LOCUS       NM_001394372            5687 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens BRD4 interacting chromatin remodeling complex
            associated protein (BICRA), transcript variant 2, mRNA.
ACCESSION   NM_001394372 XM_005258833
VERSION     NM_001394372.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5687)
  AUTHORS   Asadauskaite,G., Morkuniene,A., Utkus,A. and Burnyte,B.
  TITLE     Identification of a novel BICRA variant leading to the newly
            described Coffin-Siris syndrome 12
  JOURNAL   Brain Dev 45 (3), 185-190 (2023)
   PUBMED   36437209
  REMARK    GeneRIF: Identification of a novel BICRA variant leading to the
            newly described Coffin-Siris syndrome 12.
REFERENCE   2  (bases 1 to 5687)
  AUTHORS   Han,F., Yang,B., Zhou,M., Huang,Q., Mai,M., Huang,Z., Lai,M., Xu,E.
            and Zhang,H.
  TITLE     GLTSCR1 coordinates alternative splicing and transcription
            elongation of ZO1 to regulate colorectal cancer progression
  JOURNAL   J Mol Cell Biol 14 (2) (2022)
   PUBMED   35218185
  REMARK    GeneRIF: GLTSCR1 coordinates alternative splicing and transcription
            elongation of ZO1 to regulate colorectal cancer progression.
REFERENCE   3  (bases 1 to 5687)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   4  (bases 1 to 5687)
  AUTHORS   Barish,S., Barakat,T.S., Michel,B.C., Mashtalir,N., Phillips,J.B.,
            Valencia,A.M., Ugur,B., Wegner,J., Scott,T.M., Bostwick,B.,
            Murdock,D.R., Dai,H., Perenthaler,E., Nikoncuk,A., van
            Slegtenhorst,M., Brooks,A.S., Keren,B., Nava,C., Mignot,C.,
            Douglas,J., Rodan,L., Nowak,C., Ellard,S., Stals,K., Lynch,S.A.,
            Faoucher,M., Lesca,G., Edery,P., Engleman,K.L., Zhou,D.,
            Thiffault,I., Herriges,J., Gass,J., Louie,R.J., Stolerman,E.,
            Washington,C., Vetrini,F., Otsubo,A., Pratt,V.M., Conboy,E.,
            Treat,K., Shannon,N., Camacho,J., Wakeling,E., Yuan,B., Chen,C.A.,
            Rosenfeld,J.A., Westerfield,M., Wangler,M., Yamamoto,S., Kadoch,C.,
            Scott,D.A. and Bellen,H.J.
  CONSRTM   Undiagnosed Diseases Network
  TITLE     BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder
            Related Phenotypes in Humans and Model Organisms
  JOURNAL   Am J Hum Genet 107 (6), 1096-1112 (2020)
   PUBMED   33232675
  REMARK    GeneRIF: BICRA, a SWI/SNF Complex Member, Is Associated with
            BAF-Disorder Related Phenotypes in Humans and Model Organisms.
REFERENCE   5  (bases 1 to 5687)
  AUTHORS   Gatchalian,J., Malik,S., Ho,J., Lee,D.S., Kelso,T.W.R.,
            Shokhirev,M.N., Dixon,J.R. and Hargreaves,D.C.
  TITLE     A non-canonical BRD9-containing BAF chromatin remodeling complex
            regulates naive pluripotency in mouse embryonic stem cells
  JOURNAL   Nat Commun 9 (1), 5139 (2018)
   PUBMED   30510198
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5687)
  AUTHORS   Rajaraman,P., Hutchinson,A., Wichner,S., Black,P.M., Fine,H.A.,
            Loeffler,J.S., Selker,R.G., Shapiro,W.R., Rothman,N., Linet,M.S.
            and Inskip,P.D.
  TITLE     DNA repair gene polymorphisms and risk of adult meningioma, glioma,
            and acoustic neuroma
  JOURNAL   Neuro Oncol 12 (1), 37-48 (2010)
   PUBMED   20150366
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 5687)
  AUTHORS   Wu,C., Ma,M.H., Brown,K.R., Geisler,M., Li,L., Tzeng,E., Jia,C.Y.,
            Jurisica,I. and Li,S.S.
