LOCUS       XM_011521882            2843 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens BLM RecQ like helicase (BLM), transcript
            variant X2, mRNA.
ACCESSION   XM_011521882
VERSION     XM_011521882.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011521882.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2843
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..2843
                     /gene="BLM"
                     /gene_synonym="BS; MGRISCE1; RECQ2; RECQL2; RECQL3"
                     /note="BLM RecQ like helicase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     mRNAs, 13 ESTs, 120 long SRA reads, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 8 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:641"
                     /db_xref="HGNC:HGNC:1058"
                     /db_xref="MIM:604610"
     CDS             100..2823
                     /gene="BLM"
                     /gene_synonym="BS; MGRISCE1; RECQ2; RECQL2; RECQL3"
                     /codon_start=1
                     /product="recQ-like DNA helicase BLM isoform X2"
                     /protein_id="XP_011520184.1"
                     /db_xref="GeneID:641"
                     /db_xref="HGNC:HGNC:1058"
                     /db_xref="MIM:604610"
                     /translation="MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSD
                     NNVSVTNVSVAKTPVLRNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRG
                     GSKSLLPDFLQTPKEVVCTTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDF
                     DTSETSKSFVTPPQSHFVRVSTAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQI
                     DLTEEQKDDSEWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLE
                     EAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDV
                     LSTSKDLLSKPEKMSMQELNPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLK
                     LLDCGNELLQQRNIRRKLLTEVDFNKSDASLLGSLWRYRPDSLDGPMEGDSCPTGNSM
                     KELNFSHLPSNSVSPGDCLLTTTLGKTGFSATRKNLFERPLFNTHLQKSFVSSNWAET
                     PRLGKKNESSYFPGNVLTSTAVKDQNKHTASINDLERETQPSYDIDNFDIDDFDDDDD
                     WEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQ
                     NYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLG
                     EDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGD
                     KTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
                     CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVIVQP
                     SPISKFTAFLSPQRETWYPLAAAPHLLPLVCARLLSLSVVFKGHPCCSIGQ"
ORIGIN      
        1 ccggcgggaa gtgagccagg gcttggcgcg gcggccgtgg ttgcggcgcg ggaagtttgg
       61 atcctggttc cgtccgctag gagtctgcgt gcgaggatta tggctgctgt tcctcaaaat
      121 aatctacagg agcaactaga acgtcactca gccagaacac ttaataataa attaagtctt
      181 tcaaaaccaa aattttcagg tttcactttt aaaaagaaaa catcttcaga taacaatgta
      241 tctgtaacta atgtgtcagt agcaaaaaca cctgtattaa gaaataaaga tgttaatgtt
      301 accgaagact tttccttcag tgaacctcta cccaacacca caaatcagca aagggtcaag
      361 gacttcttta aaaatgctcc agcaggacag gaaacacaga gaggtggatc aaaatcatta
      421 ttgccagatt tcttgcagac tccgaaggaa gttgtatgca ctacccaaaa cacaccaact
      481 gtaaagaaat cccgggatac tgctctcaag aaattagaat ttagttcttc accagattct
      541 ttaagtacca tcaatgattg ggatgatatg gatgactttg atacttctga gacttcaaaa
      601 tcatttgtta caccacccca aagtcacttt gtaagagtaa gcactgctca gaaatcaaaa
      661 aagggtaaga gaaacttttt taaagcacag ctttatacaa caaacacagt aaagactgat
      721 ttgcctccac cctcctctga aagcgagcaa atagatttga ctgaggaaca gaaggatgac
      781 tcagaatggt taagcagcga tgtgatttgc atcgatgatg gccccattgc tgaagtgcat
      841 ataaatgaag atgctcagga aagtgactct ctgaaaactc atttggaaga tgaaagagat
      901 aatagcgaaa agaagaagaa tttggaagaa gctgaattac attcaactga gaaagttcca
      961 tgtattgaat ttgatgatga tgattatgat acggattttg ttccaccttc tccagaagaa
     1021 attatttctg cttcttcttc ctcttcaaaa tgccttagta cgttaaagga ccttgacacc
     1081 tctgacagaa aagaggatgt tcttagcaca tcaaaagatc ttttgtcaaa acctgagaaa
     1141 atgagtatgc aggagctgaa tccagaaacc agcacagact gtgacgctag acagataagt
     1201 ttacagcagc agcttattca tgtgatggag cacatctgta aattaattga tactattcct
     1261 gatgataaac tgaaactttt ggattgtggg aacgaactgc ttcagcagcg gaacataaga
     1321 aggaaacttc taacggaagt agattttaat aaaagtgatg ccagtcttct tggctcattg
     1381 tggagataca ggcctgattc acttgatggc cctatggagg gtgattcctg ccctacaggg
     1441 aattctatga aggagttaaa tttttcacac cttccctcaa attctgtttc tcctggggac
     1501 tgtttactga ctaccaccct aggaaagaca ggattctctg ccaccaggaa gaatcttttt
     1561 gaaaggcctt tattcaatac ccatttacag aagtcctttg taagtagcaa ctgggctgaa
     1621 acaccaagac taggaaaaaa aaatgaaagc tcttatttcc caggaaatgt tctcacaagc
     1681 actgctgtga aagatcagaa taaacatact gcttcaataa atgacttaga aagagaaacc
     1741 caaccttcct atgatattga taattttgac atagatgact ttgatgatga tgatgactgg
     1801 gaagacataa tgcataattt agcagccagc aaatcttcca cagctgccta tcaacccatc
     1861 aaggaaggtc ggccaattaa atcagtatca gaaagacttt cctcagccaa gacagactgt
     1921 cttccagtgt catctactgc tcaaaatata aacttctcag agtcaattca gaattatact
     1981 gacaagtcag cacaaaattt agcatccaga aatctgaaac atgagcgttt ccaaagtctt
     2041 agttttcctc atacaaagga aatgatgaag atttttcata aaaaatttgg cctgcataat
     2101 tttagaacta atcagctaga ggcgatcaat gctgcactgc ttggtgaaga ctgttttatc
     2161 ctgatgccga ctggaggtgg taagagtttg tgttaccagc tccctgcctg tgtttctcct
     2221 ggggtcactg ttgtcatttc tcccttgaga tcacttatcg tagatcaagt ccaaaagctg
     2281 acttccttgg atattccagc tacatatctg acaggtgata agactgactc agaagctaca
     2341 aatatttacc tccagttatc aaaaaaagac ccaatcataa aacttctata tgtcactcca
     2401 gaaaagatct gtgcaagtaa cagactcatt tctactctgg agaatctcta tgagaggaag
     2461 ctcttggcac gttttgttat tgatgaagca cattgtgtca gtcagtgggg acatgatttt
     2521 cgtcaagatt acaaaagaat gaatatgctt cgccagaagt ttccttctgt tccggtgatg
     2581 gctcttacgg ccacagctaa tcccagggta cagaaggaca tcctgactca gctgaagatt
     2641 ctcagacctc aggtaattgt acaaccatcc ccaatatcta agtttacagc atttttatca
     2701 ccccagcgag aaacctggta cccattagca gctgctccgc atcttctccc tcttgtttgt
     2761 gcccggcttc tttcactgag cgtagttttc aagggtcatc catgttgtag cattggtcag
     2821 taagtacttc attcattttt ata
//
