LOCUS       XM_011514817            8314 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens bone morphogenetic protein 5 (BMP5),
            transcript variant X1, mRNA.
ACCESSION   XM_011514817
VERSION     XM_011514817.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011514817.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8314
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..8314
                     /gene="BMP5"
                     /note="bone morphogenetic protein 5; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 33
                     ESTs, 96 long SRA reads, 1 Protein, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 49 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:653"
                     /db_xref="HGNC:HGNC:1072"
                     /db_xref="MIM:112265"
     CDS             726..1799
                     /gene="BMP5"
                     /codon_start=1
                     /product="bone morphogenetic protein 5 isoform X1"
                     /protein_id="XP_011513119.1"
                     /db_xref="GeneID:653"
                     /db_xref="HGNC:HGNC:1072"
                     /db_xref="MIM:112265"
                     /translation="MHLTVFLLKGIVGFLWSCWVLVGYAKGGLGDNHVHSSFIYRRLR
                     NHERREIQREILSILGLPHRPRPFSPGKQASSAPLFMLDLYNAMTNEENPEESEYSVR
                     ASLAEETRGARKGYPASPNGYPRRIQLSRTTPLTTQSPPLASLHDTNFLNDADMVMSF
                     VNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDRSNNRFENETIKISI
                     YQIIKEYTNRDADLFLLDTRKAQALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETG
                     DGRSINVKSAGLVGRQGPQSKQPFMVAFFKASEVLLRSVRAANKRKNQNRNKSSSHQD
                     SSRMSSVGETLHKTTRWNSLDFS"
     polyA_site      8314
                     /gene="BMP5"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 actctttaga tctctcttga agagggctgg tatatttgtg cctgctggag gtggaattaa
       61 cagtaagaag gagaaaggga ttgaatggac ttacaggaag gatttcaagt aaattcaggg
      121 aaacacattt acttgaatag tacaacctag agtattattt tacactaaga cgacacaaaa
      181 gatgttaaag ttatcaccaa gctgccggac agatatatat tccaacacca aggtgcagat
      241 cagcatagat ctgtgattca gaaatcagga tttgttttgg aaagagctca agggttgaga
      301 agaactcaaa agcaagtgaa gattactttg ggaactacag tttatcagaa gatcaacttt
      361 tgctaattca aataccaaag gcctgattat cataaattca tataggaatg cataggtcat
      421 ctgatcaaat aatattagcc gtcttctgct acatcaatgc agcaaaaact cttaacaact
      481 gtggataatt ggaaatctga gtttcagctt tcttagaaat aactactctt gacatattcc
      541 aaaatattta aaataggaca ggaaaatcgg tgaggatgtt gtgctcagaa atgtcactgt
      601 catgaaaaat aggtaaattt gttttttcag ctactgggaa actgtacctc ctagaacctt
      661 aggttttttt tttttttaag aggacaagaa ggactaaaaa tatcaacttt tgcttttgga
      721 caaaaatgca tctgactgta tttttactta agggtattgt gggtttcctc tggagctgct
      781 gggttctagt gggttatgca aaaggaggtt tgggagacaa tcatgttcac tccagtttta
      841 tttatagaag actacggaac cacgaaagac gggaaataca aagggaaatt ctctctatct
      901 tgggtttgcc tcacagaccc agaccatttt cacctggaaa acaagcgtcc tctgcacctc
      961 tctttatgct ggatctctac aatgccatga ccaatgaaga aaatcctgaa gagtcggagt
