LOCUS       NM_001204425            5137 bp    mRNA    linear   PRI 17-APR-2022
DEFINITION  Homo sapiens BIVM-ERCC5 readthrough (BIVM-ERCC5), mRNA.
ACCESSION   NM_001204425
VERSION     NM_001204425.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5137)
  AUTHORS   Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y,
            Fujikake T, Takeda T and Taylor TD.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS ONE 5 (10), e13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL157769.12 and LM994822.1.
            
            On Jan 4, 2020 this sequence version replaced NM_001204425.1.
            
            Summary: This locus represents naturally occurring read-through
            transcription between the neighboring BIVM (basic,
            immunoglobulin-like variable motif containing) and ERCC5 (excision
            repair cross-complementing rodent repair deficiency,
            complementation group 5) genes on chromosome 13. The read-through
            transcript encodes a fusion protein that shares sequence identity
            with the products of each individual gene. [provided by RefSeq, Feb
            2011].
            
            ##Evidence-Data-START##
            Transcript exon combination :: LM994822.1, AB209312.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 2073, 54841
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               AL157769.12        91865-91986
            123-5045            LM994822.1         1-4923
            5046-5137           AL157769.12        160623-160714
FEATURES             Location/Qualifiers
     source          1..5137
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q33.1"
     gene            1..5137
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /note="BIVM-ERCC5 readthrough"
                     /db_xref="GeneID:100533467"
                     /db_xref="HGNC:HGNC:43690"
     exon            1..600
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..5045
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /codon_start=1
                     /product="BIVM-ERCC5 protein"
                     /protein_id="NP_001191354.2"
                     /db_xref="GeneID:100533467"
                     /db_xref="HGNC:HGNC:43690"
                     /translation="MPNVAETERSNDSGNGEHKSERKSPEENLQGAVKSFCTSASGAP
                     LGPKGDGHYPWSCPVTHTREKIYAICSDYAFLNQATSIYKTPNPSRSPCLPDSTSLSA
                     GNNSSRYIGIPTSTSEIIYNEENSLENLSNSLGKLPLAWEIDKSEFDGVTTNSKHKSG
                     NAKKQVSKRKTSDKKGRYQKECPQHSPLEDIKQRKVLDLRRWYCISRPQYKTSCGISS
                     LISCWNFLYSTMGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQIND
                     HFHVKGCSYVLYKPHGKNKTAGETASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFE
                     ATPVKANKAFSRGPLSPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDI
                     RHLERGLQYRKTKKVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAK
                     SESEDNISKKQHGRLGRSFSASFHQDSAWKKMSNISIWLNQALKGVRDRHGNSIENPH
                     LLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKT
                     FLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMN
                     QKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDD
                     FSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDT
                     SHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRT
                     LLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVK
                     VCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVAS
                     TNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPN
                     GRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASE
                     VIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISI
                     PKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGE
                     APAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSL
                     KAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTIT
                     DDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGI
                     PTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT
                     PGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLK
                     QLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVA
                     MEKEFELLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKGKNTCGGFLGETCLSESSD
                     GSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGG
                     KEKMVLVTARSVFGKKRRKLRRARGRKRKT"
     exon            601..727
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            728..823
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            824..928
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1023
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1156
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1243
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1340
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1572
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1748
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1864
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..1951
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            1952..2012
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            2013..2156
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2364
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..3438
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            3439..3683
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            3684..3803
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            3804..4017
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            4018..4162
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            4163..4363
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            4364..4448
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     exon            4449..5137
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5113..5118
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /note="hexamer: AATAAA"
     polyA_site      5137
                     /gene="BIVM-ERCC5"
                     /gene_synonym="ERCC5-202"
                     /note="major polyA site"
ORIGIN      
        1 gagctcattt tgcagctctc aagcttttat agcatgctgt aaacaattgt caaagttgtt
       61 tatcaagaaa cagatagagt tgcaacttgt ttctagtaat agaaactttt acactgcatt
      121 caatgcctaa cgttgcagaa acagaaaggt caaatgattc tggaaatggt gagcacaaat
      181 ctgagagaaa gtcacctgaa gagaatctac aaggtgctgt aaaatctttc tgcacaagtg
      241 cctcaggagc acccttgggt cccaaaggag atggtcatta tccatggagt tgtccagtga
      301 ctcatacacg ggaaaaaatt tatgccatct gttcggacta tgcctttctc aaccaggcga
      361 cctcaatcta taaaactcca aatccatccc gctctccttg cctccctgat agtacctctt
      421 tatctgctgg aaataattca tcaagataca ttggtatccc gactagtaca tcggaaatta
      481 tctacaatga agaaaatagc ttggaaaact tatccaacag cctgggcaag ctacctctcg
      541 catgggaaat tgataaatct gaatttgatg gggtgaccac aaattcgaaa cacaaatcag
      601 gcaatgcaaa gaaacaagtt tccaagagaa aaacttcaga taaaaaggga agatatcaga
      661 aggaatgtcc tcagcattct cctcttgaag atattaaaca gcggaaagta ttagacctca
      721 gacgatggta ctgcataagc cgaccacagt ataagacttc ttgtggcatc tcttcattaa
      781 tttcttgttg gaatttctta tacagcacaa tgggagctgg aaaccttcca cctattaccc
      841 aagaagaagc tttacatatt ctgggctttc aacctccatt tgaagatatt aggtttggtc
      901 ctttcacggg gaatacaaca cttatgaggt ggtttagaca aattaatgac cacttccatg
      961 taaaaggatg ctcttatgtt ctatataagc ctcatgggaa gaataaaaca gcaggagaaa
     1021 ctgcttcagg ggccctgtca aagttaaccc gtggattgaa agatgaatcg ctggcttata
     1081 tctatcattg ccaaaatcat tatttttgtc caattggctt cgaagcaacc cctgttaaag
     1141 ctaataaagc attcagcagg ggacctctct caccacagga agttgaatat tggatcttaa
     1201 ttggagaatc aagtagaaaa catcctgcca ttcactgtaa aaaatgggca gatattgtta
     1261 ctgatctaaa cactcaaaat ccagaatacc tggatatccg gcacttagag aggggactgc
     1321 agtatagaaa aacaaagaag gttgggggaa atttgcattg catcatagca ttccagagac
     1381 ttaactggca aagatttggc ctttggaact ttccatttgg aaccattaga caagaatcac
     1441 aacctccaac acatgcccag ggaattgcca aatctgagag tgaagacaat atttccaaga
     1501 agcagcatgg gcgtctgggc cggtctttca gtgctagttt ccatcaggac tcggcatgga
     1561 aaaagatgtc taatattagc atttggttaa accaagcact taaaggagtc cgggatcgcc
     1621 atgggaactc aatagaaaat cctcatcttc tcactttgtt tcatcggctc tgcaaactct
     1681 tattttttcg aattcgtcct atttttgtgt ttgatgggga tgctccacta ttgaagaaac
