LOCUS       NM_001136200            2386 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens BLOC-1 related complex subunit 7 (BORCS7), transcript
            variant 1, mRNA.
ACCESSION   NM_001136200
VERSION     NM_001136200.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2386)
  AUTHORS   Tunganuntarat,J., Kanjanasirirat,P., Khumpanied,T.,
            Benjaskulluecha,S., Wongprom,B., Palaga,T., Siregar,T.A.P.,
            Borwornpinyo,S., Chaiprasert,A., Palittapongarnpim,P. and
            Ponpuak,M.
  TITLE     BORC complex specific components and Kinesin-1 mediate autophagy
            evasion by the autophagy-resistant Mycobacterium tuberculosis
            Beijing strain
  JOURNAL   Sci Rep 13 (1), 1663 (2023)
   PUBMED   36717601
  REMARK    GeneRIF: BORC complex specific components and Kinesin-1 mediate
            autophagy evasion by the autophagy-resistant Mycobacterium
            tuberculosis Beijing strain.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2386)
  AUTHORS   D'Ambrosio,E., Dahoun,T., Pardinas,A.F., Veronese,M.,
            Bloomfield,M.A.P., Jauhar,S., Bonoldi,I., Rogdaki,M.,
            Froudist-Walsh,S., Walters,J.T.R. and Howes,O.D.
  TITLE     The effect of a genetic variant at the schizophrenia associated
            AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging
            study
  JOURNAL   Psychiatry Res Neuroimaging 291, 34-41 (2019)
   PUBMED   31386983
  REMARK    GeneRIF: effect of a genetic variant at the schizophrenia
            associated AS3MT/BORCS7 locus on striatal dopamine function: a PET
            imaging study
REFERENCE   3  (bases 1 to 2386)
  AUTHORS   Yordanov,T.E., Hipolito,V.E.B., Liebscher,G., Vogel,G.F.,
            Stasyk,T., Herrmann,C., Geley,S., Teis,D., Botelho,R.J., Hess,M.W.
            and Huber,L.A.
  TITLE     Biogenesis of lysosome-related organelles complex-1 (BORC)
            regulates late endosomal/lysosomal size through PIKfyve-dependent
            phosphatidylinositol-3,5-bisphosphate
  JOURNAL   Traffic 20 (9), 674-696 (2019)
   PUBMED   31314175
REFERENCE   4  (bases 1 to 2386)
  AUTHORS   Das,N., Giri,A., Chakraborty,S. and Bhattacharjee,P.
  TITLE     Association of single nucleotide polymorphism with arsenic-induced
            skin lesions and genetic damage in exposed population of West
            Bengal, India
  JOURNAL   Mutat Res Genet Toxicol Environ Mutagen 809, 50-56 (2016)
   PUBMED   27692299
  REMARK    GeneRIF: Sngle nucleotide polymorphism in c10orf32 gene is
            associated with skin lesions.
REFERENCE   5  (bases 1 to 2386)
  AUTHORS   Li,M., Jaffe,A.E., Straub,R.E., Tao,R., Shin,J.H., Wang,Y.,
            Chen,Q., Li,C., Jia,Y., Ohi,K., Maher,B.J., Brandon,N.J., Cross,A.,
            Chenoweth,J.G., Hoeppner,D.J., Wei,H., Hyde,T.M., McKay,R.,
            Kleinman,J.E. and Weinberger,D.R.
  TITLE     A human-specific AS3MT isoform and BORCS7 are molecular risk
            factors in the 10q24.32 schizophrenia-associated locus
  JOURNAL   Nat Med 22 (6), 649-656 (2016)
   PUBMED   27158905
  REMARK    GeneRIF: Risk alleles spanning multiple genes across the 10q24.32
            schizophrenia-related locus are associated in the human brain
            selectively with an increase in the expression of both BLOC-1
            related complex subunit 7 (BORCS7) and a previously
            uncharacterized, human-specific arsenite methyltransferase (AS3MT)
            isoform (AS3MTd2d3).