     1021 actcagtaag ggcatccttg gcagaagaga ccagaggggc aagaaaggga tacccagcct
     1081 ctcccaatgg gtatcctcgt cgcatacagt tatctcggac gactcctctg accacccaga
     1141 gtcctcctct agccagcctc catgatacca actttctgaa tgatgctgac atggtcatga
     1201 gctttgtcaa cttagttgaa agagacaagg atttttctca ccagcgaagg cattacaaag
     1261 aatttcgatt tgatcttacc caaattcctc atggagaggc agtgacagca gctgaattcc
     1321 ggatatacaa ggaccggagc aacaaccgat ttgaaaatga aacaattaag attagcatat
     1381 atcaaatcat caaggaatac acaaataggg atgcagatct gttcttgtta gacacaagaa
     1441 aggcccaagc tttagatgtg ggttggcttg tctttgatat cactgtgacc agcaatcatt
     1501 gggtgattaa tccccagaat aatttgggct tacagctctg tgcagaaaca ggggatggac
     1561 gcagtatcaa cgtaaaatct gctggtcttg tgggaagaca gggacctcag tcaaaacaac
     1621 cattcatggt ggccttcttc aaggcgagtg aggtacttct tcgatccgtg agagcagcca
     1681 acaaacgaaa aaatcaaaac cgcaataaat ccagctctca tcaggactcc tccagaatgt
     1741 ccagtgttgg agagacgctc cataaaacta ctaggtggaa ttcattggac ttttcctaaa
     1801 gggtaggcac caggagaatc acgttagaag tcctatttgt gtggcaagca acagaagcag
     1861 gagggaagat ttctgtatgg aattgcatta tactgaatta aatgctgctt ataaggtgat
     1921 gttttaaaat aattttccaa caaagaaatt taaccacttt tagtaaagca tgacactagt
     1981 gccttattac aacgctattt tttaaagata ttcacaagat atttagtttg gcaaaaagct
     2041 gtaattactt aatatgaaag atggagaaaa ataactttct aagacctttt cttcctggta
     2101 aatactaggc tgtcaaactt gtatattttt cttttcatgt agaatggttc taagtttggt
     2161 tgaaatgttt ttaatttaat gtagcagact gtattaagaa aaagttttgc taaaccttga
     2221 atagaatagt aaataatttt ggaggaaatt acaaagggaa aagtataagt cacatactta
     2281 ttatttgagc tcataatgac tctggcagag gtgttccggt gactgaaatc atcaaagtcc
     2341 ttttccctat tggttaactc tatttatctt ctcttcctaa ccacaagaaa caaatgtacg
     2401 tctataagca gagatgaata aaacacatgg agcagaaatc acgtaacttt tcaccagttt
     2461 cctaacacca tttagagtac aaaattattc taatatagac caatattttc tttttgaaat
     2521 tttgtcattg gcaaccattt ctgtgaaata tgtggtagat ggttttggag tgtgttcata
     2581 ttttgataag aagaagaaag aaagtagctg gtttgtgtct ataagactta acctttcaat
     2641 aggtagtaat caagcagtct gggaaaatcc tcataggatt tggtctaaaa gacaaggctt
     2701 taaggaaagg gaatgctaat ataaacagaa aatttgatac ttcagagact tgaaatgcca
     2761 gtgaaattta aaaattatcc aaatataaat aacaaagttg taatagtaac tagattttac
     2821 aataagatat tgtgcaaagg ctctatggat aagaaggggt gggatgggga tggagttagg
     2881 gaggaaagtt gtattgcctg tttgcctgat tgctgggttt tttgcaaagc atattatcaa
     2941 atgttgaaaa tctccattag tacagaagaa ttaaaaccca agtcatttct gctatcttta
     3001 tcacatttct tttctacttc aacgattctt ccttctgact tcctgatgtt ctttttttct
     3061 tccatattcc tgtgggagag cttagaacag aaaccagcac agaataggag tccccaaaat
     3121 acttgttgag taaattaacg tgctgacagc ataggaaaaa ctaacttcgt ttttcaagta
     3181 aaggtatata gaaccattac ttccaggttt cctgcagaaa ctgcccggca ctgcttgttc
     3241 ctcttcaggt ttttggcaag atggttgaac agacacattg tggaagatat ttcctgtttc
     3301 atgttgaggc agtgcaaagg gtatttcttt gaatttgtgt atgagaggaa agaaaatgga
     3361 gccaatagct aaattctaag ctagctatcc ttgaagatat aaaggcacta ggtggataag
