LOCUS       NM_001367886            3832 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens BICD family like cargo adaptor 1 (BICDL1), transcript
            variant 5, mRNA.
ACCESSION   NM_001367886 XM_005253991
VERSION     NM_001367886.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3832)
  AUTHORS   Hoogenraad,C.C. and Akhmanova,A.
  TITLE     Bicaudal D Family of Motor Adaptors: Linking Dynein Motility to
            Cargo Binding
  JOURNAL   Trends Cell Biol 26 (5), 327-340 (2016)
   PUBMED   26822037
  REMARK    Review article
REFERENCE   2  (bases 1 to 3832)
  AUTHORS   Schlager,M.A., Kapitein,L.C., Grigoriev,I., Burzynski,G.M.,
            Wulf,P.S., Keijzer,N., de Graaff,E., Fukuda,M., Shepherd,I.T.,
            Akhmanova,A. and Hoogenraad,C.C.
  TITLE     Pericentrosomal targeting of Rab6 secretory vesicles by
            Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis
  JOURNAL   EMBO J 29 (10), 1637-1651 (2010)
   PUBMED   20360680
REFERENCE   3  (bases 1 to 3832)
  AUTHORS   Need,A.C., Attix,D.K., McEvoy,J.M., Cirulli,E.T., Linney,K.L.,
            Hunt,P., Ge,D., Heinzen,E.L., Maia,J.M., Shianna,K.V., Weale,M.E.,
            Cherkas,L.F., Clement,G., Spector,T.D., Gibson,G. and
            Goldstein,D.B.
  TITLE     A genome-wide study of common SNPs and CNVs in cognitive
            performance in the CANTAB
  JOURNAL   Hum Mol Genet 18 (23), 4650-4661 (2009)
   PUBMED   19734545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC004815.2 and AC004812.1.
            
            On Dec 22, 2018 this sequence version replaced XM_005253991.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1965299,
                              SAMEA1966682 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000548673.6/ ENSP00000447477.2
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1062              AC004815.2         55626-56687
            1063-1278           AC004815.2         64911-65126
            1279-1395           AC004812.1         7762-7878
            1396-1542           AC004812.1         10785-10931
            1543-1722           AC004812.1         17674-17853
            1723-1941           AC004812.1         18563-18781
            1942-2085           AC004812.1         20495-20638
            2086-2216           AC004812.1         26939-27069
            2217-2337           AC004812.1         36003-36123
            2338-3832           AC004812.1         39052-40546
FEATURES             Location/Qualifiers
     source          1..3832
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.23"
     gene            1..3832
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /note="BICD family like cargo adaptor 1"
                     /db_xref="GeneID:92558"
                     /db_xref="HGNC:HGNC:28095"
                     /db_xref="MIM:617002"
     exon            1..1062
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             634..2499
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /note="isoform 2 is encoded by transcript variant 5;
                     coiled-coil domain-containing protein 64A; coiled-coil
                     domain containing 64; bicaudal D-related protein 1;
                     BICD-related protein 1; BICD family-like cargo adapter 1"
                     /codon_start=1
                     /product="BICD family-like cargo adapter 1 isoform 2"
                     /protein_id="NP_001354815.1"