REFERENCE   6  (bases 1 to 2386)
  AUTHORS   Ripke,S., O'Dushlaine,C., Chambert,K., Moran,J.L., Kahler,A.K.,
            Akterin,S., Bergen,S.E., Collins,A.L., Crowley,J.J., Fromer,M.,
            Kim,Y., Lee,S.H., Magnusson,P.K., Sanchez,N., Stahl,E.A.,
            Williams,S., Wray,N.R., Xia,K., Bettella,F., Borglum,A.D.,
            Bulik-Sullivan,B.K., Cormican,P., Craddock,N., de Leeuw,C.,
            Durmishi,N., Gill,M., Golimbet,V., Hamshere,M.L., Holmans,P.,
            Hougaard,D.M., Kendler,K.S., Lin,K., Morris,D.W., Mors,O.,
            Mortensen,P.B., Neale,B.M., O'Neill,F.A., Owen,M.J.,
            Milovancevic,M.P., Posthuma,D., Powell,J., Richards,A.L.,
            Riley,B.P., Ruderfer,D., Rujescu,D., Sigurdsson,E., Silagadze,T.,
            Smit,A.B., Stefansson,H., Steinberg,S., Suvisaari,J., Tosato,S.,
            Verhage,M., Walters,J.T., Levinson,D.F., Gejman,P.V., Kendler,K.S.,
            Laurent,C., Mowry,B.J., O'Donovan,M.C., Owen,M.J., Pulver,A.E.,
            Riley,B.P., Schwab,S.G., Wildenauer,D.B., Dudbridge,F., Holmans,P.,
            Shi,J., Albus,M., Alexander,M., Campion,D., Cohen,D., Dikeos,D.,
            Duan,J., Eichhammer,P., Godard,S., Hansen,M., Lerer,F.B.,
            Liang,K.Y., Maier,W., Mallet,J., Nertney,D.A., Nestadt,G.,
            Norton,N., O'Neill,F.A., Papadimitriou,G.N., Ribble,R.,
            Sanders,A.R., Silverman,J.M., Walsh,D., Williams,N.M., Wormley,B.,
            Arranz,M.J., Bakker,S., Bender,S., Bramon,E., Collier,D.,
            Crespo-Facorro,B., Hall,J., Iyegbe,C., Jablensky,A., Kahn,R.S.,
            Kalaydjieva,L., Lawrie,S., Lewis,C.M., Lin,K., Linszen,D.H.,
            Mata,I., McIntosh,A., Murray,R.M., Ophoff,R.A., Powell,J.,
            Rujescu,D., Van Os,J., Walshe,M., Weisbrod,M., Wiersma,D.,
            Donnelly,P., Barroso,I., Blackwell,J.M., Bramon,E., Brown,M.A.,
            Casas,J.P., Corvin,A.P., Deloukas,P., Duncanson,A., Jankowski,J.,
            Markus,H.S., Mathew,C.G., Palmer,C.N., Plomin,R., Rautanen,A.,
            Sawcer,S.J., Trembath,R.C., Viswanathan,A.C., Wood,N.W.,
            Spencer,C.C., Band,G., Bellenguez,C., Freeman,C., Hellenthal,G.,
            Giannoulatou,E., Pirinen,M., Pearson,R.D., Strange,A., Su,Z.,
            Vukcevic,D., Donnelly,P., Langford,C., Hunt,S.E., Edkins,S.,
            Gwilliam,R., Blackburn,H., Bumpstead,S.J., Dronov,S., Gillman,M.,
            Gray,E., Hammond,N., Jayakumar,A., McCann,O.T., Liddle,J.,
            Potter,S.C., Ravindrarajah,R., Ricketts,M.,
            Tashakkori-Ghanbaria,A., Waller,M.J., Weston,P., Widaa,S.,
            Whittaker,P., Barroso,I., Deloukas,P., Mathew,C.G., Blackwell,J.M.,
            Brown,M.A., Corvin,A.P., McCarthy,M.I., Spencer,C.C., Bramon,E.,
            Corvin,A.P., O'Donovan,M.C., Stefansson,K., Scolnick,E.,
            Purcell,S., McCarroll,S.A., Sklar,P., Hultman,C.M. and
            Sullivan,P.F.