  TITLE     Systematic identification of SH3 domain-mediated human
            protein-protein interactions by peptide array target screening
  JOURNAL   Proteomics 7 (11), 1775-1785 (2007)
   PUBMED   17474147
REFERENCE   8  (bases 1 to 5687)
  AUTHORS   Yang,P., Kollmeyer,T.M., Buckner,K., Bamlet,W., Ballman,K.V. and
            Jenkins,R.B.
  TITLE     Polymorphisms in GLTSCR1 and ERCC2 are associated with the
            development of oligodendrogliomas
  JOURNAL   Cancer 103 (11), 2363-2372 (2005)
   PUBMED   15834925
  REMARK    GeneRIF: Polymorphisms in GLTSCR1 are associated with the
            development of oligodendrogliomas.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   9  (bases 1 to 5687)
  AUTHORS   Rockenbauer,E., Bendixen,M.H., Bukowy,Z., Yin,J., Jacobsen,N.R.,
            Hedayati,M., Vogel,U., Grossman,L., Bolund,L. and Nexo,B.A.
  TITLE     Association of chromosome 19q13.2-3 haplotypes with basal cell
            carcinoma: tentative delineation of an involved region using data
            for single nucleotide polymorphisms in two cohorts
  JOURNAL   Carcinogenesis 23 (7), 1149-1153 (2002)
   PUBMED   12117772
REFERENCE   10 (bases 1 to 5687)
  AUTHORS   Smith,J.S., Tachibana,I., Pohl,U., Lee,H.K., Thanarajasingam,U.,
            Portier,B.P., Ueki,K., Ramaswamy,S., Billings,S.J.,
            Mohrenweiser,H.W., Louis,D.N. and Jenkins,R.B.
  TITLE     A transcript map of the chromosome 19q-arm glioma tumor suppressor
            region
  JOURNAL   Genomics 64 (1), 44-50 (2000)
   PUBMED   10708517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010331.8, AC008985.7 and AC010519.8.
            
            On Apr 15, 2021 this sequence version replaced XM_005258833.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038192.1870930.1,
                                           SRR14038195.1547445.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000594866.3/ ENSP00000469738.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                AC010331.8         86892-86926
            36-137              AC008985.7         33997-34098
            138-183             AC008985.7         37124-37169
            184-226             AC008985.7         37274-37316
            227-292             AC008985.7         39405-39470
            293-2248            AC008985.7         42875-44830
            2249-2425           AC008985.7         45530-45706
            2426-3037           AC010519.8         17246-17857
            3038-3218           AC010519.8         18031-18211
            3219-3328           AC010519.8         18496-18605
            3329-3390           AC010519.8         19582-19643
            3391-3539           AC010519.8         21765-21913
            3540-3634           AC010519.8         22096-22190
            3635-3737           AC010519.8         22434-22536
            3738-5687           AC010519.8         24459-26408
FEATURES             Location/Qualifiers
     source          1..5687
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.33"
     gene            1..5687
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /note="BRD4 interacting chromatin remodeling complex
                     associated protein"
                     /db_xref="GeneID:29998"
                     /db_xref="HGNC:HGNC:4332"
                     /db_xref="MIM:605690"
     exon            1..35
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            36..137
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            138..183
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..4825
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /note="glioma tumor suppressor candidate region gene 1
