LOCUS       NM_001136537            2987 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens BTB domain containing 19 (BTBD19), transcript variant
            3, mRNA.
ACCESSION   NM_001136537 XM_001725874
VERSION     NM_001136537.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2987)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL592166.16.
            
            On Oct 26, 2020 this sequence version replaced NM_001136537.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.446346.1,
                                           SRR14038192.509549.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2142680
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000450269.6/ ENSP00000395461.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-384               AL592166.16        72551-72934
            385-598             AL592166.16        74241-74454
            599-652             AL592166.16        74582-74635
            653-712             AL592166.16        76067-76126
            713-781             AL592166.16        77024-77092
            782-913             AL592166.16        77166-77297
            914-1039            AL592166.16        77402-77527
            1040-2987           AL592166.16        77666-79613
FEATURES             Location/Qualifiers
     source          1..2987
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.1"
     gene            1..2987
                     /gene="BTBD19"
                     /note="BTB domain containing 19"
                     /db_xref="GeneID:149478"
                     /db_xref="HGNC:HGNC:27145"
     exon            1..384
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..1174
                     /gene="BTBD19"
                     /note="isoform 3 is encoded by transcript variant 3;
                     BTB/POZ domain-containing protein 19; novel BTB domain
                     containing protein; BTB (POZ) domain containing 19"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein 19 isoform 3"
                     /protein_id="NP_001130009.1"
                     /db_xref="GeneID:149478"
                     /db_xref="HGNC:HGNC:27145"
                     /translation="MEPLGLVVHGKAEPFSAALRSLVNNPRYSDVCFVVGQERQEVFA
                     HRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPTEAFLAVLEFLYTNSVKLYRHSVL
                     EVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIEAHS
                     QEALRTRGFLELSAAALLPLLRSDKLCVDEAELVRAARSWARVGAAVLERPVAEVAAP
                     VVKELRLALLAPAELSALEEQNRQEPLIPVEQIVEAWKCHALRRGDEARGAPCRRRRG
                     TLPREHHRFLDLSFK"
     exon            385..598
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     exon            599..652
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     exon            653..712
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     exon            713..781
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     exon            782..913
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1039
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..2987
                     /gene="BTBD19"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2966..2971
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BTBD19"
                     /note="hexamer: AGTAAA"
     polyA_site      2987
                     /gene="BTBD19"
                     /note="major polyA site"
ORIGIN      
        1 agggcctctt tcgccgccgc cgccgccgcc agccagccag cttcttccca ggaccatagg
       61 ccactccagc ctcagcttct cctggccccc tccctgtgtc tgttcctgtc cccgagcctc