  CONSRTM   Multicenter Genetic Studies of Schizophrenia Consortium; Psychosis
            Endophenotypes International Consortium; Wellcome Trust Case
            Control Consortium 2
  TITLE     Genome-wide association analysis identifies 13 new risk loci for
            schizophrenia
  JOURNAL   Nat Genet 45 (10), 1150-1159 (2013)
   PUBMED   23974872
REFERENCE   7  (bases 1 to 2386)
  AUTHORS   Eeles,R.A., Olama,A.A., Benlloch,S., Saunders,E.J.,
            Leongamornlert,D.A., Tymrakiewicz,M., Ghoussaini,M., Luccarini,C.,
            Dennis,J., Jugurnauth-Little,S., Dadaev,T., Neal,D.E., Hamdy,F.C.,
            Donovan,J.L., Muir,K., Giles,G.G., Severi,G., Wiklund,F.,
            Gronberg,H., Haiman,C.A., Schumacher,F., Henderson,B.E., Le
            Marchand,L., Lindstrom,S., Kraft,P., Hunter,D.J., Gapstur,S.,
            Chanock,S.J., Berndt,S.I., Albanes,D., Andriole,G., Schleutker,J.,
            Weischer,M., Canzian,F., Riboli,E., Key,T.J., Travis,R.C.,
            Campa,D., Ingles,S.A., John,E.M., Hayes,R.B., Pharoah,P.D.,
            Pashayan,N., Khaw,K.T., Stanford,J.L., Ostrander,E.A.,
            Signorello,L.B., Thibodeau,S.N., Schaid,D., Maier,C., Vogel,W.,
            Kibel,A.S., Cybulski,C., Lubinski,J., Cannon-Albright,L.,
            Brenner,H., Park,J.Y., Kaneva,R., Batra,J., Spurdle,A.B.,
            Clements,J.A., Teixeira,M.R., Dicks,E., Lee,A., Dunning,A.M.,
            Baynes,C., Conroy,D., Maranian,M.J., Ahmed,S., Govindasami,K.,
            Guy,M., Wilkinson,R.A., Sawyer,E.J., Morgan,A., Dearnaley,D.P.,
            Horwich,A., Huddart,R.A., Khoo,V.S., Parker,C.C., Van As,N.J.,
            Woodhouse,C.J., Thompson,A., Dudderidge,T., Ogden,C., Cooper,C.S.,
            Lophatananon,A., Cox,A., Southey,M.C., Hopper,J.L., English,D.R.,
            Aly,M., Adolfsson,J., Xu,J., Zheng,S.L., Yeager,M., Kaaks,R.,
            Diver,W.R., Gaudet,M.M., Stern,M.C., Corral,R., Joshi,A.D.,
            Shahabi,A., Wahlfors,T., Tammela,T.L., Auvinen,A., Virtamo,J.,
            Klarskov,P., Nordestgaard,B.G., Roder,M.A., Nielsen,S.F.,
            Bojesen,S.E., Siddiq,A., Fitzgerald,L.M., Kolb,S., Kwon,E.M.,
            Karyadi,D.M., Blot,W.J., Zheng,W., Cai,Q., McDonnell,S.K.,
            Rinckleb,A.E., Drake,B., Colditz,G., Wokolorczyk,D.,
            Stephenson,R.A., Teerlink,C., Muller,H., Rothenbacher,D.,
            Sellers,T.A., Lin,H.Y., Slavov,C., Mitev,V., Lose,F.,
            Srinivasan,S., Maia,S., Paulo,P., Lange,E., Cooney,K.A.,
            Antoniou,A.C., Vincent,D., Bacot,F., Tessier,D.C., Kote-Jarai,Z.
            and Easton,D.F.
  CONSRTM   COGS-Cancer Research UK GWAS-ELLIPSE (part of GAME-ON) Initiative;
            Australian Prostate Cancer Bioresource; UK Genetic Prostate Cancer
            Study Collaborators/British Association of Urological Surgeons'
            Section of Oncology; UK ProtecT (Prostate testing for cancer and
            Treatment) Study Collaborators; PRACTICAL (Prostate Cancer
            Association Group to Investigate Cancer-Associated Alterations in
            the Genome) Consortium
  TITLE     Identification of 23 new prostate cancer susceptibility loci using
            the iCOGS custom genotyping array
  JOURNAL   Nat Genet 45 (4), 385-391 (2013)
   PUBMED   23535732
REFERENCE   8  (bases 1 to 2386)
  AUTHORS   Pierce,B.L., Kibriya,M.G., Tong,L., Jasmine,F., Argos,M., Roy,S.,
            Paul-Brutus,R., Rahaman,R., Rakibuz-Zaman,M., Parvez,F., Ahmed,A.,
            Quasem,I., Hore,S.K., Alam,S., Islam,T., Slavkovich,V.,
            Gamble,M.V., Yunus,M., Rahman,M., Baron,J.A., Graziano,J.H. and
            Ahsan,H.
