LOCUS       NM_001142568            9009 bp    mRNA    linear   PRI 14-MAR-2025
DEFINITION  Homo sapiens BBX high mobility group box domain containing (BBX),
            transcript variant 1, mRNA.
ACCESSION   NM_001142568
VERSION     NM_001142568.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9009)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 9009)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
REFERENCE   3  (bases 1 to 9009)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   4  (bases 1 to 9009)
  AUTHORS   Wang,H.Y., Peng,G., Guo,Z., Shevach,E.M. and Wang,R.F.
  TITLE     Recognition of a new ARTC1 peptide ligand uniquely expressed in
            tumor cells by antigen-specific CD4+ regulatory T cells
  JOURNAL   J Immunol 174 (5), 2661-2670 (2005)
   PUBMED   15728473
REFERENCE   5  (bases 1 to 9009)
  AUTHORS   Sanchez-Diaz,A., Blanco,M.A., Jones,N. and Moreno,S.
  TITLE     HBP2: a new mammalian protein that complements the fission yeast
            MBF transcription complex
  JOURNAL   Curr Genet 40 (2), 110-118 (2001)
   PUBMED   11680820
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA218136.1, AK291757.1, AC072044.9, AC117477.4, AI168295.1 and
            AW131333.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001142568.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK291757.1, SRR1803616.93608.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000325805.13/ ENSP00000319974.8
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                DA218136.1         27-54
            29-496              AK291757.1         1-468
            497-497             AC072044.9         53187-53187         c
            498-2368            AK291757.1         470-2340
            2369-2369           AC117477.4         9223-9223
            2370-3520           AK291757.1         2342-3492
            3521-8594           AC117477.4         36690-41763
            8595-8994           AI168295.1         7-406               c
            8995-8999           AW131333.1         26-30               c
            9000-9009           AC117477.4         42169-42178
FEATURES             Location/Qualifiers
     source          1..9009
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q13.12"
     gene            1..9009
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /note="BBX high mobility group box domain containing"
                     /db_xref="GeneID:56987"
                     /db_xref="HGNC:HGNC:14422"
                     /db_xref="MIM:621127"
     exon            1..146
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            147..218
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            219..292
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            293..463
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     CDS             302..3127
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /note="isoform 1 is encoded by transcript variant 1; x 001
                     protein; BBX, HMG-box containing; HMG box transcription
                     factor BBX; HMG box-containing protein 2; Ag recognized by
                     Treg cells 1; bobby sox homolog"
                     /codon_start=1
                     /product="HMG box transcription factor BBX isoform 1"
                     /protein_id="NP_001136040.1"
                     /db_xref="CCDS:CCDS46881.1"
                     /db_xref="GeneID:56987"
                     /db_xref="HGNC:HGNC:14422"
                     /db_xref="MIM:621127"
                     /translation="MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEE
                     EEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEH
                     PRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSP
                     TPTVNPRKKLWAFPSDSSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHA
                     LGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEI
                     SSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKLIKAKESDGGRIKELEKG
                     KEEKEIKMEKTDETRLQKEAEFEKSAKENLRDSKELRNFEALQIDDIMAIKMEDPKEI
                     RKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCHPHGIMIIEDPAALNKPEKL
                     KKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKLGDTPR
                     KKVRTSSSGKGSILDAKPPKKKVKSREKKMSKEKSSDTTKESRPPDFISISASKNISG
                     ETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIETCGSRKSERSCKGALYKTLV
                     SEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDC
                     LLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKKKTGNVSSEPTKTSKGPFQSQ
                     KKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAIHPTEAIFSEDRNTMEPVH
                     KVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTADGRVSPAGGTLDDKPKE
                     QLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLAALAEVAAMENVHRG
                     QRSTPLTHDGQPKEMPQAPVLISCADQ"
     exon            464..706
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            707..902
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            903..970
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1051
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1126
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1207
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..2216
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2355
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            2356..2504
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            2505..2594
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            2595..2654
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            2655..2852
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            2853..3039
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     exon            3040..9009
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8837..8842
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /note="hexamer: AATAAA"
     regulatory      8850..8855
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /note="hexamer: AATAAA"
     polyA_site      8864
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
     polyA_site      8873
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /note="major polyA site"
     regulatory      8885..8890
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /note="hexamer: AATATA"
     polyA_site      8909
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
     regulatory      8971..8976
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
                     /note="hexamer: AATAAA"
     polyA_site      9009
                     /gene="BBX"
                     /gene_synonym="ARTC1; HBP2; HSPC339; MDS001"
ORIGIN      
        1 gttgcatgta ctgtatgtgg agcagtgtac agtgaagcgg aggcagagcg gctccgcgag
       61 cttctctcca ctttcccata gagaaaccct gactggccgc tgagggctag ctacacacac
      121 gccctcacgc ccggcgagcc cgcgaggtca ctatcatatg acaaaggctt tgccgcagtt
      181 catcttcctc cctgtgtact ttccatttgc cttcctggaa tcctgctgca tcacagaagc
      241 tggaagttct gatgttccac tgaaatcaca atggaaagtc ttgacttgac tggtcacagt
      301 aatgaaaggc agtaatagaa ataaggatca ttcagcagaa ggagaagggg ttggaaaacg
