LOCUS       NM_022893               6102 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens BCL11 transcription factor A (BCL11A), transcript
            variant 1, mRNA.
ACCESSION   NM_022893
VERSION     NM_022893.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6102)
  AUTHORS   Taleb Brahim,A., Taleb,M., Soumare,H., Ghaber,S.M., Mohamed,A. and
            Ould Mohamed Salem Boukhary,A.
  TITLE     Genotyping the BCL11A Single Nucleotide Polymorphism and Associated
            Levels of Fetal Hemoglobin in Mauritanian Sickle Cell Patients
  JOURNAL   Front Biosci (Schol Ed) 16 (2), 11 (2024)
   PUBMED   38939975
  REMARK    GeneRIF: Genotyping the BCL11A Single Nucleotide Polymorphism and
            Associated Levels of Fetal Hemoglobin in Mauritanian Sickle Cell
            Patients.
REFERENCE   2  (bases 1 to 6102)
  AUTHORS   Huang,P., Peslak,S.A., Shehu,V., Keller,C.A., Giardine,B., Shi,J.,
            Hardison,R.C., Blobel,G.A. and Khandros,E.
  TITLE     let-7 miRNAs repress HIC2 to regulate BCL11A transcription and
            hemoglobin switching
  JOURNAL   Blood 143 (19), 1980-1991 (2024)
   PUBMED   38364109
  REMARK    GeneRIF: let-7 miRNAs repress HIC2 to regulate BCL11A transcription
            and hemoglobin switching.
REFERENCE   3  (bases 1 to 6102)
  AUTHORS   Finotti,A., Gasparello,J., Zuccato,C., Cosenza,L.C., Fabbri,E.,
            Bianchi,N. and Gambari,R.
  TITLE     Effects of Mithramycin on BCL11A Gene Expression and on the
            Interaction of the BCL11A Transcriptional Complex to gamma-Globin
            Gene Promoter Sequences
  JOURNAL   Genes (Basel) 14 (10), 1927 (2023)
   PUBMED   37895276
  REMARK    GeneRIF: Effects of Mithramycin on BCL11A Gene Expression and on
            the Interaction of the BCL11A Transcriptional Complex to
            gamma-Globin Gene Promoter Sequences.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6102)
  AUTHORS   Yin,J., Xie,X., Quan,Y., Wang,Z., Liu,S., Su,Q., Che,F. and Wang,L.
  TITLE     RNA-seq analysis reveals candidate genes associated with
            proliferation, invasion, and migration in BCL11A knockdown B-NHL
            cell lines
  JOURNAL   Ann Hematol 102 (7), 1845-1856 (2023)
   PUBMED   37148312
  REMARK    GeneRIF: RNA-seq analysis reveals candidate genes associated with
            proliferation, invasion, and migration in BCL11A knockdown B-NHL
            cell lines.
REFERENCE   5  (bases 1 to 6102)
  AUTHORS   Liu,A., Hu,Y., Chong,B., Zheng,S. and Li,L.
  TITLE     [Genetic analysis of a family with BCL11A-related intellectual
            disability]
  JOURNAL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 40 (1), 42-46 (2023)
   PUBMED   36584999
  REMARK    GeneRIF: [Genetic analysis of a family with BCL11A-related
            intellectual disability].
REFERENCE   6  (bases 1 to 6102)
  AUTHORS   Satterwhite,E., Sonoki,T., Willis,T.G., Harder,L., Nowak,R.,
            Arriola,E.L., Liu,H., Price,H.P., Gesk,S., Steinemann,D.,
            Schlegelberger,B., Oscier,D.G., Siebert,R., Tucker,P.W. and
            Dyer,M.J.
  TITLE     The BCL11 gene family: involvement of BCL11A in lymphoid
            malignancies
  JOURNAL   Blood 98 (12), 3413-3420 (2001)
   PUBMED   11719382
REFERENCE   7  (bases 1 to 6102)
  AUTHORS   Saiki,Y., Yamazaki,Y., Yoshida,M., Katoh,O. and Nakamura,T.
  TITLE     Human EVI9, a homologue of the mouse myeloid leukemia gene, is
            expressed in the hematopoietic progenitors and down-regulated
            during myeloid differentiation of HL60 cells
  JOURNAL   Genomics 70 (3), 387-391 (2000)
   PUBMED   11161790
REFERENCE   8  (bases 1 to 6102)
  AUTHORS   Nakamura,T., Yamazaki,Y., Saiki,Y., Moriyama,M., Largaespada,D.A.,
            Jenkins,N.A. and Copeland,N.G.
