LOCUS       NM_017679               3517 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens BCAS3 microtubule associated cell migration factor
            (BCAS3), transcript variant 2, mRNA.
ACCESSION   NM_017679
VERSION     NM_017679.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3517)
  AUTHORS   Wang,Y., Li,Y., Sun,Q., Yuan,F., Xu,Y., Tong,S., Li,Y., Yi,S.,
            Yan,T., Chen,Q. and Liu,B.
  TITLE     BCAS3 accelerates glioblastoma tumorigenesis by restraining the
            P53/GADD45alpha signaling pathway
  JOURNAL   Exp Cell Res 417 (2), 113231 (2022)
   PUBMED   35659972
  REMARK    GeneRIF: BCAS3 accelerates glioblastoma tumorigenesis by
            restraining the P53/GADD45alpha signaling pathway.
REFERENCE   2  (bases 1 to 3517)
  AUTHORS   Zhou,Z., Qiu,R., Liu,W., Yang,T., Li,G., Huang,W., Teng,X.,
            Yang,Y., Yu,H., Yang,Y. and Wang,Y.
  TITLE     BCAS3 exhibits oncogenic properties by promoting CRL4A-mediated
            ubiquitination of p53 in breast cancer
  JOURNAL   Cell Prolif 54 (8), e13088 (2021)
   PUBMED   34240781
  REMARK    GeneRIF: BCAS3 exhibits oncogenic properties by promoting
            CRL4A-mediated ubiquitination of p53 in breast cancer.
REFERENCE   3  (bases 1 to 3517)
  AUTHORS   Hengel,H., Hannan,S.B., Dyack,S., MacKay,S.B., Schatz,U.,
            Fleger,M., Kurringer,A., Balousha,G., Ghanim,Z., Alkuraya,F.S.,
            Alzaidan,H., Alsaif,H.S., Mitani,T., Bozdogan,S., Pehlivan,D.,
            Lupski,J.R., Gleeson,J.J., Dehghani,M., Mehrjardi,M.Y.V.,
            Sherr,E.H., Parks,K.C., Argilli,E., Begtrup,A., Galehdari,H.,
            Balousha,O., Shariati,G., Mazaheri,N., Malamiri,R.A.,
            Pagnamenta,A.T., Kingston,H., Banka,S., Jackson,A., Osmond,M.,
            Riess,A., Haack,T.B., Nagele,T., Schuster,S., Hauser,S., Admard,J.,
            Casadei,N., Velic,A., Macek,B., Ossowski,S., Houlden,H.,
            Maroofian,R. and Schols,L.
  CONSRTM   Care4Rare Canada Consortium; Genomics England Research Consortium
  TITLE     Bi-allelic loss-of-function variants in BCAS3 cause a syndromic
            neurodevelopmental disorder
  JOURNAL   Am J Hum Genet 108 (6), 1069-1082 (2021)
   PUBMED   34022130
  REMARK    GeneRIF: Bi-allelic loss-of-function variants in BCAS3 cause a
            syndromic neurodevelopmental disorder.
REFERENCE   4  (bases 1 to 3517)
  AUTHORS   Salamon,S., Bevc,S., Ekart,R., Hojs,R. and Potocnik,U.
  TITLE     Polymorphism in the GATM Locus Associated with Dialysis-Independent
            Chronic Kidney Disease but Not Dialysis-Dependent Kidney Failure
  JOURNAL   Genes (Basel) 12 (6), 834 (2021)
   PUBMED   34071541
  REMARK    GeneRIF: Polymorphism in the GATM Locus Associated with
            Dialysis-Independent Chronic Kidney Disease but Not
            Dialysis-Dependent Kidney Failure.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3517)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (bases 1 to 3517)
  AUTHORS   Siva,K., Venu,P., Mahadevan,A., S,K. S and Inamdar,M.S.
  TITLE     Human BCAS3 expression in embryonic stem cells and vascular
            precursors suggests a role in human embryogenesis and tumor
            angiogenesis
  JOURNAL   PLoS One 2 (11), e1202 (2007)
   PUBMED   18030336
  REMARK    GeneRIF: BCAS3 is mis-expressed in brain tumors and could serve as
            a human ES cell and tumor marker
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 3517)
  AUTHORS   Gururaj,A.E., Peng,S., Vadlamudi,R.K. and Kumar,R.