      361 accaaaacga aagtgtcttc agtggcatcc attgctagca aagaaacttc ttgatttttc
      421 agaagaggaa gaagaggaag acgaagagga ggatattgat aaggttcaac ttcttggggc
      481 cgatggccta gagcaagatg ttggtgaaac tgaagatgat gaatcaccag agcagcgagc
      541 ccggagacca atgaatgcat ttcttttatt ttgcaaacgc catcgctctc ttgtacgtca
      601 ggaacacccc aggcttgata accgaggtgc taccaagata ctagctgatt ggtgggctgt
      661 tcttgatcca aaggaaaagc agaaatacac agacatggcc aaggagtata aggatgcatt
      721 tatgaaagca aatcctggct acaaatggtg tcctaccaca aacaagcctg tgaaatcccc
      781 aacacccact gtcaatccac gaaagaaact ttgggccttc ccatctgact cttcaagaga
      841 cttgccaagc cccaagaaag caaagactga agaaatgcct cagcttaact ttggaatggc
      901 tgatcctact caaatgggag gcctgagtat gctgctgtta gctggagaac atgctcttgg
      961 cacaccagag gtatcctctg gcacatgcag gcctgatgtt tcagaatctc ctgaattacg
     1021 tcagaagtca ccattgtttc agtttgccga gatatcttca agtacgtccc actctgatgc
     1081 ttctacaaag cagtgtcaaa catctgcctt gtttcagttt gcagagattt cttcaaacac
     1141 ttcgcagttg ggtggtgctg agcctgtaaa acgctgtgga aagtctgcac tctttcaact
     1201 ggcagagatg tgcctggcat cagaagggat gaaaatggaa gaatcaaagc taataaaagc
     1261 aaaagaatcc gatggtggaa gaattaaaga attagagaag ggaaaggaag aaaaagaaat
     1321 taaaatggag aaaacagatg aaactaggtt acagaaggaa gcagaatttg aaaaatcggc
     1381 taaggaaaat ttaagagatt ctaaggaatt gagaaatttt gaggcattgc aaatagatga
     1441 cataatggct ataaaaatgg aagatcccaa agaaattaga aaggaagagt tagaagaaga
     1501 tcacaaatgt agtcattttc ctgatttttc ttattctgcc agtagcaaga taataattag
     1561 tgatgttccc agtagaaagg atcatatgtg ccatcctcat ggaattatga tcattgagga
     1621 tcccgcagca ttaaacaagc cagaaaagct aaaaaagaaa aagaagaaaa gcaaaatgga
     1681 tcgacatgga aatgataaat ccacacccaa gaagacttgc aaaaagaggc agtcttcgga
     1741 atctgacatt gagagcgtca tatataccat tgaagccgtc gcaaaaggag actggggcat
     1801 agagaaactt ggagataccc ctcgcaagaa ggtccgcaca tcctcaagtg gcaagggaag
     1861 cattttggat gccaagccac caaagaaaaa agtgaaatca agagagaaga aaatgtcaaa
     1921 ggagaaatcc tcagacacca ccaaagagtc aagacctcca gatttcatta gtatttctgc
     1981 tagcaagaac atttctggtg agacaccaga gggtataaaa gcagaaccat tgacccctat
     2041 ggaagatgca ctaccaccca gcctatcagg acaggccaag cctgaggaca gtgactgtca
     2101 cagaaaaata gaaacttgtg gttccaggaa atccgagagg tcttgcaaag gtgctcttta
     2161 taaaaccctg gtgtctgagg gcatgctcac ctctctgcga gctaatgttg acagaggaaa
     2221 acgaagctca ggaaaaggaa actcctctga tcatgaaggg tgttggaatg aagaaagctg
     2281 gacatttagt cagagtggga ccagtgggag caagaagttc aagaagacaa agccaaaaga
     2341 agactgtctc cttggctccg caaagctgga tgaagaattt gaaaaaaaat tcaacagcct
     2401 ccctcaatat agtcctgtta catttgaccg gaaatgtgta cctgtcccaa gaaaaaagaa
     2461 gaagactgga aatgtgtcct cagaaccgac taaaaccagc aaaggtcctt tccagtctca
     2521 gaaaaagaac ttattccaca aaattgtcag caaatataag cacaaaaagg agaagcccaa
     2581 tgttccggaa aaaggaagtg gggataaatg gtcaaacaag caactcttct tggatgccat
     2641 tcaccctaca gaagccatat tttcagaaga cagaaacacc atggagcctg ttcataaggt
     2701 taaaaatatc ccatccattt tcaacactcc agagccaaca acaacgcaag aacctttggt
     2761 gggcagccaa aagagaaaag caaggaaaac caagattaca caccttgtca ggacagcaga
     2821 tggccgggta tcaccagcag gaggtacttt ggatgacaaa ccaaaggaac aactgcagag
     2881 gagtctccct aaagcaactg agacagactg caatgacaaa tgctcacaca acaccgaggt
     2941 cggggagacg cggagcagta ctccagaaat gcctgccgtg tctgcgttct ttagcctcgc
     3001 tgcgctggct gaagtggcag ccatggaaaa tgtgcacaga ggtcagaggt caactccgct
     3061 cacccatgat ggacagccaa aagaaatgcc gcaggctcct gtacttattt cctgcgctga
     3121 ccagtgaagc gccctttcat tgtaaaacat tgtgctttac ctactaccct agccttgtct
     3181 ttaccgaggg atgctagtga gtccaagtgg tggaaaatat agactgcaaa caagtgcttg