  TITLE     Evi9 encodes a novel zinc finger protein that physically interacts
            with BCL6, a known human B-cell proto-oncogene product
  JOURNAL   Mol Cell Biol 20 (9), 3178-3186 (2000)
   PUBMED   10757802
REFERENCE   9  (bases 1 to 6102)
  AUTHORS   Avram,D., Fields,A., Pretty On Top,K., Nevrivy,D.J., Ishmael,J.E.
            and Leid,M.
  TITLE     Isolation of a novel family of C(2)H(2) zinc finger proteins
            implicated in transcriptional repression mediated by chicken
            ovalbumin upstream promoter transcription factor (COUP-TF) orphan
            nuclear receptors
  JOURNAL   J Biol Chem 275 (14), 10315-10322 (2000)
   PUBMED   10744719
REFERENCE   10 (bases 1 to 6102)
  AUTHORS   Peron,A., Bradbury,K., Viskochil,D.H. and Dias,C.
  TITLE     BCL11A-Related Intellectual Disability
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   31556984
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC009970.10, AJ404611.1,
            AB058712.1, AF080216.1, AK001035.1 and BG393787.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_022893.3.
            
            Summary: This gene encodes a C2H2 type zinc-finger protein by its
            similarity to the mouse Bcl11a/Evi9 protein. The corresponding
            mouse gene is a common site of retroviral integration in myeloid
            leukemia, and may function as a leukemia disease gene, in part,
            through its interaction with BCL6. During hematopoietic cell
            differentiation, this gene is down-regulated. It is possibly
            involved in lymphoma pathogenesis since translocations associated
            with B-cell malignancies also deregulates its expression. Multiple
            transcript variants encoding several different isoforms have been
            found for this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) is also known as B-cell
            lymphoma/leukaemia 11A extra long form (BCL11A-XL). It encodes the
            longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ404611.1, SRR6380202.108948.17
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2154665 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            coronavirus related    :: locus in the vicinity of
                                      disease-associated variant(s)
            MANE Ensembl match     :: ENST00000642384.2/ ENSP00000496168.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               AC009970.10        81045-81200         c
            157-707             AJ404611.1         1-551
            708-2471            AB058712.1         452-2215
            2472-2614           AF080216.1         2396-2538
            2615-3125           AK001035.1         328-838
            3126-6097           AJ404611.1         2970-5941
            6098-6102           BG393787.1         184-188
FEATURES             Location/Qualifiers
     source          1..6102
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p16.1"
     gene            1..6102
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /note="BCL11 transcription factor A"
                     /db_xref="GeneID:53335"
                     /db_xref="HGNC:HGNC:13221"
                     /db_xref="MIM:606557"
     exon            1..439
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /inference="alignment:Splign:2.1.0"
     CDS             385..2892
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ecotropic viral integration site 9 homolog; C2H2-type zinc