                     /db_xref="CCDS:CCDS91757.1"
                     /db_xref="GeneID:92558"
                     /db_xref="HGNC:HGNC:28095"
                     /db_xref="MIM:617002"
                     /translation="MSAFCLGLVGRASAPAEPDSACCMELPAAAGDAVRSPAAAAALI
                     FPGGSGELELALEEELALLAAGERPSDPGEHPQAEPGSLAEGAGPQPPPSQDPELLSV
                     IRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENRE
                     GEWEGRVSELESDVKQLQDELERQQIHLREADREKSRAVQELSEQNQRLLDQLSRASE
                     VERQLSMQVHALREDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEEN
                     DLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSCRQLQVKVEELTEERSL
                     QSSAATSTSLLSEIEQSMEAEELEQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAV
                     STDSSMDESSETSSAKDVPAGSLRTALNELKRLIQSIVDGMEPTGSRRLDDDSLEEQI
                     RQTSEDSRALRELMEGERGKLRQSLEELQRLHSQVTLLSVEMTALKEERDRLRVTSED
                     KEPKEQLQKAIRDRDEAIAKKNAVELELAKCRMDMMSLNSQLLDAIQQKLNLSQQLEA
                     WQDDMHRVIDRQLMDTHLKERSQPAAALCRGHSAGRGDEPSIAEGKRLFSFFRKI"
     exon            1063..1278
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1395
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1542
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1722
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1941
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1942..2085
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2216
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2337
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2338..3832
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3812..3817
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /note="hexamer: AATAAA"
     polyA_site      3832
                     /gene="BICDL1"
                     /gene_synonym="BICDR-1; BICDR1; CCDC64; CCDC64A;
                     H_267D11.1"
                     /note="major polyA site"
ORIGIN      
        1 aggaaggagc tcgccgggtt gcgcggcgcg cgatgtggag ccgccgcctc ggcccctgca
       61 gcagcagcag ccgccgtcgc cgccgctgct gctggggctg ccgcggagcc gggggtcatg
      121 gagtgcggct gcagagagcg gccgccggca acagcagcag cagcaggaag cgtcgcggcg
      181 acagcggagc gcagcccgcc ccgtgaggcg ctgcccggcc ggcggcggca gcagcagcag
      241 cagcggcagc ggcaacaggg cggctgagaa cccggcggcg gcgttcctcc tcgcttcctc
      301 ccctcccgct tcgccgaccc tcagtctctg ttcctgagtc ctcccttccc cagccttccc
      361 gttcccacca cctactccgc cactaccccc accccctcct cccgcgcgcg cctgagcagc
      421 tgagcccggg ggcgggggag ggggcgcgtg ccgccggcgc gggggagggg cgggccggcg
      481 cgcgccgcgc ccagggctcg cggggacccg ggggcgcgtg ccgcggcgcg aggcgaggcg
      541 cgggacgcgg ggcggcgcgg cagggcccct cccccctgca gcctggcgcg cgcgggccgg
      601 gccgcaccgc tgcgggctcc gcgcgcgcgg gccatgtccg ctttctgcct gggcttggtc
      661 ggccgcgctt cagcacccgc cgagccggac agcgcctgct gcatggagct gcccgccgcg
      721 gccggggacg cagtccggag tcccgccgcc gccgccgccc tcatcttccc cgggggctcc
      781 ggggagctag aactggcgtt agaggaggag ctggcgctgc tggcggccgg ggagcggccg
      841 tccgaccccg gggaacaccc tcaggccgag cctgggtctc tggccgaggg ggccggaccg
      901 cagccgccgc cctcccagga ccccgagctg ctgtcggtga tccgacagaa ggagaaggat
      961 ctggtgttgg cggcccggct gggtaaggcg ctgctcgaga ggaaccagga catgagccgg
     1021 cagtacgagc agatgcataa ggagctgaca gacaagctcg agcacttaga gcaagagaaa
     1081 catgaattga gaagacgatt tgagaaccga gaaggggagt gggaaggccg agtgtcagag