  TITLE     Genome-wide association study identifies chromosome 10q24.32
            variants associated with arsenic metabolism and toxicity phenotypes
            in Bangladesh
  JOURNAL   PLoS Genet 8 (2), e1002522 (2012)
   PUBMED   22383894
REFERENCE   9  (bases 1 to 2386)
  AUTHORS   Simon-Sanchez,J., Schulte,C., Bras,J.M., Sharma,M., Gibbs,J.R.,
            Berg,D., Paisan-Ruiz,C., Lichtner,P., Scholz,S.W., Hernandez,D.G.,
            Kruger,R., Federoff,M., Klein,C., Goate,A., Perlmutter,J.,
            Bonin,M., Nalls,M.A., Illig,T., Gieger,C., Houlden,H., Steffens,M.,
            Okun,M.S., Racette,B.A., Cookson,M.R., Foote,K.D., Fernandez,H.H.,
            Traynor,B.J., Schreiber,S., Arepalli,S., Zonozi,R., Gwinn,K., van
            der Brug,M., Lopez,G., Chanock,S.J., Schatzkin,A., Park,Y.,
            Hollenbeck,A., Gao,J., Huang,X., Wood,N.W., Lorenz,D., Deuschl,G.,
            Chen,H., Riess,O., Hardy,J.A., Singleton,A.B. and Gasser,T.
  TITLE     Genome-wide association study reveals genetic risk underlying
            Parkinson's disease
  JOURNAL   Nat Genet 41 (12), 1308-1312 (2009)
   PUBMED   19915575
REFERENCE   10 (bases 1 to 2386)
  AUTHORS   Adams,M.D., Kerlavage,A.R., Fleischmann,R.D., Fuldner,R.A.,
            Bult,C.J., Lee,N.H., Kirkness,E.F., Weinstock,K.G., Gocayne,J.D.,
            White,O. et al.
  TITLE     Initial assessment of human gene diversity and expression patterns
            based upon 83 million nucleotides of cDNA sequence
  JOURNAL   Nature 377 (6547 Suppl), 3-174 (1995)
   PUBMED   7566098
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA006534.1, AK098071.1, AL832477.1, BP419064.1, AI147530.1,
            AA299084.1 and AW058660.1.
            
            On May 17, 2019 this sequence version replaced NM_001136200.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.65601.1,
                                           SRR3476690.702236.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000339834.10/ ENSP00000342331.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 DA006534.1         50-52
            4-738               AK098071.1         1-735
            739-773             AL832477.1         776-810
            774-2065            AK098071.1         772-2063
            2066-2141           BP419064.1         451-526
            2142-2253           AI147530.1         8-119               c
            2254-2260           AA299084.1         20-26
            2261-2386           AW058660.1         16-141              c
FEATURES             Location/Qualifiers
     source          1..2386
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q24.32"
     gene            1..2386
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="BLOC-1 related complex subunit 7"
                     /db_xref="GeneID:119032"
                     /db_xref="HGNC:HGNC:23516"
                     /db_xref="MIM:616600"
     exon            1..169
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..349
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="UPF0693 protein C10orf32; diaskedin"
                     /codon_start=1
                     /product="BLOC-1-related complex subunit 7"
                     /protein_id="NP_001129672.1"
                     /db_xref="CCDS:CCDS7542.2"
                     /db_xref="GeneID:119032"
                     /db_xref="HGNC:HGNC:23516"
                     /db_xref="MIM:616600"
                     /translation="MMATGTPESQARFGQSVKGLLTEKVTTCGTDVIALTKQVLKGSR
                     SSELLGQAARNMVLQEDAILHSEDSLRKMAIITTHLQYQQEAIQKNVEQSSDLQDQLN
                     HLLK"
     exon            170..232
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            233..276
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            277..297
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            298..2386
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1816..1821
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="hexamer: AATACA"
     polyA_site      1832