                     finger protein; B-cell lymphoma/leukemia 11A; B-cell
                     CLL/lymphoma 11A (zinc finger protein); BCL11A B-cell
                     CLL/lymphoma 11A (zinc finger protein);
                     COUP-TF-interacting protein 1; ecotropic viral integration
                     site 9 protein homolog; zinc finger protein 856; B cell
                     CLL/lymphoma 11A; BCL11A, BAF complex component; BAF
                     chromatin remodeling complex subunit BCL11A"
                     /codon_start=1
                     /product="B-cell lymphoma/leukemia 11A isoform 1"
                     /protein_id="NP_075044.2"
                     /db_xref="CCDS:CCDS1862.1"
                     /db_xref="GeneID:53335"
                     /db_xref="HGNC:HGNC:13221"
                     /db_xref="MIM:606557"
                     /translation="MSRRKQGKPQHLSKREFSPEPLEAILTDDEPDHGPLGAPEGDHD
                     LLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKAVDKPPSPSPIEMKKASNPVEVG
                     IQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRGLSSPRSAHGALIPTPGMSAEYAPQ
                     GICKDEPSSYTCTTCKQPFTSAWFLLQHAQNTHGLRIYLESEHGSPLTPRVGIPSGLG
                     AECPSQPPLHGIHIADNNPFNLLRIPGSVSREASGLAEGRFPPTPPLFSPPPRHHLDP
                     HRIERLGAEEMALATHHPSAFDRVLRLNPMAMEPPAMDFSRRLRELAGNTSSPPLSPG
                     RPSPMQRLLQPFQPGSKPPFLATPPLPPLQSAPPPSQPPVKSKSCEFCGKTFKFQSNL
                     VVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTHMHKSSPMTVKSDDGLSTASSPEP
                     GTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEEEEEEEEEEELTES
                     ERVDYGFGLSLEAARHHENSSRGAVVGVGDESRALPDVMQGMVLSSMQHFSEAFHQVL
                     GEKHKRGHLAEAEGHRDTCDEDSVAGESDRIDDGTVNGRGCSPGESASGGLSKKLLLG
                     SPSSLSPFSKRIKLEKEFDLPPAAMPNTENVYSQWLAGYAASRQLKDPFLSFGDSRQS
                     PFASSSEHSSENGSLRFSTPPGELDGGISGRSGTGSGGSTPHISGPGPGRPSSKEGRR
                     SDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKD
                     VYKCEICKMPFSVYSTLEKHMKKWHSDRVLNNDIKTE"
     exon            440..769
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /inference="alignment:Splign:2.1.0"
     exon            770..871
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /inference="alignment:Splign:2.1.0"
     exon            872..6102
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6082..6087
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /note="hexamer: AATAAA"
     polyA_site      6102
                     /gene="BCL11A"
                     /gene_synonym="CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1;
                     ZNF856"
                     /note="major polyA site"
ORIGIN      
        1 gtctctgtcc atccagactc ctgacgttca agttcgcagg gacgtcacgt ccgcacttga
       61 acttgcagct caggggggct tttgccattt ttttcatctc tctctctctc tctccctcta
      121 tctctcttct ctctctctcc ctcttttttt tttttttttt tttttttttt ttgcttaaaa
      181 aaaagccatg acggctctcc cacaattcat cttccctgcg ccatctttgt attatttcta
      241 atttattttg gatgtcaaaa ggcactgatg aagatatttt ctctggagtc tccttctttc
      301 taacccggct ctcccgatgt gaaccgagcc gtcgtccgcc cgccgccgcc gccgccgccg
      361 ccgccgcccg ccccgcagcc caccatgtct cgccgcaagc aaggcaaacc ccagcactta
      421 agcaaacggg aattctcgcc cgagcctctt gaagccattc ttacagatga tgaaccagac
      481 cacggcccgt tgggagctcc agaaggggat catgacctcc tcacctgtgg gcagtgccag
      541 atgaacttcc cattggggga cattcttatt tttatcgagc acaaacggaa acaatgcaat