     3241 ttgccccaca cggcccagat tcacttgaag cagaagttag catcctgggc cagtttgttc
     3301 tctcagaacc cagaatcttt gagggtaagg ttatctgtct gatactgagc agaaacagaa
     3361 tgatcctgga gctttgcttt ctattgaagg cttttgacgg taataggtgg taacttggta
     3421 aaaggctgcc tttactgtag ctcacccagc atctctttta ccaaccagag agtgtgaaac
     3481 tagtttcata tattacctag ttattctttc aaaacaaaac aaaaaaaaaa caaaaactga
     3541 cgcactgcac tagttattat tagatattct tagtcttttt tgtacatgga gatttaagtt
     3601 taagatggtt tatataatag gttataccta catttatatt gtagaataaa tattaaaaag
     3661 cctgttccag agactcccaa gcagcctggg caggcagatg taccattgtt agtggtgtat
     3721 gctcggcctc gtggtccata tattctgcac ttttatattt gccaccagaa tggtagtttg
     3781 ctggcaaaaa aaaaaaaaaa agagagagag aaaaaattac aactcttaca atctgaattt
     3841 ttttcttagc cttgagtgac caagaagaat ttgcttgagg caaattgtgg caaatatttt
     3901 cccagacagg ggaagagtcc tgcagattac agattactgg tgttttcatg ccttgaggat
     3961 tcttttattt ttacataggg gtctaagtga ccaatggatt gttcatacaa acaaaaaaaa
     4021 agacaaaaat attattcaga agtgacctta gtattacttc actattctaa acacattgaa
     4081 gacactcact tcatgtggac ttggagctac agacctttta catccatcac agattggctg
     4141 gacgggttgc aattgctatg cacagcctga ttggcactgc aggtttttag agccattttg
     4201 agtttgtgtt gtttaggagg tactgagtca atgatgaggg aggtatgcct gaccagagtg
     4261 ggactctcag tcatagatcc acctgcaagt ctctgtttcc tttttgtgtt ttgttgcttt
     4321 tgaacataaa accaaccata cataagcagc gccaagtgga ttaactggct tagaacattc
     4381 aacatattga cttaaccacc tgacattcac agtgtcttgt ttcctagcaa cagatgcaaa
     4441 gtgataaatc aaaattagtc tgaggctaca gattttacag ggtatttgtt ctatagcaca
     4501 aagtatttcc ccactcttgc gtcacagcac aaactaccaa attttaatta ttggattcca
     4561 gcaataattt ttaatggttt tcaaactggc ggaattttga cagtgctagt tcgagtttga
     4621 agcttttgaa ttagatctct aaatggtgac agtttacatg gttttatcta gctttcttat
     4681 ttatacttga ctgaattgta atgatttttt ttctaattgt aatttgacgt aatagccata
     4741 caaaaaatga ctctattcat actaggttta gcttctcatg gttgtagata ttacttcagt
     4801 tccggtgctg gaaaatatgt acaacatact aacaggattg aaaaaaaaat agaggttttt
     4861 cttcttgttt ttttttccaa agcaggtaaa gagggtagca aagcatcgga atgatgtgct
     4921 caaaaatgca tattcctggt ggggatggag gaagaaggca ttagtaaaag gttaatcaaa
     4981 cgttacaact taaccccatt catgtaggaa taaatcaagt gagcagttcc agacttttgc
     5041 ataatatttt tactatgatg ctgttttatt aatattttct aaatttcaaa acaaaaagtg
     5101 aatgtttgaa attgctgggt cccgatgttg gtggctgttg gagttttgga ccactcgcta
     5161 gcagtgattt gaagattata attagctaaa atccaaaaca aaaaaccaac aacaaaaatt
     5221 gtatggtgcg gaacatgcac cttgacaatg gtactaactt gttattctat agaacacgtt
     5281 agaatagatc tatttttgcc agagcaccct ccttcagtcc tccgattaca tttcactaga
     5341 gttccttacg agattgctgt atattcctgg gacctttttt aaaaaaaaaa aaagcaaaac
     5401 aaaagattac tttttttcta tgtgattaat atcttacttg atctgctttt cctaaacctc
     5461 agtggctttt cccttaggca gggttggggg tgggagggca acttactgga gatgactgtt
     5521 ttcagatact ttaaaacaaa cctttttgta gaaatgctta atttttaagc ggttaggcac
     5581 tgagagtagc agaaatcctg caaagcttta tagttcctta gactcacctt gtcgattctc
     5641 tgagtaaagt cttgatttca ataattgtgc ttctcatgcc ctgaaactgc tggagaggag
     5701 tgttgttatt ttcaggtaac aacattcgtt agcacaaata tttcagacca atattagtgc
     5761 tctccacccc accttttgtt atcattttca tttcatttct ctcattcttt tttattttgg
     5821 aaaatcatat tgctatagtg tgtactttaa tctgccagca gataccatct acactaacat
     5881 ttgtcccaca gcatcctcaa gagaaaaagt tgttgcacct tatatatatc tcaagcaaac
     5941 caaaatatga tgctcttctg ctttgtttta ttctaaattg ttgtatcata tctttctgaa
     6001 accattctga atttagttga aattatcaat atttatgctt ttaaccttaa tttctggatt
     6061 caagcctgta tataaatctt ttgaaaaaaa attgtcctag cccttctctg cgatgctgga