                     protein; BRD4 interacting chromatin remodelling complex
                     associated protein"
                     /codon_start=1
                     /product="BRD4-interacting chromatin-remodeling
                     complex-associated protein"
                     /protein_id="NP_001381301.1"
                     /db_xref="CCDS:CCDS46134.1"
                     /db_xref="GeneID:29998"
                     /db_xref="HGNC:HGNC:4332"
                     /db_xref="MIM:605690"
                     /translation="MDDEDGRCLLDVICDPQALNDFLHGSEKLDSDDLLDNPGEAQSA
                     FYEGPGLHVQEASGNHLNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCD
                     ILQQSLQEANITEQTLEAEAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALF
                     PGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLP
                     NGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLA
                     SAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSS
                     PLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPK
                     APQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVH
                     LLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQ
                     LIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSL
                     PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPA
                     PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP
                     PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA
                     KGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTR
                     PPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPG
                     PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ
                     GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIIL
                     QNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL
                     LPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHL
                     HKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLK
                     RTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSS
                     SRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWA
                     RASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSK
                     VVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGT
                     APHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVE
                     DELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQD
                     DTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGG
                     LGARTLTR"
     exon            184..226
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            227..292
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            293..2248
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2425
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            2426..3037
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            3038..3218
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            3219..3328
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            3329..3390
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            3391..3539
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            3540..3634
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            3635..3737
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     exon            3738..5687
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5657..5662
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /note="hexamer: ATTAAA"