      601 ggcagcctct gcttagaaaa agctgtggat aagccacctt ccccttcacc aatcgagatg
      661 aaaaaagcat ccaatcccgt ggaggttggc atccaggtca cgccagagga tgacgattgt
      721 ttatcaacgt catctagagg aatttgcccc aaacaggaac acatagcaga taaacttctg
      781 cactggaggg gcctctcctc ccctcgttct gcacatggag ctctaatccc cacgcctggg
      841 atgagtgcag aatatgcccc gcagggtatt tgtaaagatg agcccagcag ctacacatgt
      901 acaacttgca aacagccatt caccagtgca tggtttctct tgcaacacgc acagaacact
      961 catggattaa gaatctactt agaaagcgaa cacggaagtc ccctgacccc gcgggttggt
     1021 atcccttcag gactaggtgc agaatgtcct tcccagccac ctctccatgg gattcatatt
     1081 gcagacaata acccctttaa cctgctaaga ataccaggat cagtatcgag agaggcttcc
     1141 ggcctggcag aagggcgctt tccacccact ccccccctgt ttagtccacc accgagacat
     1201 cacttggacc cccaccgcat agagcgcctg ggggcggaag agatggccct ggccacccat
     1261 cacccgagtg cctttgacag ggtgctgcgg ttgaatccaa tggctatgga gcctcccgcc
     1321 atggatttct ctaggagact tagagagctg gcagggaaca cgtctagccc accgctgtcc
     1381 ccaggccggc ccagccctat gcaaaggtta ctgcaaccat tccagccagg tagcaagccg
     1441 cccttcctgg cgacgccccc cctccctcct ctgcaatccg cccctcctcc ctcccagccc
     1501 ccggtcaagt ccaagtcatg cgagttctgc ggcaagacgt tcaaatttca gagcaacctg
     1561 gtggtgcacc ggcgcagcca cacgggcgag aagccctaca agtgcaacct gtgcgaccac
     1621 gcgtgcaccc aggccagcaa gctgaagcgc cacatgaaga cgcacatgca caaatcgtcc
     1681 cccatgacgg tcaagtccga cgacggtctc tccaccgcca gctccccgga acccggcacc
     1741 agcgacttgg tgggcagcgc cagcagcgcg ctcaagtccg tggtggccaa gttcaagagc
     1801 gagaacgacc ccaacctgat cccggagaac ggggacgagg aggaagagga ggacgacgag
     1861 gaagaggaag aagaggagga agaggaggag gaggagctga cggagagcga gagggtggac
     1921 tacggcttcg ggctgagcct ggaggcggcg cgccaccacg agaacagctc gcggggcgcg
     1981 gtcgtgggcg tgggcgacga gagccgcgcc ctgcccgacg tcatgcaggg catggtgctc
     2041 agctccatgc agcacttcag cgaggccttc caccaggtcc tgggcgagaa gcataagcgc
     2101 ggccacctgg ccgaggccga gggccacagg gacacttgcg acgaagactc ggtggccggc
     2161 gagtcggacc gcatagacga tggcactgtt aatggccgcg gctgctcccc gggcgagtcg
     2221 gcctcggggg gcctgtccaa aaagctgctg ctgggcagcc ccagctcgct gagccccttc
     2281 tctaagcgca tcaagctcga gaaggagttc gacctgcccc cggccgcgat gcccaacacg
     2341 gagaacgtgt actcgcagtg gctcgccggc tacgcggcct ccaggcagct caaagatccc
     2401 ttccttagct tcggagactc cagacaatcg ccttttgcct cctcgtcgga gcactcctcg
     2461 gagaacggga gtttgcgctt ctccacaccg cccggggagc tggacggagg gatctcgggg
     2521 cgcagcggca cgggaagtgg agggagcacg ccccatatta gtggtccggg cccgggcagg
     2581 cccagctcaa aagagggcag acgcagcgac acttgtgagt actgtgggaa agtcttcaag
     2641 aactgtagca atctcactgt ccacaggaga agccacacgg gcgaaaggcc ttataaatgc
     2701 gagctgtgca actatgcctg tgcccagagt agcaagctca ccaggcacat gaaaacgcat
     2761 ggccaggtgg ggaaggacgt ttacaaatgt gaaatttgta agatgccttt tagcgtgtac
     2821 agtaccctgg agaaacacat gaaaaaatgg cacagtgatc gagtgttgaa taatgatata
     2881 aaaactgaat agaggtatat taatacccct ccctcactcc cacctgacac cccctttttc
     2941 accactcccc ttccccatcg ccctccagcc ccactccctg taggattttt ttctagtccc
     3001 atgtgattta aacaaacaaa caaacaaaca gaagtaacga agctaagaat atgagagtgc
     3061 ttgtcaccag cacacctgtt ttttttcttt ttctttttct tttttctttt tccttttttt
     3121 tttttttcct ttatgttctc accgtttgaa tgcatgatct gtatggggca atactattgc
     3181 attttacgca aactttgagc ctttctcttg tgcaataatt tacatgttgt gtatgttttt
     3241 ttttaaactt agacagcatg tatggtatgt tatggctatt ttaaattgtc cctaattcgt
     3301 tgctgagcaa acatgttgct gtttccagtt ccgttctgag agaaaaagag agagagagag