     1741 agactttggt gaagagaagg cagagaaagg acttagcgtc cagtgactcc aggaaaacga
     1801 cagagaagct tctgaaaaca tttttgaaaa gacaagccat caaaactgcc ttcagaagca
     1861 aaagagatga agcactaccc agtcttaccc aagttcgaag agaaaacgac ctctatgttt
     1921 tgcctccttt acaagaggaa gaaaaacaca gttcagaaga ggaagatgaa aaagaatggc
     1981 aagaaagaat gaatcaaaaa caagcattac aggaagagtt ctttcataat cctcaagcga
     2041 tagatattga gtctgaggac ttcagcagcc tgccccctga agtaaagcat gaaatcttga
     2101 ctgatatgaa agagttcacc aagcgcagaa gaacattatt tgaagcaatg ccagaggagt
     2161 ctgatgactt ttcacagtac caactcaaag gcttgcttaa aaagaactat ctgaaccagc
     2221 atatagaaca tgtccaaaag gaaatgaatc agcaacattc aggacacatc cgaaggcagt
     2281 atgaagatga agggggcttt ctgaaggagg tagagtcaag gagagtggtc tctgaagaca
     2341 cttcacatta catcttgata aaaggtattc aagctaagac agttgcagaa gtggattcag
     2401 agtctcttcc ttcttccagc aaaatgcacg gcatgtcttt tgacgtgaag tcatctccat
     2461 gtgaaaaact gaagacagag aaagagcctg atgctacccc tccttctcca agaactttac
     2521 tagctatgca agctgccctg ctgggaagta gctcagaaga ggagctggag agtgaaaatc
     2581 gaaggcaggc ccgtgggagg aacgcacctg ctgctgtaga cgaaggctcc atatcacccc
     2641 ggactctttc agccattaag agagctcttg acgatgacga agatgtaaaa gtgtgtgctg
     2701 gggatgatgt gcagacggga gggccaggag cagaagaaat gcgtataaac agctccaccg
     2761 agaacagtga tgaaggactt aaagtgagag atggaaaagg aataccgttt actgcaacac
     2821 ttgcgtcatc tagtgtgaac tctgcagagg agcacgtagc cagcactaat gaggggagag
     2881 agcccacaga ctcagttcca aaagaacaaa tgtcacttgt tcacgtgggg actgaagcct
     2941 ttccgataag tgatgagtct atgattaagg acagaaaaga tcggctgcct ctggagagtg
     3001 cagtggttag acatagtgac gcacctgggc tcccgaatgg aagggaactg acaccggcat
     3061 ctccaacttg tacaaattct gtgtcaaaga atgaaacaca tgctgaagtg cttgagcagc
     3121 agaacgaact ttgcccatat gagagtaaat tcgattcttc tcttctttca agtgatgatg
     3181 aaacaaaatg taaaccgaat tctgcttctg aagtcattgg ccctgtcagt ttgcaagaaa
     3241 caagtagcat agtaagtgtc ccttcagagg cagtagataa tgtggaaaat gtggtgtcat
     3301 ttaatgctaa agagcatgag aattttctgg aaaccatcca agaacagcag accactgaat
     3361 ctgcaggcca ggatttaatt tccattccaa aggccgtgga accaatggaa attgactcgg
     3421 aagaaagtga atctgatgga agtttcattg aagtgcaaag tgtgattagt gatgaggaac
     3481 ttcaagcaga attccctgaa acttccaaac ctccctcaga acaaggcgaa gaggaactgg
     3541 taggaactag ggagggagaa gcccctgctg agtccgagag cctcctgagg gacaactctg
     3601 agagggacga cgtggatggt gagccacagg aagctgagaa agatgcggaa gattcgctcc
     3661 atgaatggca agatattaat ttggaggagt tggaaactct ggagagcaac ctcttagcac
     3721 agcagaattc actgaaagct caaaaacagc agcaagaacg gatcgctgct actgtcaccg
     3781 gacagatgtt cctggaaagc caggaactcc tgcgcctgtt cggcattccc tacatccagg
     3841 ctcccatgga agcagaggcg cagtgcgcca tcctggacct gactgatcag acttccggaa
     3901 ccatcactga tgacagtgat atctggctgt ttggagcgcg gcatgtctat agaaactttt
     3961 ttaataaaaa caagtttgta gaatattatc aatatgtgga ctttcacaat caattgggat
     4021 tggaccggaa taagttaata aatttggctt atttgcttgg aagtgattat accgaaggaa
     4081 taccaactgt gggttgtgta accgccatgg aaattctcaa tgaattccct gggcatggcc
     4141 tggaacctct cctaaaattc tcagaatggt ggcatgaagc tcaaaaaaat ccaaagataa
     4201 gacctaatcc tcatgacacc aaagtgaaaa aaaaattacg gacattgcaa ctcacccctg
     4261 gctttcctaa cccagctgtt gccgaggcct acctcaaacc cgtggtggat gactcgaagg
     4321 gatcctttct gtgggggaaa cctgatctcg acaaaattag agaattttgt cagcggtatt
     4381 tcggctggaa cagaacgaag acagatgaat ctctgtttcc tgtattaaag caactcgatg
     4441 cccagcagac acagctccga attgattcct tctttagatt agcacaacag gagaaagaag
     4501 atgctaaacg tattaagagc cagagactaa acagagctgt gacatgtatg ctaaggaaag
     4561 agaaagaagc agcagccagc gaaatagaag cagtttctgt tgccatggag aaagaatttg
     4621 agctacttga taaggcaaaa ggaaaaaccc agaagagagg cataacaaat accttagaag
     4681 agtcatcaag cctgaaaaga aagaggcttt cagattctaa aggaaagaat acatgcggtg
     4741 gatttttggg ggagacctgc ctctcagaat catctgatgg atcttcaagt gaagatgctg
     4801 aaagttcatc tttaatgaat gtacaaagga gaacagctgc gaaagagcca aaaaccagtg
     4861 cttcagattc gcagaactca gtgaaggaag ctcccgtgaa gaatggaggt gcgaccacca
     4921 gcagctctag tgatagtgat gacgatggag ggaaagagaa gatggtcctc gtgaccgcca
     4981 gatctgtgtt tgggaagaaa agaaggaaac taagacgtgc gaggggaaga aaaaggaaaa
     5041 cctaattaaa aaatatgtat cctctataat tagttatgac agccatttgt aatgaatttg
     5101 tcgcaaagac gtaataaaat taactggtgg cacggtc
//