     1141 ctggagagtg atgtgaagca gctacaggat gagttggaga ggcagcagat tcatctgcgg
     1201 gaagcagatc gagaaaaatc acgggctgtc caggaactgt cggaacagaa ccaaaggcta
     1261 ttggatcagc tcagcagggc atcagaagtt gagagacaac tctccatgca ggtccacgcc
     1321 ctcagagaag actttcggga gaaaaactca tcaaccaacc agcacattat ccggctggag
     1381 agccttcagg ccgagatcaa gatgctgtca gatcggaaac gggagctgga gcatcgtctc
     1441 agcgctactt tagaggaaaa tgacctgctc caagggaccg tggaggagct acaggaccgg
     1501 gtgctaatcc tggagaggca gggccatgac aaggacctac agctgcacca aagccagctg
     1561 gagcttcagg aggtgcgtct ctcctgccga cagctgcagg tgaaggtgga agaactcact
     1621 gaggagagga gtctgcagag ctctgccgcc accagcacat ccctcctgtc agagatcgag
     1681 cagagcatgg aggctgagga gctggagcag gagcgagagc agctgagact gcagctctgg
     1741 gaagcctact gccaggttcg ctatctgtgc tcacaccttc gaggcaatga cagtgctgac
     1801 tcagccgtct ccacggactc ctccatggac gagtcttcag aaacctcgtc cgccaaggat
     1861 gtgccagccg gcagcttgcg cactgccctc aatgagctca agagactgat acagagcatt
     1921 gtggatggca tggagcccac gggctcccgg agacttgatg atgactcctt agaagaacag
     1981 ataaggcaga ccagtgagga ctcgagagcc ctaagggagc tcatggaggg agagaggggt
     2041 aaactgaggc aaagcctaga agagctgcag cgactccaca gtcaggtgac actgctgagt
     2101 gtggagatga ctgccctaaa agaggagaga gaccgactca gagtcacttc tgaggacaag
     2161 gagccaaagg agcagcttca gaaggccatc agggaccgcg acgaggccat tgcaaagaag
     2221 aatgctgtgg agctggaact tgccaagtgc aggatggata tgatgtctct gaacagccag
     2281 ttgctggatg ccattcagca gaaactgaac ctctcgcagc agctggaagc ttggcaggat
     2341 gacatgcaca gggtcattga ccggcagctg atggacacgc acctgaaaga acggagccag
     2401 ccggctgctg ccctctgcag gggccacagc gctgggcggg gggatgagcc cagcatcgct
     2461 gaaggcaaac gactcttctc attcttcagg aaaatttaag ttgggaggag tcaggccacc
     2521 aaagatgggt ggactggagg cagctggaaa ggcggtgcag gcaaggcctc ccctgcagct
     2581 tgcacctcag cagctgccct gcccctcatg ctagggcccc atgggtccgg gagggcctgc
     2641 tccctttcgt cggtggggat ggagacctag aggtgggggc ctgccttggc cactgaaggc
     2701 ttcccttggc ccaccgcctg gccaagccca cgcctgggct tctccaggac cacgtgcttg
     2761 agcagggtta ggccacctcc cagaggggcc ccttggtgtt gggctttgca gctcacaccc
     2821 aacagatcgc agcccacccc caggcactgc tgcctccttg attttagcaa atggggaaca
     2881 gaaggaatgg aggcccttct ctgcatgcct caggaggcct gagccccagg ggcctagacc
     2941 tgtgggggca gcgggccagg cctgagcctc cattccttcc ccagcccctg gcccagggtc
     3001 aaaggagaga tggcagcccc tcccccgcat gcatgcacct cagctggcag gaggccaagc
     3061 ctctggccgc agggtctaag agccggggct tacccaagct cagctgaggc cacccgagcc
     3121 ccagggagga agaaggccct gtccccctgt cgccactgct ctccctccca gccttcagtc
     3181 tctgcccctt agcagggcct ggccaggcag agtgttatca ccagtcatct gcaggcttta
     3241 gccatccagc cctttcccct gctcagggct ggggttggac ggggtctcct cctcccacag
     3301 ctccctcctc cacccctcac atacatacat aatttcttgg cctagccaaa caagtccagg
     3361 ccactgaatg gcaccagagg ggtctgtggt cagccacccc accttgaggg cagcacaggc
     3421 accacggggt ggaggggagg gggaggctgc cggaagcctc cagatgctgc ctgcctgcct
     3481 gcagaagcct gcagtggctg ctgctcctgc ctctgcagcc gcccctcctc ctccacccag
     3541 gccccaactc agaggctccg cggcccggcc agccctcagc tgctcacaac cgattcagtc
     3601 tccctccctc cctcacgtgg ggaaagcaca gcagggatgc gcggcaagaa tgtacctgta
     3661 gatgtgtaca taccacagtg ctgtaatttt gtatgtagca atcatgtaaa tacatgtatg
     3721 gattttataa tatacatata taaaaatcta taaaggcata tttttagaaa aacagcacac
     3781 cactgcttct tttgaaaata gtctgaataa gaataaaatg aatttctaca ga
//