     3361 aaaaagacca tgctgcatac attctgtaat acatatcatg tacagtttta ttttataacg
     3421 tgaggaggaa aaacagtctt tggattaacc ctctatagac agaatagata gcactgaaaa
     3481 aaaatctcta tgagctaaat gtctgtctct aaagggttaa atgtatcaat tggaaaggaa
     3541 gaaaaaaggc cttgaattga caaattaaca gaaaaacaga acaagtttat tctatcattt
     3601 ggttttaaaa tatgagtgcc ttggatctat taaaaccaca tcgatggttc tttctacttg
     3661 ttataaactt gtagcttaat tcagcattgg gtgaggtaat aaaccttagg aactagcata
     3721 taattctata ttgtatttct cacaacaatg gctacctaaa aagatgaccc attatgtcct
     3781 agttaatcat catttttcct ttagtttaat tttataaaca aaactgatta taccagtata
     3841 aaagctactt tgctcctggt gagagcttaa aagaaatggg ctgttttgcc caaagtttta
     3901 ttttttttaa acaatgatta aattgaatgt gtaatgtgca aaagccctgg aacgcaatta
     3961 aatacactag taaggagttc attttatgaa gatatttgct ttaataatgt ctttttaaaa
     4021 atactggcac caaaagaaat agatccagat ctacttggtt gtcaagtgga caatcaaatg
     4081 ataaacttta agaccttgta taccatattg aaaggaagag gctgacaata aggtttgaca
     4141 gaggggaaca gaagaaaata atatgattta ttagcacaac gtggtactat ttgccattta
     4201 aaactagaac aggtatataa gctaatattg atacaatgat gattaactat gaattcttaa
     4261 gacttgcatt taaatgtgac attcttaaaa aaagaagaga aagaatttta agagtagcag
     4321 tatatatgtc tgtgctccct aaaagttgta cttcatttct tttccataca ctgtgtgcta
     4381 tttgtgttaa catggaagag gattcattgt ttttattttt atttttttaa ttttttcttt
     4441 tttattaagc tagcatctgc cccagttggt gttcaaatag cacttgactc tgcctgtgat
     4501 atctgtatct tttctctaat cagagataca gaggttgagt ataaaataaa cctgctcaga
     4561 taggacaatt aagtgcactg tacaattttc ccagtttaca ggtctatact taagggaaaa
     4621 gttgcaagaa tgctgaaaaa aaattgaaca caatctcatt gaggagcatt ttttaaaaac
     4681 taaaaaaaaa aaaactttgc cagccattta cttgactatt gagcttactt acttggacgc
     4741 aacattgcaa gcgctgtgaa tggaaacaga atacacttaa catagaaatg aatgattgct
     4801 ttcgcttcta cagtgcaagg atttttttgt acaaaacttt tttaaatata aatgttaaga
     4861 aaaatttttt ttaaaaaaca cttcattatg tttagggggg aactgcattt tagggttcca
     4921 ttgtcttggt ggtgttacaa gacttgttat ccatttaaaa atggtagtgg aaattctatg
     4981 ccttggatac acaccgctct tcaggttgta aaaaaaaaaa acatacattg gggaaaggtt
     5041 taagattata tagtacttaa atataggaaa atgcacactc atgttgattc ctatgctaaa
     5101 atacatttat ggtctttttt ctgtatttct agaatggtat ttgaattaaa tgttcatcta
     5161 gtgttaggca ctatagtatt tatattgaag cttgtatttt taactgttgc ttgttctctt
     5221 aaaaggtatc aatgtacctt ttttggtagt ggaaaaaaaa aagacaggct gccacagtat
     5281 atttttttaa tttggcagga taatatagtg caaattattt gtatgcttca aaaaaaaaaa
     5341 aaagagagaa acaaaaaagt gtgacattac agatgagaag ccatataatg gcggtttggg
     5401 ggagcctgct agaatgtcac atggatggct gtcatagggg ttgtacatat ccttttttgt
     5461 tcctttttcc tgctgccata ctgtatgcag tactgcaagc taataacgtt ggtttgttat
     5521 gtagtgtgct ttttgtccct ttccttctat caccctacat tccagcatct taccttcata
     5581 tgcagtaaaa gaaagaaaga aaaaaaaagg aaaaaaaaaa aaaaaccaat gttttgcagt
     5641 ttttttcatt gccaaaaact aaatggtgct ttatatttag attggaaaga atttcatatg
     5701 caaagcatat taaagagaaa gcccgcttta gtcaatactt ttttgtaaat ggcaatgcag
     5761 aatattttgt tattggcctt ttctattcct gtaatgaaag ctgtttgtcg taacttgaaa
     5821 ttttatcttt tactatggga gtcactattt attattgctt atgtgccctg ttcaaaacag
     5881 aggcacttaa tttgatcttt tatttttctt tgtttttatt ttttttttta tttagatgac
     5941 caaaggtcat tacaacctgg ctttttattg tatttgtttc tggtctttgt taagttctat
     6001 tggaaaaacc actgtctgtg tttttttggc agttgtctgc attaacctgt tcatacaccc
     6061 attttgtccc tttattgaaa aaataaaaaa aattaaagta ca
//