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="major polyA site"
     regulatory      1895..1900
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="hexamer: AAGAAA"
     polyA_site      1919
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
     regulatory      2193..2198
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="hexamer: AATAAA"
     regulatory      2212..2217
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="hexamer: ATTAAA"
     polyA_site      2217
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
     polyA_site      2241
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
     regulatory      2248..2253
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="hexamer: ACTAAA"
     polyA_site      2269
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
     regulatory      2324..2329
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
                     /note="hexamer: AAGAAA"
     polyA_site      2344
                     /gene="BORCS7"
                     /gene_synonym="C10orf32"
ORIGIN      
        1 gtcagtgcgc aaccgttcgc taactgaaat gatggcgact ggaacgccag agtctcaagc
       61 gcggttcggt cagtccgtga aggggcttct cacggagaag gtgaccacct gtggtactga
      121 cgtaatcgcg ctcaccaagc aggtgctgaa aggctcccgg agctccgagc tgctaggtca
      181 ggcagctcga aacatggtac tccaggaaga tgccatcttg cactcagaag atagtttaag
      241 gaagatggca ataataacaa cacatcttca ataccagcaa gaagctattc agaagaatgt
      301 tgaacagtca tcggatctac aggaccagtt gaatcatctg ttgaaataga atgacatgta
      361 agagtgctgt aggactcctt tgcctaatgc tgaggagtaa ataccttaca cagctgtcct
      421 ctgggtttgg ttttctattt tcttctccaa aagttaagtt agaaaagttc tgtgttaggg
      481 ccgggcgcgg tagctcacgc ctgtaatccc agcactttgg gaggccgagg cgggtggatc
      541 acgaggtcag gagttcgaga ccagcctggc caagatggtg aaaccccgtc tctactaaaa
      601 atacaaagaa ttagctgggc gtggtggcgg gcgcctgtaa tcccagctac tcgggaagct
      661 gaggcaagag aatcgcttga acccaggagg tggaggttgc agtgagccaa gatcgcgcca
      721 ctgcactcca gcctgggcga cagagtgaga ttccatctcc aaaaaaaaaa aaagaaaaaa
      781 aaaagaaaag ttctgtgttg atgtacagtt tctcctaaga agaagcgagg tggttgaatt
      841 ttggaagcac ttcttgaatc ggattaaccc atgctcttat tgaatttttt catctgctct
      901 gtttagtttg atattaaagc aaaattaaga ggtcttagtt tttcctatag aacttttaat
      961 atgtcaaaag ctatattgtc taaatttcag tacttaagca aatactgagt agtgttttaa
     1021 attcagaaat agagcttcta ttatgaacac atgagaatga tttttttctc ttaatcatta
     1081 ttaaggaaat attttaattt catggtcata taatggtgat aagtaatacc tgattgtttc
     1141 cttttctgtt ctagtaactc agaggagata cgtgttttat ttgtgatagc aaattcctaa
     1201 atgaacatta ggcaagtggt atcattatca ggccagctgc agcctcttgc cttgacctgc
     1261 attcctagaa tttctttgtt gctgtaattc ttgattaagt gaccttgact ttcattttgt
     1321 aattttgcta atcatcagca aattcacttg catgacgtta ctgccaaata tgaaggcagt
     1381 tgaattatta tgagtgattg tggcagaggt ttgtgccatg gtgaaaactt tgatgtttgt
     1441 ctgtgttcat tggatccatc tttttaaatg acattaccat gagtctgttg tcaaacctaa
     1501 atatctttgt ttgaatttaa aatgggactc tatattgttg tagttcaggt cttcattgac
     1561 taagagattg agagaaatct gacataagaa aatattgttt tcactgcagg aataaagagg
     1621 aagtaacagt gaatccaata tagttcatat tgttattgtc caatcatcaa gttaactaag
     1681 cattatcaga ttacgtttat ttctcataca tatggatatt aacttaaggt aaaaaagctg
     1741 gatgtgaagg atctgaaaag gcattaattt atgtactaat tctataaaca tgtattaata
     1801 attgcagtat tattaaatac agatggactc aatgtacctt tgaaaagacc actaatttag
     1861 aaaacaaagc taagtgcagt cattacaaga agcaaagaaa tacttaagtt agaaaaaaat
     1921 taaaatgaag ggatggtcta agttttcttc atgctggaac aaatgttaaa gaagcagtga
     1981 ttgcttacaa tgtatgtgat aaaataatac ctttcacaat caaaatttta atagtaaata
     2041 taagataaaa tttatattaa ataatgaaaa cgtatttgta ctgaatttag tcactagaga
     2101 acatcgtaac aaaatacatg aaacaaaagt agccagaaat gttagaacag gtggaaatgt
     2161 atacattatt tgatggtttg tttttttatg gaaataaaca acatacatag aattaaatgg
     2221 tgatcaaaaa catggaaaaa atacttcact aaataacgtc taagttgtag aggttgtgcc
     2281 ggaagataat atttttaaaa taacaaatgt tcaaatgcca taaaagaaaa tttgtgtgat
     2341 aataccaaag cagtactata agaaaataag catgctttaa atccct
//