     3421 atttttttaa aaacctccag aacatgatgc tgcttgaagg agtatattca gtgttgaaaa
     3481 gaatagagta caggcatacc atgttttatt gcattttgct ttattgtgtt tcaaagataa
     3541 tgtgtttttt acaaactgaa gttttgtggc agtcctgcat taagcaagtc tattggtgac
     3601 attttttcca acagcatttg tttacttggt ttctctgtgt cacattttgg taatttttgc
     3661 aatatttcaa aattttactg ttattattat atttgttatg gtttatgtta tcagtgatct
     3721 ttgatattta ttggtaattg ttttgtgaca ccacaaattt tacccatata agatgggaag
     3781 taaatgttgt gtgtgttctg attgctccaa cgatcggtca ttaccccatc tctttccctt
     3841 ctcttgggtt ccctattccc tgagacacaa tattgaaata agttcagtta gtacccgaca
     3901 atggcctaaa agtgttcaaa tgaaaggaag atttaaacat ctctcacttt aaatcaaaag
     3961 ctagtaatga ttacgcttat tgaggaaggt atgttgaaag tccagataga ttgaaagcta
     4021 ggcctcttgt gccaaacaaa cagttgtcaa gttgtgactg caaaggaaaa gtacttgaag
     4081 aaaattataa gtatgacttc atcaacacaa taatgataag aaagcgaaat cgttttcttg
     4141 ctgatgtgga gaacgtttga gtggtctgga tggaagatca aaccagccac aacattcctt
     4201 tataccaaag ccttattcag agcaaagccc tgattctcct caattctatg aaggctgaga
     4261 gagctgagga agctgcagaa gaaaagtctg aaagtagcag atattggttc atgacgttta
     4321 aggaaagaag ctgtctccat agcaaaaaag tgcaaggtga aacagcaagt attgatgaag
     4381 aagctatagc aagttatcca ggagatctat ctaagatcac tgatgaaggt agctacactg
     4441 aaccacagat ttttaatgga gattaagaag ccttattgga agatgttatg taggactttc
     4501 atagctagag aagagtcaat ggctggcttc aaatcttctg acaatctgac tctcttgtta
     4561 tgggctaata tacctggtga gattaaattg aagacaatgc tcatttacca ttctgaaaat
     4621 ccttggaccc ctaagtatca tgattaatct actcttcctg ggctctgcaa atggaagaac
     4681 aaaacctgga tgaacagtgc atctgttgat agcatggttt attaactatt ttaggcaaac
     4741 tgttgagacc tattgtccag aaaaaagatt cctttcaaaa tattagtgcc cattgacaat
     4801 gtacttgatc acccaagagc tctgatggag atatacgagt agactaattg tttttatcat
     4861 gcttgctagc acaacatcca ttctgctgcc catgcatgaa agagtagttt tgacttccaa
     4921 gttttattat tttaaagatt tattttgtaa ttctacagct tccataaata gtgattcccc
     4981 tgaaggatct aggcaacctt ctggaaagga ttcaccattc tagattccat ttaagaacac
     5041 tcatgattta tgaggggttg aaatatcaac attaacaagg gtttggaaga agttgattcc
     5101 tacctcctgg atgactttga tgggttcaag acttcagtgg aggaaatcat tgcagttgtg
     5161 gtagaaatag caagagaact tgaattacaa gcggaacctg aatatatgac tggattgctg
     5221 caatctcata ataaaacttg aatgaatgag gagttgcttc ttatggttga gcaaaaaaag
     5281 tggtttctgg atataaaatc ttcctggtga agatactgtg aatgcaattg taatgacaac
     5341 aaaggattta gcattttaaa taagtttatt tactagagta gaggcaggat ttgagaagat
     5401 ggactccaat tttaaaagaa gaccttcaca aagtaaagtg ctatcaaaca gccttgcaca
     5461 ctacacaaag aatcttttgt gaaaggaaga gtcaatcaat gtgacaaatt ttatcgttgt
     5521 cttttaagaa attgccacag ccacatcaac cttcagcaat caccaacctg atcagtcagc
     5581 aggtatcaac attgaggcaa gaccctttac tagcaaaagg attacaactt gctgaagact
     5641 cagatgatca ctagcatttt ttaatcaata gattattttt aactaaggta tgtacatttt
     5701 taaagatata atccaattac acacttaatt gactgtagta taatgtaacc ataactttta
     5761 catgcactgg gaaaccaaaa aatattgtga cactcacttt attgtgacgt tcacttcatt
     5821 gcagtggtct ggaactaaat tcacaatatc tccccagtaa atgtctctga catatgcctg