  TITLE     Estrogen induces expression of BCAS3, a novel estrogen
            receptor-alpha coactivator, through proline-, glutamic acid-, and
            leucine-rich protein-1 (PELP1)
  JOURNAL   Mol Endocrinol 21 (8), 1847-1860 (2007)
   PUBMED   17505058
  REMARK    GeneRIF: Physically associated with histone H3 and histone
            acetyltransferase complex protein P/CAF (p300/CBP-associated
            factor) and possesses histone acetyltransferase activity.
            Erratum:[Mol Endocrinol. 2013 May;27(5):862]
REFERENCE   8  (bases 1 to 3517)
  AUTHORS   Gururaj,A.E., Holm,C., Landberg,G. and Kumar,R.
  TITLE     Breast cancer-amplified sequence 3, a target of
            metastasis-associated protein 1, contributes to tamoxifen
            resistance in premenopausal patients with breast cancer
  JOURNAL   Cell Cycle 5 (13), 1407-1410 (2006)
   PUBMED   16855396
  REMARK    GeneRIF: BCAS3 overexpression in hormone receptor-positive
            premenopausal breast cancer seemed to be associated with impaired
            responses to tamoxifen
REFERENCE   9  (bases 1 to 3517)
  AUTHORS   Gururaj,A.E., Singh,R.R., Rayala,S.K., Holm,C., den Hollander,P.,
            Zhang,H., Balasenthil,S., Talukder,A.H., Landberg,G. and Kumar,R.
  TITLE     MTA1, a transcriptional activator of breast cancer amplified
            sequence 3
  JOURNAL   Proc Natl Acad Sci U S A 103 (17), 6670-6675 (2006)
   PUBMED   16617102
  REMARK    GeneRIF: role for MTA1-BCAS3 pathway in promoting cancerous
            phenotypes in breast tumor cells
            Erratum:[Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4147-8]
REFERENCE   10 (bases 1 to 3517)
  AUTHORS   Barlund,M., Monni,O., Weaver,J.D., Kauraniemi,P., Sauter,G.,
            Heiskanen,M., Kallioniemi,O.P. and Kallioniemi,A.
  TITLE     Cloning of BCAS3 (17q23) and BCAS4 (20q13) genes that undergo
            amplification, overexpression, and fusion in breast cancer
  JOURNAL   Genes Chromosomes Cancer 35 (4), 311-317 (2002)
   PUBMED   12378525
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110602.8, AC079005.9, AC015876.10, AC005884.1 and AC005746.1.
            
            On Jun 2, 2019 this sequence version replaced NM_017679.4.
            
            Transcript Variant: This variant (2) lacks alternate in-frame exons
            in the 3' coding region, compared to variant 3, resulting in a
            shorter protein (isoform 2), compared to isoform 3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF361219.1, SRR1803615.135538.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000407086.8/ ENSP00000385323.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                AC110602.8         82488-82551         c
            65-152              AC110602.8         80862-80949         c
            153-207             AC110602.8         76366-76420         c
            208-283             AC110602.8         70641-70716         c
            284-390             AC110602.8         51077-51183         c
            391-472             AC110602.8         13123-13204         c
            473-545             AC079005.9         96817-96889         c
            546-653             AC079005.9         36210-36317         c
            654-730             AC079005.9         30155-30231         c
            731-807             AC079005.9         15122-15198         c
            808-891             AC079005.9         2190-2273           c
            892-1062            AC015876.10        74064-74234         c
            1063-1156           AC015876.10        60266-60359         c
            1157-1290           AC015876.10        37414-37547         c
            1291-1555           AC005884.1         112430-112694       c
            1556-1706           AC005884.1         86764-86914         c
            1707-1831           AC005884.1         67875-67999         c
            1832-1997           AC005884.1         64611-64776         c
            1998-2098           AC005884.1         61773-61873         c
            2099-2199           AC005884.1         27645-27745         c
            2200-2396           AC005884.1         24136-24332         c
            2397-2494           AC005884.1         18101-18198         c
            2495-2662           AC005746.1         46438-46605         c
            2663-3517           AC005746.1         22101-22955         c
FEATURES             Location/Qualifiers