     6121 agtagaagat tgcgtctcag atggagacgc agtactgttc cagttttctt tagcctttta
     6181 tttatttagt tattctgggt atttcctatg taattttgaa gtgtgtagag tatattatag
     6241 taactgaagc tgcagctgta agaagctgag tgaaagaaaa aatactgtaa gacatcctta
     6301 aagtttttat ttgtttgggt actgtatatg agatcaggaa aaagaaaaat gtcccacagc
     6361 cacattggaa atacaggttc ttgtccccaa attaggttag ttcccagatt ttagatcaaa
     6421 actgttaatt cattaaaacc ccttttaaaa ggtaaattct actgttgtaa ttccgatagt
     6481 ctttttccca caaatatcag aaatatattt atttaattct gtcagatgag ctttctaccg
     6541 atgccatgtc ccaaagccat gttaaaataa ttcccacgtt atcattgtga ttctacttcc
     6601 tgccactaaa attgctggag aaacaaaata atgatggaac actatgaaca aaaaggagca
     6661 tctgaactgg tctggttatt tagaatccaa tgtgttcaaa tccttttgtt ttcttattaa
     6721 gtcagatgct actgtaagtc agataaaatt ttgtttgcac tctgcagtct ttggctcaat
     6781 gtatggaaat gtttgcacct atgtaaagtc acaagctaat tacaaattgc tacagaacag
     6841 gagtaagctg aaaactgaat gccatgtttt gtttataagg tggggagggg agggaaaata
     6901 ccaaaaaact ctgttccaag tttggcattt gacattaatg tgaagcagtg ggaccatgct
     6961 gcctgctaaa ctactgtatg aatcgtaaat gttctgaaga cgagcagctg gaggctggag
     7021 gatggcattc catacagcaa aggagaagca cccaccactt catctgggaa aaggaaggaa
     7081 attgcaggag gcctggagcc atcatttgta aaggggatgt tgcggggtgt gatgctgttg
     7141 aggagattca ccttcaattg cactgctcca cagagccctc atataaggcc aatcctaatg
     7201 ggctacctcg gctttaaaag ttaatttcag taagtcctgt ttcaaaagtt tgtctttttt
     7261 tgcttctacc ttcagtgcca ctattttcca ctgcagtgtt ttgacttcac aaactgcctc
     7321 ctccagagag aacaatgtat tgctgaaaat gggcagtaga agcaaatgct gttgttacat
     7381 ttgacctata aagtattcag agtgactgct aggtagaaat taaaacttag ctttcccaaa
     7441 tagctcctta ttttgcacct tataaaaagt atactaattg ttaattagat gttgcttttg
     7501 tttatacaag cattcccaaa gaactagatt tggattttgt tttgagtttt tggattttta
     7561 aaaattatct tatttagatt gactaacagc atacttacaa ttttaaaaga agctgttgtt
     7621 cagttcatct taccagatgt gtctggcgaa gtattcaggg tttgatggac tgctttactt
     7681 tcgtttggaa gtgatagcta agtttattat actctatatt aaacaacttt gttcatttca
     7741 ctgaggacct tatcttcctt atatttcaga acaaagaagc aacaagcgtg aataaaaaga
     7801 caaatgtatt tgactccctc ataatcccca tctgtatgtg ctacccttcc ttcaaatata
     7861 taaatgtgca tctttttttt aaaaaaaaaa aaaaaaaagg ttcctcttct ggccaaattt
     7921 gatctatggt ggtatgattc atactgttaa attgagagag gaaaccttgt ggttaaaaat
     7981 tatatggctg ctgttttctt tttgcagtca gtggtcaaaa ctgatcatgt gcttaaatcg
     8041 atttttatgc acagaactag ttattgtgaa cattactgct ccctccaaag atttcctgat
     8101 aacttgggcc agaggtggtt actgagtaac aaggatctaa ttcaatgcct caaaactctt
     8161 ccacccacaa tgcaaatctt acctcacaag ctctaaccta aatcacagag acatgcatgt
     8221 ttcatgcatt aacactgatt tcgctctgtg gcccaccaga ggggtgggct catgtcccct
     8281 gactcctcac atgagtgcct cagctctaag agccgtggaa cggggggtag ggaaggtttg
     8341 cgatctggag ctcagcaact ggctcagcaa cgttttctcc atttcattag cactaaacaa
     8401 gtctcttgct ctcaggaatt tgtcagaaaa aagaataaaa tcacctgaga ctccacatac
     8461 cagattataa actcttctcg taggtttgaa ttgcttactc acatgtcata aattaaccac
     8521 agcttcattt gaccaccagg tctaaagtct gttgacagtt tcagcatgac tgaatcgctc
     8581 attttttttt tttgctttca gaaattggct tggttctctt tagagttggt gtaaacatgc
     8641 catgtaataa atgatttcca cttaatggta caacagaatt attgctttct tagatgtatg
     8701 tgtagtaaaa gtcaatatac acatttatat aatttctttc ttcaaaatct tatacctaat
     8761 ttgatatttc taaaaattgc acatgtaagt catgtgtata acatgctaaa gtactttaac
     8821 tgtgatctta aaactgaata aaaatattta ataaaacttt gaaatatttt aaagatatta
     8881 ttcaaatata tttctttatg ttcacactac tggccgtaga gtatgtgcct ttaatgtacc
     8941 attttcacta aaaacagtag gaaaaatact aataaaagta agatatttca actattttag
     9001 aacatcgaa
//
