatgcatg tgaccaagag
     3781 gttggacttc taattcagtt tttcaaaagc ttttttccat tatcataccc ccagcctttt
     3841 taggcttttt tttttttttt tttgagacgg agtctcgctc tgtcaccagg ctggagtgca
     3901 gtggcgcgat cttggctcac tgcaagttcc gcctcccggg ttcacgccat tctcctgcct
     3961 cagcctcccg agtagctggg actacaggcg cccgccacca tgcccgacta atttttttgt
     4021 atttttagta gagacgaggt ttcaccggat tagcgaggat ggtctcaatc tcctgacctt
     4081 gtgatccacc cgcctcagcc tcccaaagtg ctgggattat gggcttgagc caccgcgccc
     4141 agctagactt ttttctaata gagtccccca taaattttat taccatagat acgctgtgta
     4201 tgtactgttt ctgtgctttg tacatgaaaa gagtaaaatg tttttgtttt tgttttggag
     4261 acagtctcac tctgttacct gggctggagt gcaatggcat gatctcagct cactgcaatc
     4321 tctgcctcct gggttcaagc gattctcttg cttcagcctc ctgagtagct gggattacag
     4381 gcggccacca ccacccctgg ctaatttttg tatttttagt agaggtttca ccacgttgat
     4441 caggctggtc tcaaactcct gacctcgtgg tctgcctgcc ttggcctccc aaagtgctgg
     4501 gattacaggc gtgagccacc atgcccaacc aatttttttt ttttaaatcc ttggtagtga
     4561 ttgaccccca ttgagaatgc atgctctaat attttttaaa agggaagaag acctagtgat
     4621 agacctttgc attggcaggc atgtctttat gtttatacag tgaagtagta ttttttctgt
     4681 cagggtcaat agaaagtaga cgaaattcat tttcagccaa tctttcacca gttgtgcttt
     4741 gttccttacc ccaccacagg caacagacaa agcatttcct gctgtctttc aaggtcttaa
     4801 cagattcttt cttgattata aatgtattac taagtagaat catttgggtt ctttctataa
     4861 aaatcagtga aaatcctcta gatgaatgaa ttaaagttgt aggcataaca ctgataaacc
     4921 tctgctctca tactgaagta ggctgcttgc aggaactgac aactattggt tggctttaaa
     4981 tgtaatgtag atgccaaagt tttagtgtac agtgttactt aaattaccaa attacctttg
     5041 tacaaatatt cctcagatgc tgtctacagg tgccatataa aataggttga taagtatttg
     5101 caaattctgg taaattgcct tgctatgatt tttcatgctc agtattagtc ctctagtatc
     5161 aatacgaagt ttttctattc cccagcctac taaggcctac aggttaaaat accaggaata
     5221 aaaaggtttt cagtggactt gatttaagtg gaatctggat gatgtgacaa gtacctttgt
     5281 ctttggagta atgagtttat aattggcttt tgtccaaaaa ctcttaagtg gattaatatc
     5341 tgaacaatct tagacataat tatatgaaac tggatcagaa aggctttctg actcctttct
     5401 cttcactttt ttctcccagc ttaactagag gcaattaaca gtcatttcaa atctaattat
     5461 ttttattttc cagtgtactt atcatccttt catctttatg ctaggagtat agtctcagtt
     5521 cttaatgagt tgatgggatg aagatataga tagatagata gatagataga tagatagata
     5581 tttttttttt tttttttttt tttttttttt tttttgagac agagtctcgc tctgtcgccc
     5641 aggcgggagt gcagtggcac aatctcggct cactgcaagc tccgccttgg gggttcacac
     5701 cattctcctg tctcagcctc ctagctggga ttacaggcgc ccaccaacca agcccggcta
     5761 aggtattttt aaatgtactc aatcactgtc attttagtaa ccttgaatca gaacctcagt
     5821 tgttaaaggc ttaactgctt gtggcaacta ctatagtgct ctagtgggga cagtggttaa
     5881 aatctgcaga atcccttgct ttgtcatctt atccagaagg actgatagct tgttaaactg
     5941 tggtatgatt agaatgttgg tggttgtgta gtgcatttgg ggtgctacaa cgttaatcaa
     6001 atataattga gctgttctgt ttccagtcag tgtaaccatt taaaaatacc ttggcaaaac
     6061 aagctaggag ctagttcatg ctaatattct taaggacaaa aatagtttac agcttttttt
     6121 tttttaatct gaaatcctga aggctatgct taaaagttag agataaacct gttggaaata
     6181 agtgattcat ttatagactg aagcctctat gacttcaaaa agatactcaa cagtctctgg
     6241 catttgaaga acaaaatatt ttctctgtaa atacacctca tttccattct agttaggagc
     6301 aatggcgccc aggacggcac acagaatgga gaaaactgga tagctggtaa ctcatttagc
     6361 tcttggcact ctaaaaaacc tcaaatacag ccatccaagc cagtaattct attgctgcgt
     6421 tatttctgtg tttaactgtg aaacttgctt cttgtctgta cccttgaaat ggaataaaat
     6481 ttcatgagac tccttgttaa tgtagagaaa a
//