     source          1..3517
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q23.2"
     gene            1..3517
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /note="BCAS3 microtubule associated cell migration factor"
                     /db_xref="GeneID:54828"
                     /db_xref="HGNC:HGNC:14347"
                     /db_xref="MIM:607470"
     exon            1..64
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            65..152
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..2811
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /note="isoform 2 is encoded by transcript variant 2;
                     breast carcinoma-amplified sequence 3; metastasis
                     associated antigen of breast cancer; BCAS4/BCAS3 fusion;
                     breast carcinoma amplified sequence 4/3 fusion protein;
                     protein Maab1; Rudhira; phagophore assembly factor 2"
                     /codon_start=1
                     /product="BCAS3 microtubule associated cell migration
                     factor isoform 2"
                     /protein_id="NP_060149.3"
                     /db_xref="CCDS:CCDS11626.1"
                     /db_xref="GeneID:54828"
                     /db_xref="HGNC:HGNC:14347"
                     /db_xref="MIM:607470"
                     /translation="MNEAMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVV
                     PQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQ
                     VWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSIGSSGT
                     SPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFF
                     VTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTL
                     KSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLV
                     SEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQCA
                     VHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPR
                     VVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFT
                     NNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGTITKRTGKVKPPPQISPSKSMGGEFCV
                     AAIFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHMMEPRPLSTAPKIS
                     DDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLVPPGS
                     PGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQT
                     TVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRR
                     GVSTVIDAASGTFDRSVTLLEVCGSWPEGFGLRHMSSMEHTEEGLRERLADAMAESPS
                     RDVVGSGTELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNESQPLSLFPTGFP"
     exon            153..207
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            208..283
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            284..390
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            391..472
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            473..545
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            546..653
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            654..730
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            731..807
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            808..891
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1062
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1156
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1290
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1555
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1706
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1831
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..1997
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2098
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            2099..2199
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            2200..2396
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2494
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2662
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     exon            2663..3517
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3491..3496
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /note="hexamer: AATAAA"
     polyA_site      3517
                     /gene="BCAS3"
                     /gene_synonym="GAOB1; HEMARS; MAAB; PHAF2"
                     /note="major polyA site"
ORIGIN      