      121 tggcctctga tgccttcagg agcttgggcc tctcctgctc cactcctaaa cttcagcttc
      181 tcagcaaaca ggcctcccaa gtccctgctt ctccctctca ggccttgcta acctcaccag
      241 ctctagggcc tggccaggcc tcccaggctc cctcctccac cccaacccct tctcactcat
      301 ggagcccttg ggactggtcg tgcatgggaa agctgaacct ttttccgcag cactccgaag
      361 ccttgtcaac aacccgcgat acagtgatgt ttgcttcgtg gttggtcaag aacggcagga
      421 ggtatttgcc catcggtgct tgttggcctg tagatgcaac ttcttccagc gacttctggg
      481 cacagagcca ggccccgggg tgcccagtcc tgtggtgcta agcactgtgc caactgaggc
      541 cttcctggca gtgctggagt tcctatatac caacagtgtc aagctgtacc gccactctgt
      601 gctggaagtg ctgacagcgg ctgtggagta tgggctggag gaactgagag agctgtgcct
      661 gcagtttgtg gtgaaggtgc tggatgtgga cttggtttgt gaggccctgc aggtggccgt
      721 aacctttggc ctggggcagc tgcaggagcg ctgcgtggct ttcatagagg cccacagcca
      781 ggaggccctc cggacccgag gcttcctgga gctgtcggcg gccgcgctgc tgcccctgct
      841 ccgcagcgac aagctctgcg tggacgaggc tgaactggtc cgcgcggccc gaagctgggc
      901 gcgcgtgggc gcggcggtgc tggagcggcc ggtggctgag gtggcggccc cggtggtgaa
      961 agagctgaga ctagccttgc tggccccggc ggagctgagc gccctggaag agcagaaccg
     1021 gcaggaacca ctcatcccgg tggagcagat tgtggaggcg tggaaatgcc atgccctgcg
     1081 gagaggggat gaggcccggg gcgccccgtg tcgccgccgg agaggcaccc tgccccggga
     1141 gcatcaccgc tttctggacc tgtccttcaa atgatccaac gccgggactc gcagggagcc
     1201 ctcgacccgc ccagctgagc ctgccccaaa ctacagctcc cgaagtgctc ggcgttcgga
     1261 gcgggcttcc gttcccagcg tgcccagtga gccgggcgcc ggaagaaccg ttgtctgcca
     1321 cgcgcagccc cttgtgcggg atcaagcccg tgtgggcgag gtggggtcgg gccgggcagg
     1381 gcttgggctg ggcctccctg agggggtgaa actcgaaaac gaggatttcc ttcgttccac
     1441 accctgactc tacgccctgc ccctgggcat tgtcgtctac tagtctattc tgatgactcc
     1501 cacatatcta tctgttcagc tcagctccct ctttcttttc tttttctttc tctttctttc
     1561 tttctttctt tctttctttc tttctttctt tctttctttc tttctttctt tctttttctt
     1621 tctttctctt tccttccttc cttccttcct tccttctttc tttctctttc tctatctctt
     1681 tctttctttc tttctttctc tcctctctct tttttttgag acggagtctc gcactctcgc
     1741 ccaggccgga gggcagtggt gccatctcgg ctcactgcaa gctccgcctc ccgggttcac
     1801 gccgttctcc tgcctcagcc tccggagtag ctggtactac aggcgcccat caccacgccc
     1861 ggctaatttt tttgaatttt tagtagagac ggagtttcac cgtattagcc aggatggtct
     1921 cgatctcctg accttgtgat ccgcccgcct cggccttttt tttttttttt ttgagacaga
     1981 gtcttgctct gtcgtcgagg ctggagtgta gtggtgcgat ttcggctcac ttcaaactcc
     2041 gcctcccggg ttcaagcgat tctcgtgcct cagcctcctg agtagctggg attacagaca
     2101 tgcaccacaa cgcccggcta attgttgtat ttttagtaga gacgggggtt tcaccatgtt
     2161 ggccaggttg gtctcgaact cctgacttca tgtgatccgc cagcctcggc ctcccaaagt
     2221 gctgggatta caggtgtgcg ccaccatgcc cggcctcagc tccttctttc attccagacc
     2281 tgcccccctg gagatcgctc cctgaatgcc cctcagacac cacaggctcg gcgagaaatt
     2341 gatctcccca gcttttcccc agctctgccc ccatcgtgtt tctcatttcc gtggacaccc
     2401 acgccagaaa cctggatctc atccttgcct tatcgctctt cacacctgcc ttaggtctct
     2461 ttttaccttg taagagacct taagagacct ttccagttgg ttcagttctc tcagccccag
     2521 gttcaacctg tcctgtctga cacgtctcac agccttcctg ccttcactcc agcgccccct
     2581 caatccattt cccacagtgc agccagacct gtttttgatt gtcagtccta tggggcttaa
     2641 gtcctggaac atcccattga cctccaggac aaaattcaat ctatttcact ttcagggcac
     2701 tcaaaactac tagtgagtgg ttcctcacct cttctctcaa atacaatctt tgtataaatt
     2761 catttatcct ggaggtatta gtcctctagc tccatacctt actcagttac tgcagacccc
     2821 tctgctacct ccttcattca ctatacatct tgttttcccg aggatgtgaa tctccctcaa
     2881 gaaagatccc tggggcctgg agtggtgtct tactcgtttc tgcttcctca gtctctgtca
     2941 gataatcagt gctatgtaaa tgttaagtaa atgactttat ttattta
//