     polyA_site      5687
                     /gene="BICRA"
                     /gene_synonym="CSS12; GLTSCR1; SMARCK1"
                     /note="major polyA site"
ORIGIN      
        1 ggagaccccg cgccgacggc tgctcaaaca tcaggctggc ccccaagagg accctttcca
       61 agtccccagc tgggggccct gtgtagacct ggagtggaca cgcccctcct tcccttcatg
      121 attcgtttgt agcgcagtgg cgatggatga tgaggatggg agatgcttac tagacgtgat
      181 ttgtgaccca caggccctca atgacttctt gcatggatcc gagaagcttg acagtgatga
      241 cctcctggat aatcccgggg aggcccaaag tgccttctat gaaggtcctg ggctccatgt
      301 gcaagaagct tccggcaacc acctgaaccc agagcccaac cagccggccc ccagtgtgga
      361 cctagacttc ctggaagatg acatcctggg ctctcctgcg acagggggcg gcggcggggg
      421 cagtgggggc gctgaccagc cctgtgacat cctccagcag agcctccaag aggccaacat
      481 cacggagcag acgctggagg ccgaggctga gctggacctg ggtcccttcc agctgcccac
      541 cctgcagcct gcggatggcg gggcaggccc gacgggcgct ggaggggcag cggccgtggc
      601 tgcggggccc caagccctct tcccaggcag caccgacctg ctggggctgc agggcccgcc
      661 taccgtgctg acccaccagg ccctggtgcc gccccaggac gtggtcaaca aggccctgag
      721 tgtgcagccc ttcctgcagc ctgtgggcct gggcaatgtg acactgcagc ccatcccggg
      781 cctccaaggc ctgcccaatg gcagccctgg gggtgccacg gcggccacac tgggcctggc
      841 gcccatccag gtggtgggcc agcccgtcat ggcgctcaac acgcccacct cccagctcct
      901 ggccaagcag gtgcccgtca gcggctacct ggcctcggcg gctggcccct cggagcccgt
      961 gacgctggcg tcggccggtg tctcgccaca gggggctggc ctggtcatcc agaagaacct
     1021 ctcggccgct gtggccacca cgctcaatgg gaactctgtg ttcggaggcg cgggggccgc
     1081 ctcggctccc accgggacgc cctcgggaca gccgctggcg gtggccccag gcctcggctc
     1141 gtcgccactg gtcccggcgc ccaacgtgat cctgcatcgc acacccacgc ccatccagcc
     1201 caagcccgcg ggggtgctgc cgcccaagct ctaccagctg acgcccaagc cgtttgcgcc
     1261 cgcgggcgcc acgctcacca tccagggcga gccgggggcg ctcccgcagc agcccaaggc
     1321 cccgcagaac ctgacgttca tggcggcggg gaaggcgggc cagaacgtgg tgctgtcggg
     1381 cttccccgcg cctgcgctgc aagcgaacgt cttcaagcag ccaccggcca ccaccaccgg
     1441 agcggccccg ccgcagcccc ccggggccct gagcaaaccc atgagcgtcc acctcctgaa
     1501 ccaaggcagc agcatcgtca tccccgccca gcacatgctg ccgggccaga accagttcct
     1561 actgcctggc gccccggcgg tccagctccc gcagcagctc tcagccctgc cggccaacgt
     1621 gggcgggcag atcctggcgg ccgctgcccc ccacacaggt ggacagctca tcgcgaaccc
     1681 catcctcaca aaccagaacc tggcgggccc actgagcctg ggccccgtgt tggcccccca
     1741 ctccggggcc cacagcgcgc acatcctctc cgccgctccc atccaggtgg gccagcctgc
     1801 gctcttccag atgcccgtgt cgctggcggc gggcagcctg cccacgcaga gccagccagc
     1861 gcccgccggg ccggccgcca ccactgtcct ccagggggtc accctgcccc ccagcgccgt
     1921 ggccatgctc aacacccccg acggcctggt gcagccggcc acccctgccg ctgccaccgg
     1981 ggaggccgcg cctgtcctca cggtgcagcc tgccccccag gcgccccccg cggtcagcac
     2041 acccctgccc ctgggcctcc agcagccgca ggcgcagcag cccccgcagg cccccacccc
     2101 acaggccgcc gccccgcctc aggccaccac cccccagccc agccctggcc tggcgtctag
     2161 cccggagaag atcgtcctgg ggcagccgcc ctctgccacc cccacggcca tcctcactca
     2221 ggactccctg cagatgttcc tgccccagga gaggagccag cagcccctct ccgcagaggg
     2281 cccccacctc tccgtgcctg cctcggtcat agtcagcgcc ccgcctcccg cccaagaccc
     2341 agccccagcc acccccgtcg ccaaaggagc tggcctcggc cctcaggccc ccgacagcca
     2401 ggcttccccg gctccggccc cccagatccc ggcagcggct ccgctgaagg gcccaggccc
     2461 ctcttcgtcc ccgtcactac ctcaccaggc ccctctgggg gacagccccc acctgccctc
     2521 cccacacccc acccggcccc cttcccgccc accctcccgg ccacagagtg tgtcccgccc
     2581 tccctcagag ccacccttgc acccttgccc cccaccccag gcccccccaa ctctgcctgg
     2641 catctttgtc atccaaaacc agctaggcgt tcccccgcct gccagcaacc cggcccctac
     2701 tgccccaggc ccgccgcagc cgcctctccg cccccagtcc cagccgcctg agggaccgct