        1 actcggggag actccaaaca gtgagcctag agctggagac tagcgttaac cggcggggcg
       61 gccggtttta tgaatgaagc tatggctaca gattccccaa gaagacccag tcgttgtact
      121 ggtggagttg tggttcgccc ccaggctgtc acagagcagt cctacatgga aagtgttgtg
      181 acttttctgc aggatgttgt gccacaggct tacagtggaa cacctctaac agaagaaaag
      241 gagaaaatag tctgggtcag atttgaaaat gcagatttaa atgatacatc aagaaatctg
      301 gaatttcatg aaatacatag tactgggaat gaaccgcctt tgttgattat gattggctac
      361 agtgatggaa tgcaggtctg gagcatccct atcagtggtg aagcacaaga gctcttctct
      421 gttcgacatg gcccaattcg agcggctaga atcttgcctg ctccacagtt tggtgctcaa
      481 aaatgtgata actttgctga aaaaagaccc ctccttggtg tttgtaagag cattggatct
      541 tctggcacaa gcccaccgta ctgttgtgtg gatctgtatt cacttcgtac tggggagatg
      601 gtcaagtcca ttcaatttaa gacacctatt tatgatctcc attgcaataa acggatcctt
      661 gtcgtagtct tgcaggagaa aattgctgcc tttgatagct gtactttcac gaagaaattc
      721 tttgttacaa gctgctatcc atgtccaggg ccaaacatga atcctattgc tcttgggagc
      781 cgctggcttg cttatgcaga aaacaagttg attcgatgtc atcagtcccg tggtggagcc
      841 tgtggagaca acattcagtc ttatactgcc acagtcatta gtgctgctaa aacattgaaa
      901 agtggcctga caatggtagg gaaagtggtg actcagctga caggcacact gccttcaggt
      961 gtgacagaag atgatgttgc catccacagt aattcacggc ggagtccttt ggtcccaggc
     1021 atcatcacag ttattgacac cgaaaccgtt ggagagggcc aggtgcttgt gagtgaggat
     1081 tctgacagtg atggcattgt ggcccacttc cctgcccatg agaagccagt gtgctgcatg
     1141 gcttttaata caagtggaat gcttctagtc acaacagaca cccttggcca tgactttcat
     1201 gtcttccaaa ttctgactca tccttggtcc tcatcacaat gtgctgtcca ccatctgtat
     1261 actcttcaca ggggagaaac tgaagccaaa gtacaggaca tctgcttcag ccatgactgt
     1321 cgctgggttg tggtcagtac tctccggggt acttcccacg ttttccccat caacccttat
     1381 ggtggccagc cttgtgttcg tacacatatg tcaccacgag tagtgaatcg catgagccgt
     1441 ttccagaaaa gtgctggact ggaagagatt gaacaagaac tgacgtctaa gcaaggaggt
     1501 cgctgtagcc ctgttccagg tctatcaagc agcccttctg ggtcaccctt gcatgggaaa
     1561 ctgaacagcc aagactccta taacaatttt accaacaaca accctggcaa ccctcggctc
     1621 tctcctcttc ccagcttgat ggtagtgatg cctcttgcac aaatcaagca gccaatgaca
     1681 ttggggacca tcaccaaacg aaccggcaaa gttaaacctc ctccacaaat ttcacccagc
     1741 aaatcgatgg gcggagaatt ttgtgtggct gctatcttcg gaacatccag gtcatggttt
     1801 gcaaataatg caggtctgaa aagagaaaaa gatcagtcca aacaagttgt agttgagtcc
     1861 ctgtacatta tcagttgcta tggcacctta gtggaacaca tgatggagcc gcgacccctc
     1921 agcactgcac ccaagattag tgacgacaca ccactggaaa tgatgacatc gcctcgagcc
     1981 agctggactc tggttagaac ccctcaatgg aatgaattgc agccaccgtt taatgcaaac
     2041 caccctctgc tcctcgctgc agatgcagta cagtattatc agttcctgct tgctggcctg
     2101 gttccccctg gaagtcctgg gcccattact cgacatgggt cttacgacag tttagcttct
     2161 gaccatagtg gacaggaaga tgaagaatgg ctttcccagg ttgaaattgt aacacacact
     2221 ggaccccata gacgtctgtg gatgggtcca cagttccagt tcaaaaccat ccatccctca
     2281 ggccaaacca cagttatctc atccagttca tctgtgttgc agtctcatgg tccgagtgac
     2341 acgccacagc ctcttttgga ttttgataca gatgatcttg atctcaacag tctcaggatc
     2401 cagccagtcc gctctgaccc cgtcagcatg ccagggtcat cccgtccagt ctctgatcga
     2461 aggggagttt ccacagtgat tgatgctgcc tcaggtacct ttgacaggag cgtgaccctg
     2521 ctggaggtgt gcgggagctg gcctgagggc ttcgggctgc ggcacatgtc ctccatggag
     2581 cacacggagg agggcctccg ggagcgactt gccgacgcca tggccgagtc acctagccgg
     2641 gacgtcgtgg gatccggaac agaacttcag cgagagggaa gcatcgagac tctgagtaac
     2701 agctcaggct ccaccagcgg cagcatacca agaaactttg atggctaccg atctccgctg
     2761 cccaccaatg agagccagcc cctcagcctc ttcccgactg gcttcccgta ggtaccagca
     2821 acctgcttct gactggccag ccccctcccc tgctggagga ggggagaagc cccgctctgg
     2881 tcctaccctt cagtctctgc tcttccttca tcaaccacct tccccaagct tagtgacagc
     2941 agccgcccat cctacctgga tggagaagag acccttctcc aagcacctca gcgcacttgc
     3001 cctctgccac acctgtcggt ggaggctgtg gccaggagag actgtagaag ctcggtccct
     3061 gtgtatgttt gcatatgaca tcctgcattg gatccgcttt tgtatttttt aaccataccc
     3121 acggtggggc gggtgggggg agcctggaac agtgaccaga tctgggggcc tgagtgggga
     3181 cagagttgat cgtccacctg gccattttga ccctgagtgg acagtcacag cctcagctca
     3241 tgtctggctg tgacacacac tgcccccagc ttcccttggt cagccccact ccagcacggg
     3301 gtgaacggag gcccagagta ctagggaagg aggaagggag gacatgcctc ttcttcctcc
     3361 tttctttccc catctgttca tgggaagagt ttgtctttct tatctttaag cccctttacc
     3421 ctggtcctgt actgatcagt gaaggaaacc gtggttactg aggccctgtt gaaaagtgca
     3481 cgtcttgtcc aataaatcac gctgcagttg gtgtcca
//