     5881 tatgaagaat ccaaaagaat taacagggca aatggcaagt cctggatcat tacagaactg
     5941 ctaagaaaga ttgctattgt atgctggata ctgagaatct tcgaaaaata atccaatcat
     6001 gtagtggccc tgcctacatc catggtgatt tcgtagggca agtctttggt atacaggtgc
     6061 tcttcaactt aaaatggggt tatatcccaa taaacccaaa taaagtttgc agtaccataa
     6121 gctcaaatat catagcttag cctagcctcc cttacacatg cccataacat ttacattagc
     6181 ctacagctgg gcaaactcat ctaaaacaag gcctatttca taattaagtt ttgaatatct
     6241 tatgtaattt attggacact ctactgaaag tgaaaaacag aatgcttgtg tgggtactca
     6301 tagtatgatt tctactgaat gtgtattgct ttcaaaccat catcaattta aaaaatctta
     6361 agtcaaagca ttgtaaatca gataaaatgc atagttacta aaattgaaac attctattct
     6421 tgttctcaaa tttgataggc gctatctctt gcctaataaa tacaatgtaa atttatgcct
     6481 cttggaaaaa cagatattag tcaaaacaag aaaataatta attgaagtta tttccatcga
     6541 atgttttata ttatataatt aatacactgt tttagtgttt agaaataata aaatcataaa
     6601 taaagctaaa gttctccctt gtttacctaa tccatacata atagattacc ttaatatgct
     6661 gatatcaaca tggtacaaac ctctctctca tctcttttga gagaatgtat ttttgttata
     6721 tgcttttaat tacatgaatt atatatttta caggttttat aaacaatgtt tagccatatg
     6781 tcaaataacg tgagctaatt cttttcaact gttgcagctt agtattggca tcagtttatt
     6841 taatcatgtc actccaaaaa gacattttgc tttttttcca agttggcact ctcaaaataa
     6901 atgctgtact gaaaatcctg caatgctgca caagtgagaa tatttctaat ccacgtaatt
     6961 atgacagtaa ctaatattaa aagttgctat ctgtgccctg aatcatgaaa aattctggaa
     7021 acccctcctg aaacaagtat gttgatgcat atagtatgtc gttagctagc tctctctatc
     7081 tatatattta tctatcatct atccatcact taatatctaa tactgacttc actacttact
     7141 agttgtataa tcttgcacaa gatatattac ctctctctga ctgtttcctc atgtataaag
     7201 tgggaatgtt aattatacct gccttgcaga gcaggattac aagagttctg aggattaaat
     7261 gagttattat atataactaa tttaaaatag tggtacacgg caaatgctca ttaagtgttg
     7321 aacattataa ttggttttat agaactggta caaaaggagt tcaaactctt acatcagaga
     7381 aaaccagaag ttcacactct ctcttataag tactcatacc tgtggtcaca ggatttctta
     7441 tcttttgaga ctttagaagc aagagaaatt ttagtcttta acctaatttg gctaatctat
     7501 attagcaatt aactacacac tttaaaaaag acttgccaat agacattaag gcattgtgtc
     7561 tgttgttaaa tttctctcta ggaaaaatcc acaggaagaa tatatctggg tataatttct
     7621 tataaataat atttattcaa tatcaaataa actcccatta tatgccaggc acagcattat
     7681 atgctatata actatatgcc atgcactata ttaactatat ggcccaaaat actacatgag
     7741 ggacttatct gagaataaat agacattttc tagaattaac agacatggat gaaaccattt
     7801 caggttgtag aaatgaaatg gctctacagt tgtagagcca tggaccattg tcaaatggct
     7861 ggggtatgca tgtattttta tgtgagagga atgtggtatc agctaggaaa ttattaaggg
     7921 gccaaatcat aaagagtagg gtatgtgatg ataaggagca gtgatgtctt cccataggca
     7981 attggaaaaa gaagaatcat aaccagatat gcattttaaa aagttaattt tggccatgga
     8041 gtgcagaatg gaatgccaag ggtggagaca gaaaactcaa ataatgatta gggtctagta
     8101 taatactcca agcaatgaag atcatagatt ggagagagag atgtaagaac caaaacacac
     8161 tggataaggc cagcaggggt ttgaagaggg tggataaccc aggactctgg agaggggagt
     8221 gttgagagta agtggaatgt gtagggaaaa gatatagcta taagccaaat tgttagatgt
     8281 aggatgaggc tgaccaaatg ccacaggaaa caaa
//