     2761 gcccccagcc ccccacctcc ctccatcctc cacctcctct gctgtggcct cctcctctga
     2821 gacgtcctcc aggttgccag cccctacgcc atccgacttc cagctccagt tcccacccag
     2881 ccaggggccc cacaagtccc ccactccccc tccaaccctc cacctggtcc ctgagccggc
     2941 agcacccccc ccaccgcctc ctcggacctt ccagatggtg accaccccct tcccagcgct
     3001 gccccagccg aaggctcttc tcgagagatt tcaccaggtg ccgtccggaa tcatcctcca
     3061 gaacaaggct gggggggccc ctgccgcccc gcagacctcc accagcctgg ggcccctcac
     3121 cagccccgct gcgtctgtgc tggtcagtgg gcaggcccca tctgggaccc ccactgcccc
     3181 cagccacgcc cccgccccgg cacccatggc cgccacaggc ctccctcctc tgcttccagc
     3241 cgagaacaag gcttttgcca gcaacctccc gaccctgaat gtggccaagg ccgcttcctc
     3301 cgggccaggg aagccctccg ggctgcagta tgagagcaaa ctgagtggcc tgaagaagcc
     3361 ccccacgctt cagcccagca aggaagcctg tttcctggag catttgcaca aacaccaggg
     3421 ctccgtcctg caccccgact acaagacggc cttcccctcc tttgaggacg ccctgcatcg
     3481 cctcctgccc taccatgtct accagggcgc cctcccctcc cccagtgact accacaaagt
     3541 ggacgaggag tttgagacgg tctccacgca gctgctgaaa cgcacccagg ccatgctcaa
     3601 taaatatcgg ctcctgctcc tggaggagtc ccggagggtg agcccctcag cggagatggt
     3661 aatgatcgac cgaatgttca ttcaggagga gaagaccacc cttgccttgg ataaacagct
     3721 ggccaaggag aagccggacg agtacgtgtc ttcctcccgc tcgctcggcc tccccatcgc
     3781 agcctcttcc gagggtcatc ggcttcccgg ccacggcccc ctgtcgtctt cagctcccgg
     3841 ggcctccacc cagccccctc cacacctgcc caccaagctt gtgatccggc acggcggggc
     3901 aggcggctcc ccttcggtca cctgggcccg ggcgtcctcc tccctgtcct cctcttcctc
     3961 ctcctcctct gccgcctcct ccttggacgc cgacgaggac ggccccatgc cctcccgcaa
     4021 ccgcccgccc atcaagacct acgaggcccg gagccgcatc gggctcaagc tcaagatcaa
     4081 gcaggaagcc gggctcagca aggtcgtgca caacacggcc ctggaccccg tgcaccagcc
     4141 cccgccaccc cccgctaccc tcaaggtggc cgagcccccg ccacggccgc caccaccacc
     4201 gccgcccacg ggccagatga acggcacggt ggaccacccg ccgcctgccg cccccgagcg
     4261 caagcccctg ggcaccgccc cgcactgccc gcgcctgcca ctgcgcaaga cctaccgcga
     4321 gaacgtgggg ggccctggcg cgccggaggg gacgcccgca ggcagggcac ggggaggcag
     4381 cccggcgccg ctgcccgcca aagtggacga ggccaccagc gggctcatcc gcgagctggc
     4441 ggccgtggag gacgagctgt accagcgtat gctgaagggc cccccgccag agcccgcagc
     4501 cagcgccgcc caaggcaccg gggaccccga ctgggaggcg cccgggctgc cccctgccaa
     4561 gcggcgcaag tccgagtcgc ccgacgtgga ccaggccagc ttctccagcg acagcccgca
     4621 ggatgacacg ctcaccgagc acctgcagag cgccatcgac agcatcctga acctgcagca
     4681 ggcccccggc cggacgcccg cgccctcgta cccccacgct gcctcggccg gcacccccgc
     4741 atccccgccg cccctgcaca ggcccgaggc ctacccaccc tccagtcaca acggtggcct
     4801 cggcgccagg acgttgacca gataacaccg ggccgcctcc ccttccccgt cccctcctcc
     4861 cgaagacgcc gggacagtcg ggtgtccgcc ctcagcctcc tggggactcg agccggggat
     4921 cccctgacgg tttttcttgc ctaagttatt tgagtcacaa aggcctcctt ccctgccgcc
     4981 tgcttcagct gggttgctgg ggggtgggcg tggatttagg gagggggctg tgatgtaaaa
     5041 cgtctcccct gccaaaggag gggcaaagtg ctgtgtcagt tcctgtttct tcccatttcc
     5101 tggcacactc tgcccctctg tccgggggac acgcgcatgt gtttgccagg gatggggcca
     5161 ccgggttgat gccaacgctc cgggtgcctg tcttgtctgt gtggcttctc agatggtgga
     5221 gggtgctggg agctggcagg gtccttccag acagtctcag cctctccccg ccgcccccaa
     5281 caggctgtca aacaaaaccg gagagggggt gggggagcca gcctcccagc gtgctgtgcc
     5341 cgcaggcacc cgtgtgacat ccgcacgtcc agctccgtga cctgtgtgtg tgtgtgtgtg
     5401 cacaagtgag tgagagattt cgaacgccca cccctcgact ttgaaatctg agcaaaacaa
     5461 gaaactgggg tcttcctctc ccccgaacct ctccccagct agtcttccct ctgttcttcc
     5521 tgcctccagc cgcccgcgcc agattttgaa atctcggaga caaaactagt actgtaagat
     5581 aaattttttt gtactgtatt tattgtgtat aacgattttt ttaaaggaga attctgtaca
     5641 tttagaactc ttgtaaatta aaaaccgatc ctttttttaa aactgta
//
