LOCUS       XM_047432911            2838 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens Bardet-Biedl syndrome 4 (BBS4), transcript
            variant X1, mRNA.
ACCESSION   XM_047432911
VERSION     XM_047432911.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 21% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2838
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..2838
                     /gene="BBS4"
                     /note="Bardet-Biedl syndrome 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 21 ESTs, 501 long SRA reads, 11 Proteins, and 88%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 9 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:585"
                     /db_xref="HGNC:HGNC:969"
                     /db_xref="MIM:600374"
     CDS             429..1952
                     /gene="BBS4"
                     /codon_start=1
                     /product="Bardet-Biedl syndrome 4 protein isoform X1"
                     /protein_id="XP_047288867.1"
                     /db_xref="GeneID:585"
                     /db_xref="HGNC:HGNC:969"
                     /db_xref="MIM:600374"
                     /translation="MIWNTRNSTYIFTAPEFPILEKQNWLIHLHYIRKDYEACKAVIK
                     EQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLL
                     GKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYI
                     MLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALT
                     YDPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVA
                     AISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAV
                     ALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSL
                     LKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPL
                     GSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK"
ORIGIN      
        1 gcagcggtgg gctgagctaa aatggctgag gagagagtcg cgacggtgag cgccgagatt
       61 ctctttagtt gcccggccgc agggcaaggc aagctggcgg gtggcttttg tcccatgcag
      121 cggttcctgg agagaggcgg agctgggtgc cgagcgtctc agggtgggcg gggcgacacg
      181 gtcccctttt tactgtcccg ggaactggtc gcctggggca agtctggata cttagcagca
      241 caggtcctgt tctaggactg tagtccctct tggggtgcgc tggacggaga agggagactt
      301 ttcaccagta atggctctta ccgtagtgcc atctttttct gtctcggggg tttggaagag
      361 aactcaattt cctgtatcta ctgagtctca aaaaccccgg cagaaaaaag ggggagttgg
      421 agtgagcaat gatttggaat accagaaatt caacttatat atttacagct ccagagtttc
      481 ctattttgga gaagcagaac tggttgattc atcttcatta tatccggaaa gattatgaag
      541 cctgcaaggc tgttatcaaa gaacagcttc aagagactca gggattgtgt gaatatgcta
      601 tctatgtcca agcattgata tttcgcctag aaggaaatat ccaagaatcc ctagaactct
      661 tccagacatg tgcagttctt agtcctcaga gtgctgataa cctcaagcag gtggccagat
      721 ctttatttct tttgggaaaa cataaagctg ccattgaagt atataatgaa gcagctaaac
      781 tcaaccagaa agattgggag atcagccata acctaggagt ttgctacata tacctgaagc
      841 agttcaacaa ggcacaagac cagttgcaca atgccctgaa tcttaatagg cacgatctga
      901 cttatataat gctggggaag atccacttgc tggagggaga cttggacaag gccattgaag
      961 tctacaagaa agcagtggag ttctcaccag aaaatacaga gcttcttaca actttaggat
     1021 tactctactt acagctcggc atttaccaga aggcatttga acatcttggc aatgcactga
     1081 cttatgaccc taccaactac aaggccatct tggcagcagg cagcatgatg cagacccacg
     1141 gggactttga tgttgccctc accaaataca gagttgtggc ttgtgctgtt ccagaaagtc
     1201 ctccactctg gaataacatt ggaatgtgtt tctttggcaa gaagaaatat gtggcggcca
     1261 tcagctgcct gaaacgagcc aactacttgg caccctttga ttggaagatt ctgtataatt
     1321 tgggccttgt ccatttgacc atgcagcagt atgcatcagc ttttcatttt ctcagtgcgg
     1381 ccatcaactt ccagccaaag atgggggagc tctacatgct cttggcagtg gctctgacca
     1441 atctggaaga tatagaaaat gccaagagag cctacgcaga agcagtccac ctggataagt
     1501 gtaacccttt agtaaacctg aactatgctg tgctgctgta caaccagggc gagaagaaga
     1561 acgccctggc ccaatatcag gagatggaga agaaagtcag cctactcaag gacaatagct
     1621 ctctggaatt tgactctgag atggtggaga tggctcagaa gttgggagct gctctccagg
     1681 ttggggaggc actggtctgg accaaaccag ttaaagatcc caaatcaaag caccagacca
     1741 cttcaaccag caaacctgcc agtttccagc agcctctggg ctctaatcaa gctctaggac
     1801 aggcaatgtc ttcagcagct gcatacagga cgctcccctc aggtgctgga ggaacatccc
     1861 agttcacaaa gcccccatct cttcctctgg agccagagcc tgcggtggaa tcaagtccaa
     1921 ctgaaacatc agaacaaata agagagaaat aagaatagaa tgaatgaccc caaaataggg
     1981 ttttcttggg cgaggatgtg ctggattagg aaaggtgaca tgacacaggc agagcagagt
     2041 ggcacccacc acagaataca gtgtgtgtta ttacgaggag ccagcagttg agcctaaggt
     2101 ccttctacct acctggtatt ggcatttgag gtcggaaacc ctctactgcc ccataagcca
     2161 ggaaaagtga aaagagaaca cagttccttt aagaactggc agcaaggctt gaggccttat
     2221 gtatgtagct gagtcagcaa ggtacatgat gctgtctgct ttcaaaagga cttttctctc
     2281 ctagctgact gactccttcc ttagttcaag gaacagctga gacagacctc tgctgagtag
     2341 ctctgtgatg acaaagcctt ggtttaactg aggtgatcct caggttgtga ggtttattag
     2401 tccccaaggc aaacacaaat attagattaa taatccaact ttaatagtat acatttaaaa
     2461 gaaaaaaaac aaaagccctg gaagttgagg ccaagcctgc tgagtattgc agctgcattt
     2521 gcccaaaggg aatccagaac aagtccctcc ctgtattttg ttcttgagag gggtcagtct
     2581 agaagctaga tcctatcagg atgaggagca gcagcccagg gcttgtctgg atcagcacca
     2641 acgattttaa agaaaaaagg aagagtttct tagatgagta attgttattg aagatagtca
     2701 gtgataacca ctgaccagat gctatcaata cactatgtgt cctttttaga ataaagatta
     2761 catatcatca ttcctttggg gaaaattgtt attcaggtat aaaaacaaga gatcataata
     2821 aaaacctaaa agaaccta
//
